Ro 32-0432 attenuates mecamylamine-precipitated nicotine withdrawal syndrome in mice

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 3, 2013, Pages 197-204

  Singh, Thakur Gurjeet ^a   Rehni, Ashish K ^a   Arora, Sandeep ^a  

^a CHITKARA UNIVERSITY   (India)

Author keywords

G protein coupled receptor kinase 5; Nicotine dependence; Ro 32 0432; Withdrawal syndrome

Indexed keywords

3 [8 [(DIMETHYLAMINO)METHYL] 6,7,8,9 TETRAHYDROPYRIDO[1,2 A]INDOL 10 YL] 4 (1 METHYL 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE; MECAMYLAMINE; NICOTINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HYPERALGESIA; JUMPING; MALE; MAZE TEST; MOUSE; NONHUMAN; TAIL FLICK TEST; TOBACCO DEPENDENCE; WITHDRAWAL SYNDROME;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; G-PROTEIN-COUPLED RECEPTOR KINASE 5; INDOLES; MALE; MAZE LEARNING; MECAMYLAMINE; MICE; NICOTINE; PYRROLES; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84878358350     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0825-0     Document Type: Article

References (44)

1. American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders. American Psychiatric Press, Washington, DC
2. Arriza JL, Dawson TM, Simerly RB, Martin LJ, Caron MG, Snyder SH, Lefkowitz RJ (1992) The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain. J Neurosci 12:4045-4055
3. Balfour DJ (2004) The neurobiology of tobacco dependence: a preclinical perspective on the role of the dopamine projections to the nucleus accumbens. Nicotine Tob Res 6(6):899-912
4. Berrettini WH, Lerman CE (2005) Pharmacotherapy and pharmacogenetic of nicotine dependence. Am J Psychiatry 162:1441-1451
5. Biala G, Weglinska B (2005) Blockade of the expression of mecamylamine-precipitated nicotine withdrawal by calcium channel antagonists. Pharmacol Res 51:483-488
6. Bibevski S, Zhou Y, McIntosh JM, Zigmond RE, Dunlap ME (2000) Functional nicotinic acetylcholine receptors that mediate ganglionic transmission in cardiac parasympathetic neurons. J Neurosci 20:5076-5082
7. Brown RA, Kahler CW, Zvolensky MJ, Lejuez CW, Ramsey SE (2001) Anxiety sensitivity: relationship to negative affect smoking and smoking cessation in smokers with past major depressive disorder. Addict Behav 26(6):887-899
8. Carey MP, Carey MP, Kalra DL, Carey KB, Halperin S, Richards CS (1993) Stress and unaided smoking cessation: a prospective investigation. J Consult Clin Psychol 61(5):831-838
9. Cho D, Zheng M, Min C, Ma L, Kurose H, Park JH, Kim KM (2010) Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D(2) receptors. Mol Endocrinol 24(3):574-586
10. Damaj MI, Kao W, Martin BR (2003) Characterization of spontaneous and precipitated nicotine withdrawal in the mouse. J Pharmacol Exp Ther 307:526-534
11. D'Amour FE, Smith DL (1941) A method for determining loss of pain sensation. J Pharmacol Exp Ther 72:74-79
12. Dautzenberg FM, Kilpatrick GJ, Wille S, Hauger RL (1999) The ligand selective domains of corticotropin-releasing factor receptor type 1 and type 2 reside in different extracellular domains: generation of chimeric receptors with a novel ligand selective profile. J Neurochem 73:821-829
13. Dautzenberg FM, Braun S, Hauger RL (2001) GRK3 mediates desensitization of CRF1 receptors: a potential mechanism regulating stress adaptation. Am J Physiol Regul Integr Comp Physiol 280(4):R935-R946
14. Erdtmann-Vourliotis M, Mayer P, Ammon S et al (2001) Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5, and 6 mRNA in the rat brain. Mol Brain Res 95:129-137
15. Ferguson SS, Barak LS, Zhang J, Caron MG (1996) G-protein coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins. Can J Physiol Pharmacol 74:1095-1110
16. George O, Ghozland S, Azar MR, Cottone P, Zorrilla EP, Parsons LH et al (2007) CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats. Proc Natl Acad Sci U S A 104:17198-17203
17. Hauger RL, Dautzenberg FM (1999a) CRF receptor desensitization and phosphorylation: GRKs, PKC, and PKA. Brain Res 848:A26
