Repair of an articular cartilage defect using adipose-derived stem cells loaded on a polyelectrolyte complex scaffold based on poly(l-glutamic acid) and chitosan

Acta Biomaterialia

Volumn 9, Issue 7, 2013, Pages 7276-7288

  Zhang, Kunxi ^a   Zhang, Yun ^b   Yan, Shifeng ^a   Gong, Lunli ^b   Wang, Jia ^a   Chen, Xuesi ^c   Cui, Lei ^b   Yin, Jingbo ^a  

^a SHANGHAI UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

Author keywords

Adipose derived stem cells; Cartilage tissue engineering; Chondrogenic differentiation; Poly(l glutamic acid); Polyelectrolyte scaffold

Indexed keywords

AMINO ACIDS; BIOCOMPATIBILITY; BIODEGRADATION; BONE; CELL ENGINEERING; CHITOSAN; DEFECTS; POLYELECTROLYTES; REPAIR; SCAFFOLDS (BIOLOGY); STEM CELLS;

ADIPOSE DERIVED STEM CELLS; ARTICULAR CARTILAGE DEFECTS; CARTILAGE TISSUE ENGINEERING; CHITOSAN SCAFFOLD; CHONDROGENIC DIFFERENTIATION; ENGINEERED CARTILAGE; POLY(L-GLUTAMIC ACID); POLY(LGLUTAMIC ACID); POLY-L-GLUTAMIC ACIDS; POLYELECTROLYTE SCAFFOLD;

CARTILAGE;

CHITOSAN; POLYELECTROLYTE; POLYGLUTAMIC ACID; SOMATOMEDIN C; TOLONIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA1;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; BIOCOMPATIBILITY; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; DNA CONTENT; EXTRACELLULAR MATRIX; FREEZE DRYING; GENE EXPRESSION; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; PHASE SEPARATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; QUANTITATIVE ANALYSIS; RABBIT; TISSUE ENGINEERING; TISSUE REGENERATION; TRABECULAR BONE;

ORYCTOLAGUS CUNICULUS;

EID: 84878287655     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.03.025     Document Type: Article

References (36)

