-
1
-
-
49549116213
-
On the origins of arrestin and rhodopsin
-
Alvarez CE (2008) On the origins of arrestin and rhodopsin. BMC Evol Biol 8:222.
-
(2008)
BMC Evol Biol
, vol.8
, pp. 222
-
-
Alvarez, C.E.1
-
2
-
-
65949089009
-
The arrestin fold: Variations on a theme
-
Aubry L, Guetta D, Klein G (2009) The arrestin fold: variations on a theme. Curr Genomics 10:133-142.
-
(2009)
Curr Genomics
, vol.10
, pp. 133-142
-
-
Aubry, L.1
Guetta, D.2
Klein, G.3
-
3
-
-
27544450765
-
Divergence of melanocortin pathways in the control of food intake and energy expenditure
-
Balthasar N, Dalgaard LT, Lee CE, Yu J, Funahashi H, Williams T, Ferreira M, Tang V, McGovern RA, Kenny CD, Christiansen LM, Edelstein E, Choi B, Boss O, Aschkenasi C, Zhang CY, Mountjoy K, Kishi T, Elmquist JK, Lowell BB (2005) Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 123:493-505.
-
(2005)
Cell
, vol.123
, pp. 493-505
-
-
Balthasar, N.1
Dalgaard, L.T.2
Lee, C.E.3
Yu, J.4
Funahashi, H.5
Williams, T.6
Ferreira, M.7
Tang, V.8
McGovern, R.A.9
Kenny, C.D.10
Christiansen, L.M.11
Edelstein, E.12
Choi, B.13
Boss, O.14
Aschkenasi, C.15
Zhang, C.Y.16
Mountjoy, K.17
Kishi, T.18
Elmquist, J.K.19
Lowell, B.B.20
more..
-
4
-
-
79955754604
-
Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice
-
Blouet C, Schwartz GJ (2011) Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice. J Neurosci 31:6019-6027.
-
(2011)
J Neurosci
, vol.31
, pp. 6019-6027
-
-
Blouet, C.1
Schwartz, G.J.2
-
5
-
-
56449115916
-
Mediobasal hypothalamic p70 S6 kinase 1 modulates the control of energy homeostasis
-
Blouet C, Ono H, Schwartz GJ (2008) Mediobasal hypothalamic p70 S6 kinase 1 modulates the control of energy homeostasis. Cell Metab 8:459-467.
-
(2008)
Cell Metab
, vol.8
, pp. 459-467
-
-
Blouet, C.1
Ono, H.2
Schwartz, G.J.3
-
6
-
-
67649962153
-
Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit
-
Blouet C, Jo YH, Li X, Schwartz GJ (2009) Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit. J Neurosci 29:8302-8311.
-
(2009)
J Neurosci
, vol.29
, pp. 8302-8311
-
-
Blouet, C.1
Jo, Y.H.2
Li, X.3
Schwartz, G.J.4
-
7
-
-
18544385510
-
Positional cloning of the combined hyperlipidemia gene Hyplip1
-
Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, Lusis AJ (2002) Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat Genet 30:110-116.
-
(2002)
Nat Genet
, vol.30
, pp. 110-116
-
-
Bodnar, J.S.1
Chatterjee, A.2
Castellani, L.W.3
Ross, D.A.4
Ohmen, J.5
Cavalcoli, J.6
Wu, C.7
Dains, K.M.8
Catanese, J.9
Chu, M.10
Sheth, S.S.11
Charugundla, K.12
Demant, P.13
West, D.B.14
de Jong, P.15
Lusis, A.J.16
-
8
-
-
35548962415
-
Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation
-
Brito MN, Brito NA, Baro DJ, Song CK, Bartness TJ (2007) Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation. Endocrinology 148:5339-5347.
-
(2007)
Endocrinology
, vol.148
, pp. 5339-5347
-
-
Brito, M.N.1
Brito, N.A.2
Baro, D.J.3
Song, C.K.4
Bartness, T.J.5
-
9
-
-
42449110310
-
Thioredoxininteracting protein: A critical link between glucose toxicity and beta-cell apoptosis
-
Chen J, Saxena G, Mungrue IN, Lusis AJ, Shalev A (2008a) Thioredoxininteracting protein: a critical link between glucose toxicity and beta-cell apoptosis. Diabetes 57:938-944.
-
(2008)
Diabetes
, vol.57
, pp. 938-944
-
-
Chen, J.1
Saxena, G.2
Mungrue, I.N.3
Lusis, A.J.4
Shalev, A.5
-
10
-
-
54049102845
-
Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes
-
Chen J, Hui ST, Couto FM, Mungrue IN, Davis DB, Attie AD, Lusis AJ, Davis RA, Shalev A (2008b) Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes. FASEB J 22:3581-3594.
