High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells

Cardiovascular Diabetology

Volumn 12, Issue 1, 2013, Pages

  Lu, Hao ^a   Yao, Kang ^a   Huang, Dong ^a   Sun, Aijun ^a   Zou, Yunzeng ^a   Qian, Juying ^a   Ge, Junbo ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Atherosclerosis; Dendritic cell; Immune response; Scavenger receptors; Type 2 diabetes

Indexed keywords

ACETYLCYSTEINE; CD36 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; DICHLORODIHYDROFLUORESCEIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; REACTIVE OXYGEN METABOLITE; SCAVENGER RECEPTOR; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; AUTACOID; CYTOKINE; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; OLR1 PROTEIN, HUMAN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN KINASE INHIBITOR; SCAVENGER RECEPTOR A;

ANTIGEN EXPRESSION; ARTICLE; CELL MATURATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; OSMOLARITY; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; ATHEROSCLEROSIS; CELL CULTURE; CELL DIFFERENTIATION; COMPLICATION; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HYPERGLYCEMIA; IMMUNOLOGY; METABOLISM;

ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD36; ANTIOXIDANTS; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; HUMANS; HYPERGLYCEMIA; INFLAMMATION MEDIATORS; LIPOPROTEINS, LDL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS A; SCAVENGER RECEPTORS, CLASS E;

EID: 84878252126     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-12-80     Document Type: Article

References (34)

