Incidence and risk factors of prolonged QTc interval in type 1 diabetes: The EURODIAB prospective complications study

Diabetes Care

Volumn 30, Issue 8, 2007, Pages 2057-2063

  Giunti, Sara ^a   Bruno, Graziella ^a   Lillaz, Emma ^a   Gruden, Gabriella ^a   Lolli, Valentina ^a   Chaturvedi, Nish ^b   Fuller, John H ^c,e   Veglio, Massimo ^d   Cavallo Perin, Paolo ^a   Karamanos, B ^e   Sjolie, A K ^e   Chaturvedi, N ^e   Toeller, M ^e   Pozza, G ^e   Ferriss, B ^e   Porta, M ^e   Rottiers, R ^e   Michel, G ^e  

^a UNIVERSITY OF TURIN   (Italy)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d Ospedale Evangelico Valdese   (Italy)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C;

ADULT; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; COHORT ANALYSIS; DIABETIC NEUROPATHY; FEMALE; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTENSION; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PHYSICAL ACTIVITY; QT INTERVAL; QT PROLONGATION; RISK ASSESSMENT; SEX DIFFERENCE;

EID: 34547683963     PISSN: 01495992     EISSN: 01495992     Source Type: Journal    
DOI: 10.2337/dc07-0063     Document Type: Article

References (28)

