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Volumn 11, Issue 1, 2013, Pages

Future perspectives in melanoma research. Meeting report from the " Melanoma Bridge. Napoli, December 2nd-4th 2012"

(38)  Ascierto, Paolo A a   Grimaldi, Antonio M a   Acquavella, Nicolas b   Borgognoni, Lorenzo c   Calabrò, Luana d   Cascinelli, Natale e   Cesano, Alessandra f   Del Vecchio, Michele g   Eggermont, Alexander M h   Faries, Mark i   Ferrone, Soldano j   Fox, Bernard A k,l   Gajewski, Thomas F m   Galon, Jérôme n,o   Gnjatic, Sacha p   Gogas, Helen q   Kashani Sabet, Mohammed r   Kaufman, Howard L s   Larkin, James t   Lo, Roger S u   more..


Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BIOLOGICAL MARKER; CANCER VACCINE; CELECOXIB; CISPLATIN; COBIMETINIB; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; DABRAFENIB; DACARBAZINE; FOTEMUSTINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; INTERFERON; INTERLEUKIN 2; IPILIMUMAB; MELANOMA ANTIGEN 3; MELANOMA ANTIGEN 3 VACCINE; MELPHALAN; ONAMELATUCEL L; PACLITAXEL; PALBOCICLIB; PEGINTERFERON ALPHA2B; PLACEBO; TALIMOGENE LAHERPAREPVEC; TEMOZOLOMIDE; TICILIMUMAB; TRAMETINIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACCINIA VACCINE; VEMURAFENIB; VINBLASTINE;

EID: 84878374050     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-137     Document Type: Conference Paper
Times cited : (18)

References (116)
  • 1
    • 0014481136 scopus 로고
    • The histogenesis and biologic behavior of primary human malignant melanomas of the skin
    • Clark WH, From L, Bernardino EA, Mihm MC. The histogenesis and biologic behavior of primary human malignant melanomas of the skin. Cancer Res 1969, 29:705-727.
    • (1969) Cancer Res , vol.29 , pp. 705-727
    • Clark, W.H.1    From, L.2    Bernardino, E.A.3    Mihm, M.C.4
  • 5
    • 0030696676 scopus 로고    scopus 로고
    • T cell defined tumor antigens
    • 10.1016/S0952-7915(97)80050-7, 9368778
    • Van den Eynde BJ, van der Bruggen P. T cell defined tumor antigens. Curr Opin Immunol 1997, 9:684-693. 10.1016/S0952-7915(97)80050-7, 9368778.
    • (1997) Curr Opin Immunol , vol.9 , pp. 684-693
    • Van den Eynde, B.J.1    van der Bruggen, P.2
  • 6
    • 84892624845 scopus 로고    scopus 로고
    • Comprehensive preclinical model evaluating a protein-based MAGE-A3 specific cancer immunotherapy to fight against MAGE-A3 expressing tumors [abstract]
    • Gérard C, Baudson N, Ory T, Piccininno R, Brichard V. Comprehensive preclinical model evaluating a protein-based MAGE-A3 specific cancer immunotherapy to fight against MAGE-A3 expressing tumors [abstract]. Eur J Canc 2006, 4:39.
    • (2006) Eur J Canc , vol.4 , pp. 39
    • Gérard, C.1    Baudson, N.2    Ory, T.3    Piccininno, R.4    Brichard, V.5
  • 8
    • 79954580944 scopus 로고    scopus 로고
    • Identification of a gene expression signature predictive of clinical activity following MAGE-A3 ASCI treatment [abstract]
    • 2775557, 19139107
    • Louahed J, Lehmann F, Ulloa-Montoya F, Gruselle O, Dizier B, Vansteenkiste J, Kruit W, Brichard V. Identification of a gene expression signature predictive of clinical activity following MAGE-A3 ASCI treatment [abstract]. Mol Cancer Ther 2009, 8(12 supplements):1. 2775557, 19139107.
    • (2009) Mol Cancer Ther , vol.8 , Issue.12 SUPPL. , pp. 1
    • Louahed, J.1    Lehmann, F.2    Ulloa-Montoya, F.3    Gruselle, O.4    Dizier, B.5    Vansteenkiste, J.6    Kruit, W.7    Brichard, V.8
  • 10
    • 84862251087 scopus 로고    scopus 로고
    • The cancer vaccine collaborative: a new model of coordinated discovery
    • 3380350, 22896755
    • O'Donnell-Tormey J, McDermott EA. The cancer vaccine collaborative: a new model of coordinated discovery. Cancer Immun 2012, 12:10. 3380350, 22896755.
