-
1
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al: Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 364:2507-2516, 2011
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
2
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, et al: Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 364:2517-2526, 2011
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
3
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al: Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363:711-723, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
4
-
-
0036717864
-
+ patients with renal cell carcinoma or melanoma
-
DOI 10.1084/jem.20012142
-
Tatsumi T, Kierstead LS, Ranieri E, et al: Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma. J Exp Med 196:619-628, 2002 (Pubitemid 35024440)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.5
, pp. 619-628
-
-
Tatsumi, T.1
Kierstead, L.S.2
Ranieri, E.3
Gesualdo, L.4
Schena, F.P.5
Finke, J.H.6
Bukowski, R.M.7
Mueller-Berghaus, J.8
Kirkwood, J.M.9
Kwok, W.W.10
Storkus, W.J.11
-
5
-
-
0033759463
-
The critical role of Th1-dominant immunity in tumor immunology
-
Nishimura T, Nakui M, Sato M, et al: The critical role of Th1-dominant immunity in tumor immunology. Cancer Chemother Pharmacol 46:S52-S61, 2000 (suppl)
-
(2000)
Cancer Chemother Pharmacol
, vol.46
, Issue.SUPPL.
-
-
Nishimura, T.1
Nakui, M.2
Sato, M.3
-
6
-
-
0030030347
-
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group trial EST 1684
-
Kirkwood JM, Strawderman MH, Ernstoff MS, et al: Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol 14:7-17, 1996 (Pubitemid 26019991)
-
(1996)
Journal of Clinical Oncology
, vol.14
, Issue.1
, pp. 7-17
-
-
Kirkwood, J.M.1
Strawderman, M.H.2
Ernstoff, M.S.3
Smith, T.J.4
Borden, E.C.5
Blum, R.H.6
-
7
-
-
0036720445
-
Immunomodulatory effects of high-dose and low-dose interferon alpha2b in patients with high-risk resected melanoma: The E2690 Laboratory Corollary of Intergroup Adjuvant Trial E1690
-
DOI 10.1002/cncr.10775
-
Kirkwood JM, Richards T, Zarour HM, et al: Immunomodulatory effects of high-dose and low-dose interferon alpha2b in patients with high-risk resected melanoma: The E2690 laboratory corollary of intergroup adjuvant trial E1690. Cancer 95:1101-1112, 2002 (Pubitemid 34925363)
-
(2002)
Cancer
, vol.95
, Issue.5
, pp. 1101-1112
-
-
Kirkwood, J.M.1
Richards, T.2
Zarour, H.M.3
Sosman, J.4
Ernstoff, M.5
Whiteside, T.L.6
Ibrahim, J.7
Blum, R.8
Wieand, S.9
Mascari, R.10
-
8
-
-
33947423447
-
Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b
-
DOI 10.1158/1078-0432.CCR-06-1387
-
Wang W, Edington HD, Rao UN, et al: Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b. Clin Cancer Res 13:1523-1531, 2007 (Pubitemid 46450444)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.5
, pp. 1523-1531
-
-
Wang, W.1
Edington, H.D.2
Rao, U.N.M.3
Jukic, D.M.4
Land, S.R.5
Ferrone, S.6
Kirkwood, J.M.7
-
9
-
-
0031656896
-
Interferon-alpha and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells
-
Paquette RL, Hsu NC, Kiertscher SM, et al: Interferon-alpha and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells. J Leukoc Biol 64:358-367, 1998 (Pubitemid 28409243)
-
(1998)
Journal of Leukocyte Biology
, vol.64
, Issue.3
, pp. 358-367
-
-
Paquette, R.L.1
Hsu, N.C.2
Kiertscher, S.M.3
Park, A.N.4
Tran, L.5
Roth, M.D.6
Glaspy, J.A.7
-
10
-
-
17644449715
-
Expression of CCR-7, MIP-3beta, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: Importance for the rapid acquisition of potent migratory and functional activities
-
