Induction of the metabolic regulator txnip in fasting-induced and natural torpor

Endocrinology

Volumn 154, Issue 6, 2013, Pages 2081-2091

  Hand, Laura E ^a   Saer, Ben R C ^a   Hui, Simon T ^b   Jinnah, Hyder A ^c   Steinlechner, Stephan ^d   Loudon, Andrew S I ^a   Bechtold, David A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; G PROTEIN COUPLED RECEPTOR; THIOREDOXIN INTERACTING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSENSOR; BRAIN THIRD VENTRICLE; BROWN ADIPOSE TISSUE; COLD EXPOSURE; CONTROLLED STUDY; DIET RESTRICTION; ENERGY EXPENDITURE; ENERGY METABOLISM; EPENDYMA; GENE EXPRESSION PROFILING; HAMSTER; HYPOTHALAMUS; IN SITU HYBRIDIZATION; LIVER; MALE; METABOLIC RATE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TORPOR; WESTERN BLOTTING; WHITE ADIPOSE TISSUE;

ANIMALS; CARRIER PROTEINS; COLD TEMPERATURE; CRICETINAE; DEOXYGLUCOSE; FASTING; FEMALE; GENE EXPRESSION PROFILING; HIBERNATION; HYPOTHALAMUS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIOREDOXINS; TRANSCRIPTIONAL ACTIVATION;

EID: 84878460507     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-2051     Document Type: Article

References (45)

