메뉴 건너뛰기




Volumn 405, Issue 15, 2013, Pages 5341-5351

Identification and functional characterization of a novel α-conotoxin (EIIA) from Conus ermineus

Author keywords

Conotoxin; Binding experiments; Conus venom; De novo sequencing; Mass spectrometry; Nicotinic acetylcholine receptors

Indexed keywords

CONOTOXINS; CONUS VENOMS; DE NOVO SEQUENCING; FUNCTIONAL CHARACTERIZATION; LIGAND-GATED ION CHANNELS; NICOTINIC ACETYLCHOLINE RECEPTORS; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHRS); POST-TRANSLATIONAL MODIFICATIONS;

EID: 84878310310     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-6926-x     Document Type: Article
Times cited : (21)

References (36)
  • 1
    • 0035251761 scopus 로고    scopus 로고
    • Overview of nicotinic receptors and their roles in the central nervous system
    • 10.1016/S0006-3223(00)01011-8 1:CAS:528:DC%2BD3MXhsFSjtLY%3D
    • Dani JA (2001) Overview of nicotinic receptors and their roles in the central nervous system. Biol Psychiat 49(3):166-174
    • (2001) Biol Psychiat , vol.49 , Issue.3 , pp. 166-174
    • Dani, J.A.1
  • 2
    • 0347989461 scopus 로고    scopus 로고
    • Conus venoms: A rich source of novel ion channel-targeted peptides
    • 10.1152/physrev.00020.2003 1:CAS:528:DC%2BD2cXotl2rtA%3D%3D
    • Terlau H, Olivera BM (2004) Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol Rev 84(1):41-68
    • (2004) Physiol Rev , vol.84 , Issue.1 , pp. 41-68
    • Terlau, H.1    Olivera, B.M.2
  • 3
    • 77952240443 scopus 로고    scopus 로고
    • Conopeptide characterization and classifications: An analysis using ConoServer
    • 10.1016/j.toxicon.2010.03.002 1:CAS:528:DC%2BC3cXltFGgtb4%3D
    • Kaas Q, Westermann J, Craik D (2010) Conopeptide characterization and classifications: an analysis using ConoServer. Toxicon 55:1491-1509
    • (2010) Toxicon , vol.55 , pp. 1491-1509
    • Kaas, Q.1    Westermann, J.2    Craik, D.3
  • 4
    • 33751049816 scopus 로고    scopus 로고
    • Conotoxins down under
    • 10.1016/j.toxicon.2006.07.022 1:CAS:528:DC%2BD28Xht1WnsLbL
    • Norton RS, Olivera BM (2006) Conotoxins down under. Toxicon 48(7):780-798
    • (2006) Toxicon , vol.48 , Issue.7 , pp. 780-798
    • Norton, R.S.1    Olivera, B.M.2
  • 8
    • 34547637063 scopus 로고    scopus 로고
    • Alpha c-conotoxin prxa: A new family of nicotinic acetylcholine receptor antagonists
    • 10.1021/bi700582m 1:CAS:528:DC%2BD2sXnt1Snsrc%3D
    • Jimenez EC, Olivera BM, Teichert RW (2007) Alpha c-conotoxin prxa: a new family of nicotinic acetylcholine receptor antagonists. Biochemistry 46(30):8717-8724
    • (2007) Biochemistry , vol.46 , Issue.30 , pp. 8717-8724
    • Jimenez, E.C.1    Olivera, B.M.2    Teichert, R.W.3
  • 9
    • 19644387101 scopus 로고    scopus 로고
    • Alpha S-conotoxin RVIIIA: A structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors
    • 10.1021/bi047274+
    • Teichertt RW, Jimenez EC, Olivera BM (2005) Alpha S-conotoxin RVIIIA: a structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors. Biochemistry 44(21):7897-7902
    • (2005) Biochemistry , vol.44 , Issue.21 , pp. 7897-7902
    • Teichertt, R.W.1    Jimenez, E.C.2    Olivera, B.M.3
  • 10
    • 33747666931 scopus 로고    scopus 로고
    • Identification of a novel class of nicotinic receptor antagonists: Dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum
    • 10.1074/jbc.M603703200 1:CAS:528:DC%2BD28Xot1eqtLY%3D
    • Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ (2006) Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. J Biol Chem 281(34):24745-24755
    • (2006) J Biol Chem , vol.281 , Issue.34 , pp. 24745-24755
    • Loughnan, M.1    Nicke, A.2    Jones, A.3    Schroeder, C.I.4    Nevin, S.T.5    Adams, D.J.6    Alewood, P.F.7    Lewis, R.J.8
  • 11
    • 0033198875 scopus 로고    scopus 로고