Parlato S, Santini SM, Lapenta C, et al: Expression of CCR-7, MIP-3beta, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: Importance for the rapid acquisition of potent migratory and functional activities Blood 98:3022-3029, 2001
-
(2001)
Blood
, vol.98
, pp. 3022-3029
-
-
Parlato, S.1
Santini, S.M.2
Lapenta, C.3
-
11
-
-
0027433104
-
+ T cells
-
DOI 10.1084/jem.178.5.1655
-
Brinkmann V, Geiger T, Alkan S, et al: Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells. J Exp Med 178:1655-1663, 1993 (Pubitemid 23318444)
-
(1993)
Journal of Experimental Medicine
, vol.178
, Issue.5
, pp. 1655-1663
-
-
Brinkmann, V.1
Geiger, T.2
Alkan, S.3
Heusser, C.H.4
-
12
-
-
0029671118
-
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development
-
Wenner CA, Güler ML, Macatonia SE, et al: Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development. J Immunol 156:1442-1447, 1996
-
(1996)
J Immunol
, vol.156
, pp. 1442-1447
-
-
Wenner, C.A.1
Güler, M.L.2
Macatonia, S.E.3
-
13
-
-
0030892136
-
Selective expression of an interleukin-12 receptor component by human T helper 1 cells
-
DOI 10.1084/jem.185.5.825
-
Rogge L, Barberis-Maino L, Biffi M, et al: Selective expression of an interleukin-12 receptor component by human T helper 1 cells. J Exp Med 185:825-831, 1997 (Pubitemid 27119866)
-
(1997)
Journal of Experimental Medicine
, vol.185
, Issue.5
, pp. 825-831
-
-
Rogge, L.1
Barberis-Maino, L.2
Biffi, M.3
Passini, N.4
Presky, D.H.5
Gubler, U.6
Sinigaglia, F.7
-
14
-
-
0034020397
-
Interferon-alpha (IFN-alpha) stimulates anti-melanoma cytotoxic T lymphocyte (CTL) generation in mixed lymphocyte turnout cultures (MLTC)
-
Palmer KJ, Harries M, Gore ME, et al: Interferon-alpha (IFN-alpha) stimulates anti-melanoma cytotoxic T lymphocyte (CTL) generation in mixed lymphocyte tumour cultures (MLTC). Clin Exp Immunol 119:412-418, 2000 (Pubitemid 30146335)
-
(2000)
Clinical and Experimental Immunology
, vol.119
, Issue.3
, pp. 412-418
-
-
Palmer, K.J.1
Harries, M.2
Gore, M.E.3
Collins, M.K.L.4
-
15
-
-
0027290546
-
Interferon-alpha-2b enhances the natural killer activity of patients with transitional cell carcinoma of the bladder
-
Carballido JA, Moltó LM, Manzano L, et al: Interferon-alpha-2b enhances the natural killer activity of patients with transitional cell carcinoma of the bladder. Cancer 72:1743-1748, 1993 (Pubitemid 23249305)
-
(1993)
Cancer
, vol.72
, Issue.5
, pp. 1743-1748
-
-
Carballido, J.A.1
Molto, L.M.2
Manzano, L.3
Olivier, C.4
Salmeron, O.I.5
De Mon, M.A.6
-
16
-
-
34247868145
-
Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b
-
DOI 10.1158/1078-0432.CCR-06-1805
-
Yurkovetsky ZR, Kirkwood JM, Edington HD, et al: Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b. Clin Cancer Res 13:2422-2428, 2007 (Pubitemid 46698593)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.8
, pp. 2422-2428
-
-
Yurkovetsky, Z.R.1
Kirkwood, J.M.2
Edington, H.D.3
Marrangoni, A.M.4
Velikokhatnaya, L.5
Winans, M.T.6
Gorelik, E.7
Lokshin, A.E.8
-
17
-
-
0842301509
-
Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation
-
Tough DF: Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation. Leuk Lymphoma 45:257-264, 2004
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 257-264
-
-
Tough, D.F.1
-
18
-
-
33745989541
-
Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses
-
DOI 10.1200/JCO.2005.05.2498
-
Moschos SJ, Edington HD, Land SR, et al: Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses. J Clin Oncol 24:3164-3171, 2006 (Pubitemid 46638955)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.19
, pp. 3164-3171
-
-
Moschos, S.J.1
