Amelioration of cadmium-induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and α-tocopherol in rats

Journal of Food Science

Volumn 75, Issue 7, 2010, Pages

  Prabu, S Milton ^a   Shagirtha, K ^a   Renugadevi, J ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

tocopherol; Cadmium; Lipids; Lipoproteins; Quercetin; Rats

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; CADMIUM CHLORIDE; GLUTATHIONE; QUERCETIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL; ARTICLE; BLOOD; CADMIUM POISONING; CARDIOVASCULAR DISEASE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DYSLIPIDEMIA; LIPID PEROXIDATION; LIVER; MALE; METABOLISM; OXIDATIVE STRESS; PATHOPHYSIOLOGY; POLLUTANT; RANDOMIZATION; RAT; RISK FACTOR; WISTAR RAT;

ALPHA-TOCOPHEROL; ANIMALS; ANTIOXIDANTS; CADMIUM CHLORIDE; CADMIUM POISONING; CARDIOVASCULAR DISEASES; DYSLIPIDEMIAS; ENVIRONMENTAL POLLUTANTS; GLUTATHIONE; LIPID PEROXIDATION; LIVER; MALE; OXIDATIVE STRESS; QUERCETIN; RANDOM ALLOCATION; RATS; RATS, WISTAR; RISK FACTORS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 77957116879     PISSN: 00221147     EISSN: 17503841     Source Type: Journal    
DOI: 10.1111/j.1750-3841.2010.01757.x     Document Type: Article

References (74)

