Synthesis and antibacterial evaluation of novel pleuromutilin derivatives

European Journal of Medicinal Chemistry

Volumn 63, Issue , 2013, Pages 231-238

  Shang, Ruofeng ^a   Liu, Yu ^a   Xin, Zhijun ^b   Guo, Wenzhu ^a   Guo, Zhiting ^a   Hao, Baocheng ^a   Jianping, Liang ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b INSTITUTE OF MODERN PHYSICS   (China)

Author keywords

Acylation reaction; Antibacterial activity; Antibiotics; Pleuromutilin derivative; Synthesis

Indexed keywords

14 O (PARA TOLUENE SULFONYLOXYACETYL)MUTILIN; 14 O [(1 AMINO 2 METHYLPROPANE 2 YL)THIOACETYL]MUTILIN; 14 O [(2 AMINOBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(2 CHLOROBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(2 INDOLEAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(2 METHOXYBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(2 METHYLBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(3 AMINOBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(3 CHLOROBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(3 METHOXYBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(3 METHYLBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(4 AMINOBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(4 CHLOROBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(4 METHOXYBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(4 METHYLBENZAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [(PHENYLGLYCINAMIDE 2 METHYLPROPANE 2 YL)THIOACETATE]MUTILIN; 14 O [1 N CARBAMATE ISOBUTYL 2 METHYLPROPANE 2 YL]THIOACETATE]MUTILIN; BC 3205; BC 3781; BC 7013; PLEUROMUTILIN; RETAPAMULIN; TIAMULIN; UNCLASSIFIED DRUG; VALUNEMULIN;

AGAR DILUTION; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS AGALACTIAE;

ANTI-BACTERIAL AGENTS; BENZAMIDES; DITERPENES; ESCHERICHIA COLI; METHICILLIN RESISTANCE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; POLYCYCLIC COMPOUNDS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS AGALACTIAE;

EID: 84878559354     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.01.048     Document Type: Article

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