    • (2012) Cancer Immun , vol.12 , pp. 10
    • O'Donnell-Tormey, J.1    McDermott, E.A.2
  • 11
    • 35649015750 scopus 로고    scopus 로고
    • Interferon-α as adjuvant therapy for melanoma: An individual patient data meta-analysis of randomised trials [abstract]
    • abstr 8526, on behalf of International Malignant Melanoma Collaborative Group
    • Wheatley K, Ives N, Eggermont A, Kirkwood J, Cascinelli N, Markovic SN, Hancock B, Lee S, Suciu S, on behalf of International Malignant Melanoma Collaborative Group Interferon-α as adjuvant therapy for melanoma: An individual patient data meta-analysis of randomised trials [abstract]. Proc Am Soc Clin Oncol 2007, 25:478S. abstr 8526, on behalf of International Malignant Melanoma Collaborative Group.
    • (2007) Proc Am Soc Clin Oncol , vol.25
    • Wheatley, K.1    Ives, N.2    Eggermont, A.3    Kirkwood, J.4    Cascinelli, N.5    Markovic, S.N.6    Hancock, B.7    Lee, S.8    Suciu, S.9
  • 12
    • 77950576363 scopus 로고    scopus 로고
    • Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis
    • 10.1093/jnci/djq009, 20179267
    • Mocellin S, Pasquali S, Rossi CR, Nitti D. Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis. J Natl Cancer Inst 2010, 102:493-501. 10.1093/jnci/djq009, 20179267.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 493-501
    • Mocellin, S.1    Pasquali, S.2    Rossi, C.R.3    Nitti, D.4
  • 13
    • 33745989541 scopus 로고    scopus 로고
    • Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses
    • 10.1200/JCO.2005.05.2498, 16809739
    • Moschos SJ, Edington HD, Land SR, Rao UN, Jukic D, Shipe-Spotloe J, Kirkwood JM. Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses. J Clin Oncol 2006, 24:3164-3171. 10.1200/JCO.2005.05.2498, 16809739.
    • (2006) J Clin Oncol , vol.24 , pp. 3164-3171
    • Moschos, S.J.1    Edington, H.D.2    Land, S.R.3    Rao, U.N.4    Jukic, D.5    Shipe-Spotloe, J.6    Kirkwood, J.M.7
  • 14
    • 33947423447 scopus 로고    scopus 로고
    • Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b
    • 10.1158/1078-0432.CCR-06-1387, 17332298
    • Wang W, Edington HD, Rao UN, Jukic DM, Land SR, Ferrone S, Kirkwood JM. Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b. Clin Cancer Res 2007, 13:1523-1531. 10.1158/1078-0432.CCR-06-1387, 17332298.
    • (2007) Clin Cancer Res , vol.13 , pp. 1523-1531
    • Wang, W.1    Edington, H.D.2    Rao, U.N.3    Jukic, D.M.4    Land, S.R.5    Ferrone, S.6    Kirkwood, J.M.7
  • 17
    • 84864487810 scopus 로고    scopus 로고
    • A multi-factorial genetic model for prognostic assessment of high risk melanoma patients receiving adjuvant interferon
    • 10.1371/journal.pone.0040805, 3404079, 22911710
    • Wang E, Zhao Y, Monaco A, Uccellini L, Kirkwood JM, Spyropoulou-Vlachou M, Panelli MC, Marincola FM, Gogas H. A multi-factorial genetic model for prognostic assessment of high risk melanoma patients receiving adjuvant interferon. PLoS One 2012, 7:e40805. 10.1371/journal.pone.0040805, 3404079, 22911710.
    • (2012) PLoS One , vol.7
    • Wang, E.1    Zhao, Y.2    Monaco, A.3    Uccellini, L.4    Kirkwood, J.M.5    Spyropoulou-Vlachou, M.6    Panelli, M.C.7    Marincola, F.M.8    Gogas, H.9
  • 18
  • 20
    • 84863672266 scopus 로고    scopus 로고
    • Biomarkers on melanoma patient T cells associated with ipilimumab treatment
    • 10.1186/1479-5876-10-146, 3527361, 22788688
    • Wang W, Yu D, Sarnaik AA, Yu B, Hall M, Morelli D, Zhang Y, Zhao X, Weber JS. Biomarkers on melanoma patient T cells associated with ipilimumab treatment. J Transl Med 2012, 10:146. 10.1186/1479-5876-10-146, 3527361, 22788688.
    • (2012) J Transl Med , vol.10 , pp. 146
    • Wang, W.1    Yu, D.2    Sarnaik, A.A.3    Yu, B.4    Hall, M.5    Morelli, D.6    Zhang, Y.7    Zhao, X.8    Weber, J.S.9
  • 21
    • 3242683662 scopus 로고    scopus 로고
    • Single cell profiling of potentiated phospho-protein networks in cancer cells
    • 10.1016/j.cell.2004.06.028, 15260991
    • Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud T, Gjertsen BT, Nolan GP. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 2004, 118:217-228. 10.1016/j.cell.2004.06.028, 15260991.
    • (2004) Cell , vol.118 , pp. 217-228
    • Irish, J.M.1    Hovland, R.2    Krutzik, P.O.3    Perez, O.D.4    Bruserud, T.5    Gjertsen, B.T.6    Nolan, G.P.7
  • 22
    • 84863393783 scopus 로고    scopus 로고
    • Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts
    • 3632455, 22334473
    • Cesano A, Rosen DB, O'Meara P, Putta S, Gayko U, Spellmeyer DC, Cripe LD, Sun Z, Uno H, Litzow MR, Tallman MS, Paietta E. Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts. Cytometry B Clin Cytom 2012, 82:158-172. 3632455, 22334473.
