A cardiomyocyte-based biosensor for antiarrhythmic drug evaluation by simultaneously monitoring cell growth and beating

Biosensors and Bioelectronics

Volumn 49, Issue , 2013, Pages 9-13

  Wang, Tianxing ^a,b   Hu, Ning ^a   Cao, Jiayue ^a   Wu, Jieying ^a   Su, Kaiqi ^b   Wang, Ping ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ACEA Bio (Hangzhou) Co Ltd   (China)

Author keywords

Cardiotoxicity; Cell based biosensor; Pharmacological assays; Primary neonatal rat cardiomyocyte; Real time cell analysis

Indexed keywords

ADVANCED SENSORS; ANTIARRHYTHMIC DRUG; CARDIOMYOCYTES; CARDIOTOXICITY; CELL ANALYSIS; CELL-BASED BIOSENSOR; DETECTION TECHNOLOGY; PHARMACEUTICAL INDUSTRY;

BIOSENSORS;

ANTIARRHYTHMIC AGENT; FLECAINIDE; VERAPAMIL;

ANIMAL CELL; ARTICLE; BIOSENSOR; BIOTECHNOLOGY; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; HEART BEAT; HEART MUSCLE CELL; MEDICAL DEVICE; MONITORING; NEWBORN; NONHUMAN; PERFORMANCE; RAT;

CARDIOTOXICITY; CELL-BASED BIOSENSOR; PHARMACOLOGICAL ASSAYS; PRIMARY NEONATAL RAT CARDIOMYOCYTE; REAL TIME CELL ANALYSIS;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; BIOSENSING TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; EQUIPMENT DESIGN; FLECAINIDE; HUMANS; MYOCYTES, CARDIAC; RATS; VERAPAMIL;

RATTUS;

EID: 84878376886     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2013.04.039     Document Type: Article

References (27)

1. Braam S.R., Tertoolen L., Van De Stolpe A., Meyer T., Passier R., Mummery C.L. Stem Cell Research 2010, 4(2):107-116.
2. Ceriotti L., Ponti J., Broggi F., Kob A., Drechsler S., Thedinga E., Colpo P., Sabbioni E., Ehret R., Rossi F. Sensors and Actuators B: Chemical 2007, 123(2):769-778.
3. Corcoran C., Rechnitz G. Trends in Biotechnology 1985, 3(4):92-96.
4. Giaever I., Keese C. Proceedings of the National Academy of Sciences USA 1984, 81(12):3761.
5. Giorgi M.A., Bolanos R., Gonzalez C.D., Di Girolamo G. Current Drug Safety 2010, 5(1):54-57.
6. Heer F., Franks W., Blau A., Taschini S., Ziegler C., Hierlemann A., Baltes H. Biosensors and Bioelectronics 2004, 20(2):358-366.
7. Kammermann, M., Denelavas, A., Imbach, A., Grether, U., Dehmlow, H., Apfel, C., Hertel, C., 2011. Biochemical and Biophysical Research Communications.
8. Keese C.R., Bhawe K., Wegener J., Giaever I. Biotechniques 33(4) 2002, 842-844(846):848-850.
9. Kim S.B., Bae H., Cha J.M., Moon S.J., Dokmeci M.R., Cropek D.M., Khademhosseini A. Lab on a Chip 2011, 11(10):1801-1807.
10. Lawrence C., Pollard C., Hammond T., Valentin J.P. British Journal of Pharmacology 2008, 154(7):1516-1522.
11. Liu Q., Yu H., Tan Z., Cai H., Ye W., Zhang M., Wang P. Sensors and Actuators B-Chemical 2011, 155(1):214-219.
12. Luong J.H.T., Habibi-Rezaei M., Meghrous J., Xiao C., Keith B., Kamen A. Analytical Chemistry 2001, 73(8):1844-1848.
13. Moss A.J., Kass R.S. Journal of Clinical Investigation 2005, 115(8):2018.
14. Natarajan, A., Stancescu, M., Dhir, V., Armstrong, C., Sommerhage, F., Hickman, J.J., Molnar, P., 2011. Biomaterials.
15. Opp D., Wafula B., Lim J., Huang E., Lo J.C., Lo C.M. Biosensors and Bioelectronics 2009, 24(8):2625-2629.
16. Pancrazio J., Whelan J., Borkholder D., Ma W., Stenger D. American Journal of Preventive Medicine 1999, 27(6):697-711.
17. Ramos E., O'Leary M.E. Journal of Physiology 2004, 560(1):37-49.
18. Said R., Aykut Ü. Journal of Visualized Experiments 2011, 50.
19. Smout M.J., Laha T., Mulvenna J., Sripa B., Suttiprapa S., Jones A., Brindley P.J., Loukas A. PLoS Pathogens 2009, 5(10):e1000611.
20. Srinivasan V., Sivaramakrishnan H., Karthikeyan B. Scientia Pharmaceutica 79 2011, 3:555.
21. Stenger D.A., Gross G.W., Keefer E.W., Shaffer K.M., Andreadis J.D., Ma W., Pancrazio J.J. Trends in Biotechnology 2001, 19(8):304-309.
22. Thakur, M., Mergel, K., Weng, A., Frech, S., Gilabert-Oriol, R., Bachran, D., Melzig, M.F., Fuchs, H., 2012. Biosensors and Bioelectronics.
23. Wang Z., Fermini B., Nattel S. Journal of Pharmacology and Experimental Therapeutics 1993, 267(2):575-581.
24. Wegener J., Abrams D., Willenbrink W., Galla H.-J., Janshoff A. Biotechniques 2004, 37(4):590-597.
25. Xiao C., Lachance B., Sunahara G., Luong J.H.T. Analytical Chemistry 2002, 74(22):5748-5753.
26. Xiao L., Hu Z., Zhang W., Wu C., Yu H., Wang P. Biosensors and Bioelectronics 2010, 26(4):1493-1499.
27. Ziegler C. Fresenius Journal of Analytical Chemistry 2000, 366(6):552-559.