1. Bechtold DA, Sidibe A, Saer BR, et al. A role for the melatonin-related receptor GPR50 in leptin signaling, adaptive thermogenesis, and torpor. Curr Biol. 2012;22:70-77.
2. Dufourny L, Levasseur A, Migaud M, et al. GPR50 is the mammalian ortholog of Mel1c: evidence of rapid evolution in mammals. BMC Evol Biol. 2008;8:105.
3. Ivanova EA, Bechtold DA, Dupré SM, et al. Altered metabolism in the melatonin-related receptor (GPR50) knockout mouse. Am J Physiol Endocrinol Metab. 2008;294:E176-E182.
4. Grünewald E, Kinnell HL, Porteous DJ, Thomson PA. GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth. Mol Cell Neurosci. 2009;42:363-371.
5. Thomson PA, Wray NR, Thomson AM, et al. Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor. Mol Psychiatry. 2005;10:470-478. (Pubitemid 40646435)
6. Macintyre DJ, McGhee KA, Maclean AW, et al. Association of GPR50, an X-linked orphan G protein-coupled receptor, and affective disorder in an independent sample of the Scottish population. Neurosci Lett. 2010;475:169-173.
7. Delavest M, Even C, Benjemaa N, Poirier MF, Jockers R, Krebs MO. Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern. Eur Psychiatry. 2012;27:369-371.
8. Ruby NF. Paraventricular nucleus ablation disrupts daily torpor in Siberian hamsters. Brain Res Bull. 1995;37:193-198.
9. Ruby NF, Ibuka N, Barnes BM, Zucker I. Suprachiasmatic nuclei influence torpor and circadian temperature rhythms in hamsters. Am J Physiol. 1989;257:R210-R215.
10. Nestler JR. Relationships between respiratory quotient and metabolic rate during entry to and arousal from daily torpor in deer mice (Peromyscus maniculatus). Physiol Zool. 1990;63:504-515.
11. Heldmaier G, Klingenspor M, Werneyer M, Lampi BJ, Brooks SP, Storey KB. Metabolic adjustments during daily torpor in the Djungarian hamster. Am J Physiol. 1999;276:E896-E906. (Pubitemid 29249609)
12. Nestler JR. Metabolic substrate change during daily torpor in deer mice. Canad J Zool. 1991;69:322-327.
13. Dark J, Lewis DA, Zucker I. Hypoglycemia and torpor in Siberian hamsters. Am J Physiol. 1999;276:R776-R781. (Pubitemid 29157507)
14. Atgie C, Nibbelink M, Ambid L. Sympathoadrenal activity and hypoglycemia in the hibernating garden dormouse. Physiol Behav. 1990;48:783-787.
15. Brown JC, Gerson AR, Staples JF. Mitochondrial metabolism during daily torpor in the dwarf Siberian hamster: role of active regulated changes and passive thermal effects. Am J Physiol Regul Integr Comp Physiol. 2007;293:R1833-R1845. (Pubitemid 350085659)
16. Brown JC, Staples JF. Mitochondrial metabolism during fasting-induced daily torpor in mice. Biochim Biophys Acta. 2010;1797:476-486.
17. Nishiyama A, Matsui M, Iwata S, et al. Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression. J Biol Chem. 1999;274:21645-21650.
18. Sheth SS, Castellani LW, Chari S, et al. Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition. J Lipid Res. 2005;46:123-134. (Pubitemid 40066678)
19. Chutkow WA, Birkenfeld AL, Brown JD, et al. Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity. Diabetes. 2010;59:1424-1434.
20. Hui ST, Andres AM, Miller AK, et al. Txnip balances metabolic and growth signaling via PTEN disulfide reduction. Proc Natl Acad Sci USA. 2008;105:3921-3926. (Pubitemid 351723500)
21. Blouet C, Schwartz GJ. Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice. J Neurosci. 2011;31:6019-6027.
22. Barrett P, Ivanova E, Graham ES, et al. Photoperiodic regulation of cellular retinol binding protein, CRBP1 [corrected] and nestin in tanycytes of the third ventricle ependymal layer of the Siberian hamster. J Endocrinol. 2006;191:687-698. (Pubitemid 46210293)
23. Hooper M, Hardy K, Handyside A, Hunter S, Monk M. HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature. 1987;326:292-295. (Pubitemid 17053752)
24. Mathew TC. Regional analysis of the ependyma of the third ventricle of rat by light and electron microscopy. Anat Histol Embryol. 2008;37:9-18.
25. Rodríguez EM, Blázquez JL, Pastor FE, et al. Hypothalamic tanycytes: a key component of brain-endocrine interaction. Int Rev Cytol. 2005;247:89-164. (Pubitemid 41782012)
26. Dark J, Miller DR, Zucker I. Reduced glucose availability induces torpor in Siberian hamsters. Am J Physiol. 1994;267:R496-R501.
27. Swoap SJ, Gutilla MJ, Liles LC, Smith RO, Weinshenker D. The full expression of fasting-induced torpor requires β3-adrenergic receptor signaling. J Neurosci. 2006;26:241-245. (Pubitemid 43089537)
28. Oelkrug R, Heldmaier G, Meyer CW. Torpor patterns, arousal rates, and temporal organization of torpor entry in wildtype and UCP1-ablated mice. J Comp Physiol B. 2011;181:137-145.
29. Ruf T, Klingenspor M, Preis H, Heldmaier G. Daily torpor in the Djungarian hamster (Phodopus sungorus): interactions with food intake, activity, and social behaviour. J Comp Physiol B. 1991;160:609-615.
30. Blouet C, Liu SM, Jo YH, Chua S, Schwartz GJ. TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity. J Neurosci. 2012;32:9870-9877.
31. Schwartz C, Hampton M, Andrews MT. Seasonal and regional differences in gene expression in the brain of a hibernating mammal. PLoS One. 2013;8:e58427.
32. Kim SY, Suh HW, Chung JW, Yoon SR, Choi I. Diverse functions of VDUP1 in cell proliferation, differentiation, and diseases. Cell Mol Immunol. 2007;4:345-351.
33. Zhou J, Chng WJ. Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer. Mitochondrion. 2013;13(3):163-169.
34. Patwari P, Lee RT. An expanded family of arrestins regulate metabolism. Trends Endocrinol Metab. 2012;23:216-222.
35. Oka S, Liu W, Masutani H, et al. Impaired fatty acid utilization in thioredoxin binding protein-2 (TBP-2)-deficient mice: a unique animal model of Reye syndrome. FASEB J. 2006;20:121-123. (Pubitemid 43100487)
36. Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, Ayer DE. Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proc Natl Acad Sci USA. 2008;105:6912-6917. (Pubitemid 351754504)
37. Yu FX, Chai TF, He H, Hagen T, Luo Y. Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate. J Biol Chem. 2010;285:25822-25830.
38. Havula E, Hietakangas V. Glucose sensing by ChREBP/MondoAMlx transcription factors. Semin Cell Dev Biol. 2012;23:640-647.
39. Staples JF, Brown JC. Mitochondrial metabolism in hibernation and daily torpor: a review. J Comp Physiol B. 2008;178:811-827.
40. Nestler JR. Tissue-specific metabolism during normothermy and daily torpor in deer mice (Peromyscus maniculatus). J Exp Zool. 1992;261:406-413.
41. Ralser M, Wamelink MM, Struys EA, et al. A catabolic block does not sufficiently explainhow2-deoxy-D-glucose inhibits cell growth. Proc Natl Acad Sci USA. 2008;105:17807-17811.
42. Young P, Cawthorne MA, Levy AL, Wilson K. Reduced maximum capacity of glycolysis in brown adipose tissue of genetically obese, diabetic (db/db) mice and its restoration following treatment with a thermogenic β-adrenoceptor agonist. FEBS Lett. 1984;176:16-20. (Pubitemid 15203934)
43. Massa ML, Gagliardino JJ, Francini F. Liver glucokinase: an overview on the regulatory mechanisms of its activity. IUBMB Life. 2011;63:1-6.
44. Inokuma K, Ogura-Okamatsu Y, Toda C, Kimura K, Yamashita H, Saito M. Uncoupling protein 1 is necessary for norepinephrine-induced glucose utilization in brown adipose tissue. Diabetes. 2005;54:1385-1391. (Pubitemid 40586668)
45. Shimizu Y, Nikami H, Saito M. Sympathetic activation of glucose utilization in brown adipose tissue in rats. J Biochem. 1991;110:688-692.