SCOPUS 정보 검색 플랫폼

ChemMedChem

Volumn 8, Issue 6, 2013, Pages 1002-1011

Synthesis and Evaluation of Water-Soluble Prodrugs of Ursodeoxycholic Acid (UDCA), an Anti-apoptotic Bile Acid

(5) Dosa, Peter I a Ward, Tim a Castro, Rui E b Rodrigues, Cecília M P b Steer, Clifford J c

a UNIVERSITY OF MINNESOTA (United States)

b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA (Portugal)

c UNIVERSITY OF MINNESOTA (United States)

Author keywords

Apoptosis; Bile acids; Phosphoryloxymethyl carboxylate; Prodrugs; Ursodeoxycholic acid

Indexed keywords

3 (BENZYLOXYCARBONYLOXY) 7 (CHLOROMETHOXY)URSODEOXYCHOLIC ACID BENZYL ESTER; 3 (BENZYLOXYCARBONYLOXY) 7 (METHYLTHIOMETHOXY)URSODEOXYCHOLIC ACID BENZYL ESTER; 3 (BENZYLOXYCARBONYLOXY) 7[BIS(BENZYLOXY)PHOSPHORYLOXY]URSODEOXYCHOLIC ACID BENZYL ESTER; 3 (BENZYLOXYCARBONYLOXY)URSODEOXYCHOLIC ACID BENZYL ESTER; 3 (CHLOROMETHOXY) 7 (BENZYLOXYCARBONYLOXY)URSODEOXYCHOLIC ACID BENZYL ESTER; 3 (METHYLTHIOMETHOXY) 7 (BENZYLOXYCARBONYLOXY)URSODEOXYCHOLIC ACID BENZYL ESTER; 3 (PHOSPHONATOOXY)URSODEOXYCHOLIC ACID SODIUM SALT; 3 (PHOSPHONOOXYMETHOXY)URSODEOXYCHOLIC ACID TRIBUTYLAMINE SALT; 3 [BIS(BENZYLOXY)PHOSPHORYLOXY]URSODEOXYCHOLIC ACID BENZYL ESTER; 7 (BENZYLOXYCARBONYLOXY)URSODEOXYCHOLIC ACID BENZYL ESTER; 7 (PHOSPHONATOOXY)URSODEOXYCHOLIC ACID SODIUM SALT; 7 (PHOSPHONOOXYMETHOXY)URSODEOXYCHOLIC ACID SODIUM SALT; 7 (PHOSPHONOOXYMETHOXY)URSODEOXYCHOLIC ACID TRIBUTYLAMINE SALT; ALKALINE PHOSPHATASE; CASPASE 3; PRODRUG; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID [BIS(BENZYLOXY)PHOSPHORYLOXY]METHYL ESTER; URSODEOXYCHOLIC ACID BENZYL ESTER; URSODEOXYCHOLIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; IN VITRO STUDY; LIVER CELL; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PUMMERER REACTION; RAT;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; MALE; MOLECULAR CONFORMATION; PRODRUGS; RATS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFORMING GROWTH FACTOR BETA1; URSODEOXYCHOLIC ACID; WATER;

EID: 84878372256 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201300059 Document Type: Article

Times cited : (27)

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