-
1
-
-
34250928307
-
Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system
-
In German
-
Ehringer H, Hornykiewicz O. Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system. Klin Wochenschr 1960;38:1236-1239. In German.
-
(1960)
Klin Wochenschr
, vol.38
, pp. 1236-1239
-
-
Ehringer, H.1
Hornykiewicz, O.2
-
2
-
-
73049129373
-
The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia
-
In German
-
Birkmayer W, Hornykiewicz O. The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia. Wien Klin Wochenschr 1961;73:787-788. In German.
-
(1961)
Wien Klin Wochenschr
, vol.73
, pp. 787-788
-
-
Birkmayer, W.1
Hornykiewicz, O.2
-
3
-
-
0020680904
-
Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston JW, Ballard P, Tetrud JW, Irwin I. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983;219:979-980.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
4
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997;276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
5
-
-
3543056130
-
Neurodegeneration and neuroprotection in Parkinson disease
-
Fahn S, Sulzer D. Neurodegeneration and neuroprotection in Parkinson disease. NeuroRx 2004;1:139-154.
-
(2004)
NeuroRx
, vol.1
, pp. 139-154
-
-
Fahn, S.1
Sulzer, D.2
-
6
-
-
3042793602
-
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging
-
Zecca L, Stroppolo A, Gatti A, et al. The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proc Natl Acad Sci USA 2004;101:9843-9848.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9843-9848
-
-
Zecca, L.1
Stroppolo, A.2
Gatti, A.3
-
7
-
-
12944305793
-
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles
-
Sulzer D, Bogulavsky J, Larsen KE, et al. Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proc Natl Acad Sci USA 2000;97:11869-11874.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11869-11874
-
-
Sulzer, D.1
Bogulavsky, J.2
Larsen, K.E.3
-
8
-
-
1942517416
-
Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: Human midbrain dopamine neurons
-
Liang CL, Nelson O, Yazdani U, Pasbakhsh P, German DC. Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons. J Comp Neurol 2004;473:97-106.
-
(2004)
J Comp Neurol
, vol.473
, pp. 97-106
-
-
Liang, C.L.1
Nelson, O.2
Yazdani, U.3
Pasbakhsh, P.4
German, D.C.5
-
9
-
-
0034024975
-
Interaction of human substantia nigra neuromelanin with lipids and peptides
-
Zecca L, Costi P, Mecacci C, Ito S, Terreni M, Sonnino S. Interaction of human substantia nigra neuromelanin with lipids and peptides. J Neurochem 2000;74:1758-1765.
-
(2000)
J Neurochem
, vol.74
, pp. 1758-1765
-
-
Zecca, L.1
Costi, P.2
Mecacci, C.3
Ito, S.4
Terreni, M.5
Sonnino, S.6
-
10
-
-
0033769320
-
Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins
-
Double KL, Zecca L, Costi P, et al. Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins. J Neurochem 2000;75:2583-2589.
-
(2000)
J Neurochem
, vol.75
, pp. 2583-2589
-
-
Double, K.L.1
Zecca, L.2
Costi, P.3
-
11
-
-
0042731682
-
The structure of neuromelanin as studied by chemical degradative methods
-
Wakamatsu K, Fujikawa K, Zucca FA, Zecca L, Ito S. The structure of neuromelanin as studied by chemical degradative methods. J Neurochem 2003;86:1015-1023.
-
(2003)
J Neurochem
, vol.86
, pp. 1015-1023
-
-
Wakamatsu, K.1
Fujikawa, K.2
Zucca, F.A.3
Zecca, L.4
Ito, S.5
-
14
-
-
0242285663
-
Neuromelanin of the substantia nigra: A neuronal black hole with protective and toxic characteristics
-
Zecca L, Zucca FA, Wilms H, Sulzer D. Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics. Trends Neurosci 2003;26:578-580.
-
(2003)
Trends Neurosci
, vol.26
, pp. 578-580
-
-
Zecca, L.1
Zucca, F.A.2
Wilms, H.3
Sulzer, D.4
-
15
-
-
0014541594
-
The histochemical relationship of neuromelanin and lipofuscin
-
Barden H. The histochemical relationship of neuromelanin and lipofuscin. J Neuropathol Exp Neurol 1969;28:419-441.
-
(1969)
J Neuropathol Exp Neurol
, vol.28
, pp. 419-441
-
-
Barden, H.1
-
16
-
-
0016242482
-
Lipoprotein pigments - Their relationship to ageing in the human nervous system. II. The melanin content of pigmented nerve cells
-
Mann DM, Yates PO. Lipoprotein pigments - their relationship to ageing in the human nervous system. II. The melanin content of pigmented nerve cells. Brain 1974;97:489-498.
