Reactivity of chemical sensitizers toward amino acids in Cellulo plays a role in the activation of the Nrf2-ARE pathway in human monocyte dendritic cells and the THP-1 cell line

Toxicological Sciences

Volumn 133, Issue 2, 2013, Pages 259-274

  Migdal, Camille ^a   Botton, Jérémie ^b   El Ali, Zeina ^a   Azoury, Marie Eliane ^a   Guldemann, Joan ^c   Giménez Arnau, Elena ^c   Lepoittevin, Jean Pierre ^c   Kerdine Römer, Saadia ^a   Pallardy, Marc ^a  

^a INSERM   (France)

^b CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Chemical sensitizer reactivity; Dendritic cells; Nrf2

Indexed keywords

CYSTEINE; HAPTEN; HEME OXYGENASE 1; LYSINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SINEFUNGIN; TRANSCRIPTION FACTOR NRF2;

ARTICLE; BINDING AFFINITY; BONE MARROW CELL; CELL VIABILITY; CONTROLLED STUDY; DENDRITIC CELL; DETOXIFICATION; ELECTROPHILICITY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MONOCYTE; PHENOTYPE; PROTEIN EXPRESSION; SENSITIZATION; SIGNAL TRANSDUCTION;

CHEMICAL SENSITIZER REACTIVITY; DENDRITIC CELLS.; NRF2;

ALLERGENS; AMINO ACIDS; ANTIOXIDANT RESPONSE ELEMENTS; CELL LINE; CYSTEINE; DENDRITIC CELLS; GENE EXPRESSION; HAPTENS; HEME OXYGENASE-1; HUMANS; MONOCYTES; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2;

EID: 84878514155     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft075     Document Type: Article

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