1. Schouten EG, Dekker JM, Meppelink P, Kok FJ, Vandenbroucke JP, Pool J: QT interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation 84:1516-1523, 1991
2. Okin PM, Devereux RB, Lee ET, Galloway JM, Howard BV: Electrocardiographic repolarization complexity and abnormality predict all-cause and cardiovascular mortality in diabetes: the Strong Heart Study. Diabetes 53:434-440, 2004
3. Salles GF, Bloch KV, Cardoso CR: Mortality and predictors of mortality in a cohort of Brazilian type 2 diabetic patients. Diabetes Care 27:1299-1305, 2004
4. Rossing P, Breum L, Major-Pedersen A, Sato A, Winding H, Pietersen A, Kastrup J, Parving HH: Prolonged QTc interval predicts mortality in patients with type 1 diabetes mellitus. Diabet Med 18:199-205, 2001
5. Sawicki PT, Dahne R, Bender R, Berger M: Prolonged QT interval as a predictor of mortality in diabetic nephropathy. Diabetologia 39:77-81, 1996
6. Veglio M, Sivieri R, Chinaglia A, Scaglione L, Cavallo-Perin P: QT interval prolongation and mortality in type 1 diabetic patients: a 5-year cohort prospective study. Neuropathy Study Group of the Italian Society of the Study of Diabetes, Piemonte Affiliate. Diabetes Care 23:1381-1383, 2000
7. Rana BS, Lim PO, Naas AA, Ogston SA, Newton RW, Jung RT, Morris AD, Struthers AD: QT interval abnormalities are often present at diagnosis in diabetes and are better predictors of cardiac death than ankle brachial pressure index and autonomic function tests. Heart 91:44-50, 2005
8. Benoit SR, Mendelsohn AB, Nourjah P, Staffa JA, Graham DJ: Risk factors for prolonged QTc among US adults: third National Health and Nutrition Examination Survey. Eur J Cardiovasc Prev Rehabil 12:363-368, 2005
9. Suys B, Heuten S, De Wolf D, Verherstraeten M, de Beeck LO, Matthys D, Vrints C, Rooman R: Glycemia and corrected QT interval prolongation in young type 1 diabetic patients: what is the relation? Diabetes Care 29:427-429, 2006
10. Veglio M, Chinaglia A, Cavallo-Perin P: QT interval, cardiovascular risk factors and risk of death in diabetes. J Endocrinol Invest 27:175-181, 2004
11. Chiang CE, Roden DM: The long QT syndromes: genetic basis and clinical implications. J Am Coll Cardiol 36:1-12, 2000
12. Veglio M, Borra M, Stevens LK, Fuller JH, Perin PC: The relation between QTc interval prolongation and diabetic complications: the EURODIAB IDDM Complication Study Group. Diabetologia 42:68-75, 1999
13. Soedamah-Muthu SS, Chaturvedi N, Toeller M, Ferriss B, Reboldi P, Michel G, Manes C, Fuller JH: Risk factors for coronary heart disease in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study. Diabetes Care 27:530-537, 2004
14. Aldington SJ, Kohner EM, Meuer S, Klein R, Sjolie AK: Methodology for retinal photography and assessment of diabetic retinopathy: the EURODIAB IDDM Complications Study. Diabetologia 38:437-444, 1995
15. Tesfaye S, Stevens LK, Stephenson JM, Fuller JH, Plater M, Ionescu-Tirgoviste C, Nuber A, Pozza G, Ward JD: Prevalence of diabetic peripheral neuropathy and its relation to glycaemic control and potential risk factors: the EURODIAB IDDM Complications Study. Diabetologia 39:1377-1384, 1996
16. Koivisto VA, Stevens LK, Mattock M, Ebeling P, Muggeo M, Stephenson J, Idzior-Walus B: Cardiovascular disease and its risk factors in IDDM in Europe: EURODIAB IDDM Complications Study Group. Diabetes Care 19:689-697, 1996
17. Norman JE Jr, Levy D: Improved electrocardiographic detection of echocardiographic left ventricular hypertrophy: results of a correlated data base approach. J Am Coll Cardiol 26:1022-1029, 1995
18. Giunti S, Bruno G, Veglio M, Gruden G, Webb DJ, Livingstone S, Chaturvedi N, Fuller JH, Perin PC: Electrocardiographic left ventricular hypertrophy in type 1 diabetes: prevalence and relation to coronary heart disease and cardiovascular risk factors: the Eurodiab IDDM Complications Study. Diabetes Care 28:2255-2257, 2005
19. Bazett H: An analysis of time-relations of electrocardiograms. Hearts 7:353-370, 1920
20. Vrtovec B, Delgado R, Zewail A, Thomas CD, Richartz BM, Radovancevic B: Prolonged QTc interval and high B-type natriuretic peptide levels together predict mortality in patients with advanced heart failure. Circulation 107:1764-1769, 2003
21. Rothman KJ: Modern Epidemiology. Boston, MA, Little, Brown, and Company, 1986
22. Bruno G, Giunti S, Bargero G, Ferrero S, Pagano G, Perin PC: Sex-differences in prevalence of electrocardiographic left ventricular hypertrophy in type 2 diabetes: the Casale Monferrato Study. Diabet Med 21:823-828, 2004
23. Griffin M, Lee HW, Zhao L, Eghbali-Webb M: Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen. Mol Cell Biochem 215:21-30, 2000
24. Kadokami T, McTiernan CF, Kubota T, Frye CS, Feldman AM: Sex-related survival differences in murine cardiomyopathy are associated with differences in TNF-receptor expression. J Clin Invest 106:589-597, 2000
25. Schuit AJ, Dekker JM, de Vegt F, Verheij TC, Rijneke RD, Schouten EG: Effect of physical training on QTc interval in elderly people. J Electrocardiol 31:111-116, 1998
26. Swenne I, Larsson PT: Heart risk associated with weight loss in anorexia nervosa and eating disorders: risk factors for QTc interval prolongation and dispersion. Acta Paediatr 88:304-309, 1999
27. Marfella R, Nappo F, De Angelis L, Siniscalchi M, Rossi F, Giugliano D: The effect of acute hyperglycaemia on QTc duration in healthy man. Diabetologia 43:571-575, 2000
28. Dekker JM, Crow RS, Hannan PJ, Schouten EG, Folsom AR; ARIC Study: Heart rate-corrected QT interval prolongation predicts risk of coronary heart disease in black and white middle-aged men and women: the ARIC Study. J Am Coll Cardiol 43:565-571, 2004