-
(1974)
Brain
, vol.97
, pp. 489-498
-
-
Mann, D.M.1
Yates, P.O.2
-
17
-
-
0022622191
-
Nuclear configuration and neuronal types of the nucleus niger in the brain of the human adult
-
Braak H, Braak E. Nuclear configuration and neuronal types of the nucleus niger in the brain of the human adult. Hum Neurobiol 1986;5:71-82.
-
(1986)
Hum Neurobiol
, vol.5
, pp. 71-82
-
-
Braak, H.1
Braak, E.2
-
18
-
-
0028006428
-
Iron and other metals in neuromelanin, substantia nigra, and putamen of human brain
-
Zecca L, Pietra R, Goj C, Mecacci C, Radice D, Sabbioni E. Iron and other metals in neuromelanin, substantia nigra, and putamen of human brain. J Neurochem 1994;62:1097-1101.
-
(1994)
J Neurochem
, vol.62
, pp. 1097-1101
-
-
Zecca, L.1
Pietra, R.2
Goj, C.3
Mecacci, C.4
Radice, D.5
Sabbioni, E.6
-
19
-
-
0026666528
-
Iron-melanin complex in substantia nigra of parkinsonian brains: An x-ray microanalysis
-
Jellinger K, Kienzl E, Rumpelmair G, et al. Iron-melanin complex in substantia nigra of parkinsonian brains: an x-ray microanalysis. J Neurochem 1992;59:1168-1171.
-
(1992)
J Neurochem
, vol.59
, pp. 1168-1171
-
-
Jellinger, K.1
Kienzl, E.2
Rumpelmair, G.3
-
20
-
-
0026752050
-
Comparative techniques for determining cellular iron distribution in brain tissues
-
Perl DP, Good PF. Comparative techniques for determining cellular iron distribution in brain tissues. Ann Neurol 1992;32 (suppl) S76-81.
-
(1992)
Ann Neurol
, vol.32
, Issue.SUPPL.
-
-
Perl, D.P.1
Good, P.F.2
-
21
-
-
17044461766
-
Binding of iron to neuromelanin of human substantia nigra and synthetic melanin: An electron paramagnetic resonance spectroscopy study
-
Shima T, Sarna T, Swartz HM, Stroppolo A, Gerbasi R, Zecca L. Binding of iron to neuromelanin of human substantia nigra and synthetic melanin: an electron paramagnetic resonance spectroscopy study. Free Radic Biol Med 1997;23:110-119.
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 110-119
-
-
Shima, T.1
Sarna, T.2
Swartz, H.M.3
Stroppolo, A.4
Gerbasi, R.5
Zecca, L.6
-
22
-
-
0028999659
-
The effect of a synthetic neuromelanin on yield of free hydroxyl radicals generated in model systems
-
Zareba M, Bober A, Korytowski W, Zecca L, Sarna T. The effect of a synthetic neuromelanin on yield of free hydroxyl radicals generated in model systems. Biochim Biophys Acta 1995;1271:343-348.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 343-348
-
-
Zareba, M.1
Bober, A.2
Korytowski, W.3
Zecca, L.4
Sarna, T.5
-
23
-
-
0020308323
-
Parkinson's disease: A disorder due to nigral glutathione deficiency?
-
Perry TL, Godin DV, Hansen S. Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci Lett 1982;33:305-310.
-
(1982)
Neurosci Lett
, vol.33
, pp. 305-310
-
-
Perry, T.L.1
Godin, D.V.2
Hansen, S.3
-
24
-
-
0023791488
-
Regional distribution of ubiquinones and tocopherols in the mouse brain: Lowest content of ubiquinols in the substantia nigra
-
Fariello RG, Ghilardi O, Peschechera A, Ramacci MT, Angelucci L. Regional distribution of ubiquinones and tocopherols in the mouse brain: lowest content of ubiquinols in the substantia nigra. Neuropharmacology 1988;27:1077-1080.
-
(1988)
Neuropharmacology
, vol.27
, pp. 1077-1080
-
-
Fariello, R.G.1
Ghilardi, O.2
Peschechera, A.3
Ramacci, M.T.4
Angelucci, L.5
-
25
-
-
0022539310
-
Selectivity of the parkinsonian neurotoxin MPTP: Toxic metabolite MPP9+ binds to neuromelanin
-
D'Amato RJ, Lipman ZP, Snyder SH. Selectivity of the parkinsonian neurotoxin MPTP: toxic metabolite MPP9+ binds to neuromelanin. Science 1986;231:987-989.