1. Belyaeva EA, Korotkov SM. Mechanism of primary Cd2+-induced rat liver mitochondria dysfunction: discrete modes of Cd2+ action on calcium and thiol-dependent domains. Toxicol Appl Pharmacol 2003, 192:56-68.
2. Borges LP, Brandão R, Godoi B, Nogueira CW, Zeni G. Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats. Chem Biol Inter 2008, 171:15-25.
3. Burnstein M, Scholnic MR, Mortin R. Rapid method of isolation of lipoprotein from human serum by precipitation of polyanion. J Lipid Res 1970, 11:583-7.
4. Calderoni AM, Oliveros L, Jahn G, Anton R, Luco J, Gimenez MS. Alterations in the lipid content of pituitary gland and serum prolactin and growth hormone in cadmium treated rats. Biometals 2005, 18:213-20.
5. Chen JW, Zhu ZQ, Hu TX, Zhu TY. The structure-activity relationship of natural flavonoids in hydroxyl radical scavenging effects. Acta Pharmacol Sin 2002, 23:667-72.
6. Chen CY, Milbury PE, Lapsley K, Blumberg JB. Flavoniods from almond skins are bioavailable and act synergistically with vitamins C and E to enhance hamster and human LDL resistance to oxidation. J Nutr 2005, 135:1366-73.
7. Chen Y, Li X, Zhao B, Zheng R, Xin W. Superoxide and hydroxyl radical scavenging activities of rutin and other natural products studied by ESR. Biophys Acta 1989, 5:253-60.
8. Cheung WY. Calmodulin: its potential role in cells proliferation and heavy metal toxicity. Fed Proc 1984, 43:2995-8.
9. Choi JS, Chung HY, Kang SS. The structure-activity relationship of flavonoids as scavengers of peroxynitrite. Phytother Res 2002, 16:232-5.
10. Cox DA, Cohen ML. Effects of oxidized low density lipoproteins on vascular contraction and relaxation: clinical and pharmacological implications in atherosclerosis. Pharmacol Rev 1996, 48:3-9.
11. Doroshow JH. Effect of anthrocycline antibiotics on oxygen radical formation in rat heart. Cancer Res 1983, 43:460-72.
12. Duncan BD. Multiple range test for correlated and heteroscedastic means. Biometrics 1957, 13:359-64.
13. Durate J, Vizcaino FP, Utrilla P, Jimenez J, Tamarago J, Zarzuelo A. Vasodilatory effects of flavonoids in rat aortic smooth muscles; structure-activity relationships. J Pharmacol 1993, 24:857-62.
14. El-Demerdash M, Yousef MI, Kedwany FS, Bhagdadi HH. Cadmium induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene. Food Chem Toxicol 2004, 42:1563-71.
15. Ellman GL. Tissue sulphydryl groups. Arch Biochem Biophys 1959, 82:70-7.
16. Ercal N, Gurer-Orhan H, Aykin-Burns N. Toxic metals and oxidative stress. Part I: mechanisms involved in metal-induced oxidative damage. Curr Top Med Chem 2001, 1:529-39.
17. Esterbauer H, Gebicki J, Puhl H, Jurgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med 1992, 13:341-90.
18. Falholt K, Falholt W, Lund B. An easy colorimetric method for routine determination of free fatty acids in plasma. Clin Chim Acta 1973, 46:105-11.
19. Ferry DR, Smith A, Malkhandi J, Fyfe DW, DeTakats PG, Anderson D. Phase I clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res 1996, 2:659-68.
20. Fiske CH, Subbarow Y. The colorimetric determination of phosphorus. J Biol Chem 1925, 66:375-400.
21. Folch J, Lees M, Solane SGH. A simple method for isolation and purification of total lipids from animal tissues. J Biol Chem 1957, 226:497-509.
22. Fossati P, Lorenzo P. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 1982, 28:2077-80.
23. Gey KFP, Puska P, Jordan UK. Moser, Inverse correlation between plasma vitamin E and mortality from ischaemic heart disease in cross-cultural epidemiology. Am J Clin Nutr 1991, 53(Suppl.):S326-34.
24. Han JC, Park SY, Hah BG, Choi GH, Kim YK, Kwon TH. Cadmium induces impaired glucose tolerance in rat by down regulating GLUT4 expression in adipocytes. Arch Biochem Biophys 2003, 413:213-20.
25. Harstad EB, Klaassen CD. Acute cadmium exposure enhances AP-1 DNA binding and induces cytokines expression and heat shock protein 70 in HepG2 cells. Toxicology 2004, 197:213-28.
26. Hitz J, Sterinmetz J, Surt G. LCAT-reference values and effects of xenobiotics. Clin Chim Acta 1983, 133:85-96.
