Response of liver to lipopolysaccharide treatment in male and female rats

Experimental and Toxicologic Pathology

Volumn 65, Issue 5, 2013, Pages 645-650

  Depboylu, Bilge ^a   Giriş, Murat ^a   Olgaç, Vakur ^b   Doĝru Abbasoĝlu, Semra ^a   Uysal, Müjdat ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Apoptosis; Gender; Lipopolysaccharide; Liver; Necrosis; Oxidative stress; Rat

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKADIENE; ALPHA TOCOPHEROL; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CASPASE 3; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIPID PEROXIDE; LIPOPOLYSACCHARIDE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELLULAR DISTRIBUTION; EXPERIMENTAL RAT; FEMALE; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER CELL; LIVER NECROSIS; LIVER TOXICITY; LYMPHOCYTIC INFILTRATION; MALE; MOLECULAR PATHOLOGY; MORTALITY; NONHUMAN; OXIDATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SEX DIFFERENCE; TOXICITY TESTING; TOXICOLOGICAL PARAMETERS;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; FEMALE; IN SITU NICK-END LABELING; LIPID PEROXIDES; LIPOPOLYSACCHARIDES; LIVER; MALE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; SEX CHARACTERISTICS;

RATTUS; RATTUS NORVEGICUS;

EID: 84878357654     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2012.07.004     Document Type: Article

References (35)

