-
1
-
-
0242720407
-
PAD, a growing family of citrullinating enzymes: Genes, features and involvement in disease
-
DOI 10.1002/bies.10357
-
Vossenaar, E. R., Zendman, A. J., van Venrooij, W. J. & Pruijn, G. J. PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 25, 1106-1118 (2003). (Pubitemid 37411770)
-
(2003)
BioEssays
, vol.25
, Issue.11
, pp. 1106-1118
-
-
Vossenaar, E.R.1
Zendman, A.J.W.2
Van Venrooij, W.J.3
Pruijn, G.J.M.4
-
2
-
-
3543004695
-
2+-induced activation of human PAD4
-
DOI 10.1038/nsmb799
-
Arita, K. et al. Structural basis for Ca(2)-induced activation of human PAD4. Nat. Struct. Mol. Biol. 11, 777-783 (2004). (Pubitemid 39014504)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.8
, pp. 777-783
-
-
Arita, K.1
Hashimoto, H.2
Shimizu, T.3
Nakashima, K.4
Yamada, M.5
Sato, M.6
-
3
-
-
34948865716
-
Citrullination by peptidylarginine deiminase in rheumatoid arthritis
-
DOI 10.1196/annals.1422.034, Autoimmunity, Part D: Autoimmune Disease, Annus Mirabilis
-
Suzuki, A., Yamada, R. & Yamamoto, K. Citrullination by peptidylarginine deiminase in rheumatoid arthritis. Ann. N. Y. Acad. Sci. 1108, 323-339 (2007). (Pubitemid 47528745)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1108
, pp. 323-339
-
-
Suzuki, A.1
Yamada, R.2
Yamamoto, K.3
-
4
-
-
33745331328
-
Citrullination: A posttranslational modification in health and disease
-
DOI 10.1016/j.biocel.2006.03.008, PII S1357272506000938
-
Gyorgy, B., Toth, E., Tarcsa, E., Falus, A. & Buzas, E. I. Citrullination: a posttranslational modification in health and disease. Int. J. Biochem. Cell Biol. 38, 1662-1677 (2006). (Pubitemid 43947646)
-
(2006)
International Journal of Biochemistry and Cell Biology
, vol.38
, Issue.10
, pp. 1662-1677
-
-
Gyorgy, B.1
Toth, E.2
Tarcsa, E.3
Falus, A.4
Buzas, E.I.5
-
5
-
-
0036295234
-
Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes
-
DOI 10.1006/bbrc.2001.6303
-
Hagiwara, T., Nakashima, K., Hirano, H., Senshu, T. & Yamada, M. Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes. Biochem. Biophys. Res. Commun. 290, 979-983 (2002). (Pubitemid 34687458)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.290
, Issue.3
, pp. 979-983
-
-
Hagiwara, T.1
Nakashima, K.2
Hirano, H.3
Senshu, T.4
Yamada, M.5
-
6
-
-
0037147140
-
Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes
-
DOI 10.1074/jbc.M208795200
-
Nakashima, K., Hagiwara, T. & Yamada, M. Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes. J. Biol. Chem. 277, 49562-49568 (2002). (Pubitemid 36014395)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49562-49568
-
-
Nakashima, K.1
Hagiwara, T.2
Yamada, M.3
-
7
-
-
5044228483
-
Human PAD4 regulates histone arginine methylation levels via demethylimination
-
DOI 10.1126/science.1101400
-
Wang, Y. et al. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306, 279-283 (2004). (Pubitemid 39336873)
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 279-283
-
-
Wang, Y.1
Wysocka, J.2
Sayegh, J.3
Lee, Y.-H.4
Pertin, J.R.5
Leonelli, L.6
Sonbuchner, L.S.7
McDonald, C.H.8
Cook, R.G.9
Dou, Y.10
Roeder, R.G.11
Clarke, S.12
Stallcup, M.R.13
Allis, C.D.14
Coonrod, S.A.15
-
8
-
-
4444372638
-
Histone deimination antagonizes arginine methylation
-
DOI 10.1016/j.cell.2004.08.020, PII S0092867404007998
-
Cuthbert, G. L. et al. Histone deimination antagonizes arginine methylation. Cell 118, 545-553 (2004). (Pubitemid 39179708)
-
(2004)
Cell
, vol.118
, Issue.5
, pp. 545-553
-
-
Cuthbert, G.L.1
Daujat, S.2
Snowden, A.W.3
Erdjument-Bromage, H.4
Hagiwara, T.5
Yamada, M.6
Schneider, R.7
Gregory, P.D.8
Tempst, P.9
Bannister, A.J.10
Kouzarides, T.11
-
9
-
-
47949123469
-
Regulation of p53 target gene expression by peptidylarginine deiminase 4
-
Li, P. et al. Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol. Cell. Biol. 28, 4745-4758 (2008).