    • Post-translationally modified neuropeptides from Conus venoms
    • 10.1046/j.1432-1327.1999.00624.x 1:CAS:528:DyaK1MXlvFWktbc%3D
    • Craig AG, Bandyopadhyay P, Olivera BM (1999) Post-translationally modified neuropeptides from Conus venoms. Eur J Biochem 264(2):271-275
    • (1999) Eur J Biochem , vol.264 , Issue.2 , pp. 271-275
    • Craig, A.G.1    Bandyopadhyay, P.2    Olivera, B.M.3
  • 12
    • 2342593352 scopus 로고    scopus 로고
    • De novo sequencing, peptide composition analysis, and composition-based sequencing: A new strategy employing accurate mass determination by Fourier transform ion cyclotron resonance mass spectrometry
    • 10.1016/j.jasms.2004.01.007 1:CAS:528:DC%2BD2cXjs1art70%3D
    • Spengler B (2004) De novo sequencing, peptide composition analysis, and composition-based sequencing: a new strategy employing accurate mass determination by Fourier transform ion cyclotron resonance mass spectrometry. J Am Soc Mass Spectrom 15(5):703-714
    • (2004) J Am Soc Mass Spectrom , vol.15 , Issue.5 , pp. 703-714
    • Spengler, B.1
  • 14
    • 0033567060 scopus 로고    scopus 로고
    • A comparison between the sulfhydryl reductants tris(2-carboxyethyl) phosphine and dithiothreitol for use in protein biochemistry
    • 10.1006/abio.1999.4203 1:CAS:528:DyaK1MXlt1Wktbg%3D
    • Getz EB, Xiao M, Chakrabarty T, Cooke R, Selvin PR (1999) A comparison between the sulfhydryl reductants tris(2-carboxyethyl)phosphine and dithiothreitol for use in protein biochemistry. Anal Biochem 273(1):73-80
    • (1999) Anal Biochem , vol.273 , Issue.1 , pp. 73-80
    • Getz, E.B.1    Xiao, M.2    Chakrabarty, T.3    Cooke, R.4    Selvin, P.R.5
  • 15
    • 0027772476 scopus 로고
    • Chimeric nicotinic serotonergic receptor combines distinct ligand-binding and channel specificities
    • 10.1038/366479a0 1:CAS:528:DyaK2cXisVWhsA%3D%3D
    • Eisele JL, Bertrand S, Galzi JL, Devillersthiery A, Changeux JP, Bertrand D (1993) Chimeric nicotinic serotonergic receptor combines distinct ligand-binding and channel specificities. Nature 366(6454):479-483
    • (1993) Nature , vol.366 , Issue.6454 , pp. 479-483
    • Eisele, J.L.1    Bertrand, S.2    Galzi, J.L.3    Devillersthiery, A.4    Changeux, J.P.5    Bertrand, D.6
  • 16
    • 0030766456 scopus 로고    scopus 로고
    • Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha 7 nicotinic receptor
    • 10.1074/jbc.272.39.24279 1:CAS:528:DyaK2sXmsFamsrk%3D
    • Servent D, WincklerDietrich V, Hu HY, Kessler P, Drevet P, Bertrand D, Menez A (1997) Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha 7 nicotinic receptor. J Biol Chem 272(39):24279-24286
    • (1997) J Biol Chem , vol.272 , Issue.39 , pp. 24279-24286
    • Servent, D.1    Wincklerdietrich, V.2    Hu, H.Y.3    Kessler, P.4    Drevet, P.5    Bertrand, D.6    Menez, A.7
  • 17
    • 78751646313 scopus 로고    scopus 로고
    • Intraspecies variability and conopeptide profiling of the injected venom of Conus ermineus
    • 10.1016/j.peptides.2010.11.014 1:CAS:528:DC%2BC3MXpslyksw%3D%3D
    • Rivera-Ortiz JA, Cano H, Mari F (2011) Intraspecies variability and conopeptide profiling of the injected venom of Conus ermineus. Peptides 32(2):306-316
    • (2011) Peptides , vol.32 , Issue.2 , pp. 306-316
    • Rivera-Ortiz, J.A.1    Cano, H.2    Mari, F.3
  • 20
    • 0033714035 scopus 로고    scopus 로고
    • Alpha-conotoxins
    • 10.1016/S1357-2725(00)00051-0 1:CAS:528:DC%2BD3cXot12murY%3D
    • Arias HR, Blanton MP (2000) Alpha-conotoxins. Int J Biochem Cell B 32(10):1017-1028
    • (2000) Int J Biochem Cell B , vol.32 , Issue.10 , pp. 1017-1028
    • Arias, H.R.1    Blanton, M.P.2
  • 22
    • 27144510069 scopus 로고    scopus 로고
    • Characterization of toxins within crude venoms by combined use of Fourier transform mass spectrometry and cloning
