-
1
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter P, Ron D, (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334: 1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
2
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
Fu S, Yang L, Li P, Hofmann O, Dicker L, et al. (2011) Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 473: 528-531.
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
Hofmann, O.4
Dicker, L.5
-
3
-
-
52749091008
-
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
-
Boden G, Duan X, Homko C, Molina EJ, Song W, et al. (2008) Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals. Diabetes 57: 2438-2444.
-
(2008)
Diabetes
, vol.57
, pp. 2438-2444
-
-
Boden, G.1
Duan, X.2
Homko, C.3
Molina, E.J.4
Song, W.5
-
4
-
-
62749178966
-
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
-
Gregor MF, Yang L, Fabbrini E, Mohammed BS, Eagon JC, et al. (2009) Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes 58: 693-700.
-
(2009)
Diabetes
, vol.58
, pp. 693-700
-
-
Gregor, M.F.1
Yang, L.2
Fabbrini, E.3
Mohammed, B.S.4
Eagon, J.C.5
-
5
-
-
57349110829
-
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects
-
Sharma NK, Das SK, Mondal AK, Hackney OG, Chu WS, et al. (2008) Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects. J Clin Endocrinol Metab 93: 4532-4541.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4532-4541
-
-
Sharma, N.K.1
Das, S.K.2
Mondal, A.K.3
Hackney, O.G.4
Chu, W.S.5
-
6
-
-
79955750296
-
Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo
-
Horl G, Wagner A, Cole LK, Malli R, Reicher H, et al. (2011) Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo. J Biol Chem 286: 17338-17350.
-
(2011)
J Biol Chem
, vol.286
, pp. 17338-17350
-
-
Horl, G.1
Wagner, A.2
Cole, L.K.3
Malli, R.4
Reicher, H.5
-
7
-
-
77954575279
-
Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity
-
Jacobs RL, Zhao Y, Koonen DP, Sletten T, Su B, et al. (2010) Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity. J Biol Chem 285: 22403-22413.
-
(2010)
J Biol Chem
, vol.285
, pp. 22403-22413
-
-
Jacobs, R.L.1
Zhao, Y.2
Koonen, D.P.3
Sletten, T.4
Su, B.5
-
8
-
-
84864829883
-
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice
-
Singh RK, Fullerton MD, Vine D, Bakovic M, (2012) Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice. J Lipid Res 53: 1811-1822.
-
(2012)
J Lipid Res
, vol.53
, pp. 1811-1822
-
-
Singh, R.K.1
Fullerton, M.D.2
Vine, D.3
Bakovic, M.4
-
9
-
-
79951705812
-
Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects
-
Sharma NK, Langberg KA, Mondal AK, Elbein SC, Das SK, (2011) Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects. J Clin Endocrinol Metab 96: E394-E403.
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Sharma, N.K.1
Langberg, K.A.2
Mondal, A.K.3
Elbein, S.C.4
Das, S.K.5
-
10
-
-
84859157638
-
Phosphatidylcholine biosynthesis and lipoprotein metabolism
-
Cole LK, Vance JE, Vance DE, (2012) Phosphatidylcholine biosynthesis and lipoprotein metabolism. Biochim Biophys Acta 1821: 754-761.
-
(2012)
Biochim Biophys Acta
, vol.1821
, pp. 754-761
-
-
Cole, L.K.1
Vance, J.E.2
Vance, D.E.3
-
11
-
-
79961232942
-
An integrative genomics approach identifies activation of thioredoxin/thioredoxin reductase-1-mediated oxidative stress defense pathway and inhibition of angiogenesis in obese nondiabetic human subjects
-
Das SK, Sharma NK, Hasstedt SJ, Mondal AK, Ma L, et al. (2011) An integrative genomics approach identifies activation of thioredoxin/thioredoxin reductase-1-mediated oxidative stress defense pathway and inhibition of angiogenesis in obese nondiabetic human subjects. J Clin Endocrinol Metab 96: E1308-E1313.
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Das, S.K.1
Sharma, N.K.2
Hasstedt, S.J.3
Mondal, A.K.4
Ma, L.5
-
12
-
-
78049349396
-
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
-
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, et al. (2010) Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 42: 949-960.
-
(2010)
Nat Genet
, vol.42
, pp. 949-960
-
-
Heid, I.M.1
Jackson, A.U.2
Randall, J.C.3
Winkler, T.W.4
Qi, L.5
-
13
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, et al. (2010) Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 42: 937-948.
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
-
14
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, et al. (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 42: 105-116.
-
(2010)
Nat Genet
, vol.42
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
-
15
-
-
75749091912
-
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
-
Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, et al. (2010) Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 42: 142-148.
-
(2010)
Nat Genet
, vol.42
, pp. 142-148
-
-
Saxena, R.1
Hivert, M.F.2
Langenberg, C.3
Tanaka, T.4
Pankow, J.S.5
-
16
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS
-
Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, et al. (2010) Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet 6: e1000888.
-
(2010)
PLoS Genet
, vol.6
-
-
Nicolae, D.L.1
Gamazon, E.2
Zhang, W.3
Duan, S.4
Dolan, M.E.5
-
17
-
-
13444269543
-
Haploview: analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ, (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
18
-
-
0347624611
-
MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test
-
Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, et al. (2003) MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther 5: 1003-1015.
-
(2003)
Diabetes Technol Ther
, vol.5
, pp. 1003-1015
-
-
Boston, R.C.1
Stefanovski, D.2
Moate, P.J.3
Sumner, A.E.4
Watanabe, R.M.5
-
19
-
-
34447131039
-
Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent
-
Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, et al. (2007) Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia 50: 1621-1630.
-
(2007)
Diabetologia
, vol.50
, pp. 1621-1630
-
-
Elbein, S.C.1
Chu, W.S.2
Das, S.K.3
Yao-Borengasser, A.4
Hasstedt, S.J.5
-
20
-
-
84873199254
-
Physiological roles of phosphatidylethanolamine N-methyltransferase
-
Vance DE, (2013) Physiological roles of phosphatidylethanolamine N-methyltransferase. Biochim Biophys Acta 1831: 626-632.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 626-632
-
-
Vance, D.E.1
-
21
-
-
77954162542
-
Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes
-
Naukkarinen J, Surakka I, Pietilainen KH, Rissanen A, Salomaa V, et al. (2010) Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. PLoS Genet 6: e1000976.
-
(2010)
PLoS Genet
, vol.6
-
-
Naukkarinen, J.1
Surakka, I.2
Pietilainen, K.H.3
Rissanen, A.4
Salomaa, V.5
-
22
-
-
76749084749
-
Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus
-
Parikh H, Lyssenko V, Groop LC, (2009) Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus. BMC Med Genomics 2: 72.
-
(2009)
BMC Med Genomics
, vol.2
, pp. 72
-
-
Parikh, H.1
Lyssenko, V.2
Groop, L.C.3
-
23
-
-
79955470774
-
A better index of body adiposity
-
Bergman RN, Stefanovski D, Buchanan TA, Sumner AE, Reynolds JC, et al. (2011) A better index of body adiposity. Obesity (Silver Spring) 19: 1083-1089.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1083-1089
-
-
Bergman, R.N.1
Stefanovski, D.2
Buchanan, T.A.3
Sumner, A.E.4
Reynolds, J.C.5
|