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 4745-4758
-
-
Li, P.1
-
10
-
-
49749112990
-
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis
-
Yao, H. et al. Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis. J. Biol. Chem. 283, 20060-20068 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 20060-20068
-
-
Yao, H.1
-
11
-
-
70249133329
-
Functional connection between deimination and deacetylation of histones
-
Denis, H. et al. Functional connection between deimination and deacetylation of histones. Mol. Cell. Biol. 29, 4982-4993 (2009).
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 4982-4993
-
-
Denis, H.1
-
12
-
-
77952954497
-
Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression
-
Li, P. et al. Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression. Oncogene 29, 3153-3162 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 3153-3162
-
-
Li, P.1
-
13
-
-
79959821077
-
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells
-
Zhang, X. et al. Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells. PLoS Genet. 7, e1002112 (2011).
-
(2011)
PLoS Genet
, vol.7
-
-
Zhang, X.1
-
14
-
-
0033600723
-
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3
-
Nakashima, K. et al. Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3). J. Biol. Chem. 274, 27786-27792 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 27786-27792
-
-
Nakashima, K.1
-
15
-
-
1842453329
-
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages
-
DOI 10.1136/ard.2003.012211
-
Vossenaar, E. R. et al. Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages. Ann. Rheum. Dis. 63, 373-381 (2004). (Pubitemid 38453302)
-
(2004)
Annals of the Rheumatic Diseases
, vol.63
, Issue.4
, pp. 373-381
-
-
Vossenaar, E.R.1
Radstake, T.R.D.2
Van Der Heijden, A.3
Van Mansum, M.A.M.4
Dieteren, C.5
De Rooij, D.-J.6
Barrera, P.7
Zendman, A.J.W.8
Van Venrooij, W.J.9
-
16
-
-
0042667153
-
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
-
DOI 10.1038/ng1206
-
Suzuki, A. et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat. Genet. 34, 395-402 (2003). (Pubitemid 36935332)
-
(2003)
Nature Genetics
, vol.34
, Issue.4
, pp. 395-402
-
-
Suzuki, A.1
Yamada, R.2
Chang, X.3
Tokuhiro, S.4
Sawada, T.5
Suzuki, M.6
Nagasaki, M.7
Nakayama-Hamada, M.8
Kawaida, R.9
Ono, M.10
Ohtsuki, M.11
Furukawa, H.12
Yoshino, S.13
Yukioka, M.14
Tohma, S.15
Matsubara, T.16
Wakitani, S.17
Teshima, R.18
Nishioka, Y.19
Sekine, A.20
Iida, A.21
Takahashi, A.22
Tsunoda, T.23
Nakamura, Y.24
Yamamoto, K.25
more..
-
17
-
-
70149086262
-
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
-
Jones, J. E., Causey, C. P., Knuckley, B., Slack-Noyes, J. L. & Thompson, P. R. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential. Curr. Opin. Drug Discov. Devel. 12, 616-627 (2009).
-
(2009)
Curr. Opin. Drug Discov. Devel
, vol.12
, pp. 616-627
-
-
Jones, J.E.1
Causey, C.P.2
Knuckley, B.3
Slack-Noyes, J.L.4
Thompson, P.R.5
-
18
-
-
0032960781
-
The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues
-
Girbal-Neuhauser, E. et al. The epitopes targeted by the rheumatoid arthritisassociated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues. J. Immunol. 162, 585-594 (1999). (Pubitemid 29018970)
-
(1999)
Journal of Immunology
, vol.162
, Issue.1
, pp. 585-594
-
-
Girbal-Neuhauser, E.1
Durieux, J.-J.2
Arnaud, M.3
Dalbon, P.4
Sebbag, M.5
Vincent, C.6
Simon, M.7
Senshu, T.8
Masson-Bessiere, C.9
Jolivet-Reynaud, C.10
Jolivet, M.11
Serre, G.12
-
19
-
-
0031974911
-
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
-
Schellekens, G. A., de Jong, B. A., van den Hoogen, F. H., van de Putte, L. B. & van Venrooij, W. J. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J. Clin. Invest. 101, 273-281 (1998). (Pubitemid 28058927)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.1
, pp. 273-281
-
-
Schellekens, G.A.1
De Jong, B.A.W.2
Van Den Hoogen, F.H.J.3
Van De Putte, L.B.A.4
Van Venrooij, W.J.5
-
20
-
-
73249145617
-
Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis
-
Wegner, N. et al. Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis. Immunol. Rev. 233, 34-54 (2010).