27. Houtman JWP. Prolonged low-level cadmium intake and atherosclerosis. Science of the Total Environment 1993, 138:31-6.
28. Huesca-Gomez C, Franco M, Luc G, Montano LF, Masso F, Posadas- Romero C. Chronic hypothyroidism induces abnormal structure of high-density lipoproteins and impaired kinetics of apolipoprotein A-I in the rat. Metabolism 2002, 51:443-50.
29. Janik A, Gawlik M. Behavior of selected indicators of lipid metabolism in kidney and liver of rats continuously exposed to effects of cadmium. Folia Med Cracov 1993, 34:211-7.
30. Jarup L, Berglund M, Elinder CG. Health effects of Cd exposure: a review of the literature and a risk estimate. Scand J Work Environ Health 1998, 24:1-51.
31. Jemai H, Messaoudi I, Chaouch A, Kerkeni A. Protective effect of zinc supplementation on blood antioxidant defense system in rats exposed to cadmium. J Trace Elem Med Biol 2007, 21:269-73.
32. Jiang ZY, Hunt JV, Wolff SD. Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein. Anal Biochem 1992, 202:384-9.
33. Jurczuk M, Brzóska MM, Moniuszko-Jakoniuk J, Galażyn-Sidorczuk M, Kulikowska-Karpinska E. Antioxidant enzymes activity and lipid peroxidation in liver and kidney of rats exposed to cadmium and ethanol. Food Chem Toxicol 2004, 42:429-38.
34. Kantola T, Kivisto KT, Neuvonen PJ. Grapefruit juice greatly increases serum concentration of lovastatin and lovastatin acid. Clin Pharmacol Ther 1998, 63:397-402.
35. Kayama F, Yoshida T, Elwell MR, Luster MI. Role of tumor necrosis factor-α in cadmium induced hepatotoxicity. Toxicol Appl Pharmacol 1995, 131:224-34.
36. Kojima M, Masui T, Nemoto K, Degawa M. Lead nitrate induced development of hypercholesterolemia in rats: sterol independent gene regulation of hepatic enzymes responsible for cholesterol homeostasis. Toxicol Lett 2004, 154:35-44.
37. Larregle EV, Varas SM, Olivreos LB, Martinez LD, Antón RE, Marchevsky E, Gimenez MS. Lipid metabolism in liver of rat exposed to cadmium. Food Chem Toxicol 2008, 46:1786-92.
38. Levine RL, Garland D, Oliver CN, Amic A, Climent I, Lenz AG. Determination of carbonyl content in oxidatively modified proteins. Method Enzymol 1999, 186:464-78.
39. Mallika V, Goswami B, Rajappa M. Atherosclerosis pathophysiology and the role of novel risk factors: a clinic biochemical perspective. Angiology 2007, 58:513-22.
40. Martin MJ, Motilva V, Lastra ADL. Quercetin and naringenin: effects on ulcer formation and gastric secretion in rats. Phytother Res 1993, 7:150-3.
41. Maxfield FR, Tabas I. Role of cholesterol and lipid organization in disease. Nature 2005, 438:612-21.
42. Mayes PA, Botham KM. Lipid transport and storage. Harper's illustrated biochemistry 2003, 205-18. Murray RK, Granner DKMayes PARodwell VW. ditors, 26th ed., New York, McGraw-Hill Companies Inc, p
43. Meister A. New aspects of glutathione biochemistry and transport selective alterations of glutathione metabolism. Nutr Rev 1984, 42:397-410.
44. Memon RA, Grunfeld C, Moser AH, Feingold KR. Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triacylglycerol metabolism in mice. Endocrinology 1993, 132:2246-53.
45. Moon YJ, Wang X, Morris ME. Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol In Vitro 2006, 20:187-210.
46. Moniuszko-Jakoniuk J, Rogalska J, Brzóska MM. The influence of cadmium on selected parameters of lipid metabolism in rat serum, aorta and heart. Pol J Environ Stud 1999, 8:200-4.
47. Morales AI, Vincente-Sanchez C, Santoval JM. Protective effect of quercetin on experimental chronic cadmium nephrotoxicity in rats is based on its antioxidant properties. Food Chem Toxicol 2006, 44:2092-100.
48. Murugavel P, Pari L. Diallyl tetrasulfide protects cadmium-induced alterations in lipids and plasma lipoproteins in rats. Nutr Res 2007, 27:356-61.
49. Nachiappan V, Curtiss D, Corkey BE, Kilpatrick L. Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes. Synergy among TNF, IL-6 and IL-1. Shock 1994, 1:123-9.