-
(2008)
FASEB J
, vol.22
, pp. 3581-3594
-
-
Chen, J.1
Hui, S.T.2
Couto, F.M.3
Mungrue, I.N.4
Davis, D.B.5
Attie, A.D.6
Lusis, A.J.7
Davis, R.A.8
Shalev, A.9
-
11
-
-
80051685491
-
Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability
-
Chutkow WA, Lee RT (2011) Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability. J Biol Chem 286:29139-29145.
-
(2011)
J Biol Chem
, vol.286
, pp. 29139-29145
-
-
Chutkow, W.A.1
Lee, R.T.2
-
12
-
-
38349151890
-
Thioredoxininteracting protein (Txnip) is a critical regulator of hepatic glucose production
-
Chutkow WA, Patwari P, Yoshioka J, Lee RT (2008) Thioredoxininteracting protein (Txnip) is a critical regulator of hepatic glucose production. J Biol Chem 283:2397-2406.
-
(2008)
J Biol Chem
, vol.283
, pp. 2397-2406
-
-
Chutkow, W.A.1
Patwari, P.2
Yoshioka, J.3
Lee, R.T.4
-
13
-
-
77953196716
-
Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity
-
Chutkow WA, Birkenfeld AL, Brown JD, Lee HY, Frederick DW, Yoshioka J, Patwari P, Kursawe R, Cushman SW, Plutzky J, Shulman GI, Samuel VT, Lee RT (2010) Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity. Diabetes 59:1424-1434.
-
(2010)
Diabetes
, vol.59
, pp. 1424-1434
-
-
Chutkow, W.A.1
Birkenfeld, A.L.2
Brown, J.D.3
Lee, H.Y.4
Frederick, D.W.5
Yoshioka, J.6
Patwari, P.7
Kursawe, R.8
Cushman, S.W.9
Plutzky, J.10
Shulman, G.I.11
Samuel, V.T.12
Lee, R.T.13
-
14
-
-
0032772960
-
The central melanocortin system and energy homeostasis
-
Cone RD (1999) The central melanocortin system and energy homeostasis. Trends Endocrinol Metab 10:211-216.
-
(1999)
Trends Endocrinol Metab
, vol.10
, pp. 211-216
-
-
Cone, R.D.1
-
15
-
-
58149391976
-
Monitoring FoxO1 localization in chemically identified neurons
-
Fukuda M, Jones JE, Olson D, Hill J, Lee CE, Gautron L, Choi M, Zigman JM, Lowell BB, Elmquist JK (2008) Monitoring FoxO1 localization in chemically identified neurons. J Neurosci 28:13640-13648.
-
(2008)
J Neurosci
, vol.28
, pp. 13640-13648
-
-
Fukuda, M.1
Jones, J.E.2
Olson, D.3
Hill, J.4
Lee, C.E.5
Gautron, L.6
Choi, M.7
Zigman, J.M.8
Lowell, B.B.9
Elmquist, J.K.10
-
16
-
-
0038043228
-
Ontogeny of the hypothalamic neuropeptide Y system
-
Grove KL, Smith MS (2003) Ontogeny of the hypothalamic neuropeptide Y system. Physiol Behav 79:47-63.
-
(2003)
Physiol Behav
, vol.79
, pp. 47-63
-
-
Grove, K.L.1
Smith, M.S.2
-
18
-
-
0032942045
-
Characterization of the neuroanatomical distribution of agoutirelated protein immunoreactivity in the rhesus monkey and the rat
-
Haskell-Luevano C, Chen P, Li C, Chang K, Smith MS, Cameron JL, Cone RD (1999) Characterization of the neuroanatomical distribution of agoutirelated protein immunoreactivity in the rhesus monkey and the rat. Endocrinology 140:1408-1415.
-
(1999)
Endocrinology
, vol.140
, pp. 1408-1415
-
-
Haskell-Luevano, C.1
Chen, P.2
Li, C.3
Chang, K.4
Smith, M.S.5
Cameron, J.L.6
Cone, R.D.7
-
20
-
-
41649100341
-
Txnip balances metabolic and growth signaling via PTEN disulfide reduction
-
Hui ST, Andres AM, Miller AK, Spann NJ, Potter DW, Post NM, Chen AZ, Sachithanantham S, Jung DY, Kim JK, Davis RA (2008) Txnip balances metabolic and growth signaling via PTEN disulfide reduction. Proc Natl Acad Sci U S A 105:3921-3926.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3921-3926
-
-
Hui, S.T.1
Andres, A.M.2
Miller, A.K.3
Spann, N.J.4
Potter, D.W.5
Post, N.M.6
Chen, A.Z.7
Sachithanantham, S.8
Jung, D.Y.9
Kim, J.K.10
Davis, R.A.11
-
21
-
-
2642557131
-
Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals
-
Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA (2004) Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. J Biol Chem 279:24387-24393.