Edington, H.D.2
Land, S.R.3
Rao, U.N.4
Jukic, D.5
Shipe-Spotloe, J.6
Kirkwood, J.M.7
-
19
-
-
0023270567
-
A new member of the immunoglobulin superfamily-CTLA-4
-
Brunet JF, Denizot F, Luciani MF, et al: A new member of the immunoglobulin superfamily-CTLA-4. Nature 328:267-270, 1987
-
(1987)
Nature
, vol.328
, pp. 267-270
-
-
Brunet, J.F.1
Denizot, F.2
Luciani, M.F.3
-
20
-
-
0033563265
-
Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses
-
Khattri R, Auger JA, Griffin MD, et al: Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses. J Immunol 162:5784-5791, 1999 (Pubitemid 29314929)
-
(1999)
Journal of Immunology
, vol.162
, Issue.10
, pp. 5784-5791
-
-
Khattri, R.1
Auger, J.A.2
Griffin, M.D.3
Sharpe, A.H.4
Bluestone, J.A.5
-
21
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol EA, Borriello F, Schweitzer AN, et al: Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541-547, 1995
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
-
22
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P, Penninger JM, Timms E, et al: Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270:985-988, 1995
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
23
-
-
0032490620
-
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28
-
DOI 10.1084/jem.188.1.199
-
Lin H, Rathmell JC, Gray GS, et al: Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. J Exp Med 188:199-204, 1998 (Pubitemid 28328618)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.1
, pp. 199-204
-
-
Lin, H.1
Rathmell, J.C.2
Gray, G.S.3
Thompson, C.B.4
Leiden, J.M.5
Alegre, M.-L.6
-
24
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel MF, Allison JP: CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 182:459-465, 1995
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
25
-
-
0034194329
-
Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade
-
Hurwitz AA, Foster BA,**Kwon ED, et al: Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade. Cancer Res 60(9):2444-2448, 2000 (Pubitemid 30262435)
-
(2000)
Cancer Research
, vol.60
, Issue.9
, pp. 2444-2448
-
-
Hurwitz, A.A.1
Foster, B.A.2
Kwon, E.D.3
Truong, T.4
Choi, E.M.5
Greenberg, N.M.6
Burg, M.B.7
Allison, J.P.8
-
26
-
-
0033592924
-
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
-
DOI 10.1073/pnas.96.26.15074
-
Kwon ED, Foster BA, Hurwitz AA, et al: Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy. Proc Natl Acad Sci U S A 96:15074-15079, 1999 (Pubitemid 30019767)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.26
, pp. 15074-15079
-
-
Kwon, E.D.1
Foster, B.A.2
Hurwitz, A.A.3
Madias, C.4
Allison, J.P.5
Greenberg, N.M.6
Burg, M.B.7
-
27
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony- stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
DOI 10.1084/jem.190.3.355
-
van Elsas A, Hurwitz AA, Allison JP: Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 190:355-366, 1999 (Pubitemid 29374833)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.3
, pp. 355-366
-
-
Van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
28
-
-
33846892181
-
Preclinical in vitro characterization of anti-CTLA4 therapeutic antibody CP-675,206
-
abstr 3802
-
Hanson DC, Canniff PC, Primiano MJ, et al: Preclinical in vitro characterization of anti-CTLA4 therapeutic antibody CP-675,206. Proc Am Assoc Cancer Res 45, 2004 (abstr 3802)
-
(2004)
Proc Am Assoc Cancer Res
, vol.45
-
-
Hanson, D.C.1
Canniff, P.C.2
Primiano, M.J.3
-
29
-
-
84856075104
-
Changes in intratumoral immune cell infiltrates, Foxp3 and indoleamine 2, 3-dioxygenase (IDO) expression with the CTLA4 blocking MAB CP-675,206