1. M. Ochi, Y. Uchio, M. Tobita, and M. Kuriwaka Current concepts in tissue engineering technique for repair of cartilage defect J Artif Organs 25 2001 172 179
2. H. Chiang, and C.C. Jiang Repair of articular cartilage defects: review and perspectives J Formos Med Assoc 108 2009 87 101
3. S.C. Neves Chitosan/poly(É-caprolactone) blend scaffolds for cartilage repair Biomaterials 32 2011 1068 1079
4. P.K. Valonen In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(É-caprolactone) scaffolds Biomaterials 31 2010 2193 2200
5. C. Ye, P. Hu, M.X. Ma, Y. Xiang, R.G. Liu, and X.W. Shang PHB/PHBHHx scaffolds and human adipose-derived stem cells for cartilage tissue engineering Biomaterials 30 2009 4401 4406
6. Y. Wang, Y.Z. Bian, Q. Wu, and G.Q. Chen Evaluation of three-dimensional scaffolds prepared from poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for growth of allogeneic chondrocytes for cartilage repair in rabbits Biomaterials 29 2008 2858 2868
7. L. Cao The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells Biomaterials 32 2011 3910 3920
8. D. Yan The impact of low levels of collagen IX and pyridinoline on the mechanical properties of in vitro engineered cartilage Biomaterials 30 2009 814 821
9. H.C. Chen, Y.H. Chang, C.K. Chuang, C.Y. Lin, L.Y. Sung, and Y.H. Wang The repair of osteochondral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture Biomaterials 30 2009 674 681
10. W. Wang The restoration of full-thickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs Biomaterials 31 2010 8964 8973
11. W. Wang, B. Li, Y.L. Li, Y.Z. Jiang, H.W. Ouyang, and C.Y. Gao In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes Biomaterials 31 2010 5953 5965
12. W.D. Dai, N. Kawazoe, X.T. Lin, J. Dong, and G.P. Chen The influence of structural design of PLGA/collagen hybrid scaffolds in cartilage tissue engineering Biomaterials 31 2010 2141 2152
13. R. Thull Surface functionalization of materials to initiate auto-biocompatibilization in vivo Materialwiss Werkst 32 2001 949 952
14. B. Cao, J.B. Yin, S.F. Yan, L. Cui, X.S. Chen, and Y.T. Xie Porous scaffolds based on cross-linking of poly(l-glutamic acid) Macromol Biosci 11 2011 427 434
15. M.X. Deng, R. Wang, G.Z. Rong, J.R. Sun, X.F. Zhang, and X.S. Chen Synthesis of poly(g-benzyl-l-glutamic acid)-b-poly(ethylene oxide)-b- poly(É-caprolactone) triblock copolymer Biomaterials 25 2004 3553 3558
16. Wang FY. Bionic design and initial preparation of tissue engineered osteochondral composites. Ph.D. Thesis. Third Military Medical University; 2008.
17. I.K. Shim, W.H. Suh, S.Y. Lee, S.H. Lee, S.J. Heo, and M.C. Lee Chitosan nano-/microfibrous double-layered membrane with rolled-up three-dimensional structures for chondrocyte cultivation J Biomed Mater Res 90A 2009 595 602
18. B. Cao, S.F. Yan, K.X. Zhang, Z.J. Song, X.S. Chen, and L. Cui Layer-by-layer assembled multilayer films of methoxy poly(ethylene glycol)-b-poly(α,l-glutamic acid) and chitosan with reduced cell adhesion Macromol Biosci 11 2011 1211 1217
19. K. Luo, J. Yin, Z. Song, L. Cui, B. Cao, and X. Chen Biodegradable interpolyelectrolyte complexes based on methoxy poly(ethylene glycol)-b-poly(α,l-glutamic acid) and chitosan Biomacromolecules 9 2008 2653 2661
20. P. Dubruel, L. Dekie, and E. Schacht Poly-l-glutamic acid derivatives as multifunctional vectors for gene delivery. Part A. Synthesis and physicochemical evaluation Biomacromolecules 4 2003 1168 1176
21. Z.J. Song Layer-by-layer buildup of poly(l-glutamic acid)/chitosan film for biologically active coating Macromol Biosci 9 2009 268 278
22. L. Cui Repair of articular cartilage defect in non-weight bearing areas using adipose derived stem cells loaded polyglycolic acid mesh Biomaterials 30 2009 2683 2693
23. L. Cui Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model Biomaterials 28 2007 5477 5486
24. S.D. Cook, L.P. Patron, S.L. Salkeld, and D.C. Rueger Repair of articular cartilage defects with osteogenic protein-1 (BMP-7) in dogs J Bone Joint Surg Am 85 2003 116 123
25. S. Wakitani Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage J Bone Joint Surg Am 76 1994 579 592
26. A. Domard, and M. Rinaudo Polyelectrolyte complexes. Interaction of poly(l-lysine)-poly(l-glutamic acid) in dilute aqueous solution Macromolecules 13 1980 898 904
27. A.D. Martino, M. Sittinger, and M.V. Risbud Chitosan: a versatile biopolymer for orthopaedic tissue-engineering Biomaterials 26 2005 5983 5990
28. J.K. Francis Suh, and H.W.T. Matthew Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review Biomaterials 21 2000 2589 2598
29. D.J. Griffon, M. Reza Sedighi, D.V. Schaeffer, J.A. Eurell, and A.L. Johnson Chitosan scaffolds: interconnective pore size and cartilage engineering Acta Biomater 2 2006 313 320
30. D.L. Nettles, S.H. Elder, and J.A. Gilbert Potential use of chitosan as a cell scaffold material for cartilage tissue engineering Tissue eng 8 2002 1009 1016
31. K.A. Corin, and L.J. Gibson Cell contraction forced in scaffolds with varying pore size and cell density Biomaterials 31 2010 4835 4845
32. J.M. Sobral, S.G. Caridade, R.A. Sousa, J.F. Mano, and R.L. Reis Three-dimensional plotted scaffolds with controlled pore size gradients: effect of scaffold geometry on mechanical performance and cell seeding efficiency Acta Biomater 7 2010 1009 1018
33. H.R. Dickinson, A. Hiltner, D.F. Gibbons, and J.M. Anderson Biodegradation of a poly(a-amino acid) hydrogel. I. In vivo J Biomed Mater Res 15 1981 577 589
34. H.R. Dichinson, and A. Hiltner Biodegradation of a poly-(a-amino acid) hydrogel. II. In vitro J Biomed Mater Res 15 1981 591 603
35. O. Franke, K. Durst, V. Maier, and M. Goken Mechanical properties of hyaline and repair cartilage studied by nanoindentation Acta Biomater 3 2007 873 881
36. B.S. Kim, and D.J. Mooney Development of biocompatible synthetic extracellular matrices for tissue engineering Trends Biotechnol 16 1998 224 230