Frequency of microorganisms isolated in patients with bacteremia in intensive care units in Colombia and their resistance profiles

Brazilian Journal of Infectious Diseases

Volumn 17, Issue 3, 2013, Pages 346-352

  Cortes, Jorge Alberto ^a   Leal, Aura Lucía ^a,b   Montañez, Anita María ^a   Buitrago, Giancarlo ^a   Castillo, Juan Sebastián ^a   Guzman, Lucy ^c  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^c HOSPITAL UNIVERSITARIO DE LA SAMARITANA   (Colombia)

Author keywords

Anti bacterial agents; Bacteremia; Colombia epidemiology; Drug resistance; Epidemiologic surveillance; Intensive care unit

Indexed keywords

CARBAPENEM; CEFEPIME; CEFTAZIDIME; CEPHALOSPORIN; CIPROFLOXACIN; GENTAMICIN; IMIPENEM; MEROPENEM; OXACILLIN; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTEREMIA; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; COAGULASE NEGATIVE STAPHYLOCOCCUS; COLOMBIA; CRITICALLY ILL PATIENT; ENTEROBACTER CLOACAE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FOLLOW UP; HUMAN; INTENSIVE CARE UNIT; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; MULTIDRUG RESISTANCE; NONHUMAN; OBSERVATIONAL STUDY; PSEUDOMONAS AERUGINOSA; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACTEREMIA; COLOMBIA; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; INTENSIVE CARE UNITS; MICROBIAL SENSITIVITY TESTS; POPULATION SURVEILLANCE;

EID: 84878382221     PISSN: 14138670     EISSN: 16784391     Source Type: Journal    
DOI: 10.1016/j.bjid.2012.10.022     Document Type: Article

References (28)

