Regulation of SIRT1 in Vascular Smooth Muscle Cells from Streptozotocin-Diabetic Rats

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Toniolo, Alice ^a   Warden, Erica Alessia ^a   Nassi, Alberto ^a   Cignarella, Andrea ^a   Bolego, Chiara ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRESS; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; GLUCOSE BLOOD LEVEL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; NONHUMAN; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN LOCALIZATION; RAT; STREPTOZOCIN DIABETES; UPREGULATION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DOWN-REGULATION; ESTRADIOL; ESTROGENS; GLUCOSE; HUMANS; IMMUNOHISTOCHEMISTRY; LEUKOCYTES, MONONUCLEAR; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, SPRAGUE-DAWLEY; SIRTUIN 1; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MAMMALIA; RATTUS;

EID: 84878443848     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065666     Document Type: Article

References (36)

1. Ungvari Z, Kaley G, de Cabo R, Sonntag WE, Csiszar A, (2010) Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci 65: 1028-1041.
2. Li L, Zhang HN, Chen HZ, Gao P, Zhu LH, et al. (2011) SIRT1 acts as a modulator of neointima formation following vascular injury in mice. Circ Res 108: 1180-1189.
3. Guarente L, (2011) Franklin H. Epstein Lecture: Sirtuins, aging, and medicine. N Engl J Med 364: 2235-2244.
4. Orimo M, Minamino T, Miyauchi H, Tateno K, Okada S, et al. (2009) Protective role of SIRT1 in diabetic vascular dysfunction. Arterioscler Thromb Vasc Biol 29: 889-894.
5. Banks AS, Kon N, Knight C, Matsumoto M, Gutiérrez-Juárez R, et al. (2008) SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 8: 333-341.
6. Miyazaki R, Ichiki T, Hashimoto T, Inanaga K, Imayama I, et al. (2008) SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 28: 1263-1269.
7. Tajbakhsh N, Sokoya EM, (2012) Regulation of cerebral vascular function by sirtuin 1. Microcirculation 19: 336-342.
8. Feige JN, Auwerx J, (2008) Transcriptional targets of sirtuins in the coordination of mammalian physiology. Curr Opin Cell Biol 20: 303-309.
9. Kwon HS, Ott M, (2008) The ups and downs of SIRT1. Trends Biochem Sci 33: 517-525.
10. Fernandes CA, Fievez L, Neyrinck AM, Delzenne NM, Bureau F, et al. (2012) Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. Biochem Biophys Res Commun 420: 857-861.
11. Moore RL, Dai Y, Faller DV, (2012) Sirtuin 1 (SIRT1) and steroid hormone receptor activity in cancer. J Endocrinol 213: 37-48.
12. de Kreutzenberg SV, Ceolotto G, Papparella I, Bortoluzzi A, Semplicini A, et al. (2010) Downregulation of the longevity-associated protein sirtuin 1 in insulin resistance and metabolic syndrome: potential biochemical mechanisms. Diabetes 59: 1006-1015.
13. Wei M, Ong L, Smith MT, Ross FB, Schmid K, et al. (2003) The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes. Heart Lung Circ 12: 44-50.
14. Zancan V, Santagati S, Bolego C, Vegeto E, Maggi A, et al. (1999) 17β-estradiol decreases nitric oxide synthase II synthesis in vascular smooth muscle cells. Endocrinology 140: 2004-2009.
15. Maggi A, Cignarella A, Brusadelli A, Bolego C, Pinna C, et al. (2003) Diabetes undermines estrogen control of inducible nitric oxide synthase function in rat aortic smooth muscle cells through overexpression of estrogen receptor-β. Circulation 108: 211-217.
16. Idel S, Ellinghaus P, Wolfrum C, Nofer JR, Gloerich J, et al. (2002) Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells. J Biol Chem 277: 49319-49325.
17. Zhang HN, Li L, Gao P, Chen HZ, Zhang R, et al. (2010) Involvement of the p65/RelA subunit of NF-κB in TNF-α-induced SIRT1 expression in vascular smooth muscle cells. Biochem Biophys Res Commun 397: 569-575.
18. Ruderman NB, Xu XJ, Nelson L, Cacicedo JM, Saha AK, et al. (2010) AMPK and SIRT1: a long-standing partnership? Am J Physiol Endocrinol Metab 298: E751-E760.
19. Schulz E, Anter E, Zou MH, Keaney JF Jr, (2005) Estradiol-mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase. Circulation 111: 3473-3480.
20. Ning J, Xi G, Clemmons DR, (2011) Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells. Endocrinology 152: 3143-3154.
21. Yao H, Rahman I, (2012) Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. Biochem Pharmacol 84: 1332-1339.
22. Wu A, Ying Z, Gomez-Pinilla F, (2006) Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex. Eur J Neurosci 23: 2573-2580.
23. Caito S, Rajendrasozhan S, Cook S, Chung S, Yao H, et al. (2010) SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress. FASEB J 24: 3145-3159.
24. Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, et al. (2007) Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100: 1512-1521.
25. Shen Z, Ajmo JM, Rogers CQ, Liang X, Le L, et al. (2009) Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines. Am J Physiol Gastrointest Liver Physiol 296: G1047-G1053.
26. Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, et al. (2010) SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. Am J Physiol Endocrinol Metab 298: E419-E428.
27. Imai S, Armstrong CM, Kaeberlein M, Guarente L, (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403: 795-800.
28. Braidy N, Guillemin G, Mansour H, Chan-Ling T, Poljak A, et al. (2011) Age related changes in NAD+ metabolism, oxidative stress and Sirt1 Activity in Wistar rats. PLOS ONE 6: e19194.
29. Ortmann J, Veit M, Zingg S, Di Santo S, Traupe T, et al. (2011) Estrogen receptor-α but not-β or GPER inhibits high glucose-induced human VSMC proliferation: potential role of ROS and ERK. J Clin Endocrinol Metab 96: 220-228.
30. Elangovan S, Ramachandran S, Venkatesan N, Ananth S, Gnana-Prakasam JP, et al. (2011) SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer. Cancer Res 71: 6654-6664.
31. Sastre-Serra J, Nadal-Serrano M, Gabriel Pons D, Valle A, Garau I, García-Bonafé M, Oliver J, Roca P. (2013) The oxidative stress in breast tumors of postmenopausal women is ERα/ERβ ratio dependent. Free Radic Biol Med doi:pii: S0891-5849(13)00099-3. 10.1016/j.
32. Kim MY, Woo EM, Chong YT, Homenko DR, Kraus WL, (2006) Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. Mol Endocrinol 20: 1479-1493.
33. Prossnitz ER, Arterburn JB, Smith HO, Oprea TI, Sklar LA, et al. (2008) Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annu Rev Physiol 70: 165-190.
34. Gurd BJ, Yoshida Y, Lally J, Holloway GP, Bonen A, (2009) The deacetylase enzyme SIRT1 is not associated with oxidative capacity in rat heart and skeletal muscle and its overexpression reduces mitochondrial biogenesis. J Physiol 587: 1817-1828.
35. Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, et al. (2008) SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One 3: e1759.
36. Lempiäinen J, Finckenberg P, Levijoki J, Mervaala E, (2012) AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney. Br J Pharmacol 166: 1905-1915.