-
1
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, et al. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41: 1088-1093.
-
(2009)
Nat Genet
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
-
2
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, Campion D, Sleegers K, et al. (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41: 1094-1099.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
-
3
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, et al. (2010) Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 303: 1832-1840.
-
(2010)
JAMA
, vol.303
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
DeStefano, A.L.4
Gudnason, V.5
-
4
-
-
77955463899
-
Replication of CLU, CR1, and PICALM associations with alzheimer disease
-
Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, et al. (2010) Replication of CLU, CR1, and PICALM associations with alzheimer disease. Arch Neurol 67: 961-964.
-
(2010)
Arch Neurol
, vol.67
, pp. 961-964
-
-
Carrasquillo, M.M.1
Belbin, O.2
Hunter, T.A.3
Ma, L.4
Bisceglio, G.D.5
-
5
-
-
79959219655
-
Replication of BIN1 Association with Alzheimer's Disease and Evaluation of Genetic Interactions
-
Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, et al. (2011) Replication of BIN1 Association with Alzheimer's Disease and Evaluation of Genetic Interactions. J Alzheimers Dis.
-
(2011)
J Alzheimers Dis
-
-
Carrasquillo, M.M.1
Belbin, O.2
Hunter, T.A.3
Ma, L.4
Bisceglio, G.D.5
-
6
-
-
79952089521
-
Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease
-
Hu X, Pickering E, Liu YC, Hall S, Fournier H, et al. (2011) Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. PLoS One 6: e16616.
-
(2011)
PLoS One
, vol.6
-
-
Hu, X.1
Pickering, E.2
Liu, Y.C.3
Hall, S.4
Fournier, H.5
-
7
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
-
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, et al. (2011) Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 43: 436-441.
-
(2011)
Nat Genet
, vol.43
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
Wang, L.S.4
Vardarajan, B.N.5
-
8
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, et al. (2011) Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 43: 429-435.
-
(2011)
Nat Genet
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
Gerrish, A.4
Lambert, J.C.5
-
9
-
-
79952500081
-
Identification of Novel Loci for Alzheimer Disease and Replication of CLU, PICALM, and BIN1 in Caribbean Hispanic Individuals
-
Lee JH, Cheng R, Barral S, Reitz C, Medrano M, et al. (2010) Identification of Novel Loci for Alzheimer Disease and Replication of CLU, PICALM, and BIN1 in Caribbean Hispanic Individuals. Arch Neurol.
-
(2010)
Arch Neurol
-
-
Lee, J.H.1
Cheng, R.2
Barral, S.3
Reitz, C.4
Medrano, M.5
-
10
-
-
77957909886
-
Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes
-
Jun G, Naj AC, Beecham GW, Wang LS, Buros J, et al. (2010) Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes. Arch Neurol.
-
(2010)
Arch Neurol
-
-
Jun, G.1
Naj, A.C.2
Beecham, G.W.3
Wang, L.S.4
Buros, J.5
-
12
-
-
34249745769
-
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
-
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, et al. (2007) GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron 54: 713-720.
-
(2007)
Neuron
, vol.54
, pp. 713-720
-
-
Reiman, E.M.1
Webster, J.A.2
Myers, A.J.3
Hardy, J.4
Dunckley, T.5
-
13
-
-
77957730965
-
Genome-wide association studies in Alzheimer's disease
-
Bertram L, Tanzi RE, (2009) Genome-wide association studies in Alzheimer's disease. Hum Mol Genet 18: R137-145.
-
(2009)
Hum Mol Genet
, vol.18
-
-
Bertram, L.1
Tanzi, R.E.2
-
14
-
-
84855808864
-
Examination of the current top candidate genes for AD in a genome-wide association study
-
Feulner TM, Laws SM, Friedrich P, Wagenpfeil S, Wurst SH, et al. (2009) Examination of the current top candidate genes for AD in a genome-wide association study. Mol Psychiatry.