1. Lizaso D., Aguilera C.K., Correa M., et al. Epidemiología y factores de riesgo de mortalidad de las bacteriemias intrahospitalarias por bacilos gramnegativos. Rev Chilena Infectol 2008, 25:368-373.
2. WHO. Prevention of hospital-acquired infections: a practical guide; 2002 (updated 2002; cited). Available from: [Revised: march 7, 2011]. http://www.who.int/csr/resources/publications/drugresist/WHO_CDS_CSR_EPH_2002_12/en/.
3. Ribas R.M., Freitas C., Gontijo Filho P.P. Nosocomial bloodstream infections: organisms, risk factors and resistant phenotypes in the Brazilian University Hospital. Braz J Infect Dis 2007, 11:351-354.
4. Leal A.L., Eslava-Schmalbach J., Alvarez C., Buitrago G., Mendez M. Canales endémicos y marcadores de resistencia bacteriana, en instituciones de tercer nivel de Bogotá, Colombia. Rev Salud Publica (Bogota) 2006, 8:59-70.
5. Institute CaLS M100-S18, performance standards for antimicrobial susceptibility testing. Eighteen informational supplement 2008, CLSI, Wayne, PA.
6. O'Brien T.F., Stelling J.M. WHONET: removing obstacles to the full use of information about antimicrobial resistance. Diagn Microbiol Infect Dis 1996, 25:162-168.
7. Sader H.S., Jones R.N., Andrade-Baiocchi S., Biedenbach D.J. Four-year evaluation of frequency of occurrence and antimicrobial susceptibility patterns of bacteria from bloodstream infections in Latin American medical centers. Diagn Microbiol Infect Dis 2002, 44:273-280.
8. Alvarez C., Cortes J., Arango A., Correa C., Leal A. Resistencia antimicrobiana en Unidades de Cuidado Intensivo de Bogotá, Colombia, 2001-2003. Rev Salud Publica (Bogota) 2006, 8:86-101.
9. Tuon F.F., Gortz L.W., Rocha J.L. Risk factors for pan-resistant Pseudomonas aeruginosa bacteremia and the adequacy of antibiotic therapy. Braz J Infect Dis 2012, 16:351-356.
10. Munoz P., Cruz A.F., Rodriguez-Creixems M., Bouza E. Gram-negative bloodstream infections. Int J Antimicrob Agents 2008, 32:S10-S14.
11. Tenorio M.T., Porfirio Z., Lopes A.C., Cendon S. Clinical and microbiological characteristics of bloodstream infections in a tertiary hospital in Maceio, Alagoas, Brazil. Braz J Infect Dis 2010, 14:175-179.
12. Hidron A.I., Edwards J.R., Patel J., et al. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007. Infect Control Hosp Epidemiol 2008, 29:996-1011.
13. Patwardhan R.B., Dhakephalkar P.K., Niphadkar K.B., Chopade B.A. A study on nosocomial pathogens in ICU with special reference to multiresistant Acinetobacter baumannii harbouring multiple plasmids. Indian J Med Res 2008, 128:178-187.
14. Olaechea P.M., Alvarez-Lerma F., Palomar M., et al. Impact of primary and intravascular catheter-related bacteremia due to coagulase-negative staphylococci in critically ill patients. Med Intensiva 2011, 35:217-225.
15. Secchi C., Antunes A.L., Perez L.R., Cantarelli V.V., d'Azevedo P.A. Identification and detection of methicillin resistance in non-epidermidis coagulase-negative staphylococci. Braz J Infect Dis 2008, 12:316-320.
16. von Eiff C., Peters G., Heilmann C. Pathogenesis of infections due to coagulase-negative staphylococci. Lancet Infect Dis 2002, 2:677-685.
17. Alvarez C.A., Yomayusa N., Leal A.L., et al. Nosocomial infections caused by community-associated methicillin-resistant Staphylococcus aureus in Colombia. Am J Infect Control 2010, 38:315-318.
18. Arias C.A., Rincon S., Chowdhury S., et al. MRSA USA300 clone and VREF-a U.S-Colombian connection?. N Engl J Med 2008, 359:2177-2179.
19. Marschall J., Agniel D., Fraser V.J., Doherty J., Warren D.K. Gram-negative bacteraemia in non-ICU patients: factors associated with inadequate antibiotic therapy and impact on outcomes. J Antimicrob Chemother 2008, 61:1376-1383.
20. Briceno D.F., Correa A., Valencia C., et al. Antimicrobial resistance of Gram negative bacilli isolated from tertiary-care hospitals in Colombia. Biomedica 2010, 30:371-381.
21. Hernandez J.R., Pascual A., Canton R., Martinez-Martinez L. Escherichia coli y Klebsiella pneumoniae productores de betalactamasas de espectro extendido en hospitales españoles (Proyecto GEIH-BLEE 2000). Enferm Infecc Microbiol Clin 2003, 21:77-82.
22. Saavedra S.Y., Nunez J.C., Pulido I.Y., et al. Characterisation of carbapenem-resistant Acinetobacter calcoaceticus-A. baumannii complex isolates in a third-level hospital in Bogota, Colombia. Int J Antimicrob Agents 2008, 31:389-391.
23. Nordmann P., Cuzon G., Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 2009, 9:228-236.
24. van Delden C. Pseudomonas aeruginosa bloodstream infections: how should we treat them?. Int J Antimicrob Agents 2007, 30:S71-S75.
25. Morales I.R. Terapia de bacterias productoras de b-lactamasas de espectro extendido. Rev Chil Infectol 2003, 20(Suppl. 1):S7-S24.
26. Tognim M.C., Andrade S.S., Silbert S., Gales A.C., Jones R.N., Sader H.S. Resistance trends of Acinetobacter spp. in Latin America and characterization of international dissemination of multi-drug resistant strains: five-year report of the SENTRY Antimicrobial Surveillance Program. Int J Infect Dis 2004, 8:284-291.
27. Zavascki A.P., Cruz R.P., Goldani L.Z. Risk factors for imipenem-resistant Pseudomonas aeruginosa: a comparative analysis of two case-control studies in hospitalized patients. J Hosp Infect 2005, 59:96-101.
28. Bax R., Bywater R., Cornaglia G., et al. Surveillance of antimicrobial resistance-what, how and whither?. Clin Microbiol Infect 2001, 7:316-325.