18. Hauger RL, Dautzenberg FM (1999b) Regulation of the stress response by corticotropin-releasing factor receptors. In: Conn PM, Freeman ME (eds) Neuroendocrinology in physiology and medicine. Humana, Totowa, pp 261-286
19. Hauger RL, Risbrough V, Oakley RH, Olivares-Reyes JA, Dautzenberg FM (2009) Role of CRF receptor signaling in stress vulnerability, anxiety, and depression. Ann N Y Acad Sci 1179:120-143
20. Hildebrand BE, Nomikos GG, Hertel P, Schilström B, Svensson TH (1998) Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Brain Res 779(1-2):214-225
21. Ikemoto S, Panksepp J (1999) The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Brain Res Rev 31:6-41
22. Jackson KJ, Carroll FI, Negus SS, Damaj MI (2010) Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse. Psychopharmacology 210(2):285-294
23. Kiguchi N, Maeda T, Tsuruga M, Yamamoto A, Yamamoto C, Ozaki M, Kishioka S (2008) Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice. Brain Res 16(1189):70-77
24. Koob GF (2010) The role of CRF and CRF-related peptides in the dark side of addiction. Brain Res 1314:3-14
25. Koob GF, Le Moal M (2008) Addiction and the brain antireward system. Annu Rev Psychol 59:29-53
26. Koob GF, Volkow ND (2010) Neurocircuitry of addiction. Neuropsychopharmacology 35(1):217-238
27. Le Foll B, Goldberg SR (2009) Effects of nicotine in experimental animals and humans: an update on addictive properties. Handb Exp Pharmacol 192:335-367
28. Lemos JC, Wanat MJ, Smith JS, Reyes BA, Hollon NG, Van Bockstaele EJ, Chavkin C, Phillips PE (2012) Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. Nature 1490(7420):402-406
29. Liu DM, Cuevas J, Adams DJ (2000) VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation. Eur J Neurosci 12:2243-2251
30. Mifsud JC, Hernandez L, Hoebel BG (1989) Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain Res 478(2):365-367
31. Moore JB et al (1998) Inhibition of PTH desensitization by inhibition of the G protein-coupled receptor kinase-5 enzyme with Ro 32-0432. FASEB J 12:A741
32. Naha N, Lee HY, Hwang JS, Bahk JY, Park MS, Lee SY et al (2009) Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D(2) receptor and tyrosine hydroxylase expression. Neurol Res 31:289-299
33. Navarro JF, Buron E, Martin-Lopez M (2006) Anxiolytic-like activity of SB-205384 in the elevated plus maze test in mice. Psicothema 18:100-104
34. Penn RB, Pronin AN, Benovic JL (2000) Regulation of G protein coupled receptor kinases. Trends Cardiovasc Med 10:81-89
35. Perkins KA, Grobe JE (1992) Increased desire to smoke during acute stress. Br J Addict 87(7):1037-1040
36. Pluzarev O, Pandey SC (2004) Modulation of CREB expression and phosphorylation in the rat nucleus accumbens during nicotine exposure and withdrawal. J Neurosci Res 77(6):884-891
37. Portugal GS, Gould TJ (2009) Nicotine withdrawal disrupts new contextual learning. Pharmacol Biochem Behav 92:117-123
38. Poth K, Nutter TJ, Cuevas J, Parker MJ, Adams DJ, Luetje CW (1997) Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. J Neurosci 17:586-596
39. Rada P, Jensen K, Hoebel BG (2001) Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens. Psychopharmacology (Berl) 157(1):105-110
40. Rehni AK, Singh TG, Arora S (2012) SU-6656, a selective src kinase inhibitor, attenuates mecamylamine-precipitated nicotine withdrawal syndrome in mice. Nicotine Tob Res 14:407-414
41. Sofuoglu M, Herman AI, Mooney M, Waters AJ (2009) Varenicline attenuates some of the subjective and physiological effects of intravenous nicotine in humans. Psychopharmacology (Berl) 207:153-162
42. Stoker AK, Semenova S, Markou A (2008) Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice. Neuropharmacology 54(8):1223-1232
43. Teli T, Markovic D, Levine MA, Hillhouse EW, Grammatopoulos DK (2005) Regulation of corticotropin-releasing hormone receptor type 1 alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization. Mol Endocrinol 19(2):474-490
44. Vançelik S, Beyhun NE, Acemoǧlu H (2009) Interactions between exhaled CO, smoking status and nicotine dependency in a sample of Turkish adolescents. Turk J Pediatr 51:56-64