    • (2012) Cytometry B Clin Cytom , vol.82 , pp. 158-172
    • Cesano, A.1    Rosen, D.B.2    O'Meara, P.3    Putta, S.4    Gayko, U.5    Spellmeyer, D.C.6    Cripe, L.D.7    Sun, Z.8    Uno, H.9    Litzow, M.R.10    Tallman, M.S.11    Paietta, E.12
  • 23
    • 78649515407 scopus 로고    scopus 로고
    • Modulated multiparametric phosphoflow cytometry in hematological malignancies: technology and clinical applications
    • 10.1016/j.beha.2010.07.002, 21112033
    • Covey TM, Cesano A. Modulated multiparametric phosphoflow cytometry in hematological malignancies: technology and clinical applications. Best Pract Res Clin Haematol 2010, 23:319-331. 10.1016/j.beha.2010.07.002, 21112033.
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 319-331
    • Covey, T.M.1    Cesano, A.2
  • 24
    • 77957978115 scopus 로고    scopus 로고
    • Single-cell network profiling (SCNP) by flow cytometry in autoimmune disease
    • 10.3109/08916931003674774, 20482423
    • Covey TM, Cesano A, Parkinson DR. Single-cell network profiling (SCNP) by flow cytometry in autoimmune disease. Autoimmunity 2010, 43:550-559. 10.3109/08916931003674774, 20482423.
    • (2010) Autoimmunity , vol.43 , pp. 550-559
    • Covey, T.M.1    Cesano, A.2    Parkinson, D.R.3
  • 25
    • 84856917555 scopus 로고    scopus 로고
    • Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age- and race-associated differences in immune signaling pathway activation
    • 10.4049/jimmunol.1102514, 3517183, 22246624
    • Longo DM, Louie B, Putta S, Evensen E, Ptacek J, Cordeiro J, Wang E, Pos Z, Hawtin RE, Marincola FM, Cesano A. Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age- and race-associated differences in immune signaling pathway activation. J Immunol 2012, 188:1717-1725. 10.4049/jimmunol.1102514, 3517183, 22246624.
    • (2012) J Immunol , vol.188 , pp. 1717-1725
    • Longo, D.M.1    Louie, B.2    Putta, S.3    Evensen, E.4    Ptacek, J.5    Cordeiro, J.6    Wang, E.7    Pos, Z.8    Hawtin, R.E.9    Marincola, F.M.10    Cesano, A.11
  • 29
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801
    • Kirkwood JM, Ibrahim JG, Sosman JA, Sondak VK, Agarwala SS, Ernstoff MS, Rao U. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J Clin Oncol 2001, 19:2370-2380.
    • (2001) J Clin Oncol , vol.19 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3    Sondak, V.K.4    Agarwala, S.S.5    Ernstoff, M.S.6    Rao, U.7
  • 32
    • 58149138892 scopus 로고    scopus 로고
    • Adjuvant therapy of melanoma with interferon: lessons of the past decade
    • 10.1186/1479-5876-6-62, 2605741, 18954464
    • Ascierto PA, Kirkwood JM. Adjuvant therapy of melanoma with interferon: lessons of the past decade. J Transl Med 2008, 6:62. 10.1186/1479-5876-6-62, 2605741, 18954464.
    • (2008) J Transl Med , vol.6 , pp. 62
    • Ascierto, P.A.1    Kirkwood, J.M.2
  • 33
    • 42549166042 scopus 로고    scopus 로고
    • Raf inhibitor stabilizes receptor for the type I interferon but inhibits its anti-proliferative effects in human malignantmelanoma cells
    • 10.4161/cbt.6.9.4569, 2254442, 17873516
    • Kumar KG, Liu J, Li Y, Yu D, Thomas-Tikhonenko A, Herlyn M, Fuchs SY. Raf inhibitor stabilizes receptor for the type I interferon but inhibits its anti-proliferative effects in human malignantmelanoma cells. Cancer Biol Ther 2007, 6:1437-1441. 10.4161/cbt.6.9.4569, 2254442, 17873516.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1437-1441
    • Kumar, K.G.1    Liu, J.2    Li, Y.3    Yu, D.4    Thomas-Tikhonenko, A.5    Herlyn, M.6    Fuchs, S.Y.7
  • 34
    • 84856069688 scopus 로고    scopus 로고
    • Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma
    • 10.1200/JCO.2011.37.5394, 3422533, 22184371
    • Tarhini AA, Cherian J, Moschos SJ, Tawbi HA, Shuai Y, Gooding WE, Sander C, Kirkwood JM. Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma. J Clin Oncol 2012, 30:322-328. 10.1200/JCO.2011.37.5394, 3422533, 22184371.