-
(1986)
Science
, vol.231
, pp. 987-989
-
-
D'Amato, R.J.1
Lipman, Z.P.2
Snyder, S.H.3
-
26
-
-
0023823245
-
Autoradiography of [14C]paraquat or [14C]diquat in frogs and mice: Accumulation in neuromelanin
-
Lindquist NG, Larsson BS, Lyden-Sokolowski A. Autoradiography of [14C]paraquat or [14C]diquat in frogs and mice: accumulation in neuromelanin. Neurosci Lett 1988;93:1-6.
-
(1988)
Neurosci Lett
, vol.93
, pp. 1-6
-
-
Lindquist, N.G.1
Larsson, B.S.2
Lyden-Sokolowski, A.3
-
27
-
-
1442265714
-
Long-term retention of neurotoxic beta-carbolines in brain neuromelanin
-
Ostergren A, Annas A, Skog K, Lindquist NG, Brittebo EB. Long-term retention of neurotoxic beta-carbolines in brain neuromelanin. J Neural Transm 2004;111:141-157.
-
(2004)
J Neural Transm
, vol.111
, pp. 141-157
-
-
Ostergren, A.1
Annas, A.2
Skog, K.3
Lindquist, N.G.4
Brittebo, E.B.5
-
28
-
-
0018190446
-
Binding of dopaminergic drugs by the neuromelanin of the substantia nigra, synthetic melanins and melanin granules
-
Salazar M, Sokoloski TD, Patil PN. Binding of dopaminergic drugs by the neuromelanin of the substantia nigra, synthetic melanins and melanin granules. Fed Proc 1978;37:2403-2407.
-
(1978)
Fed Proc
, vol.37
, pp. 2403-2407
-
-
Salazar, M.1
Sokoloski, T.D.2
Patil, P.N.3
-
29
-
-
0037366093
-
Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: Implications for Parkinson's disease
-
Wilms H, Rosenstiel P, Sievers J, Deuschl G, Zecca L, Lucius R. Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. FASEB J 2003;17:500-502.
-
(2003)
FASEB J
, vol.17
, pp. 500-502
-
-
Wilms, H.1
Rosenstiel, P.2
Sievers, J.3
Deuschl, G.4
Zecca, L.5
Lucius, R.6
-
30
-
-
0037116582
-
The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease
-
Zecca L, Fariello R, Riederer P, Sulzer D, Gatti A, Tampellini D. The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease. FEBS Lett 2002;510:216-220.
-
(2002)
FEBS Lett
, vol.510
, pp. 216-220
-
-
Zecca, L.1
Fariello, R.2
Riederer, P.3
Sulzer, D.4
Gatti, A.5
Tampellini, D.6
-
32
-
-
0025964041
-
The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method
-
Pakkenberg B, Moller A, Gundersen HJ, Mouritzen Dam A, Pakkenberg H. The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method. J Neurol Neurosurg Psychiatry 1991;54:30-33.
-
(1991)
J Neurol Neurosurg Psychiatry
, vol.54
, pp. 30-33
-
-
Pakkenberg, B.1
Moller, A.2
Gundersen, H.J.3
Mouritzen Dam, A.4
Pakkenberg, H.5
-
33
-
-
0026638825
-
Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease
-
Gibb WR. Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease. Brain Res 1992;581:283-291.
-
(1992)
Brain Res
, vol.581
, pp. 283-291
-
-
Gibb, W.R.1
-
34
-
-
0031914408
-
Low numbers and no loss of melanized nigral neurons with increasing age in normal human brains from India
-
Muthane U, Yasha TC, Shankar SK. Low numbers and no loss of melanized nigral neurons with increasing age in normal human brains from India. Ann Neurol 1998;43:283-287.
-
(1998)
Ann Neurol
, vol.43
, pp. 283-287
-
-
Muthane, U.1
Yasha, T.C.2
Shankar, S.K.3
-
35
-
-
0025954066
-
Ageing and Parkinson's disease: Substantia nigra regional selectivity
-
Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991;114:2283-2301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
36
-
-
0026662141
-
Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content?
-
Kastner A, Hirsch EC, Lejeune O, Javoy-Agid F, Rascol O, Agid Y. Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content? J Neurochem 1992;59:1080-1089.
-
(1992)
J Neurochem
, vol.59
, pp. 1080-1089
-
-
Kastner, A.1
Hirsch, E.C.2
Lejeune, O.3
Javoy-Agid, F.4
Rascol, O.5
Agid, Y.6
-
37
-
-
0033959077
-
Preservation of midbrain catecholaminergic neurons in very old human subjects
-
Kubis N, Faucheux BA, Ransmayr G, et al. Preservation of midbrain catecholaminergic neurons in very old human subjects. Brain 2000;123:366-373.
