Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 7, 2013, Pages

  Xie, Chaoqin ^a   Biary, Nora ^a   Tocchetti, Carlo G ^b   Aon, Miguel A ^b   Paolocci, Nazareno ^b   Kauffman, Justin ^a   Akar, Fadi G ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Arrhythmias; Conduction; Electrical remodeling; Insulin; Oxidative stress; Repolarization; Type 1 diabetes mellitus

Indexed keywords

DIAMIDE; GLUCOSE; GLUTATHIONE; INSULIN GLARGINE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL GUINEA PIG; GLUCOSE BLOOD LEVEL; HEART ARRHYTHMIA; HEART CONDUCTION; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HYPERGLYCEMIA; MALE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ACTION POTENTIALS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLOOD GLUCOSE; DIAMIDE; GLUTATHIONE; GUINEA PIGS; HEART; HYPERGLYCEMIA; INSULIN; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROPENSITY SCORE; STREPTOZOCIN; TACHYCARDIA, VENTRICULAR; VENTRICULAR FIBRILLATION; VENTRICULAR REMODELING;

EID: 84878573783     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00026.2012     Document Type: Article

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