    • (2012) J Clin Oncol , vol.30 , pp. 322-328
    • Tarhini, A.A.1    Cherian, J.2    Moschos, S.J.3    Tawbi, H.A.4    Shuai, Y.5    Gooding, W.E.6    Sander, C.7    Kirkwood, J.M.8
  • 35
    • 84867544962 scopus 로고    scopus 로고
    • PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines
    • 10.1158/0008-5472.CAN-12-1187, 22915761
    • Peng W, Liu C, Xu C, Lou Y, Chen J, Yang Y, Yagita H, Overwijk WW, Lizée G, Radvanyi L, Hwu P. PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines. Cancer Res 2012, 72:5209-5218. 10.1158/0008-5472.CAN-12-1187, 22915761.
    • (2012) Cancer Res , vol.72 , pp. 5209-5218
    • Peng, W.1    Liu, C.2    Xu, C.3    Lou, Y.4    Chen, J.5    Yang, Y.6    Yagita, H.7    Overwijk, W.W.8    Lizée, G.9    Radvanyi, L.10    Hwu, P.11
  • 36
    • 78449242173 scopus 로고    scopus 로고
    • E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completed resected stage III-IV melanoma
    • abstract
    • Lawson DH, Lee SJ, Tahrini AA, Margolin KK, Ernstoff MS, Kirkwood JM. E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completed resected stage III-IV melanoma. J Clin Oncol 2010, 28(suppl):8507. abstract.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL , pp. 8507
    • Lawson, D.H.1    Lee, S.J.2    Tahrini, A.A.3    Margolin, K.K.4    Ernstoff, M.S.5    Kirkwood, J.M.6
  • 37
    • 84870894374 scopus 로고    scopus 로고
    • Phase III trial of high-dose interferon alpha-2b versus cisplatin, vinblastine, DTIC plus IL-2 and interferon in patients with high-risk melanoma (SWOG S0008): an intergroup study of CALGB, COG, ECOG, and SWOG [abstract]
    • abstr
    • Flaherty LE, Moon J, Atkins MB, Tuthill R, Thompson JA, Vetto JT, Haluska FG, Pappo AS, Sosman JA, Redman BG, Ribas A, Kirkwood JM, Sondak VK. Phase III trial of high-dose interferon alpha-2b versus cisplatin, vinblastine, DTIC plus IL-2 and interferon in patients with high-risk melanoma (SWOG S0008): an intergroup study of CALGB, COG, ECOG, and SWOG [abstract]. J Clin Oncol 2012, 30:8504. abstr.
    • (2012) J Clin Oncol , vol.30 , pp. 8504
    • Flaherty, L.E.1    Moon, J.2    Atkins, M.B.3    Tuthill, R.4    Thompson, J.A.5    Vetto, J.T.6    Haluska, F.G.7    Pappo, A.S.8    Sosman, J.A.9    Redman, B.G.10    Ribas, A.11    Kirkwood, J.M.12    Sondak, V.K.13
  • 38
    • 0031852722 scopus 로고    scopus 로고
    • Gp100/pmel 17 is a murine tumor rejection antigen: induction of " self" -reactive, tumoricidal T cells using high-affinity, altered peptide ligand
    • 10.1084/jem.188.2.277, 2212458, 9670040
    • Overwijk WW, Tsung A, Irvine KR, Parkhurst MR, Goletz TJ, Tsung K, Carroll MW, Liu C, Moss B, Rosenberg SA, Restifo NP. gp100/pmel 17 is a murine tumor rejection antigen: induction of " self" -reactive, tumoricidal T cells using high-affinity, altered peptide ligand. J Exp Med 1998, 188:277-286. 10.1084/jem.188.2.277, 2212458, 9670040.
    • (1998) J Exp Med , vol.188 , pp. 277-286
    • Overwijk, W.W.1    Tsung, A.2    Irvine, K.R.3    Parkhurst, M.R.4    Goletz, T.J.5    Tsung, K.6    Carroll, M.W.7    Liu, C.8    Moss, B.9    Rosenberg, S.A.10    Restifo, N.P.11
  • 40
    • 77957982878 scopus 로고    scopus 로고
    • Analysis of the genome to personalize therapy for melanoma
    • 10.1038/onc.2010.323, 3169242, 20697348
    • Davies MA, Samuels Y. Analysis of the genome to personalize therapy for melanoma. Oncogene 2010, 29:5545-5555. 10.1038/onc.2010.323, 3169242, 20697348.
    • (2010) Oncogene , vol.29 , pp. 5545-5555
    • Davies, M.A.1    Samuels, Y.2
  • 45
    • 44349102029 scopus 로고    scopus 로고
    • Mutant B-RAF mediates resistance to anoikis via Bad and Bim
    • 10.1038/sj.onc.1211003, 18246127
    • Boisvert-Adamo K, Aplin AE. Mutant B-RAF mediates resistance to anoikis via Bad and Bim. Oncogene 2008, 27:3301-3312. 10.1038/sj.onc.1211003, 18246127.