-
Ribas A, DT, Comin-Anduix B, de la Rocha P, et al: Changes in intratumoral immune cell infiltrates, Foxp3 and indoleamine 2, 3-dioxygenase (IDO) expression with the CTLA4 blocking MAB CP-675,206. J Immunother 29:636, 2006
-
(2006)
J Immunother
, vol.29
, pp. 636
-
-
Ribas, A.1
D, T.2
Comin-Anduix, B.3
De La Rocha, P.4
-
30
-
-
0036727090
-
Mechanisms and management of toxicities associated with high-dose interferon alfa-2b therapy
-
DOI 10.1200/JCO.2002.03.052
-
Kirkwood JM, Bender C, Agarwala S, et al: Mechanisms and management of toxicities associated with high-dose interferon alfa-2b therapy. J Clin Oncol 20:3703-3718, 2002 (Pubitemid 34983231)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.17
, pp. 3703-3718
-
-
Kirkwood, J.M.1
Bender, C.2
Agarwala, S.3
Tarhini, A.4
Shipe-Spotloe, J.5
Smelko, B.6
Donnelly, S.7
Stover, L.8
-
31
-
-
39749104201
-
Practical guidelines for the management of interferon-alpha-2b side effects in patients receiving adjuvant treatment for melanoma: Expert opinion
-
DOI 10.1002/cncr.23251
-
Hauschild A, Gogas H, Tarhini A, et al: Practical guidelines for the management of interferon-alpha-2b side effects in patients receiving adjuvant treatment for melanoma: Expert opinion. Cancer 112:982-994, 2008 (Pubitemid 351304581)
-
(2008)
Cancer
, vol.112
, Issue.5
, pp. 982-994
-
-
Hauschild, A.1
Gogas, H.2
Tarhini, A.3
Middleton, M.R.4
Testori, A.5
Dreno, B.6
Kirkwood, J.M.7
-
32
-
-
39149104690
-
Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials
-
DOI 10.1200/JCO.2007.12.7837
-
Korn EL, Liu PY, Lee SJ, et al: Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. J Clin Oncol 26:527-534, 2008 (Pubitemid 351264344)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 527-534
-
-
Korn, E.L.1
Liu, P.-Y.2
Lee, S.J.3
Chapman, J.-A.W.4
Niedzwiecki, D.5
Suman, V.J.6
Moon, J.7
Sondak, V.K.8
Atkins, M.B.9
Eisenhauer, E.A.10
Parulekar, W.11
Markovic, S.N.12
Saxman, S.13
Kirkwood, J.M.14
-
33
-
-
54349094280
-
Tremelimumab (CP-675,206): A fully human anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody for treatment of patients with advanced cancers
-
Tarhini AA, Kirkwood JM: Tremelimumab (CP-675,206): A fully human anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody for treatment of patients with advanced cancers. Expert Opin Biol Ther 8:1583-1593, 2008
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 1583-1593
-
-
Tarhini, A.A.1
Kirkwood, J.M.2
-
34
-
-
78649237899
-
Evaluation of baseline serum C-reactive protein (CRP) and benefit from tremelimumab compared to chemotherapy in first-line melanoma
-
abstr 2609
-
Marshall M, Ribas A, Huang B: Evaluation of baseline serum C-reactive protein (CRP) and benefit from tremelimumab compared to chemotherapy in first-line melanoma. J Clin Oncol 28:231s, 2010 (abstr 2609)
-
(2010)
J Clin Oncol
, vol.28
-
-
Marshall, M.1
Ribas, A.2
Huang, B.3
-
35
-
-
59149090272
-
Antitumor response and new lesions in advanced melanoma patients on ipilimumab treatment
-
abstr 3020
-
Wolchok JD, Ibrahim R, DePril V, et al: Antitumor response and new lesions in advanced melanoma patients on ipilimumab treatment. J Clin Oncol 26:137s, 2008 (suppl; abstr 3020)
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Wolchok, J.D.1
Ibrahim, R.2
DePril, V.3
-
36
-
-
61449159816
-
A phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma
-
abstr 9023
-
Kirkwood JM, Lorigan P, Hersey P, et al: A phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma. J Clin Oncol 26:488s, 2008 (suppl; abstr 9023)
