Physalin a induces apoptotic cell death and protective autophagy in HT1080 human fibrosarcoma cells

Journal of Natural Products

Volumn 76, Issue 5, 2013, Pages 880-888

  He, Hao ^a   Zang, Ling He ^a   Feng, Yong Sheng ^a   Wang, Jian ^a   Liu, Wei Wei ^a   Chen, Li Xia ^a   Kang, Ning ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^c   Qiu, Feng ^a   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Institute for Clinical and Biomedical Sciences   (Japan)

^c SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; BECLIN 1; CASPASE 3; CASPASE 8; CASPASE 9; DEATH RECEPTOR; FLUOROURACIL; PACLITAXEL; PHYSALIN A; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; RAPAMYCIN; UNCLASSIFIED DRUG; WITHANOLIDE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; FIBROSARCOMA; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION; SARCOMA CELL; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; MEMBRANE PROTEINS; MOLECULAR STRUCTURE; PHYSALIS; WITHANOLIDES;

EID: 84878232596     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400017k     Document Type: Article

References (27)

1. Qiu, L.; Zhao, F.; Jiang, Z. H.; Chen, L. X.; Zhao, Q.; Liu, H. X.; Yao, X. S.; Qiu, F. J. Nat. Prod. 2008, 71, 642-646
2. Chinese Pharmacopoeia Committee. The Pharmacopoeia of People's Republic of China (Vol. 1); China Medical Science Press: Beijing, 2010; pp 337-338.
3. Soares, M. B.; Bellintani, M. C.; Ribeiro, I. M.; Tomassini, T. C.; Ribeiro dos Santos, R. Eur. J. Pharmacol. 2003, 459, 107-112
4. Sá, M. S.; de Menezes, M. N.; Krettli, A. U.; Ribeiro, I. M.; Tomassini, T. C.; Ribeiro dos Santos, R.; de Azevedo, W. F., Jr.; Soares, M. B. J. Nat. Prod. 2011, 74, 2269-2272
5. Brustolim, D.; Vasconcelos, J. F.; Freitas, L. A.; Teixeira, M. M.; Farias, M. T.; Ribeiro, Y. M.; Tomassini, T. C.; Oliveira, G. G.; Pontes de Carvalho, L. C.; Ribeiro dos Santos, R.; Soares, M. B. J. Nat. Prod. 2010, 73, 1323-1326
6. Damu, A. G.; Kuo, P. C.; Su, C. R.; Kuo, T. H.; Chen, T. H.; Bastow, K. F.; Lee, K. H.; Wu, T. S. J. Nat. Prod. 2007, 70, 1146-1152
7. Han, H. Y.; Qiu, L.; Wang, X. H.; Qiu, F.; Wong, Y. C.; Yao, X. S. Biol. Pharm. Bull. 2011, 34, 1584-1588
8. Orbach, D.; Rey, A.; Cecchetto, G.; Oberlin, O.; Casanova, M.; Thebaud, E.; Scopinaro, M.; Bisogno, G.; Carli, M.; Ferrari, A. J. Clin. Oncol. 2010, 28, 318-323
9. Cecchetto, G.; Carli, M.; Alaggio, R.; Dall'Igna, P.; Bisogno, G.; Scarzello, G.; Zanetti, I.; Durante, G.; Inserra, A.; Siracusa, F.; Guglielmi, M. J. Surg. Oncol. 2001, 78, 225-231
10. Savill, J.; Fadok, V. A. Nature 2000, 407, 784-788
11. Gerl, R.; Vaux, D. L. Carcinogenesis 2005, 26, 263-270
12. Hengartner, M. O. Nature 2000, 407, 770-776
13. Johnstone, R. W.; Ruefli, A. A.; Lowe, S. W. Cell 2002, 108, 153-164
14. Kothakota, S.; Azuma, T.; Reinhard, C.; Klippel, A.; Tang, J.; Chu, K.; McGarry, T. J.; Kirschner, M. W.; Koths, K.; Kwiatkowski, D. J.; Williams, L. T. Science 1997, 278, 294-298
15. Martinou, J. C.; Green, D. R. Nat. Rev. Mol. Cell Biol. 2001, 2, 63-67
16. Wang, X. Genes Dev. 2001, 15, 2922-2933
17. Finkel, T.; Serrano, M.; Blasco, M. A. Nature 2007, 448, 767-774
18. Eisenberg-Lerner, A.; Bialik, S.; Simon, H. U.; Kimchi, A. Cell Death Differ. 2009, 16, 966-975
19. Pliyev, B. K.; Menshikov, M. Apoptosis 2012, 17, 1050-1065
20. Kang, N.; Zhang, J. H.; Qiu, F.; Chen, S.; Tashiro, S.; Onodera, S.; Ikejima, T. J. Nat. Prod. 2010, 73, 1058-1063
21. Zhang, Y. H.; Wu, Y. L.; Cheng, Y.; Zhao, Z. K.; Tashiro, S.; Onodera, S.; Ikejima, T. Biochem. Biophys. Res. Commun. 2008, 377, 1205-1210
22. Mi, Y. C.; Thomas, S. D.; Xu, X. H.; Casson, L. K.; Miller, D. M.; Bates, P. J. J. Biol. Chem. 2003, 278, 8572-8579
23. Sakahira, H.; Enari, M.; Nagata, S. J. Biol. Chem. 1999, 274, 15740-15744
24. Kawai, M.; Ogura, T.; Makino, B.; Matsumoto, A.; Yamamura, H.; Butsugan, Y.; Hayashi, M. Phytochemistry 1992, 31, 4299-4302
25. Bigaud, M.; Maurer, C.; Vedrine, C.; Puissant, B.; Blancher, A. J. Pharmacol. Toxicol. Methods 2004, 50, 153-159
26. Nilsson, C.; Aboud, S.; Karlén, K.; Hejdeman, B.; Urassa, W.; Biberfeld, G. Clin. Vaccine Immunol. 2008, 15, 585-589
27. Biederbick, A.; Kern, H. F.; Elsasser, H. P. Eur. J. Cell Biol. 1995, 66, 3-14