    • (2008) Oncogene , vol.27 , pp. 3301-3312
    • Boisvert-Adamo, K.1    Aplin, A.E.2
  • 46
    • 33745859743 scopus 로고    scopus 로고
    • The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells
    • 10.1084/jem.20051848, 2118331, 16801397
    • Sumimoto H, Imabayashi F, Iwata T, Kawakami Y. The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells. J Exp Med 2006, 203:1651-1656. 10.1084/jem.20051848, 2118331, 16801397.
    • (2006) J Exp Med , vol.203 , pp. 1651-1656
    • Sumimoto, H.1    Imabayashi, F.2    Iwata, T.3    Kawakami, Y.4
  • 50
    • 84879177690 scopus 로고    scopus 로고
    • Clinical Responses to Vemurafenib in Patients with Metastatic Papillary Thyroid Cancer Harboring V600EBRAF Mutation
    • [Epub ahead of print] PubMed PMID: 23489023
    • Kim K, Cabanillas M, Lazar AJ, Williams MD, Sanders DL, Ilagan JL, Nolop K, Lee RJ, Sherman SI. Clinical Responses to Vemurafenib in Patients with Metastatic Papillary Thyroid Cancer Harboring V600EBRAF Mutation. Thyroid 2013, [Epub ahead of print] PubMed PMID: 23489023.
    • (2013) Thyroid
    • Kim, K.1    Cabanillas, M.2    Lazar, A.J.3    Williams, M.D.4    Sanders, D.L.5    Ilagan, J.L.6    Nolop, K.7    Lee, R.J.8    Sherman, S.I.9
  • 51
    • 84892625269 scopus 로고    scopus 로고
    • A Study of Vemurafenib in Patients With BRAF V600 Mutation-Positive Cancers (NCT01524978)
    • A Study of Vemurafenib in Patients With BRAF V600 Mutation-Positive Cancers (NCT01524978). http://www.clinicaltrials.gov.
  • 55
    • 84878926682 scopus 로고    scopus 로고
    • Phase Ib study of vemurafenib in combination with the MEK inhibitor, GDC-0973, in patients (pts) with unresectable or metastatic BRAFV600 mutated melanoma (BRIM7) [abstract]
    • ixe20
    • Gonzalez R, Ribas A, Daud A, Pavlick A, Gajewski TF, Puzanov I, Teng MSL, Chan I, Choong NW, McArthur G. Phase Ib study of vemurafenib in combination with the MEK inhibitor, GDC-0973, in patients (pts) with unresectable or metastatic BRAFV600 mutated melanoma (BRIM7) [abstract]. Ann Oncol 2012, 23:ixe20.
    • (2012) Ann Oncol , vol.23
    • Gonzalez, R.1    Ribas, A.2    Daud, A.3    Pavlick, A.4    Gajewski, T.F.5    Puzanov, I.6    Teng, M.S.L.7    Chan, I.8    Choong, N.W.9    McArthur, G.10
  • 61
    • 0036885116 scopus 로고    scopus 로고
    • Oncolytic viruses
    • 10.1038/nrc948, 12459732
    • Chiocca EA. Oncolytic viruses. Nat Rev Cancer 2002, 2:938-950. 10.1038/nrc948, 12459732.
    • (2002) Nat Rev Cancer , vol.2 , pp. 938-950
    • Chiocca, E.A.1
  • 62
    • 16844362403 scopus 로고    scopus 로고
    • Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses
    • 10.1158/1078-0432.CCR-04-1380, 15788693
    • Kudo-Saito C, Schlom J, Hodge JW. Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses. Clin Cancer Res 2005, 11:2416-2426. 10.1158/1078-0432.CCR-04-1380, 15788693.
    • (2005) Clin Cancer Res , vol.11 , pp. 2416-2426
    • Kudo-Saito, C.1    Schlom, J.2    Hodge, J.W.3
  • 64
    • 85084273560 scopus 로고    scopus 로고
    • Gut commensal bacteria determine cancer response to treatment by modulating systemic inflammation [abstract]
    • Trinchieri G. Gut commensal bacteria determine cancer response to treatment by modulating systemic inflammation [abstract]. Ann Oncol 2013, 24:i12.
    • (2013) Ann Oncol , vol.24
    • Trinchieri, G.1
  • 65
    • 84859401430 scopus 로고    scopus 로고
    • Cancer and Inflammation: An old intuition with rapidly evolving new concepts
    • Trinchieri G. Cancer and Inflammation: An old intuition with rapidly evolving new concepts. Annual Rev Immunology 2012, 30:677-706.
    • (2012) Annual Rev Immunology , vol.30 , pp. 677-706
    • Trinchieri, G.1
  • 67
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • 10.1038/nature07205, 18650914
    • Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008, 454:436-444. 10.1038/nature07205, 18650914.
    • (2008) Nature , vol.454 , pp. 436-444
    • Mantovani, A.1    Allavena, P.2    Sica, A.3    Balkwill, F.4
  • 68
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • 10.1172/JCI59643, 3287223, 22378047
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2012, 122:787-795. 10.1172/JCI59643, 3287223, 22378047.
