Notch signalling in cardiovasculogenesis: Insight into their role in early cardiovascular development

Molecular Biology Reports

Volumn 40, Issue 5, 2013, Pages 3537-3547

  Saravanakumar, Marimuthu ^a   Devaraj, Halagowder ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

CVD; DAPT; Notch signalling; Tbx2; VEGF

Indexed keywords

DIMETHYL SULFOXIDE; ESTER DERIVATIVE; NOTCH RECEPTOR; TRANSCRIPTION FACTOR GATA 4; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREEDING; CARDIOVASCULAR DEVELOPMENT; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; FEMALE; GATA4 GENE; HEART DEVELOPMENT; HEART VENTRICLE SEPTUM; HEY1 GENE; HISTOLOGY; IMMUNOBLOTTING; IMMUNOLOCALIZATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPE; SIGNAL TRANSDUCTION; STEM CELL; WILD TYPE;

ANIMALS; ARTERIES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARDIOVASCULAR SYSTEM; FEMALE; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART SEPTAL DEFECTS, VENTRICULAR; MALE; MICE; PREGNANCY; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

MUS;

EID: 84878390011     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2427-9     Document Type: Article

References (33)

1. Pierpont ME, Basson CT, Benson DW Jr, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL (2007) American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young. Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation 115:3015-3038
2. Srivastava D (2003) Building a heart: implications for congenital heart disease. J Nucl Cardiol 10:63-70
3. Li D, Parks SB, Kushner JD, Nauman D, Burgess D, Ludwigsen S, Partain J, Nixon RR, Allen CN, Irwin RP, Jakobs PM, Litt M, Hershberger RE (2006) Mutations of presenilin genes in dilated cardiomyopathy and heart failure. Am J Hum Genet 79:1030-1039
4. McDaniell R, Warthen DM, Sanchez-Lara PA, Pai A, Krantz ID, Piccoli DA, Spinner NB (2006) NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signalling pathway. Am J Hum Genet 79:169-173
5. Eldadah ZA, Hamosh A, Biery NJ, Montgomery RA, Duke M, Elkins R, Dietz HC (2001) Familial tetralogy of fallot caused by mutation in the JAGGED1 gene Hum. Mol Genet 10:163-169
6. Duarte A, Hirashima M, Benedito R, Trindade A, Diniz P, Bekman E, Costa L, Henrique D, Rossant J (2004) Dosage-sensitive requirement for mouse DLL4 in artery development. Genes Dev 18:2474-2478
7. McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T (2001) Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development 128:491-502
8. Krebs LT, Xue Y, Norton CR, Shutter JR, Maguire M, Sundberg JP, Gallahan D, Closson V, Kitajewski J, Callahan R, Smith GH, Stark KL, Gridley T (2000) Notch signalling is essential for vascular morphogenesis in mice. Genes Dev 14:1343-1352
9. Bray SJ (2006) Notch signalling: a simple pathway becomes complex. Nature Rev Mol Cell Biol 7:678-689
10. Shiojima I, Komuro I, Inazawa J, Nakahori Y, Matsushita I, Abe T, Nagai R, Yazaki Y (1995) Assignment of cardiac homeobox gene CSX to human chromosome 5q34. Genomics 27:204-206
11. Iso T, Kedes L, Hamamori Y (2003) HES and HERP families: multiple effectors of the Notch signalling pathway. J Cell Physiol 194:237-255
12. Fischer A, Gessler M (2007) Delta-Notch - and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res 35:4583-4596
13. Harvey RP (1996) NK-2 homeobox genes and heart development. Dev Biol 178:203-216
14. Benson DW, Silberbach GM, Kavanaugh-McHugh A, Cottrill C, Zhang Y, Riggs S, Smalls O, Johnson MC, Watson MS, Seidman JG, Seidman CE, Plowden J, Kugler JD (1999) Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways. J Clin Invest 104:1567-1573
15. Heikinheimo M, Scandrett JM, Wilson DB (1994) Localization of transcription factor GATA4 to regions of the mouse embryo involved in cardiac development. Dev Biol 164:361-373
16. Charron F, Nemer M (1999) GATA transcription factors and cardiac development. Semin Cell Dev Biol 10:85-91
17. Christoffels VM, Hoogaars WMH, Tessari A, Clout DEW, Moorman AFM, Campione M (2004) T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Dev Dyn 229:763-770
18. Harrelson Z, Kelly RG, Goldin SN, Gibson-Brown JJ, Bollag RJ, Silver LM, Papaioannou VE (2004) Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development 131:5041-5052
19. Habets PEMH, Moorman AFM, Clout DEW, van Roon MA, Lingbeek M, Lohuizen M, Campione M, Christoffels VM (2002) Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev 16:1234-1246
20. Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ (2000) Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Dev Biol 228:95-105
21. Ya J, Markman MWM, Wagenaar GTM, Blommaart PB, Moorman AFM, Lamers WH (1997) Expression of the smooth-muscle proteins α-smooth-muscle actin and calponin, and of the intermediate filament protein desmin are parameters of cardiomyocyte maturation in the prenatal rat heart. Anat Rec 249:495-505
22. Deborah LR, Robert JS (1988) Sequential activation of ot-actin genes during avian cardiogenesis: vascular smooth muscle t-actin gene transcripts mark the onset of cardiomyocyte differentiation. J Cell Biol 107:2575-2586
23. Suk-Won J, Cam P (2009) The opening act: vasculogenesis and the origins of circulation. Arterioscler Thromb Vasc Biol 29:623-629
24. Zhang X, Gaspard JP, Chung DC (2001) Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. Cancer Res 61:6050-6054
25. Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E (2010) The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signalling. Dev Cell 18:938-949
26. Pandey S, Parvez S, Ansari RA, Ali M, Kaur M, Hayat F, Ahmad F, Raisuddin S (2008) Effects of exposure to multiple trace metals on biochemical, histological and ultrastructural features of gills of a freshwater fish Channa punctata. Bloch Chem Biol Int 174:183-192
27. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
28. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265-275
29. Wang HU, Chen ZF, Anderson DJ (1998) Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93:741-753
30. Krebs LT, Shutter JR, Tanigaki K, Honjo T, Stark KL, Gridley T (2004) Haplo insufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev 18:2469-2473
31. Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D (2005) Mutations in NOTCH1 cause aortic valve disease. Nature 437(7056):270-274
32. Gale NW, Yancopoulos GD (1999) Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes & Dev 13:1055-1066
33. Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z (1999) Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13:9-22