Acute phase homocysteine related to severity and outcome of atherothrombotic stroke

European Journal of Internal Medicine

Volumn 24, Issue 4, 2013, Pages 362-367

  Wu, Xu Qing ^a   Ding, Jing ^a   Ge, An Yan ^a   Liu, Fei Feng ^a   Wang, Xin ^a   Fan, Wei ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Atherothrombosis; Homocysteine; Modified TOAST classification; Prognosis

Indexed keywords

FOLIC ACID; HOMOCYSTEINE; LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ARTICLE; BARTHEL INDEX; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; PROSPECTIVE STUDY; RANKIN SCALE; THROMBOSIS; VITAMIN SUPPLEMENTATION;

ADULT; AGED; AGED, 80 AND OVER; ATHEROSCLEROSIS; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HOMOCYSTEINE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; PROSPECTIVE STUDIES; RECURRENCE; SEVERITY OF ILLNESS INDEX; STROKE; THROMBOSIS;

EID: 84878281417     PISSN: 09536205     EISSN: 18790828     Source Type: Journal    
DOI: 10.1016/j.ejim.2013.01.015     Document Type: Article

References (33)

1. J.D. Spence Homocysteine-lowering therapy: a role in stroke prevention? Lancet Neurol 6 2007 830 838
2. S.J. Kittner, W.H. Giles, R.F. Macko, J.R. Hebel, M.A. Wozniak, and R.J. Wityk Homocyst(e)ine and risk of cerebral infarction in a biracial population: the stroke prevention in young women study Stroke 30 1999 1554 1560
3. A.G. Bostom, I.H. Rosenberg, H. Silbershatz, P.F. Jacques, J. Selhub, and R.B. D'Agostino Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the framingham study Ann Intern Med 131 1999 352 355
4. M.L. Bots, L.J. Launer, J. Lindemans, A.W. Hoes, A. Hofman, and J.C. Witteman Homocysteine and short-term risk of myocardial infarction and stroke in the elderly: the Rotterdam study Arch Intern Med 159 1999 38 44
5. Homocysteine Studies Collaboration Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis JAMA 288 2002 2015 2022
6. M. Lee, K.S. Hong, S.C. Chang, and J.L. Saver Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis Stroke 41 2010 1205 1212
7. F. Perini, E. Galloni, I. Bolgan, G. Bader, R. Ruffini, and E. Arzenton Elevated plasma homocysteine in acute stroke was not associated with severity and outcome: stronger association with small artery disease Neurol Sci 26 2005 310 318
8. E. Haapaniemi, J. Helenius, L. Soinne, M. Syrjala, M. Kaste, and T. Tatlisumak Serial measurements of plasma homocysteine levels in early and late phases of ischemic stroke Eur J Neurol 14 2007 12 17
9. I.U. Song, J.S. Kim, S.Y. Ryu, S.B. Lee, S.J. Lee, and D.S. Jeong Are plasma homocysteine levels related to neurological severity and functional outcome after ischemic stroke in the korean population? J Neurol Sci 278 2009 60 63
10. J. Pniewski, M. Chodakowska-Zebrowska, R. Wozniak, K. Stepien, and A. Stafiej Plasma homocysteine level and the course of ischemic stroke Acta Neurobiol Exp (Wars) 63 2003 127 130
11. J. Kalita, G. Kumar, V. Bansal, and U.K. Misra Relationship of homocysteine with other risk factors and outcome of ischemic stroke Clin Neurol Neurosurg 111 2009 364 367
12. N.U. Okubadejo, O.O. Oladipo, A.A. Adeyomoye, G.O. Awosanya, and M.A. Danesi Exploratory study of plasma total homocysteine and its relationship to short-term outcome in acute ischaemic stroke in nigerians BMC Neurol 8 2008 26
13. E.H. Mizrahi, Y. Fleissig, M. Arad, and A. Adunsky Plasma homocysteine level and functional outcome of patients with ischemic stroke Arch Phys Med Rehabil 86 2005 60 63