    • (2012) J Clin Invest , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 69
    • 39649098678 scopus 로고    scopus 로고
    • Tumour immunity: effector response to tumour and role of the microenvironment
    • 10.1016/S0140-6736(08)60241-X, 18275997
    • Mantovani A, Romero P, Palucka AK, Marincola FM. Tumour immunity: effector response to tumour and role of the microenvironment. Lancet 2008, 371:771-783. 10.1016/S0140-6736(08)60241-X, 18275997.
    • (2008) Lancet , vol.371 , pp. 771-783
    • Mantovani, A.1    Romero, P.2    Palucka, A.K.3    Marincola, F.M.4
  • 70
    • 84882637084 scopus 로고    scopus 로고
    • Tumor-associated macrophages: functional diversity, clinical significance and open questions
    • in press
    • Biswas SK, Allavena P, Mantovani A. Tumor-associated macrophages: functional diversity, clinical significance and open questions. Semin Immunopathology 2013, in press.
    • (2013) Semin Immunopathology
    • Biswas, S.K.1    Allavena, P.2    Mantovani, A.3
  • 71
    • 77952316540 scopus 로고    scopus 로고
    • An integrated view of humoral innate immunity: pentraxins as a paradigm
    • 10.1146/annurev-immunol-030409-101305, 19968561
    • Bottazzi B, Doni A, Garlanda C, Mantovani A. An integrated view of humoral innate immunity: pentraxins as a paradigm. Annu Rev Immunol 2010, 28:157-183. 10.1146/annurev-immunol-030409-101305, 19968561.
    • (2010) Annu Rev Immunol , vol.28 , pp. 157-183
    • Bottazzi, B.1    Doni, A.2    Garlanda, C.3    Mantovani, A.4
  • 75
    • 0142058245 scopus 로고    scopus 로고
    • Interobserver reproducibility of ulceration assessment in primary cutaneous melanomas
    • 10.1016/S0959-8049(03)00325-3, 12932663
    • Spatz A, Cook MG, Elder DE, Piepkorn M, Ruiter DJ, Barnhill RL. Interobserver reproducibility of ulceration assessment in primary cutaneous melanomas. Eur J Cancer 2003, 39:1861-1865. 10.1016/S0959-8049(03)00325-3, 12932663.
    • (2003) Eur J Cancer , vol.39 , pp. 1861-1865
    • Spatz, A.1    Cook, M.G.2    Elder, D.E.3    Piepkorn, M.4    Ruiter, D.J.5    Barnhill, R.L.6
  • 77
  • 78
    • 25844465690 scopus 로고    scopus 로고
    • Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial
    • 10.1016/S0140-6736(05)67482-X, 16198768, EORTC Melanoma Group
    • Eggermont AM, Suciu S, MacKie R, Ruka W, Testori A, Kruit W, Punt CJ, Delauney M, Sales F, Groenewegen G, Ruiter DJ, Jagiello I, Stoitchkov K, Keilholz U, Lienard D, EORTC Melanoma Group Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial. Lancet 2005, 366:1189-1196. 10.1016/S0140-6736(05)67482-X, 16198768, EORTC Melanoma Group.
    • (2005) Lancet , vol.366 , pp. 1189-1196
    • Eggermont, A.M.1    Suciu, S.2    MacKie, R.3    Ruka, W.4    Testori, A.5    Kruit, W.6    Punt, C.J.7    Delauney, M.8    Sales, F.9    Groenewegen, G.10    Ruiter, D.J.11    Jagiello, I.12    Stoitchkov, K.13    Keilholz, U.14    Lienard, D.15
  • 79
    • 46749103710 scopus 로고    scopus 로고
    • Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
    • 10.1016/S0140-6736(08)61033-8, 18620949, EORTC Melanoma Group
    • Eggermont AM, Suciu S, Santinami M, Testori A, Kruit WH, Marsden J, Punt CJ, Salès F, Gore M, Mackie R, Kusic Z, Dummer R, Hauschild A, Musat E, Spatz A, Keilholz U, EORTC Melanoma Group Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet 2008, 372:117-126. 10.1016/S0140-6736(08)61033-8, 18620949, EORTC Melanoma Group.
    • (2008) Lancet , vol.372 , pp. 117-126
    • Eggermont, A.M.1    Suciu, S.2    Santinami, M.3    Testori, A.4    Kruit, W.H.5    Marsden, J.6    Punt, C.J.7    Salès, F.8    Gore, M.9    Mackie, R.10    Kusic, Z.11    Dummer, R.12    Hauschild, A.13    Musat, E.14    Spatz, A.15    Keilholz, U.16
  • 84
    • 84869499716 scopus 로고    scopus 로고
    • Successful rechallenge in two patients with BRAF-V600-mutant melanoma who experienced previous progression during treatment with a selective BRAF inhibitor
    • 10.1097/CMR.0b013e3283541541, 22584957
    • Seghers AC, Wilgenhof S, Lebbé C, Neyns B. Successful rechallenge in two patients with BRAF-V600-mutant melanoma who experienced previous progression during treatment with a selective BRAF inhibitor. Melanoma Res 2012, 22:466-472. 10.1097/CMR.0b013e3283541541, 22584957.
