Development of a pulmonary peptide delivery system using porous nanoparticle-aggregate particles for systemic application

International Journal of Pharmaceutics

Volumn 451, Issue 1-2, 2013, Pages 104-111

  Yang, Likai ^a   Luo, Jing ^a   Shi, Sanjun ^a   Zhang, Qiang ^b   Sun, Xun ^a   Zhang, Zhirong ^a   Gong, Tao ^a,c  

^a SICHUAN UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Hydrophobic ion pair complex; Nanostructured lipid carriers; Pulmonary drug delivery; Spray freeze drying

Indexed keywords

ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; DRUG CARRIER; NANOPARTICLE; OCTREOTIDE; POROUS NANOPARTICLE AGGREGATE PARTICLE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; FREEZE DRYING; HYDROPHOBICITY; LIPOPHILICITY; LIVER HOMOGENATE; LIVER ISCHEMIA; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PARTICLE SIZE; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, INHALATION; ANIMALS; AREA UNDER CURVE; ASPARTATE AMINOTRANSFERASES; DISEASE MODELS, ANIMAL; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; FREEZE DRYING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INJECTIONS, SUBCUTANEOUS; LIVER; NANOPARTICLES; OCTREOTIDE; PARTICLE SIZE; POROSITY; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 84878538677     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.077     Document Type: Article

References (38)

