Evaluation of doxorubicin toxicity on cardiomyocytes using a dual functional extracellular biochip

Biosensors and Bioelectronics

Volumn 26, Issue 4, 2010, Pages 1493-1499

  Xiao, Lidan ^a,b   Hu, Zhaoyin ^a   Zhang, Wei ^a   Wu, Chengxiong ^a   Yu, Hui ^a,b   Wang, Ping ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Cardiomyocytes; Cell based biosensor; Doxorubincin toxicity; Electrophysiology; Pharmacological assays

Indexed keywords

ADRIAMYCIN; CANCER TREATMENT; CARDIOMYOCYTES; CARDIOTOXICITY; CELL SUBSTRATES; CELL-BASED BIOSENSOR; CHEMOTHERAPY AGENTS; CLINICAL DRUGS; CLINICAL TREATMENTS; CLINICAL USE; DOXORUBICIN; DOXORUBINCIN TOXICITY; DRUG EVALUATION; EXTRACELLULAR; FIELD POTENTIAL; HIGH CONCENTRATION; HIGH-THROUGHPUT; INTER-DIGITATED ELECTRODES; MICROELECTRODE ARRAY; PHARMACOLOGICAL ASSAYS; PHYSICAL STATE;

BIOSENSORS; CELL DEATH; CHEMOTHERAPY; ELECTROPHYSIOLOGY; MICROELECTRODES; NEUROLOGY; POPULATION STATISTICS; TOXICITY;

CELL CULTURE;

DOXORUBICIN;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BIOCHIP; BIOSENSOR; CALCIUM TRANSPORT; CARDIOTOXICITY; CELL DEATH; CELL FUNCTION; CONCENTRATION RESPONSE; CONTINUOUS PROCESS; CONTROLLED STUDY; DRUG SCREENING; EQUIPMENT DESIGN; EXTRACELLULAR SPACE; MICROELECTRODE; NEWBORN; NONHUMAN; RAT; REACTION TIME; TOXICITY TESTING;

ACTION POTENTIALS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOSENSING TECHNIQUES; CELL DEATH; CELLS, CULTURED; DOXORUBICIN; DRUG EVALUATION, PRECLINICAL; ELECTRIC IMPEDANCE; ELECTROPHYSIOLOGICAL PHENOMENA; EQUIPMENT DESIGN; EXTRACELLULAR SPACE; HUMANS; MYOCYTES, CARDIAC; RATS;

EID: 78649731910     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2010.07.093     Document Type: Article

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