-
(2000)
Brain
, vol.123
, pp. 366-373
-
-
Kubis, N.1
Faucheux, B.A.2
Ransmayr, G.3
-
38
-
-
15244339160
-
Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease
-
Fedorow H, Tribl F, Halliday G, Gerlach M, Riederer P, Double KL. Neuromelanin in human dopamine neurons: comparison with peripheral melanins and relevance to Parkinson's disease. Prog Neurobiol 2005;75:109-124.
-
(2005)
Prog Neurobiol
, vol.75
, pp. 109-124
-
-
Fedorow, H.1
Tribl, F.2
Halliday, G.3
Gerlach, M.4
Riederer, P.5
Double, K.L.6
-
39
-
-
9244242006
-
The neuromelanin of human substantia nigra: Physiological and pathogenic aspects
-
Zucca FA, Giaveri G, Gallorini M, et al. The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment Cell Res 2004;17:610-617.
-
(2004)
Pigment Cell Res
, vol.17
, pp. 610-617
-
-
Zucca, F.A.1
Giaveri, G.2
Gallorini, M.3
-
40
-
-
0025763177
-
Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease
-
Gibb WR, Lees AJ. Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease. J Neurol Neurosurg Psychiatry 1991;54:388-396.
-
(1991)
J Neurol Neurosurg Psychiatry
, vol.54
, pp. 388-396
-
-
Gibb, W.R.1
Lees, A.J.2
-
41
-
-
0020509931
-
Possible role of neuromelanin in the pathogenesis of Parkinson's disease
-
Mann DM, Yates PO. Possible role of neuromelanin in the pathogenesis of Parkinson's disease. Mech Ageing Dev 1983;21:193-203.
-
(1983)
Mech Ageing Dev
, vol.21
, pp. 193-203
-
-
Mann, D.M.1
Yates, P.O.2
-
42
-
-
27844547163
-
In vivo detection of iron and neuromelanin by transcranial sonography: A new approach for early detection of substantia nigra damage
-
[Epub ahead of print]
-
Zecca L, Berg D, Arzberger T, et al. In vivo detection of iron and neuromelanin by transcranial sonography: a new approach for early detection of substantia nigra damage. Mov Disord 2005; [Epub ahead of print]
-
(2005)
Mov Disord
-
-
Zecca, L.1
Berg, D.2
Arzberger, T.3
-
43
-
-
0032829070
-
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
-
Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 1999;46:598-605.
-
(1999)
Ann Neurol
, vol.46
, pp. 598-605
-
-
Langston, J.W.1
Forno, L.S.2
Tetrud, J.3
Reeves, A.G.4
Kaplan, J.A.5
Karluk, D.6
-
44
-
-
0024575008
-
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on ultrastructure of nigral neuromelanin in Macaca fascicularis
-
Levi AC, DeMattei M, Ravazzani R, Corvetti G, Golden GT, Fariello RG. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on ultrastructure of nigral neuromelanin in Macaca fascicularis. Neurosci Lett 1989;96:271-276.
-
(1989)
Neurosci Lett
, vol.96
, pp. 271-276
-
-
Levi, A.C.1
Demattei, M.2
Ravazzani, R.3
Corvetti, G.4
Golden, G.T.5
Fariello, R.G.6
-
45
-
-
8344265251
-
Iron, brain ageing and neurodegenerative disorders
-
Zecca L, Youdim MB, Riederer P, Connor JR, Crichton RR. Iron, brain ageing and neurodegenerative disorders. Nature Rev Neurosci 2004b;5:863-873.
-
(2004)
Nature Rev Neurosci
, vol.5
, pp. 863-873
-
-
Zecca, L.1
Youdim, M.B.2
Riederer, P.3
Connor, J.R.4
Crichton, R.R.5
-
46
-
-
7944227205
-
Neuromelanin inhibits enzymatic activity of 26S proteasome in human dopaminergic SH-SY5Y cells
-
Shamoto-Nagai M, Maruyama W, Akao Y, et al. Neuromelanin inhibits enzymatic activity of 26S proteasome in human dopaminergic SH-SY5Y cells. J Neural Transm 2004;111:1253-1265.
-
(2004)
J Neural Transm
, vol.111
, pp. 1253-1265
-
-
Shamoto-Nagai, M.1
Maruyama, W.2
Akao, Y.3
|