Significant differences in cell-cell fusion and viral entry between strains revealed by scanning mutagenesis of the C-heptad repeat of HIV gp41

Biochemistry

Volumn 52, Issue 20, 2013, Pages 3552-3563

  Diaz Aguilar, Barbara ^a   DeWispelaere, Karen ^a   Yi, Hyun Ah ^a   Jacobs, Amy ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE SUBSTITUTION; ALANINE-SCANNING MUTAGENESIS; AMINO ACID RESIDUES; EXTRACELLULAR DOMAINS; MUTATIONAL EFFECTS; PROTEOLYTIC PROCESSING; SIGNIFICANT DIFFERENCES; TRANS-MEMBRANE DOMAINS;

ACTIVATION ANALYSIS; AMINO ACIDS; CELL MEMBRANES; ENZYME ACTIVITY; MUTAGENESIS;

CYTOLOGY;

ALANINE; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41;

ALANINE SCANNING MUTAGENESIS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; C TERMINAL HEPTAD REPEAT; CARBOXY TERMINAL SEQUENCE; CELL CELL FUSION; CELL FUSION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS STRAIN;

CELL FUSION; HEK293 CELLS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MEMBRANE FUSION; MUTATION; RECEPTORS, CXCR4; VIRUS INTERNALIZATION;

EID: 84878236579     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400201h     Document Type: Article

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