-
(2009)
Mol Psychiatry
-
-
Feulner, T.M.1
Laws, S.M.2
Friedrich, P.3
Wagenpfeil, S.4
Wurst, S.H.5
-
15
-
-
67349256894
-
The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis
-
Ikram MA, Liu F, Oostra BA, Hofman A, van Duijn CM, et al. (2009) The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis. Biol Psychiatry 65: 995-999.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 995-999
-
-
Ikram, M.A.1
Liu, F.2
Oostra, B.A.3
Hofman, A.4
van Duijn, C.M.5
-
16
-
-
65549098785
-
Implication of GAB2 gene polymorphism in Italian patients with Alzheimer's disease
-
Nacmias B, Tedde A, Bagnoli S, Cellini E, Guarnieri BM, et al. (2009) Implication of GAB2 gene polymorphism in Italian patients with Alzheimer's disease. J Alzheimers Dis 16: 513-515.
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 513-515
-
-
Nacmias, B.1
Tedde, A.2
Bagnoli, S.3
Cellini, E.4
Guarnieri, B.M.5
-
17
-
-
64049116471
-
Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia
-
Sleegers K, Bettens K, Brouwers N, Engelborghs S, van Miegroet H, et al. (2009) Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia. Hum Mutat 30: E338-344.
-
(2009)
Hum Mutat
, vol.30
-
-
Sleegers, K.1
Bettens, K.2
Brouwers, N.3
Engelborghs, S.4
van Miegroet, H.5
-
18
-
-
40849102705
-
Association study of the GAB2 gene with the risk of developing Alzheimer's disease
-
Chapuis J, Hannequin D, Pasquier F, Bentham P, Brice A, et al. (2008) Association study of the GAB2 gene with the risk of developing Alzheimer's disease. Neurobiol Dis 30: 103-106.
-
(2008)
Neurobiol Dis
, vol.30
, pp. 103-106
-
-
Chapuis, J.1
Hannequin, D.2
Pasquier, F.3
Bentham, P.4
Brice, A.5
-
19
-
-
38349038412
-
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
-
Li H, Wetten S, Li L, St Jean PL, Upmanyu R, et al. (2008) Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol 65: 45-53.
-
(2008)
Arch Neurol
, vol.65
, pp. 45-53
-
-
Li, H.1
Wetten, S.2
Li, L.3
St Jean, P.L.4
Upmanyu, R.5
-
20
-
-
63249096555
-
GAB2 gene does not modify the risk of Alzheimer's disease in Spanish APOE 4 carriers
-
Ramirez-Lorca R, Boada M, Saez ME, Hernandez I, Mauleon A, et al. (2009) GAB2 gene does not modify the risk of Alzheimer's disease in Spanish APOE 4 carriers. J Nutr Health Aging 13: 214-219.
-
(2009)
J Nutr Health Aging
, vol.13
, pp. 214-219
-
-
Ramirez-Lorca, R.1
Boada, M.2
Saez, M.E.3
Hernandez, I.4
Mauleon, A.5
-
21
-
-
67349266214
-
GAB2 is not associated with late-onset Alzheimer's disease in Japanese
-
Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, et al. (2009) GAB2 is not associated with late-onset Alzheimer's disease in Japanese. Eur J Hum Genet 17: 682-686.
-
(2009)
Eur J Hum Genet
, vol.17
, pp. 682-686
-
-
Miyashita, A.1
Arai, H.2
Asada, T.3
Imagawa, M.4
Shoji, M.5
-
22
-
-
77955887300
-
GAB2 is not associated with late-onset Alzheimer's disease in Chinese Han
-
Lin K, Tang M, Han H, Guo Y, Lin Y, et al. (2010) GAB2 is not associated with late-onset Alzheimer's disease in Chinese Han. Neurol Sci 31: 277-281.
-
(2010)
Neurol Sci
, vol.31
, pp. 277-281
-
-
Lin, K.1
Tang, M.2
Han, H.3
Guo, Y.4
Lin, Y.5
-
23
-
-
79953752763
-
Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease
-
Belbin O, Carrasquillo MM, Crump M, Culley OJ, Hunter TA, et al. (2011) Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease. Hum Genet 129: 273-282.