    • (2012) Melanoma Res , vol.22 , pp. 466-472
    • Seghers, A.C.1    Wilgenhof, S.2    Lebbé, C.3    Neyns, B.4
  • 85
    • 84857631433 scopus 로고    scopus 로고
    • Management of brain metastasis: past lessons, modern management, and future considerations
    • 10.1007/s11912-011-0205-9, 22071681
    • Koay E, Sulman EP. Management of brain metastasis: past lessons, modern management, and future considerations. Curr Oncol Rep 2012, 14:70-78. 10.1007/s11912-011-0205-9, 22071681.
    • (2012) Curr Oncol Rep , vol.14 , pp. 70-78
    • Koay, E.1    Sulman, E.P.2
  • 86
    • 84855179546 scopus 로고    scopus 로고
    • Vemurafenib for melanoma metastases to the brain
    • 10.1056/NEJMc1111672, 22188003
    • Rochet NM, Kottschade LA, Markovic SN. Vemurafenib for melanoma metastases to the brain. N Engl J Med 2011, 365:2439-2441. 10.1056/NEJMc1111672, 22188003.
    • (2011) N Engl J Med , vol.365 , pp. 2439-2441
    • Rochet, N.M.1    Kottschade, L.A.2    Markovic, S.N.3
  • 87
    • 23744475685 scopus 로고    scopus 로고
    • The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms
    • 10.1016/j.it.2005.07.004, 16039904
    • Engelhardt B, Ransohoff RM. The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol 2005, 26:485-495. 10.1016/j.it.2005.07.004, 16039904.
    • (2005) Trends Immunol , vol.26 , pp. 485-495
    • Engelhardt, B.1    Ransohoff, R.M.2
  • 89
    • 33644753906 scopus 로고    scopus 로고
    • Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel
    • 10.1158/1078-0432.CCR-05-1634, 16489089
    • Desai N, Trieu V, Yao Z, Louie L, Ci S, Yang A, Tao C, De T, Beals B, Dykes D, Noker P, Yao R, Labao E, Hawkins M, Soon-Shiong P. Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel. Clin Cancer Res 2006, 12:1317-1324. 10.1158/1078-0432.CCR-05-1634, 16489089.
    • (2006) Clin Cancer Res , vol.12 , pp. 1317-1324
    • Desai, N.1    Trieu, V.2    Yao, Z.3    Louie, L.4    Ci, S.5    Yang, A.6    Tao, C.7    De, T.8    Beals, B.9    Dykes, D.10    Noker, P.11    Yao, R.12    Labao, E.13    Hawkins, M.14    Soon-Shiong, P.15
  • 94
    • 35248847969 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes
    • 10.1016/j.clim.2007.07.018, 17827069
    • Gerlini G, Urso C, Mariotti G, Di Gennaro P, Palli D, Brandani P, Salvadori A, Pimpinelli N, Reali UM, Borgognoni L. Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes. Clin Immunol 2007, 125:184-193. 10.1016/j.clim.2007.07.018, 17827069.
    • (2007) Clin Immunol , vol.125 , pp. 184-193
    • Gerlini, G.1    Urso, C.2    Mariotti, G.3    Di Gennaro, P.4    Palli, D.5    Brandani, P.6    Salvadori, A.7    Pimpinelli, N.8    Reali, U.M.9    Borgognoni, L.10
  • 96
    • 84872688465 scopus 로고    scopus 로고
    • Dendritic cells recruitment in melanoma metastasis treated by electrochemotherapy
    • 10.1007/s10585-012-9505-1, 22735940
    • Gerlini G, Sestini S, Di Gennaro P, Urso C, Pimpinelli N, Borgognoni L. Dendritic cells recruitment in melanoma metastasis treated by electrochemotherapy. Clin Exp Metastasis 2013, 30:37-45. 10.1007/s10585-012-9505-1, 22735940.
    • (2013) Clin Exp Metastasis , vol.30 , pp. 37-45
    • Gerlini, G.1    Sestini, S.2    Di Gennaro, P.3    Urso, C.4    Pimpinelli, N.5    Borgognoni, L.6
  • 97
    • 84879156920 scopus 로고    scopus 로고
    • Enhancing anti-melanoma immunity by electrochemotherapy and in vivo dendritic-cell activation
    • 10.4161/onci.21991, 3525636, 23264927
    • Gerlini G, Di Gennaro P, Borgognoni L. Enhancing anti-melanoma immunity by electrochemotherapy and in vivo dendritic-cell activation. Oncoimmunology 2012, 1:1655-1657. 10.4161/onci.21991, 3525636, 23264927.