    • 10.1021/ac050575k 1:CAS:528:DC%2BD2MXpvFOksrc%3D
    • Quinton L, Le Caer JP, Phan G, Ligny-Lemaire C, Bourdais-Jomaron J, Ducancel F, Chamot-Rooke J (2005) Characterization of toxins within crude venoms by combined use of Fourier transform mass spectrometry and cloning. Anal Chem 77(20):6630-6639
    • (2005) Anal Chem , vol.77 , Issue.20 , pp. 6630-6639
    • Quinton, L.1    Le Caer, J.P.2    Phan, G.3    Ligny-Lemaire, C.4    Bourdais-Jomaron, J.5    Ducancel, F.6    Chamot-Rooke, J.7
  • 23
    • 33646470012 scopus 로고    scopus 로고
    • Fourier transform mass spectrometry: A powerful tool for toxin analysis
    • 10.1016/j.toxicon.2006.01.023 1:CAS:528:DC%2BD28XktVWnur8%3D
    • Quinton L, Le Caer JP, Vinh J, Gilles N, Chamot-Rooke J (2006) Fourier transform mass spectrometry: a powerful tool for toxin analysis. Toxicon 47(6):715-726
    • (2006) Toxicon , vol.47 , Issue.6 , pp. 715-726
    • Quinton, L.1    Le Caer, J.P.2    Vinh, J.3    Gilles, N.4    Chamot-Rooke, J.5
  • 24
    • 0038034116 scopus 로고    scopus 로고
    • Cleavage N-terminal to proline: Analysis of a database of peptide tandem mass spectra
    • 10.1021/ac026359i 1:CAS:528:DC%2BD3sXitlGlsLo%3D
    • Breci LA, Tabb DL, Yates JR, Wysocki VH (2003) Cleavage N-terminal to proline: analysis of a database of peptide tandem mass spectra. Anal Chem 75(9):1963-1971
    • (2003) Anal Chem , vol.75 , Issue.9 , pp. 1963-1971
    • Breci, L.A.1    Tabb, D.L.2    Yates, J.R.3    Wysocki, V.H.4
  • 25
    • 0035983630 scopus 로고    scopus 로고
    • New example of proline-induced fragmentation in electrospray ionization mass spectrometry of peptides
    • 10.1002/rcm.741 1:CAS:528:DC%2BD38XlvFKitr8%3D
    • Maux D, Enjalbal C, Martinez J, Aubagnac JL (2002) New example of proline-induced fragmentation in electrospray ionization mass spectrometry of peptides. Rapid Commun Mass Spectrom 16(15):1470-1475
    • (2002) Rapid Commun Mass Spectrom , vol.16 , Issue.15 , pp. 1470-1475
    • Maux, D.1    Enjalbal, C.2    Martinez, J.3    Aubagnac, J.L.4
  • 26
    • 34249072034 scopus 로고    scopus 로고
    • A novel alpha conotoxin (alpha-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors
    • 10.1016/j.toxicon.2007.02.007 1:CAS:528:DC%2BD2sXlslWjsbo%3D
    • Lopez-Vera E, Jacobsen RB, Ellison M, Olivera BM, Teichert RW (2007) A novel alpha conotoxin (alpha-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors. Toxicon 49(8):1193-1199
    • (2007) Toxicon , vol.49 , Issue.8 , pp. 1193-1199
    • Lopez-Vera, E.1    Jacobsen, R.B.2    Ellison, M.3    Olivera, B.M.4    Teichert, R.W.5
  • 27
    • 12844251304 scopus 로고    scopus 로고
    • Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors
    • 1:CAS:528:DC%2BD2cXhtFGnsr%2FK
    • Azam L, Dowell C, Watkins M, Stitzel JA, Olivera BM, McIntosh JM (2005) Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors. J Biol Chem 280(1):80-87
    • (2005) J Biol Chem , vol.280 , Issue.1 , pp. 80-87
    • Azam, L.1    Dowell, C.2    Watkins, M.3    Stitzel, J.A.4    Olivera, B.M.5    McIntosh, J.M.6
  • 28
    • 70349604421 scopus 로고    scopus 로고
    • Characterization of a novel alpha 4/4-conotoxin, Qc1.2, from vermivorous Conus quercinus
    • 10.1093/abbs/gmp077 1:CAS:528:DC%2BD1MXhtFygsrnE
    • Peng C, Chen WH, Han YH, Sanders T, Chew G, Liu J, Hawrot E, Chi CW, Wang CG (2009) Characterization of a novel alpha 4/4-conotoxin, Qc1.2, from vermivorous Conus quercinus. Acta Bioch Bioph Sin 41(10):858-864
    • (2009) Acta Bioch Bioph Sin , vol.41 , Issue.10 , pp. 858-864
    • Peng, C.1    Chen, W.H.2    Han, Y.H.3    Sanders, T.4    Chew, G.5    Liu, J.6    Hawrot, E.7    Chi, C.W.8    Wang, C.G.9
  • 29
    • 2342444944 scopus 로고    scopus 로고
