Identification of chromosomal copy number variations and novel candidate loci in hereditary nonpolyposis colorectal cancer with mismatch repair proficiency

Genomics

Volumn 102, Issue 1, 2013, Pages 27-34

  Chen, Weixiang ^a,b,c   Yuan, Lin ^a,b   Cai, Ying ^a,b   Chen, Xiaocheng ^a,b   Chi, Yayun ^a,b   Wei, Ping ^a,b   Zhou, Xiaoyan ^a,b   Shi, Daren ^a,b  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

^c Shanghai Gongli Hospital   (China)

Author keywords

Colorectal neoplasms, hereditary nonpolyposis; Copy number variation; CytoScan HD Array; Genome wide analysis

Indexed keywords

MICROSATELLITE DNA; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADULT; ARTICLE; CHROMOSOME ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE AMPLIFICATION; GENE LOCUS; GENE OVEREXPRESSION; GENETIC VARIABILITY; GENOTYPE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MISMATCH REPAIR; MOLECULAR DYNAMICS; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS;

CHROMOSOMES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA COPY NUMBER VARIATIONS; DNA MISMATCH REPAIR; HETEROZYGOTE; HUMANS; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS;

EID: 84878499329     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2013.02.003     Document Type: Article

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