    • (2012) Oncoimmunology , vol.1 , pp. 1655-1657
    • Gerlini, G.1    Di Gennaro, P.2    Borgognoni, L.3
  • 98
    • 20644434717 scopus 로고    scopus 로고
    • Phase I study of hepatic arterial melphalan infusion and hepatic venous hemofiltration using percutaneouslyplaced catheters in patients with unresectable hepatic malignancies
    • 10.1200/JCO.2005.00.927, 2374756, 15908655
    • Pingpank JF, Libutti SK, Chang R, Wood BJ, Neeman Z, Kam AW, Figg WD, Zhai S, Beresneva T, Seidel GD, Alexander HR. Phase I study of hepatic arterial melphalan infusion and hepatic venous hemofiltration using percutaneouslyplaced catheters in patients with unresectable hepatic malignancies. J Clin Oncol 2005, 23:3465-3474. 10.1200/JCO.2005.00.927, 2374756, 15908655.
    • (2005) J Clin Oncol , vol.23 , pp. 3465-3474
    • Pingpank, J.F.1    Libutti, S.K.2    Chang, R.3    Wood, B.J.4    Neeman, Z.5    Kam, A.W.6    Figg, W.D.7    Zhai, S.8    Beresneva, T.9    Seidel, G.D.10    Alexander, H.R.11
  • 99
    • 79954601182 scopus 로고    scopus 로고
    • A phase III random assignment trial comparing percutaneous hepatic perfusion with melphalan (PHP-mel) to standard of care for patients with hepatic metastases from metastatic ocular or cutaneous melanoma [abstract]
    • abstr. LBA8512
    • Pingpank JF, Hughes MS, Faries MB, Zager JS, Alexander HR, Royal R, Whitman ED, Nutting CW, Siskin GP, Agarwala SS. A phase III random assignment trial comparing percutaneous hepatic perfusion with melphalan (PHP-mel) to standard of care for patients with hepatic metastases from metastatic ocular or cutaneous melanoma [abstract]. J Clin Oncol 2010, 28:18s. abstr. LBA8512.
    • (2010) J Clin Oncol , vol.28
    • Pingpank, J.F.1    Hughes, M.S.2    Faries, M.B.3    Zager, J.S.4    Alexander, H.R.5    Royal, R.6    Whitman, E.D.7    Nutting, C.W.8    Siskin, G.P.9    Agarwala, S.S.10
  • 100
    • 84856727864 scopus 로고    scopus 로고
    • Novel insights into molecular mechanisms of HLA class I abnormalities
    • 10.1007/s00262-011-1153-9, 22120755
    • Seliger B. Novel insights into molecular mechanisms of HLA class I abnormalities. Cancer Immunol Immunother 2012, 61:249-254. 10.1007/s00262-011-1153-9, 22120755.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 249-254
    • Seliger, B.1
  • 101
    • 79951549780 scopus 로고    scopus 로고
    • Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?
    • 10.1007/s00018-010-0583-4, 3426238, 21063893
    • Amiot L, Ferrone S, Grosse-Wilde H, Seliger B. Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?. Cell Mol Life Sci 2011, 68:417-431. 10.1007/s00018-010-0583-4, 3426238, 21063893.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 417-431
    • Amiot, L.1    Ferrone, S.2    Grosse-Wilde, H.3    Seliger, B.4
  • 103
    • 80053375190 scopus 로고    scopus 로고
    • Tumor-derived autophagosome vaccine: induction of cross-protective immuneresponses against short-lived proteins through a p62-dependent mechanism
    • 10.1158/1078-0432.CCR-11-0812, 3298078, 21810919
    • Twitty CG, Jensen SM, Hu HM, Fox BA. Tumor-derived autophagosome vaccine: induction of cross-protective immuneresponses against short-lived proteins through a p62-dependent mechanism. Clin Cancer Res 2011, 17:6467-6481. 10.1158/1078-0432.CCR-11-0812, 3298078, 21810919.
    • (2011) Clin Cancer Res , vol.17 , pp. 6467-6481
    • Twitty, C.G.1    Jensen, S.M.2    Hu, H.M.3    Fox, B.A.4
  • 106
    • 78449251207 scopus 로고    scopus 로고
    • Clinical studies with anti-CTLA-4 antibodies in non-melanoma indications
    • 10.1053/j.seminoncol.2010.09.006, 21074061
    • Calabrò L, Danielli R, Sigalotti L, Maio M. Clinical studies with anti-CTLA-4 antibodies in non-melanoma indications. Semin Oncol 2010, 37:460-467. 10.1053/j.seminoncol.2010.09.006, 21074061.
    • (2010) Semin Oncol , vol.37 , pp. 460-467
    • Calabrò, L.1    Danielli, R.2    Sigalotti, L.3    Maio, M.4
  • 111
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • 10.1038/nrc3245, 22419253
    • Fridman WH, Pages F, Sautes-Fridman C, Galon J. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 2012, 12:298-306. 10.1038/nrc3245, 22419253.
    • (2012) Nat Rev Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4


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