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Kirkwood, J.M.1
Lorigan, P.2
Hersey, P.3
-
37
-
-
55949137090
-
Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma
-
abstr LBA9011
-
Ribas A, Hauschild A, Kefford R, et al: Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma. J Clin Oncol 26:485s, 2008 (suppl; abstr LBA9011)
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Ribas, A.1
Hauschild, A.2
Kefford, R.3
-
38
-
-
32644454916
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
DOI 10.1056/NEJMoa053007
-
Gogas H, Ioannovich J, Dafni U, et al: Prognostic significance of autoimmunity during treatment of melanoma with interferon. N Engl J Med 354:709-718, 2006 (Pubitemid 43247141)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.7
, pp. 709-718
-
-
Gogas, H.1
Ioannovich, J.2
Dafni, U.3
Stavropoulou-Giokas, C.4
Frangia, K.5
Tsoutsos, D.6
Panagiotou, P.7
Polyzos, A.8
Papadopoulos, O.9
Stratigos, A.10
Markopoulos, C.11
Bafaloukos, D.12
Pectasides, D.13
Fountzilas, G.14
Kirkwood, J.M.15
-
39
-
-
84855719516
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
Krauze MT, Tarhini A, Gogas H, et al: Prognostic significance of autoimmunity during treatment of melanoma with interferon. Semin Immunopathol 33:385-391, 2011
-
(2011)
Semin Immunopathol
, vol.33
, pp. 385-391
-
-
Krauze, M.T.1
Tarhini, A.2
Gogas, H.3
-
40
-
-
0023888654
-
Hypothyroidism after treatment with interleukin-2 and lymphokine-activated killer cells
-
Atkins MB, Mier JW, Parkinson DR, et al: Hypothyroidism after treatment with interleukin-2 and lymphokine-activated killer cells. N Engl J Med 318:1557-1563, 1988
-
(1988)
N Engl J Med
, vol.318
, pp. 1557-1563
-
-
Atkins, M.B.1
Mier, J.W.2
Parkinson, D.R.3
-
41
-
-
0027245920
-
Hypothyroidism during immunotherapy with interleukin-2 is associated with antithyroid antibodies and response to treatment
-
Weijl NI, van der Harst D, Brand A, et al: Hypothyroidism during immunotherapy with interleukin-2 is associated with antithyroid antibodies and response to treatment. J Clin Oncol 11:1376-1383, 1993 (Pubitemid 23199144)
-
(1993)
Journal of Clinical Oncology
, vol.11
, Issue.7
, pp. 1376-1383
-
-
Weijl, N.I.1
Van Der, H.D.2
Brand, A.3
Kooy, Y.4
Van Luxemburg, S.5
Schroder, J.6
Lentjes, E.7
Van Rood, J.J.8
Cleton, F.J.9
Osanto, S.10
-
42
-
-
0025641296
-
Primary hypothyroidism associated with interleukin-2 and interferon alpha-2 therapy of melanoma and renal carcinoma
-
Scalzo S, Gengaro A, Boccoli G, et al: Primary hypothyroidism associated with interleukin-2 and interferon alpha-2 therapy of melanoma and renal carcinoma. Eur J Cancer 26:1152-1156, 1990
-
(1990)
Eur J Cancer
, vol.26
, pp. 1152-1156
-
-
Scalzo, S.1
Gengaro, A.2
Boccoli, G.3
-
43
-
-
0029550054
-
Thyroid dysfunction in 281 patients with metastatic melanoma or renal carcinoma treated with interleukin-2 alone
-
Krouse RS, Royal RE, Heywood G, et al: Thyroid dysfunction in 281 patients with metastatic melanoma or renal carcinoma treated with interleukin-2 alone. J Immunother Emphasis Tumor Immunol 18:272-278, 1995 (Pubitemid 26089626)
-
(1995)
Journal of Immunotherapy
, vol.18
, Issue.4
, pp. 272-278
-
-
Krouse, R.S.1
Royal, R.E.2
Heywood, G.3
Weintraub, B.D.4
White, D.E.5
Steinberg, S.M.6
Rosenberg, S.A.7
Schwartzentruber, D.J.8
-
44
-
-
0035425425
-
Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma
-
Phan GQ, Attia P, Steinberg SM, et al: Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma. J Clin Oncol 19:3477-3482, 2001 (Pubitemid 32730084)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.15
, pp. 3477-3482
-
-
Phan, G.Q.1