1. M. Beck-Broichsitter, C. Schweiger, T. Schmehl, T. Gessler, W. Seeger, and T. Kissel Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery J. Control. Release 2011
2. R. Bi, W. Shao, Q. Wang, and N. Zhang Spray-freeze-dried dry powder inhalation of insulin-loaded liposomes for enhanced pulmonary delivery J. Drug Target. 16 2008 639 648
3. R. Bi, W. Shao, Q. Wang, and N. Zhang Solid lipid nanoparticles as insulin inhalation carriers for enhanced pulmonary delivery J. Biomed. Nanotechnol. 5 2009 84 92
4. M. Bivas-Benita, R. Zwier, H.E. Junginger, and G. Borchard Non-invasive pulmonary aerosol delivery in mice by the endotracheal route Eur. J. Pharm. Biopharm. 61 2005 214 218
5. C. Bloechle, K. Kusterer, T. Konrad, S. Hosch, J. Izbicki, W. Knoefel, C. Broelsch, and K. Usadel Rat liver injury induced by hypoxic ischemia and reperfusion: protective action by somatostatins is independent from changes in glucose metabolism Horm. Metab. Res. 26 1994 270 275
6. C. Bosquillon, V. Préat, and R. Vanbever Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats J. Control. Release 96 2004 233 244
7. W.G. Dai, and L.C. Dong Characterization of physiochemical and biological properties of an insulin/lauryl sulfate complex formed by hydrophobic ion pairing Int. J. Pharm. 336 2007 58 66
8. D.A. Edwards, A. Ben-Jebria, and R. Langer Recent advances in pulmonary drug delivery using large, porous inhaled particles J. Appl. Physiol. 85 1998 379 385
9. T. Govender, S. Stolnik, M.C. Garnett, L. Illum, and S.S. Davis PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug J. Control. Release 57 1999 171 185
10. N. Hodoshima, C. Udagawa, T. Ando, H. Fukuyasu, H. Watanabe, and S. Nakabayashi Lipid nanoparticles for delivering antitumor drugs Int. J. Pharm. 146 1997 81 92
11. F.-Q. Hu, S.-P. Jiang, Y.-Z. Du, H. Yuan, Y.-Q. Ye, and S. Zeng Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system Colloids Surf. B: Biointerfaces 45 2005 167 173
12. Y.-Y. Huang, and C.-H. Wang Pulmonary delivery of insulin by liposomal carriers J. Control. Release 113 2006 9 14
13. A. Kaçmaz, A. Polat, Y. User, M. Tilki, S. Özkan, and G. Şener Octreotide: a new approach to the management of acute abdominal hypertension Peptides 24 2003 1381 1386
14. A. Kaçmaz, A. Polat, Y. User, M. Tilki, S. Özkan, and G. Şener Octreotide improves reperfusion-induced oxidative injury in acute abdominal hypertension in rats J. Gastrointest. Surg. 8 2004 113 119
15. K. Kusterer, C. Blöchle, T. Konrad, K.D. Palitzsch, and K.H. Usadel Rat liver injury induced by hypoxic ischemia and reperfusion: protective action by somatostatin and two derivatives Regul. Pept. 44 1993 251 256
16. I. Landa, J. Arias, M. Gómez, M. Quadros, A. Moreno, and J.L. Balibrea Cytoprotective effect of somatostatin in a rat model of hepatic ischemic reperfusion Hepatology 16 1992 1474 1476
17. J. Lee, Y.J. Oh, S.K. Lee, and K.Y. Lee Facile control of porous structures of polymer microspheres using an osmotic agent for pulmonary delivery J. Control. Release 146 2010 61 67
18. Y.Z. Li, X. Sun, T. Gong, J. Liu, J. Zuo, and Z.R. Zhang Inhalable microparticles as carriers for pulmonary delivery of thymopentin-loaded solid lipid nanoparticles Pharm. Res. 2010 1 10
19. J. Liu, T. Gong, C. Wang, Z. Zhong, and Z. Zhang Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization Int. J. Pharm. 340 2007 153 162
20. R. Müller, K. Mäder, A. Lippacher, and V. Jenning Solid-liquid (semi-solid) lipid particles and method of producing highly concentrated lipid particle dispersions Ger. Patent Appl. 199 2000 203
21. R.H. Müller, M. Radtke, and S.A. Wissing Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations Adv. Drug Deliver. Rev. 54 Suppl. 2002 S131 S155
22. J. Matsuura, M.E. Powers, M.C. Manning, and E. Shefter Structure and stability of insulin dissolved in 1-octanol J. Am. Chem. Soc. 115 1993 1261 1264
23. J.S. Patton, and R.M. Platz (D) Routes of delivery Case studies::(2) pulmonary delivery of peptides and proteins for systemic action Adv. Drug Deliver. Rev. 8 1992 179 196
24. J.S. Patton, P. Trinchero, and R.M. Platz Bioavailability of pulmonary delivered peptides and proteins: α-interferon, calcitonins and parathyroid hormones J. Control. Release 28 1994 79 85
25. Q. Peng, Z.R. Zhang, T. Gong, G.Q. Chen, and X. Sun A rapid-acting, long-acting insulin formulation based on a phospholipid complex loaded PHBHHx nanoparticles Biomaterials 2011
26. Q. Peng, Z.R. Zhang, X. Sun, J. Zuo, D. Zhao, and T. Gong Mechanisms of phospholipid complex loaded nanoparticles enhancing the oral bioavailability Mol. Pharmacol. 7 2010 565 575
27. M.E. Powers, J. Matsuura, J. Brassell, M.C. Manning, and E. Shefter Enhanced solubility of proteins and peptides in nonpolar solvents through hydrophobic ion pairing Biopolymers 33 1993 927 932
28. M. Radtke, and R.H. Müller Nanostructured lipid drug carriers New Drugs 2 2001 48 52
29. J.C. Sung, B.L. Pulliam, and D.A. Edwards Nanoparticles for drug delivery to the lungs Trends Biotechnol. 25 2007 563 570
30. S. Tomita, R.K. Li, R.D. Weisel, D.A.G. Mickle, E.J. Kim, T. Sakai, and Z.Q. Jia Autologous transplantation of bone marrow cells improves damaged heart function Circulation 100 1999 II-247 II-256
31. N. Tsapis, D. Bennett, B. Jackson, D.A. Weitz, and D. Edwards Trojan particles: large porous carriers of nanoparticles for drug delivery Proc. Natl. Acad. Sci. U. S. A. 99 2002 12001
32. F. Ungaro, I. d'Angelo, C. Coletta, R.E.V. Bianca, R. Sorrentino, B. Perfetto, M.A. Tufano, A. Miro, M.I. La Rotonda, and F. Quaglia Dry powders based on PLGA nanoparticles for pulmonary delivery of antibiotics: modulation of encapsulation efficiency, release rate and lung deposition pattern by hydrophilic polymers J. Control. Release 2011
33. J.L. Vázquez, S. Merino, Ò. Doměnech, M. Berlanga, M. Viñas, M.T. Montero, and J. Hernández-Borrell Determination of the partition coefficients of a homologous series of ciprofloxacin: influence of the N-4 piperazinyl alkylation on the antimicrobial activity Int. J. Pharm. 220 2001 53 62
34. 1990. Process for Producing Small Particles of Biologically Active Molecules. WO Patent WO/1990/013,285.
35. A.J.J. Wood, S.W.J. Lamberts, A.J. van der Lely, W.W. de Herder, and L.J. Hofland Octreotide N. Engl. J. Med. 334 1996 246 254
36. Y. Yang, N. Bajaj, P. Xu, K. Ohn, M.D. Tsifansky, and Y. Yeo Development of highly porous large PLGA microparticles for pulmonary drug delivery Biomaterials 30 2009 1947 1953
37. H.S. Yoo, H.K. Choi, and T.G. Park Protein-fatty acid complex for enhanced loading and stability within biodegradable nanoparticles J. Pharm. Sci. 90 2001 194 201
38. H. Yuan, S.P. Jiang, Y.Z. Du, J. Miao, X.G. Zhang, and F.Q. Hu Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles Colloids Surf. B: Biointerfaces 70 2009 248 253