-
(2004)
J Biol Chem
, vol.279
, pp. 24387-24393
-
-
Hui, T.Y.1
Sheth, S.S.2
Diffley, J.M.3
Potter, D.W.4
Lusis, A.J.5
Attie, A.D.6
Davis, R.A.7
-
22
-
-
0029762615
-
Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus
-
Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Morgan PJ, Trayhurn P (1996) Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus. J Neuroendocrinol 8:733-735.
-
(1996)
J Neuroendocrinol
, vol.8
, pp. 733-735
-
-
Mercer, J.G.1
Hoggard, N.2
Williams, L.M.3
Lawrence, C.B.4
Hannah, L.T.5
Morgan, P.J.6
Trayhurn, P.7
-
23
-
-
39749142664
-
Activation of Stat3 signaling in AgRP neurons promotes locomotor activity
-
Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC (2008) Activation of Stat3 signaling in AgRP neurons promotes locomotor activity. Cell Metab 7:236-248.
-
(2008)
Cell Metab
, vol.7
, pp. 236-248
-
-
Mesaros, A.1
Koralov, S.B.2
Rother, E.3
Wunderlich, F.T.4
Ernst, M.B.5
Barsh, G.S.6
Rajewsky, K.7
Brüning, J.C.8
-
24
-
-
0033618398
-
Identification of thioredoxin-binding protein-2/vitamin D(3) upregulated protein 1 as a negative regulator of thioredoxin function and expression
-
Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, Yodoi J (1999) Identification of thioredoxin-binding protein-2/vitamin D(3) upregulated protein 1 as a negative regulator of thioredoxin function and expression. J Biol Chem 274:21645-21650.
-
(1999)
J Biol Chem
, vol.274
, pp. 21645-21650
-
-
Nishiyama, A.1
Matsui, M.2
Iwata, S.3
Hirota, K.4
Masutani, H.5
Nakamura, H.6
Takagi, Y.7
Sono, H.8
Gon, Y.9
Yodoi, J.10
-
25
-
-
36048955043
-
The central melanocortin system directly controls peripheral lipid metabolism
-
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, et al. (2007) The central melanocortin system directly controls peripheral lipid metabolism. J Clin Invest 117:3475-3488.
-
(2007)
J Clin Invest
, vol.117
, pp. 3475-3488
-
-
Nogueiras, R.1
Wiedmer, P.2
Perez-Tilve, D.3
Veyrat-Durebex, C.4
Keogh, J.M.5
Sutton, G.M.6
Pfluger, P.T.7
Castaneda, T.R.8
Neschen, S.9
Hofmann, S.M.10
Howles, P.N.11
Morgan, D.A.12
Benoit, S.C.13
Szanto, I.14
Schrott, B.15
Schürmann, A.16
Joost, H.G.17
Hammond, C.18
Hui, D.Y.19
Woods, S.C.20
more..
-
26
-
-
34249660144
-
TXNIP regulates peripheral glucose metabolism in humans
-
Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, et al. (2007) TXNIP regulates peripheral glucose metabolism in humans. PLoS Med 4:e158.
-
(2007)
PLoS Med
, vol.4
-
-
Parikh, H.1
Carlsson, E.2
Chutkow, W.A.3
Johansson, L.E.4
Storgaard, H.5
Poulsen, P.6
Saxena, R.7
Ladd, C.8
Schulze, P.C.9
Mazzini, M.J.10
Jensen, C.B.11
Krook, A.12
Björnholm, M.13
Tornqvist, H.14
Zierath, J.R.15
Ridderstråle, M.16
Altshuler, D.17
Lee, R.T.18
Vaag, A.19
Groop, L.C.20
more..
-
27
-
-
33746787216
-
The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange
-
Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, Lee RT (2006) The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange. J Biol Chem 281:21884-21891.
-
(2006)
J Biol Chem
, vol.281
, pp. 21884-21891
-
-
Patwari, P.1
Higgins, L.J.2
Chutkow, W.A.3
Yoshioka, J.4
Lee, R.T.5
-
28
-
-
69949139700
-
Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins
-
Patwari P, Chutkow WA, Cummings K, Verstraeten VL, Lammerding J, Schreiter ER, Lee RT (2009) Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins. J Biol Chem 284:24996-25003.
-
(2009)
J Biol Chem
, vol.284
, pp. 24996-25003
-
-
Patwari, P.1
Chutkow, W.A.2
Cummings, K.3
Verstraeten, V.L.4
Lammerding, J.5
Schreiter, E.R.6
Lee, R.T.7
-
29
-
-
80455143723
-
The arrestin domain-containing 3 protein regulates body mass and energy expenditure
-
Patwari P, Emilsson V, Schadt EE, Chutkow WA, Lee S, Marsili A, Zhang Y, Dobrin R, Cohen DE, Larsen PR, Zavacki AM, Fong LG, Young SG, Lee RT (2011) The arrestin domain-containing 3 protein regulates body mass and energy expenditure. Cell Metab 14:671-683.
