Protective effect of Kalanchoe pinnata pers. (Crassulaceae) on gentamicin-induced nephrotoxicity in rats

Indian Journal of Pharmacology

Volumn 39, Issue 4, 2007, Pages 201-205

  Harlalka, Gaurav ^a   Patil, Chandragauda ^a   Patil, Mahesh ^a  

^a R C PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

Author keywords

Antioxidant; Bryophyllum pinnata; Gentamicin; Nephrotoxicity

Indexed keywords

CREATININE; FREE RADICAL; GENTAMICIN; KALANCHOE PINNATA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CELL DEATH; CONTROLLED STUDY; CRASSULACEAE; CREATININE BLOOD LEVEL; CREATININE URINE LEVEL; DESQUAMATION; DRUG EFFECT; DRUG SCREENING; GLOMERULUS; HISTOPATHOLOGY; IN VITRO STUDY; INFLAMMATORY CELL; KALANCHOE PINNATA; KIDNEY BLOOD VESSEL; KIDNEY CELL; KIDNEY INJURY; KIDNEY TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; RENAL PROTECTION; UREA NITROGEN BLOOD LEVEL;

EID: 35548944434     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: 10.4103/0253-7613.36540     Document Type: Article

References (22)

1. Sastri BN. Kalanchoe pinnata. In: Thacker MS, Ram LS, Krishnan MS, Prashad B, Chopra RN, Santapau H, editors. The Wealth of India, A dictionary of Indian raw materials and industrial products, Raw Materials. CSIR: New Delhi; 2001. Vol. V: H-K, p. 315-6.
2. Ojewole JA. Antinociceptive, anti-inflammatory and antidiabetic effects of Bryophyllum pinnatum (Crassulaceae) leaf aqueous extract. J Ethnopharmacol 2005;99:13-9.
3. Maldonado PD, Barrera D, Rivero I, Mata R, Campos ON, Pando RH, et al. Antioxidant S-Allylcysteine prevents gentamicin-induced oxidative stress and renal damage. Free Radiac Biol Med 2003b;35:317-24.
4. Shirwaikar A, Issac D, Malini S. Effect of Aerva lanata on cisplatin and gentamicin models of acute renal failure. J Ethnopharmacol 2004;90:81-6.
5. Varma RK, Ahmad A, Kharole MU, Garg BD. Toxicologic studies on Kalanchoe integra: An indigenous plant: Acute toxicity study. Indian J Pharmacol 1979;11:301-5.
6. Varma RK, Garg BD, Ahmad A. Pharmacodynamic studies on Kalanchoe integra: An indigenous plant. Indian J Pharmacol 1986;18:78-83.
7. Azhar Alam MM, Javed K, Jafri MA. Effect of Rheum emodi (Revand Hindi) on renal functions in rats. J Ethnopharmacol 2005;96:121-5.
8. Murakami H, Yayama K, Chao J, Chao L. Atrial natriuretic peptide gene delivery attenuates gentamycin-induced nephrotoxicity in rats. Nephrol Dial Transplant 1999;14:1376-84.
9. Annie S, Rajagopal PL, Malini S. Effect of Cassia auriculata Linn Root extract on cisplatin and gentamicin-induced renal injury. Phytomedicine 2005;12:555-60.
10. Erdem A, Gondogan NU, Usubatan A, Kilinc K, Erdem SR, Kara A, et al. The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats. Nephrol Dial Transplant 2000;15:1175-82.
11. Ogeturk M, Kus I, Colakoglu N, Zararsiz I, Ilhan N, Sarsilmaz M. Caffeic acid phenethyl ester protects kidneys against carbon tetrachloride toxicity in rats. J Ethnopharmacol 2005;97:273-80.
12. Altarejos J, Salido S, Bonilla MP, Palomino PJ, Beek TA, Nogueras M, et al. Preliminary assay on the free radical scavenging activity of olive wood extracts. Fitoterapia 2005;76:348-51.
13. Gopinathan N, Srinivasan KK, Mathew JE. Free radical scavenging properties of the ethanol extract of Saccharum spontaneum. Indian Drugs 2004;41:633-5.
14. Badami S, Prakash O, Dongre SH, Suresh B. In vitro antioxidant properties of Solanum pseudocapsicum leaf extracts. Indian J Pharmacol 2005;37:251-2.
15. Shetgiri PP, D.Mello PM. Antioxidant activity of flavonoids: A comparative study. Indian Drugs 2003;40:567-9.
16. Scibior A, Zaporowska H, Ostrowski J, Banach A. Combined effect of vanadium (V) and chromium (III) on lipid peroxidation in liver and kidney of rats. Chem Biol Interact 2006;159:213-22.
17. Kimuya Y, Kubo M, Tani T, Arichi S, Okuda H. Studies on Scutellariae Radix IV: Effects on lipid peroxidation in rat liver. Chem Pharma Bull (Tokyo) 1981;29:2610-7.
18. Okhawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8.
19. Rastogi RP, Mehrotra BN. Kalanchoe pinnata. In: Rastogi RP, editor. Compendium of Indian Medicinal Plants, Vol. II. CDRI: Lucknow; 1993. p. 112.
20. Rastogi RP, Mehrotra BN. Kalanchoe pinnata. In: Rastogi RP, editor. Compendium of Indian Medicinal Plants, Vol. I. CDRI: Lucknow; 1991. p. 147.
21. Vickery HB, Wilson DG. Preparation of Potassium Dihydrogen L,(+)-Isocitrate from Bryophyllum calycinum leaves. J Biol Chem 1958;233:14-7.
22. Morales AI, Sanchez CV, Jerkic M, Santiago JM, Gonzalez PD, Barriocanal FP, et al. Effect of quercetin on metallothionein, nitric oxide synthases and cyclooxygenase-2 expression on experimental chronic cadmium nephrotoxicity in rats. Toxicol Appl Pharmacol 2006;210:128-35.