-
(2011)
Hum Genet
, vol.129
, pp. 273-282
-
-
Belbin, O.1
Carrasquillo, M.M.2
Crump, M.3
Culley, O.J.4
Hunter, T.A.5
-
24
-
-
34548805282
-
A genome-wide association study of global gene expression
-
Dixon AL, Liang L, Moffatt MF, Chen W, Heath S, et al. (2007) A genome-wide association study of global gene expression. Nat Genet 39: 1202-1207.
-
(2007)
Nat Genet
, vol.39
, pp. 1202-1207
-
-
Dixon, A.L.1
Liang, L.2
Moffatt, M.F.3
Chen, W.4
Heath, S.5
-
25
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, et al. (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
-
26
-
-
0036155283
-
Score tests for association between traits and haplotypes when linkage phase is ambiguous
-
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA, (2002) Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70: 425-434.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 425-434
-
-
Schaid, D.J.1
Rowland, C.M.2
Tines, D.E.3
Jacobson, R.M.4
Poland, G.A.5
-
27
-
-
3242891068
-
VISTA: computational tools for comparative genomics
-
Frazer KA, Pachter L, Poliakov A, Rubin EM, Dubchak I, (2004) VISTA: computational tools for comparative genomics. Nucleic Acids Res 32: W273-279.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Frazer, K.A.1
Pachter, L.2
Poliakov, A.3
Rubin, E.M.4
Dubchak, I.5
-
28
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
-
29
-
-
27644439141
-
Efficiency and power in genetic association studies
-
de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, et al. (2005) Efficiency and power in genetic association studies. Nat Genet 37: 1217-1223.
-
(2005)
Nat Genet
, vol.37
, pp. 1217-1223
-
-
de Bakker, P.I.1
Yelensky, R.2
Pe'er, I.3
Gabriel, S.B.4
Daly, M.J.5
-
30
-
-
0034667783
-
Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling
-
Pratt JC, Igras VE, Maeda H, Baksh S, Gelfand EW, et al. (2000) Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling. J Immunol 165: 4158-4163.
-
(2000)
J Immunol
, vol.165
, pp. 4158-4163
-
-
Pratt, J.C.1
Igras, V.E.2
Maeda, H.3
Baksh, S.4
Gelfand, E.W.5
-
31
-
-
3343005434
-
PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations
-
Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, et al. (2004) PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. EMBO J 23: 2586-2596.
-
(2004)
EMBO J
, vol.23
, pp. 2586-2596
-
-
Baki, L.1
Shioi, J.2
Wen, P.3
Shao, Z.4
Schwarzman, A.5
-
32
-
-
77649295213
-
Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease
-
Carrasquillo MM, Belbin O, Zou F, Allen M, Ertekin-Taner N, et al. (2010) Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease. PLoS One 5: e8764.
-
(2010)
PLoS One
, vol.5
-
-
Carrasquillo, M.M.1
Belbin, O.2
Zou, F.3
Allen, M.4
Ertekin-Taner, N.5
-
33
-
-
76649095363
-
Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease
-
Zou F, Carrasquillo MM, Pankratz VS, Belbin O, Morgan K, et al. (2010) Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease. Neurology 74: 480-486.
-
(2010)
Neurology
, vol.74
, pp. 480-486
-
-
Zou, F.1
Carrasquillo, M.M.2
Pankratz, V.S.3
Belbin, O.4
Morgan, K.5
-
34
-
-
60549101350
-
GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results
-
Schjeide BM, Hooli B, Parkinson M, Hogan MF, DiVito J, et al. (2009) GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. Arch Neurol 66: 250-254.
-
(2009)
Arch Neurol
, vol.66
, pp. 250-254
-
-
Schjeide, B.M.1
Hooli, B.2
Parkinson, M.3
Hogan, M.F.4
DiVito, J.5
|