1. Adrie C., Azoulay E., Francais A., Clećh C., Darques L., Scwebel C., et al. Influence of gender on the outcome of severe sepsis: a reappraisal. Chest 2007, 132:1786-1793.
2. Aoshiba K., Onizawa S., Tsuji T., Nagai A. Therapeutic effects of erythropoietin in murine models of endotoxin shock. Critical Care Medicine 2009, 37:889-898.
3. Balkan J., Pari{dotless}ldar F.H., Doĝru-Abbasoĝlu S., Aykaç-Toker G., Uysal M. The effect of taurine or betaine pretreatment on hepatotoxicity and prooxidant status induced by polysaccharide treatment in the liver of rats. European Journal of Gastroenterology and Hepatology 2005, 17:917-921.
4. Beutler E., Duron O., Kelly B.M. Improved method for the determination of blood glutathione. Journal of Laboratory and Clinical Medicine 1963, 61:882-888.
5. Borras C., Sastre J., Garcia-Sala D., Lloret A., Pallardo F.V., Vina J. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radical Biology and Medicine 2003, 34:546-552.
6. Buege J.A., Aust J.D. Microsomal lipid peroxidation. Methods in Enzymology 1978, 52:302-310.
7. Carrillo-Vico A., Lardone P.J., Naji L., Fernandez-Santos J.M., Martin-Lacave I., Guerrero J.M., et al. Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects. Journal of Pineal Research 2005, 39:400-408.
8. Catala-Niell A., Estrany M.E., Proenza A.M., Gianotti M., Llado I. Skeletal muscle and liver oxidative metabolism in response to a voluntary isocaloric intake of a high fat diet in male and female rats. Cellular Physiology and Biochemistry 2008, 22:327-336.
9. Desai D.I., Vitamin E. analysis methods for animal tissues. Methods in Enzymology 1984, 105:138-147.
10. Erikoĝlu M., şahin M., özer ş., Avunduk M.C. Effects of gender on the severity of sepsis. Surgery Today 2005, 35:467-472.
11. Giriş M., Erbil Y., Depboylu B., Mete ö., Türkoĝlu ü., Doĝru-Abbasoĝlu S., et al. Heme oxygenase-1 prevents hyperthyroidism induced hepatic damage via an antioxidant and antiapoptotic pathway. Journal of Surgical Research 2010, 164:266-275.
12. Giriwono P.E., Shirakawa H., Hokazono H., Goto T., Komai M. Fermented barley extract supplementation maintained antioxidative defence suppressing lipopolysaccharide-induced inflammatory liver injury in rats. Bioscience, Biotechnology, and Biochemistry 2011, 75:1971-1976.
13. Habig W.H., Jacoby W.B. Assays for differentiation of glutathione s-transferases. Methods in Enzymology 1981, 77:398-405.
14. Inaba K., Suzuki S., Ihara H., Sakaguchi T., Baba S., Urano T., et al. Sexual dimorphism in endotoxin susceptibility after partial hepatectomy in rats. Journal of Hepatology 2005, 42:719-727.
15. Jeschke M.G., Rensing H., Klein D., Schubert T., Mautes A.E., Bolder U., et al. Insulin prevents liver damage and preserves liver function in lipopolysaccharide-induced endotoxemic rats. Journal of Hepatology 2005, 42:870-879.
16. Kao E.S., Hsu J.D., Wang C.J., Yang S.H., Cheng S.Y., Lee H.J. Polyphenols extracted from Hibiscus sabdariffa L. inhibited lipopolysaccharide-induced inflammation by improving antioxidative conditions and regulating cyclooxygenase-2 expression. Bioscience, Biotechnology, and Biochemistry 2009, 73:385-390.
17. Katalinic V., Modun D., Music I., Boban M. Gender differences in antioxidant capacity of rat tissues determined by 2,2'-azinobis(3-ethylbenzothiazoline 6-sulfonate; ABTS) and ferric reducing antioxidant power (FRAP) assays. Comparative Biochemistry and Physiology C: Comparative Pharmacology 2005, 140:47-52.
18. Kim I.D., Ha B.J. The effect of paeoniflorin on LPS-induced liver inflammatory reactions. Archives of Pharmacal Research 2010, 33:959-966.
19. Knöferl M.W., Angele M.K., Diyotato M.D., Schwacha M.G., Ayala A., Cioffi W.G., et al. Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Annals of Surgery 2002, 235:105-112.
20. Kuwabara T., Imajoh-Ohmi S. LPS-induced apoptosis is dependent upon mitochondrial dysfunction. Apoptosis 2004, 9:467-474.
21. Lawrence R.A., Burk R.F. Glutathione peroxidase activity in selenium deficient rat liver. Biochemical and Biophysical Research Communications 1976, 71:952-958.
22. Mylorie A.A., Collins H., Umbles C., Kyle J. Erythrocyte superoxide dismutase activity and other parameters of copper status in rats ingesting lead acetate. Toxicology and Applied Pharmacology 1986, 82:512-520.
23. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 1979, 95:351-358.
24. Omaye S.T., Turnbull J.D., Sauberlich H.E. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Methods in Enzymology 1979, 62:3-8.
25. Orrenius S., Gogvadze V., Zhivotovsky B. Mitochondrial oxidative stress: implications for cell death. Annual Review of Pharmacology and Toxicology 2007, 47:143-183.
26. Roberts R.A., Ganey P.E., Ju C., Kamendulis L.M., Rusyn I., Klaunig J.E. Role of the Kuffer cell mediating hepatic toxicity and carcinogenesis. Toxicological Sciences 2007, 96:2-15.
27. Sanz A., Hiona A., Kujoth G.C., Seo A.Y., Hofer T., Kouwenhoven E., et al. Evaluation of sex differences on mitochondrial bioenergetics and apoptosis in mice. Experimental Gerontology 2007, 42:173-182.
28. Schafer T., Scheuer C., Roemer K., Menger M.D., Vollmar B. Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death. FASEB Journal 2003, 17:660-667.
29. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., et al. Measurement of protein using bicinchoninic acid. Analytical Biochemistry 1985, 150:76-85.
30. Spitzer J.A. Gender differences in some host defence mechanisms. Lupus 1999, 8:380-383.
31. Victor V.M., Rocha M., DeLa Fuente M. Immune cells: free radicals and antioxidants in sepsis. International Immunopharmacology 2004, 4:327-347.
32. Wesche-Soldato D.E., Swan R.Z., Chung C.S., Ayala A. The apoptotic pathway as a therapeutic target in sepsis. Current Drug Targets 2007, 8:493-500.
33. Yokoyama Y., Nimura Y., Nagino M., Bland K.I., Chaudry I.H. Current understanding of gender dimorphism in hepatic pathophysiology. Journal of Surgical Research 2005, 128:147-156.
34. Zapelini P.H., Rezin G.T., Cardoso M.R., Ritter C., Klamt F., Moreira J.C.F., et al. Antioxidant treatment reverses mitochondrial dysfunction in a sepsis animal model. Mitochondrion 2008, 8:211-218.
35. Zhong J., Deaciuc I.V., Burikhanov R., De Villiers W.J.S. Lipopolysaccharide-induced liver apoptosis is increased in interleukin-10 knockout mice. Biochimica et Biophysica Acta 2006, 1762:468-477.