-
(2010)
Immunol. Rev
, vol.233
, pp. 34-54
-
-
Wegner, N.1
-
21
-
-
60849099332
-
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
-
Wang, Y. et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J. Cell. Biol. 184, 205-213 (2009).
-
(2009)
J. Cell. Biol
, vol.184
, pp. 205-213
-
-
Wang, Y.1
-
22
-
-
77956245423
-
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
-
Li, P. et al. PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J. Exp. Med. 207, 1853-1862 (2010).
-
(2010)
J. Exp. Med
, vol.207
, pp. 1853-1862
-
-
Li, P.1
-
23
-
-
79957951714
-
Suppression of colitis in mice by Cl-amidine: A novel peptidylarginine deiminase inhibitor
-
Chumanevich, A. A. et al. Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. Am. J. Physiol. Gastrointest. Liver Physiol. 300, G929-G938 (2011).
-
(2011)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.300
-
-
Chumanevich, A.A.1
-
24
-
-
79955006474
-
N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis
-
Willis, V. C. et al. N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-L- ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. J. Immunol. 186, 4396-4404 (2011).
-
(2011)
J. Immunol
, vol.186
, pp. 4396-4404
-
-
Willis, V.C.1
-
25
-
-
84864386137
-
Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity
-
Wang, Y. et al. Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity. J. Biol. Chem. 287, 25941-25953 (2012).
-
(2012)
J. Biol. Chem
, vol.287
, pp. 25941-25953
-
-
Wang, Y.1
-
26
-
-
0037071398
-
The proto-oncogene c-myc in hematopoietic development and leukemogenesis
-
DOI 10.1038/sj.onc.1205400
-
Hoffman, B., Amanullah, A., Shafarenko, M. & Liebermann, D. A. The protooncogene c-myc in hematopoietic development and leukemogenesis. Oncogene 21, 3414-3421 (2002). (Pubitemid 34587713)
-
(2002)
Oncogene
, vol.21
, Issue.21 REV. ISSUE 2
, pp. 3414-3421
-
-
Hoffman, B.1
Amanullah, A.2
Shafarenko, M.3
Liebermann, D.A.4
-
27
-
-
8644219660
-
C-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
-
DOI 10.1101/gad.313104
-
Wilson, A. et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev. 18, 2747-2763 (2004). (Pubitemid 39507768)
-
(2004)
Genes and Development
, vol.18
, Issue.22
, pp. 2747-2763
-
-
Wilson, A.1
Murphy, M.J.2
Oskarsson, T.3
Kaloulis, K.4
Bettess, M.D.5
Oser, G.M.6
Pasche, A.-C.7
Knabenhans, C.8
MacDonald, H.R.9
Trumpp, A.10
-
28
-
-
41149125490
-
A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis
-
DOI 10.1084/jem.20071875
-
Petropoulos, K. et al. A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis. J. Exp. Med. 205, 515-522 (2008). (Pubitemid 351439299)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.3
, pp. 515-522
-
-
Petropoulos, K.1
Arseni, N.2
Schessl, C.3
Stadler, C.R.4
Rawat, V.P.S.5
Deshpande, A.J.6
Heilmeier, B.7
Hiddemann, W.8
Quintanilla-Martinez, L.9
Bohlander, S.K.10
Feuring-Buske, M.11
Buske, C.12
-
29
-
-
36248934318
-
The c-myc Promoter: Still MysterY and Challenge
-
DOI 10.1016/S0065-230X(07)99004-1, PII S0065230X07990041
-
Wierstra, I. & Alves, J. The c-myc promoter: still MysterY and challenge. Adv. Cancer Res. 99, 113-333 (2008). (Pubitemid 350137254)
-
(2008)
Advances in Cancer Research
, vol.99
, pp. 113-333
-
-
Wierstra, I.1
Alves, J.2
-
30
-
-
0033817339
-
Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator
-
Billin, A. N., Thirlwell, H. & Ayer, D. E. Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator. Mol. Cell Biol. 20, 6882-6890 (2000).