Attia, P.2
Steinberg, S.M.3
White, D.E.4
Rosenberg, S.A.5
-
45
-
-
0028205754
-
Antiphospholipid syndrome associated with immunotherapy for patients with melanoma
-
Becker JC, Winkler B, Klingert S, et al: Antiphospholipid syndrome associated with immunotherapy for patients with melanoma. Cancer 73(6):1621-1624, 1994 (Pubitemid 24085261)
-
(1994)
Cancer
, vol.73
, Issue.6
, pp. 1621-1624
-
-
Becker, J.C.1
Winkler, B.2
Klingert, S.3
Brocker, E.-B.4
-
46
-
-
0030008301
-
Vitiligo in patients with melanoma: Normal tissue antigens can be targets for cancer immunotherapy
-
DOI 10.1097/00002371-199601000-00009
-
Rosenberg SA, White DE: Vitiligo in patients with melanoma: Normal tissue antigens can be targets for cancer immunotherapy. J Immunother Emphasis Tumor Immunol 19:81-84, 1996 (Pubitemid 26127369)
-
(1996)
Journal of Immunotherapy
, vol.19
, Issue.1
, pp. 81-84
-
-
Rosenberg, S.A.1
White, D.E.2
-
47
-
-
0033014677
-
Autoimmunity resulting from cytokine treatment predicts long-term survival in patients with metastatic renal cell cancer
-
Franzke A, Peest D, Probst-Kepper M, et al: Autoimmunity resulting from cytokine treatment predicts long-term survival in patients with metastatic renal cell cancer. J Clin Oncol 17:529-533, 1999 (Pubitemid 29075239)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.2
, pp. 529-533
-
-
Franzke, A.1
Peest, D.2
Probst-Kepper, M.3
Buer, J.4
Kirchner, G.I.5
Brabant, G.6
Kirchner, H.7
Ganser, A.8
Atzpodien, J.9
-
48
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
DOI 10.1073/pnas.1533209100
-
Phan GQ, Yang JC, Sherry RM, Hwu P, et al: Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A 100:8372-8377, 2003 (Pubitemid 36842552)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
Hwu, P.4
Topalian, S.L.5
Schwartzentruber, D.J.6
Restifo, N.P.7
Haworth, L.R.8
Seipp, C.A.9
Freezer, L.J.10
Morton, K.E.11
Mavroukakis, S.A.12
Duray, P.H.13
Steinberg, S.M.14
Allison, J.P.15
Davis, T.A.16
Rosenberg, S.A.17
-
49
-
-
20044395957
-
Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and montanide ISA 51 for patients with resected stages III and IV melanoma
-
DOI 10.1200/JCO.2005.01.128
-
Sanderson K, Scotland R, Lee P, et al: Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma. J Clin Oncol 23:741-750, 2005 (Pubitemid 46224173)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 741-750
-
-
Sanderson, K.1
Scotland, R.2
Lee, P.3
Liu, D.4
Groshen, S.5
Snively, J.6
Sian, S.7
Nichol, G.8
Davis, T.9
Keler, T.10
Yellin, M.11
Weber, J.12
-
50
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
Dranoff G, Jaffee E, Lazenby A, et al: Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A, 90:3539-3543, 1993 (Pubitemid 23111402)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.8
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
Jackson, V.7
Hamada, H.8
Pardoll, D.9
Mulligan, R.C.10
-
51
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
DOI 10.1200/JCO.2005.01.109
-
Ribas A, Camacho LH, Lopez-Berestein, et al: Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol, 23:8968-8977, 2005 (Pubitemid 46217464)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.35
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
Pavlov, D.4
Bulanhagui, C.A.5
Millham, R.6
Comin-Anduix, B.7
Reuben, J.M.8
Seja, E.9
Parker, C.A.10
Sharma, A.11
Glaspy, J.A.12
Gomez-Navarro, J.13
-
52
-
-
37049002728
-
Interferon alfa-induced autoimmunity and serum S100 levels as predictive and prognostic biomarkers in high-risk melanoma in the ECOG-intergroup phase II trial E2696
-
abstr 8506
-
