Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake

Journal of Controlled Release

Volumn 170, Issue 1, 2013, Pages 83-91

  Verdurmen, Wouter P R ^a   Wallbrecher, Rike ^a   Schmidt, Samuel ^a   Eilander, Jos ^a   Bovee Geurts, Petra ^a   Fanghänel, Susanne ^b   Bürck, Jochen ^b   Wadhwani, Parvesh ^b   Ulrich, Anne S ^b   Brock, Roland ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Cell penetrating peptide; Drug delivery; Endocytosis; Heparan sulfate proteoglycan; Metabolic labeling; Stereochemistry

Indexed keywords

AMINO ACIDS; ARGININE; CELL MEMBRANES; CHAINS; CYTOLOGY; DRUG DELIVERY; METABOLISM; MOLECULAR BIOLOGY; PEPTIDES; STEREOCHEMISTRY; SULFUR COMPOUNDS;

CELL PENETRATING PEPTIDES (CPPS); CELL-PENETRATING PEPTIDE; ENDOCYTOSIS; ENZYMATIC CLEAVAGE; HEPARAN SULFATE PROTEOGLYCANS; METABOLIC LABELING; PROTEOGLYCANS; TIME-LAPSE MICROSCOPY;

CELLS;

ARGININE; CELL PENETRATING PEPTIDE; HEPARAN SULFATE; PROTEOHEPARAN SULFATE; SIALIC ACID DERIVATIVE; TRANSPORTAN 10; UNCLASSIFIED DRUG;

ARTICLE; CELL AGGREGATION; CELL MEMBRANE; CELL SURFACE; CHEMICAL INTERACTION; CLICK CHEMISTRY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG UPTAKE; ENZYME METABOLISM; GLYCOCALYX; HUMAN; HUMAN CELL; MICROSCOPY; PRIORITY JOURNAL; STEREOCHEMISTRY; STIMULATION; THERMODYNAMICS;

EID: 84878406436     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.05.001     Document Type: Article

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