-
(2011)
Cell Metab
, vol.14
, pp. 671-683
-
-
Patwari, P.1
Emilsson, V.2
Schadt, E.E.3
Chutkow, W.A.4
Lee, S.5
Marsili, A.6
Zhang, Y.7
Dobrin, R.8
Cohen, D.E.9
Larsen, P.R.10
Zavacki, A.M.11
Fong, L.G.12
Young, S.G.13
Lee, R.T.14
-
30
-
-
0038168650
-
Leptininduced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II
-
Scarpace PJ, Matheny M, Zolotukhin S, Tümer N, Zhang Y (2003) Leptininduced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II. Neuropharmacology 45:211-219.
-
(2003)
Neuropharmacology
, vol.45
, pp. 211-219
-
-
Scarpace, P.J.1
Matheny, M.2
Zolotukhin, S.3
Tümer, N.4
Zhang, Y.5
-
31
-
-
53849116110
-
Lack of TXNIP protects beta-cells against glucotoxicity
-
Shalev A (2008) Lack of TXNIP protects beta-cells against glucotoxicity. Biochem Soc Trans 36:963-965.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 963-965
-
-
Shalev, A.1
-
32
-
-
19944426522
-
Thioredoxininteracting protein deficiency disrupts the fasting-feeding metabolic transition
-
Sheth SS, Castellani LW, Chari S, Wagg C, Thipphavong CK, Bodnar JS, Tontonoz P, Attie AD, Lopaschuk GD, Lusis AJ (2005) Thioredoxininteracting protein deficiency disrupts the fasting-feeding metabolic transition. J Lipid Res 46:123-134.
-
(2005)
J Lipid Res
, vol.46
, pp. 123-134
-
-
Sheth, S.S.1
Castellani, L.W.2
Chari, S.3
Wagg, C.4
Thipphavong, C.K.5
Bodnar, J.S.6
Tontonoz, P.7
Attie, A.D.8
Lopaschuk, G.D.9
Lusis, A.J.10
-
33
-
-
77954407546
-
Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues
-
Shrestha YB, Vaughan CH, Smith BJ Jr, Song CK, Baro DJ, Bartness TJ (2010) Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues. Am J Physiol Regul Integr Comp Physiol 299:R140-R149.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.299
-
-
Shrestha, Y.B.1
Vaughan, C.H.2
Smith Jr., B.J.3
Song, C.K.4
Baro, D.J.5
Bartness, T.J.6
-
34
-
-
27144523482
-
Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue
-
Song CK, Jackson RM, Harris RB, Richard D, Bartness TJ (2005) Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue. Am J Physiol Regul Integr Comp Physiol 289:R1467-R1476.
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.289
-
-
Song, C.K.1
Jackson, R.M.2
Harris, R.B.3
Richard, D.4
Bartness, T.J.5
-
35
-
-
41549111593
-
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion
-
van de Wall E, Leshan R, Xu AW, Balthasar N, Coppari R, Liu SM, Jo YH, MacKenzie RG, Allison DB, Dun NJ, Elmquist J, Lowell BB, Barsh GS, de Luca C, Myers MG Jr, Schwartz GJ, Chua SC Jr (2008) Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology 149:1773-1785.
-
(2008)
Endocrinology
, vol.149
, pp. 1773-1785
-
-
van de Wall, E.1
Leshan, R.2
Xu, A.W.3
Balthasar, N.4
Coppari, R.5
Liu, S.M.6
Jo, Y.H.7
Mackenzie, R.G.8
Allison, D.B.9
Dun, N.J.10
Elmquist, J.11
Lowell, B.B.12
Barsh, G.S.13
de Luca, C.14
Myers Jr., M.G.15
Schwartz, G.J.16
Chua Jr., S.C.17
-
36
-
-
37349082873
-
Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload
-
Yoshioka J, Imahashi K, Gabel SA, Chutkow WA, Burds AA, Gannon J, Schulze PC, MacGillivray C, London RE, Murphy E, Lee RT (2007) Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload. Circ Res 101:1328-1338.
-
(2007)
Circ Res
, vol.101
, pp. 1328-1338
-
-
Yoshioka, J.1
Imahashi, K.2
Gabel, S.A.3
Chutkow, W.A.4
Burds, A.A.5
Gannon, J.6
Schulze, P.C.7
Macgillivray, C.8
London, R.E.9
Murphy, E.10
Lee, R.T.11
|