Stuckert JJ, Tarhini AA, Lee S, et al: Interferon alfa-induced autoimmunity and serum S100 levels as predictive and prognostic biomarkers in high-risk melanoma in the ECOG-intergroup phase II trial E2696. J Clin Oncol 25:473s, 2007 (suppl; abstr 8506)
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Stuckert, J.J.1
Tarhini, A.A.2
Lee, S.3
-
53
-
-
4344701616
-
Diagnosing melanoma patients entering American Joint Committee on Cancer stage IV, C-reactive protein in serum is superior to lactate dehydrogenase
-
Deichmann M, Kahle B, Moser K, et al: Diagnosing melanoma patients entering American Joint Committee on Cancer stage IV, C-reactive protein in serum is superior to lactate dehydrogenase. Br J Cancer 91:699-702, 2004 (Pubitemid 39141627)
-
(2004)
British Journal of Cancer
, vol.91
, Issue.4
, pp. 699-702
-
-
Deichmann, M.1
Kahle, B.2
Moser, K.3
Wacker, J.4
Wust, K.5
-
54
-
-
26044483536
-
C-reactive protein: Ligands, receptors and role in inflammation
-
DOI 10.1016/j.clim.2005.08.004, PII S1521661605002809
-
Marnell L, Mold C, Du Clos TW: C-reactive protein: Ligands, receptors and role in inflammation. Clin Immunol 117:104-111, 2005 (Pubitemid 41407719)
-
(2005)
Clinical Immunology
, vol.117
, Issue.2
, pp. 104-111
-
-
Marnell, L.1
Mold, C.2
Du, C.T.W.3
-
55
-
-
73249115405
-
Interferon-alpha mediates suppression of C-reactive protein: Explanation for muted C-reactive protein response in lupus flares?
-
Enocsson H, Sjöwall C, Skogh T, et al: Interferon-alpha mediates suppression of C-reactive protein: Explanation for muted C-reactive protein response in lupus flares? Arthritis Rheum 60:3755-3760, 2009
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3755-3760
-
-
Enocsson, H.1
Sjöwall, C.2
Skogh, T.3
-
56
-
-
77955253357
-
Association of baseline and on-study tumor biopsy markers with clinical activity in patients (pts) with advanced melanoma treated with ipilimumab
-
abstr 9008
-
Hamid O, Chasalow SD, Tsuchihashi Z, et al: Association of baseline and on-study tumor biopsy markers with clinical activity in patients (pts) with advanced melanoma treated with ipilimumab. J Clin Oncol 27:463s, 2009 (suppl; abstr 9008)
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Hamid, O.1
Chasalow, S.D.2
Tsuchihashi, Z.3
-
57
-
-
55949133643
-
Dose effect of ipilimumab in patients with advanced melanoma: Results from a phase II, randomized, dose-ranging study
-
abstr 9025
-
Hamid O: Dose effect of ipilimumab in patients with advanced melanoma: Results from a phase II, randomized, dose-ranging study. J Clin Oncol 26:489s, 2008 (suppl; abstr 9025)
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Hamid, O.1
-
58
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study
-
Wolchok JD, Neyns B, Linette G, et al: Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 11:155-164, 2010
-
(2010)
Lancet Oncol
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
-
59
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S: Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162-174, 2009
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
60
-
-
34547655923
-
+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment
-
DOI 10.1158/1078-0432.CCR-07-0472
-
Strauss L, Bergmann C, Szczepanski M, et al: A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment. Clin Cancer Res 13:4345-4354, 2007 (Pubitemid 47219698)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.15
, pp. 4345-4354
-
-
Strauss, L.1
Bergmann, C.2
Szczepanski, M.3
Gooding, W.4
Johnson, J.T.5
Whiteside, T.L.6
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