-
(2000)
Mol. Cell Biol
, vol.20
, pp. 6882-6890
-
-
Billin, A.N.1
Thirlwell, H.2
Ayer, D.E.3
-
31
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
DOI 10.1016/j.cell.2005.05.026, PII S0092867405005404
-
Kiel, M. J. et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121 (2005). (Pubitemid 40884400)
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 1109-1121
-
-
Kiel, M.J.1
Yilmaz, O.H.2
Iwashita, T.3
Yilmaz, O.H.4
Terhorst, C.5
Morrison, S.J.6
-
32
-
-
45149123052
-
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
-
DOI 10.1084/jem.20080277
-
Thompson, B. J. et al. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7. J. Exp. Med. 205, 1395-1408 (2008). (Pubitemid 351831495)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1395-1408
-
-
Thompson, B.J.1
Jankovic, V.2
Gao, J.3
Buonamici, S.4
Vest, A.5
Lee, J.M.6
Zavadil, J.7
Nimer, S.D.8
Aifantis, I.9
-
33
-
-
33751001725
-
Histone citrullination by protein arginine deiminase: Is arginine methylation a green light or a roadblock?
-
Thompson, P. R. & Fast, W. Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock? ACS Chem. Biol. 1, 433-441 (2006).
-
(2006)
ACS Chem. Biol
, vol.1
, pp. 433-441
-
-
Thompson, P.R.1
Fast, W.2
-
34
-
-
36649002031
-
Loss of β-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo
-
DOI 10.1016/j.ccr.2007.11.003, PII S1535610807003340
-
Zhao, C. et al. Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell 12, 528-541 (2007). (Pubitemid 350199070)
-
(2007)
Cancer Cell
, vol.12
, Issue.6
, pp. 528-541
-
-
Zhao, C.1
Blum, J.2
Chen, A.3
Kwon, H.Y.4
Jung, S.H.5
Cook, J.M.6
Lagoo, A.7
Reya, T.8
-
35
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
DOI 10.1038/nature03319
-
Reya, T. & Clevers, H. Wnt signalling in stem cells and cancer. Nature 434, 843-850 (2005). (Pubitemid 40558990)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
36
-
-
48749101937
-
WNT signalling in the immune system: WNT is spreading its wings
-
Staal, F. J., Luis, T. C. & Tiemessen, M. M. WNT signalling in the immune system: WNT is spreading its wings. Nat. Rev. Immunol. 8, 581-593 (2008).
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 581-593
-
-
Staal, F.J.1
Luis, T.C.2
Tiemessen, M.M.3
-
37
-
-
34347241381
-
Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-α-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1
-
DOI 10.1210/me.2006-0550
-
Dong, S., Zhang, Z. & Takahara, H. Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alpha-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1. Mol. Endocrinol. 21, 1617-1629 (2007). (Pubitemid 47001086)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.7
, pp. 1617-1629
-
-
Dong, S.1
Zhang, Z.2
Takahara, H.3
-
38
-
-
72249096427
-
Regulation of protein Citrullination through p53/PADI4 network in DNA damage response
-
Tanikawa, C. et al. Regulation of protein Citrullination through p53/PADI4 network in DNA damage response. Cancer Res. 69, 8761-8769 (2009).
-
(2009)
Cancer Res
, vol.69
, pp. 8761-8769
-
-
Tanikawa, C.1
-
39
-
-
84863393260
-
Regulation of histone modification and chromatin structure by the p53-PADI4 pathway
-
Tanikawa, C. et al. Regulation of histone modification and chromatin structure by the p53-PADI4 pathway. Nat. Commun. 3, 676 (2012).
-
(2012)
Nat. Commun
, vol.3
, pp. 676
-
-
Tanikawa, C.1
-
40
-
-
79951578893
-
Protein arginine deiminase 4: A target for an epigenetic cancer therapy
-
Slack, J. L., Causey, C. P. & Thompson, P. R. Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cell Mol. Life Sci. 68, 709-720 (2011).
-
(2011)
Cell Mol. Life Sci
, vol.68
, pp. 709-720
-
-
Slack, J.L.1
Causey, C.P.2
Thompson, P.R.3
-
41
-
-
59149104026
-
Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias
-
Li, Z. et al. Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias. Cancer Res. 69, 1109-1116 (2009).
-
(2009)
Cancer Res
, vol.69
, pp. 1109-1116
-
-
Li, Z.1
|