14. H.J. Adams, B.H. Bendixen, L.J. Kappelle, J. Biller, B.B. Love, and D.L. Gordon Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. Toast. Trial of org 10172 in acute stroke treatment Stroke 24 1993 35 41
15. N.C. Tan, N. Venketasubramanian, S.M. Saw, and H.T. Tjia Hyperhomocyst(e)inemia and risk of ischemic stroke among young asian adults Stroke 33 2002 1956 1962
16. J.W. Eikelboom, G.J. Hankey, S.S. Anand, E. Lofthouse, N. Staples, and R.I. Baker Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke Stroke 31 2000 1069 1075
17. H. Shimizu, Y. Kiyohara, I. Kato, Y. Tanizaki, H. Ueno, and Y. Kimura Plasma homocyst(e)ine concentrations and the risk of subtypes of cerebral infarction. The Hisayama study Cerebrovasc Dis 13 2002 9 15
18. A. Lindgren, L. Brattstrom, B. Norrving, B. Hultberg, A. Andersson, and B.B. Johansson Plasma homocysteine in the acute and convalescent phases after stroke Stroke 26 1995 795 800
19. D.J. Meiklejohn, M.A. Vickers, R. Dijkhuisen, and M. Greaves Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke Stroke 32 2001 57 62
20. V.J. Howard, E.G. Sides, G.C. Newman, S.N. Cohen, G. Howard, and M.R. Malinow Changes in plasma homocyst(e)ine in the acute phase after stroke Stroke 33 2002 473 478
21. S. Hatano Experience from a multicentre stroke register: a preliminary report Bull World Health Organ 54 1976 541 553
22. S.W. Han, S.H. Kim, J.Y. Lee, C.K. Chu, J.H. Yang, and H.Y. Shin A new subtype classification of ischemic stroke based on treatment and etiologic mechanism Eur Neurol 57 2007 96 102
23. U. Khan, C. Crossley, L. Kalra, A. Rudd, C.D. Wolfe, and P. Collinson Homocysteine and its relationship to stroke subtypes in a uk black population: the south london ethnicity and stroke study Stroke 39 2008 2943 2949
24. A.K. Gehi, S. Ali, B. Na, and M.A. Whooley Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study Arch Intern Med 167 2007 1798 1803
25. H. Refsum, A.D. Smith, P.M. Ueland, E. Nexo, R. Clarke, and J. McPartlin Facts and recommendations about total homocysteine determinations: an expert opinion Clin Chem 50 2004 3 32
26. A. Coppola, G. Davi, V. De Stefano, F.P. Mancini, A.M. Cerbone, and G. Di Minno Homocysteine, coagulation, platelet function, and thrombosis Semin Thromb Hemost 26 2000 243 254
27. J.F. Toole, M.R. Malinow, L.E. Chambless, J.D. Spence, L.C. Pettigrew, and V.J. Howard Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the vitamin intervention for stroke prevention (visp) randomized controlled trial JAMA 291 2004 565 575
28. G. Saposnik, J.G. Ray, P. Sheridan, M. McQueen, and E. Lonn Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the hope 2 trial Stroke 40 2009 1365 1372
29. M. Lee, K.S. Hong, S.C. Chang, and J.L. Saver Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis Stroke 41 2010 1205 1212
30. G. Saposnik, J.G. Ray, P. Sheridan, M. McQueen, and E. Lonn Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the hope 2 trial Stroke 40 2009 1365 1372
31. B.N. Manolescu, E. Oprea, I.C. Farcasanu, M. Berteanu, and C. Cercasov Homocysteine and vitamin therapy in stroke prevention and treatment: a review Acta Biochim Pol 57 2010 467 477
32. H. Iso, Y. Moriyama, S. Sato, A. Kitamura, T. Tanigawa, and K. Yamagishi Serum total homocysteine concentrations and risk of stroke and its subtypes in japanese Circulation 109 2004 2766 2772
33. B. Kristensen, J. Malm, T.K. Nilsson, J. Hultdin, B. Carlberg, and G. Dahlen Hyperhomocysteinemia and hypofibrinolysis in young adults with ischemic stroke Stroke 30 1999 974 980