50. Nemmiche S, Chabane-Sari D, Guiraud P. Role of α-tocopherol in cadmium induced oxidative stress in Wistar rat's blood, liver and brain. Chem Biol Inter 2007, 170:221-30.
51. Niehiaus WG, Samuelson B. Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid per-oxidation. Eur J Biochem 1968, 6:126-30.
52. Paier B, Hagmuller K, Noli MI, Gonzalez Pondal M, Stiegler C, Zaninovich AA. Changes induced by cadmium administration on thyroxine deiodination and sulfhydryl groups in rat liver. J Endocrinol 1993, 138:219-24.
53. Petrovich DR, Finkelstein S, Waring AJ, Farber JL. Liver ischemia increases the molecular order of microsomal membranes by increasing the cholesterol to phospholipid ratio. J Biol Chem 1984, 259:13217-23.
54. Philipp B, Shapiro DJ. Improved methods for the assay and activation of 3-hydroxy-3-methyl glutaryl coenzyme A reductase. J Lipid Res 1970, 20:588-93.
55. Ramirez DC, Gimenez MS. Lipid modification in mouse peritoneal macrophages after chronic cadmium exposure. Toxicology 2002, 172:1-12.
56. Rao KS, Recknagel RO. Early onset of lipid peroxidation in rat liver after carbon tetrachloride administration. Exp Mol Pathol 1968, 9:271-8.
57. Renugadevi J, Milton Prabu S. Quercetin protects against oxidative stress-related renal dysfunction by cadmium in rats. Exp Toxicol Pathol 2009, 10.1016/j-etp.2009.06.006, DOI
58. Rogalska J, Brzoska MM, Roszczenko A, Jakoniuk JM. Enhanced zinc consumption prevents cadmium induced alterations in lipid metabolism in male rats. Chem Biol Inter 2009, 177:142-52.
59. Russo M, Palumbo R, Tedesco I, Mazzarella G, Russo P, Iacomino G, Russo GL. Quercetin and anti-CD95 (Fas/APO1) enhance apoptosis in HPB-cell line. FEBS Lett 1999, 462:322-8.
60. Satarug S, Baker JR, Urbenjapol S, Haswell-Elkins M, Reilly PE, Williams DJ, Moore MR. A global perspective on cadmium pollution and toxicity in non-occupationally exposed population. Toxicol Lett 2003, 137:65-83.
61. Sesso HD, Gaziano JM, Liu S, Buring JE. Flavonoid intake and the risk of cardiovascular disease in women. Am J Clin Nutr 2003, 77:1400-8.
62. Sestili P, Guidarelli A, Dacha M, Cantoni O. Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. Free Radic Biol Med 1998, 25:196-200.
63. Skoczynska A. High density lipoprotein cholesterol level in rats poisoned with cadmium. Med Pr 2001, 52:355-9.
64. Soleas GJ, Grass L, Josphy PD, Goldberg DM, Diamandis EP. A comparison of the anti-carcinogenic properties of four red wine polyphenols. Clin Biochem 2002, 35:119-24.
65. Stohs SJ, Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 1995, 18:321-36.
66. Stohs SJ, Bagchi D, Hassoun E, Bagchi M. Oxidative mechanisms in the toxicity of chromium and cadmium ions. J Environ Pathol Toxicol Oncol 2000, 19:201-13.
67. Subramanyan G, Bhaskar M, Govindappa S. The role of cadmium in induction of atherosclerosis in rabbits. Indian Heart J 1992, 44:177-80.
68. Taguchi K, Hagiwara Y, Kajiyama K, Suzuki Y. Pharmacological studies of Houttuyniae herbal: the anti-inflammatory effect of quercetin. Yakuga Zasshi 1993, 113:327-33.
69. Tieppo J, Verselino R, Dias AS. Evaluation of the protective effects of quercetin in the hepatopulmonary syndrome. Food Chem Toxicol 2007, 45:1140-6.
70. Wilmink TB, Quick CR, Day NE. The association between cigarette smoking and abdominal aortic aneurysms. J Vasc Surg 1999, 30:1099-105.
71. Yang Xf, Wang SY, Zhao RC, Ao SQ, Xu LC, Wang XR. Changes in tissue metals after cadmium intoxication and intervention with chlorpromazine in male rats. Biomed Environ Sci 2003, 31:19-25.
72. Yavuz T, Delibas N, Yildirim B, Altuntas I, Candir O, Cora A, Karahan N, Ibrisim E, Kutsal A. Vascular wall damage in rats induced by methidathion and ameliorating effect of vitamins E and C. Arch Toxicol 2004, 78:655-9.
73. Zilversmit BB, Davis AK. Micro determination of plasma phospholipids by trichloroacetic acid precipitation. J Lab Clin Med 1950, 35:155-60.
74. Zlatkis A, Zak B, Boyle GJ. A simple method for determination of serum cholesterol. J Clin Med 1953, 41:486-92.