    • The α-superfamily of conotoxins - Structural and functional divergence
    • 10.1074/jbc.M309654200 1:CAS:528:DC%2BD2cXjt1GntLk%3D
    • Santos AD, McIntosh JM, Hillyard DR, Cruz LJ, Olivera BM (2004) The α-superfamily of conotoxins - structural and functional divergence. J Biol Chem 279(17):17596-17606
    • (2004) J Biol Chem , vol.279 , Issue.17 , pp. 17596-17606
    • Santos, A.D.1    McIntosh, J.M.2    Hillyard, D.R.3    Cruz, L.J.4    Olivera, B.M.5
  • 30
    • 0028984297 scopus 로고
    • Alpha-conotoxins selectively inhibit one of the 2 acetylcholine binding-sites of nicotinic receptors
    • 1:CAS:528:DyaK2MXntFakurc%3D
    • Groebe DR, Dumm JM, Levitan ES, Abramson SN (1995) Alpha-conotoxins selectively inhibit one of the 2 acetylcholine binding-sites of nicotinic receptors. Mol Pharmacol 48(1):105-111
    • (1995) Mol Pharmacol , vol.48 , Issue.1 , pp. 105-111
    • Groebe, D.R.1    Dumm, J.M.2    Levitan, E.S.3    Abramson, S.N.4
  • 31
    • 0030982176 scopus 로고    scopus 로고
    • Determinants involved in the affinity of alpha-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors
    • 10.1021/bi970195w 1:CAS:528:DyaK2sXivF2nt7k%3D
    • Groebe DR, Gray WR, Abramson SN (1997) Determinants involved in the affinity of alpha-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors. Biochemistry 36(21):6469-6474
    • (1997) Biochemistry , vol.36 , Issue.21 , pp. 6469-6474
    • Groebe, D.R.1    Gray, W.R.2    Abramson, S.N.3
  • 32
    • 0032857339 scopus 로고    scopus 로고
    • Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors
    • 10.1021/bi9907476 1:CAS:528:DyaK1MXlslOnsrc%3D
    • Jacobsen RB, DelaCruz RG, Grose JH, McIntosh JM, Yoshikami D, Olivera BM (1999) Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors. Biochemistry 38(40):13310-13315
    • (1999) Biochemistry , vol.38 , Issue.40 , pp. 13310-13315
    • Jacobsen, R.B.1    Delacruz, R.G.2    Grose, J.H.3    McIntosh, J.M.4    Yoshikami, D.5    Olivera, B.M.6
  • 33
    • 0028170805 scopus 로고
    • The alpha-conotoxins GI and MI distinguish between the nicotinic acetylcholine-receptor agonist sites while SI does not
    • 10.1021/bi00251a014 1:CAS:528:DyaK2cXmvFegt7k%3D
    • Hann RM, Pagan OR, Eterovic VA (1994) The alpha-conotoxins GI and MI distinguish between the nicotinic acetylcholine-receptor agonist sites while SI does not. Biochemistry 33(47):14058-14063
    • (1994) Biochemistry , vol.33 , Issue.47 , pp. 14058-14063
    • Hann, R.M.1    Pagan, O.R.2    Eterovic, V.A.3
  • 34
    • 0028973580 scopus 로고
    • Alpha-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity
    • 10.1021/bi00044a030 1:CAS:528:DyaK2MXoslGhsrg%3D
    • Martinez JS, Olivera BM, Gray WR, Craig AG, Groebe DR, Abramson SN, Mc Intosh JM (1995) alpha-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity. Biochemistry 34(44):14519-14526
    • (1995) Biochemistry , vol.34 , Issue.44 , pp. 14519-14526
    • Martinez, J.S.1    Olivera, B.M.2    Gray, W.R.3    Craig, A.G.4    Groebe, D.R.5    Abramson, S.N.6    Mc Intosh, J.M.7
  • 36
    • 0030791182 scopus 로고    scopus 로고
    • The 9-arginine residue of alpha-conotoxin GI is responsible for its selective high affinity for the alphagamma agonist site on the electric organ acetylcholine receptor
    • 10.1021/bi970807c 1:CAS:528:DyaK2sXkt1GgsLk%3D
    • Hann RM, Pagán OR, Gregory LM, Jácome T, Eterović VA (1997) The 9-arginine residue of alpha-conotoxin GI is responsible for its selective high affinity for the alphagamma agonist site on the electric organ acetylcholine receptor. Biochemistry 36(29):9051-9056
    • (1997) Biochemistry , vol.36 , Issue.29 , pp. 9051-9056
    • Hann, R.M.1    Pagán, O.R.2    Gregory, L.M.3    Jácome, T.4    Eterović, V.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.