1. Laakso M. Hyperglycemia and cardiovascular disease in type 2 diabetes. Diabetes 1999, 48:937-942. 10.2337/diabetes.48.5.937, 10331395.
2. UK prospective Diabetes Study (UKPDS) group Intensive blood-glucose control with sulphonyureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. Lancet 1998, 352:837-853. UK prospective Diabetes Study (UKPDS) group.
3. Coutinho M, Gerstein HC, Wang Y, Yusuf S. The relationship between glucose and incident cardiovascular events: a metaregression analysis of published data from 20 studies of 95783 individuals followed for 12.4 years. Diabetes Care 1999, 22:233-240. 10.2337/diacare.22.2.233, 10333939.
4. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414:813-820. 10.1038/414813a, 11742414.
5. Nishizawa T, Bornfeldt KE. Diabetic vascular disease and the potential role of macrophage glucose metabolism. Ann Med 2012, 44:555-563. 10.3109/07853890.2011.585346, 21679104.
6. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K. Immunobiology of dendritic cells. Annu Rev Immunol 2000, 18:767-811. 10.1146/annurev.immunol.18.1.767, 10837075.
7. Perrins CJ, Bobryshev YV. Current advances in understanding of immunopathology of atherosclerosis. Virchows Arch 2011, 458:117-123. 10.1007/s00428-010-1006-5, 21069384.
8. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. New Engl J Med 2005, 352:1685-1695. 10.1056/NEJMra043430, 15843671.
9. Bobryshev YV. Dendritic cells in atherosclerosis: current status of the problem and clinical relevance. Eur Heart J 2005, 26:1700-1704. 10.1093/eurheartj/ehi282, 15855191.
10. Nickel T, Schmauss D, Hanssen H, Sicic Z, Krebs B, Jankl S, Summo C, Fraunberger P, Walli AK, Pfeiler S, Weis M. oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation. Atherosclerosis 2009, 205:442-450. 10.1016/j.atherosclerosis.2009.01.002, 19203752.
11. Paulson KE, Zhu SN, Chen M, Nurmohamed S, Jongstra-Bilen J, Cybulsky MI. Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis. Circ Res 2010, 106:383-390. 10.1161/CIRCRESAHA.109.210781, 19893012.
12. Gautam S, Banerjee M. The macrophage Ox-LDL receptor, CD36 and its association with type II diabetes mellitus. Mol Genet Metab 2011, 102:389-398. 10.1016/j.ymgme.2010.12.012, 21262584.
13. Fukuhara-Takaki K, Sakai M, Sakamoto Y, Takeya M, Horiuchi S. Expression of class A scavenger receptor is enhanced by high glucose in vitro and under diabetic conditions in vivo: one mechanism for an increased rate of atherosclerosis in diabetes. J Biol Chem 2005, 280:3355-3364.
14. Li L, Sawamura T, Renier G. Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation. Circ Res 2004, 94:892-901. 10.1161/01.RES.0000124920.09738.26, 15001526.
15. Skov V, Knudsen S, Olesen M, Hansen ML, Rasmussen LM. Global gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes. Cardiovasc Diabetol 2012, 11:15. 10.1186/1475-2840-11-15, 3348024, 22340758.
16. Bornfeldt KE, Tabas I. Insulin Resistance, Hyperglycemia, and Atherosclerosis. Cell Metab 2011, 14:575-585. 10.1016/j.cmet.2011.07.015, 3217209, 22055501.
17. Ge J, Jia Q, Liang C, Huang D, Sun A, Wang K. Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells. Arterioscler Thromb Vasc Biol 2005, 25:2157-2163. 10.1161/01.ATV.0000181744.58265.63, 16100036.
18. Qian J, Lu H, Yao K, Huang R, Sun A, Hao Y, Wang KQ, Zou YZ, Ge JB. The effect and mechanism of high concentration of insulin induced immune maturation of human monocyte-derived dendritic cells. Am J Cardiol 2007, 99(Suppl 8):93F-94F.
19. Koltsova EK, Ley K. How dendritic cells shape atherosclerosis. Trends Immunol 2011, 32:540-547. 10.1016/j.it.2011.07.001, 3442786, 21835696.
20. Cybulsky MI, Jongstra-Bilen J. Resident intimal dendritic cells and the initiation of atherosclerosis. Curr Opin Lipidol 2010, 21:397-403. 10.1097/MOL.0b013e32833ded96, 20720490.
21. Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol 2010, 11:155-161. 10.1038/ni.1836, 2809046, 20037584.
22. Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res 2011, 108:235-248. 10.1161/CIRCRESAHA.110.223875, 3075542, 21252151.
23. Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, Tanaka T, Miwa S, Katsura Y, Kita T, Masaki T. An endothelial receptor for oxidized low-density lipoprotein. Nature 1997, 386:73-77. 10.1038/386073a0, 9052782.
24. Yoshida H, Kondratenko N, Green S, Steinberg D, Quehenberger O. Identification of the lectinlike receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor. Biochem J 1998, 334:9-13. 1219654, 9693095.
25. Chen M, Kakutani M, Naruko T, Ueda M, Narumiya S, Masaki T, Sawamura T. Activation-dependent surface expression of LOX-1 in human platelets. Biochem Biophys Res Commun 2001, 282:153-158. 10.1006/bbrc.2001.4516, 11263985.
26. Nahmod KA, Vermeulen ME, Raiden S, Salamone G, Gamberale R, Fernández-Calotti P, Alvarez A, Nahmod V, Giordano M, Geffner JR. Control of dendritic cell differentiation by angiotensin II. FASEB J 2003, 17:491-493.
27. Farhangkhoee H, Khan ZA, Barbin Y, Chakrabarti S. Glucose-induced up-regulation of CD36 mediates oxidative stress and microvascular endothelial cell dysfunction. Diabetologia 2005, 48:1401-1410. 10.1007/s00125-005-1801-8, 15915335.
28. Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 2002, 23:599-622. 10.1210/er.2001-0039, 12372842.
29. Bobryshev YV, Lord RS. Expression of heat shock protein-70 by dendritic cells in the arterial intima and its potential significance in atherogenesis. J Vasc Surg 2002, 35:368-375. 10.1067/mva.2002.121067, 11854737.
30. Yao K, Lu H, Huang R, Zhang S, Hong X, Shi H, Sun A, Qian J, Zou Y, Ge J. Changes of dendritic cells and fractalkine in type 2 diabetic patients with unstable angina pectoris: a preliminary report. Cardiovasc Diabetol 2011, 10:50. 10.1186/1475-2840-10-50, 3135516, 21658276.
31. Yin Y, Liu W, Ji G, Dai Y. The essential role of p38 MAPK in mediating the interplay of oxLDL and IL-10 in regulating endothelial cell apoptosis. Eur J Cell Biol 2013, 92:150-159. 10.1016/j.ejcb.2013.01.001, 23498167.
32. Maier W, Altwegg LA, Corti R, Gay S, Hersberger M, Maly FE, Sütsch G, Roffi M, Neidhart M, Eberli FR, Tanner FC, Gobbi S, von Eckardstein A, Lüscher TF. Inflammatory markers at the site of ruptured plaque in acute myocardial infarction: locally increased interleukin-6 and serum amyloid A but decreased C-reactive protein. Circulation 2005, 111:1355-1361. 10.1161/01.CIR.0000158479.58589.0A, 15753219.
33. Folcik VA, Aamir R, Cathcart MK. Cytokine modulation of LDL oxidation by activated human monocytes. Arterioscler Thromb Vasc Biol 1997, 17:1954-1961. 10.1161/01.ATV.17.10.1954, 9351359.
34. Zhang X, Niessner A, Nakajima T, Ma-Krupa W, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM. Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. Circ Res 2006, 98:524-531. 10.1161/01.RES.0000204452.46568.57, 16424368.