-
1
-
-
79957621253
-
The insider's guide to leukocyte integrin signalling and function
-
Hogg, N., Patzak, I., and Willenbrock, F. (2011) The insider's guide to leukocyte integrin signalling and function. Nat. Rev. Immunol. 11, 416-426
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 416-426
-
-
Hogg, N.1
Patzak, I.2
Willenbrock, F.3
-
2
-
-
47149093727
-
A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development
-
Chen, Y., Yu, M., Podd, A., Wen, R., Chrzanowska-Wodnicka, M., White, G. C., and Wang, D. (2008) A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. Blood 111, 4627-4636
-
(2008)
Blood
, vol.111
, pp. 4627-4636
-
-
Chen, Y.1
Yu, M.2
Podd, A.3
Wen, R.4
Chrzanowska-Wodnicka, M.5
White, G.C.6
Wang, D.7
-
3
-
-
0038561221
-
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
-
DOI 10.1083/jcb.200301133
-
Shimonaka, M., Katagiri, K., Nakayama, T., Fujita, N., Tsuruo, T., Yoshie, O., and Kinashi, T. (2003) Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. J. Cell Biol. 161, 417-427 (Pubitemid 36529858)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.2
, pp. 417-427
-
-
Shimonaka, M.1
Katagiri, K.2
Nakayama, T.3
Fujita, N.4
Tsuruo, T.5
Yoshie, O.6
Kinashi, T.7
-
4
-
-
78650661837
-
Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen
-
Manevich-Mendelson, E., Grabovsky, V., Feigelson, S. W., Cinamon, G., Gore, Y., Goverse, G., Monkley, S. J., Margalit, R., Melamed, D., Mebius, R. E., Critchley, D. R., Shachar, I., and Alon, R. (2010) Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen. Blood 116, 5907-5918
-
(2010)
Blood
, vol.116
, pp. 5907-5918
-
-
Manevich-Mendelson, E.1
Grabovsky, V.2
Feigelson, S.W.3
Cinamon, G.4
Gore, Y.5
Goverse, G.6
Monkley, S.J.7
Margalit, R.8
Melamed, D.9
Mebius, R.E.10
Critchley, D.R.11
Shachar, I.12
Alon, R.13
-
5
-
-
70349565999
-
Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions
-
Manevich-Mendelson, E., Feigelson, S. W., Pasvolsky, R., Aker, M., Grabovsky, V., Shulman, Z., Kilic, S. S., Rosenthal-Allieri, M. A., Ben-Dor, S., Mory, A., Bernard, A., Moser, M., Etzioni, A., and Alon, R. (2009) Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. Blood 114, 2344-2353
-
(2009)
Blood
, vol.114
, pp. 2344-2353
-
-
Manevich-Mendelson, E.1
Feigelson, S.W.2
Pasvolsky, R.3
Aker, M.4
Grabovsky, V.5
Shulman, Z.6
Kilic, S.S.7
Rosenthal-Allieri, M.A.8
Ben-Dor, S.9
Mory, A.10
Bernard, A.11
Moser, M.12
Etzioni, A.13
Alon, R.14
-
7
-
-
18144426450
-
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes
-
DOI 10.1073/pnas.0502467102
-
Anikeeva, N., Somersalo, K., Sims, T. N., Thomas, V. K., Dustin, M. L., and Sykulev, Y. (2005) Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 102, 6437-6442 (Pubitemid 40617461)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.18
, pp. 6437-6442
-
-
Anikeeva, N.1
Somersalo, K.2
Sims, T.N.3
Thomas, V.K.4
Dustin, M.L.5
Sykulev, Y.6
-
8
-
-
79955780870
-
A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis
-
MacPherson, M., Lek, H. S., Prescott, A., and Fagerholm, S. C. (2011) A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis. J. Biol. Chem. 286, 17303-17310
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17303-17310
-
-
MacPherson, M.1
Lek, H.S.2
Prescott, A.3
Fagerholm, S.C.4
-
9
-
-
84860330197
-
Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues
-
Matthews, S. A., San Lek, H., Morrison, V. L., Mackenzie, M. G., Zarrouk, M., Cantrell, D., and Fagerholm, S. C. (2012) Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues. Eur. J. Immunol. 42, 1316-1326
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1316-1326
-
-
Matthews, S.A.1
San Lek, H.2
Morrison, V.L.3
Mackenzie, M.G.4
Zarrouk, M.5
Cantrell, D.6
Fagerholm, S.C.7
-
10
-
-
83755222547
-
Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots
-
Shulman, Z., Cohen, S. J., Roediger, B., Kalchenko, V., Jain, R., Grabovsky, V., Klein, E., Shinder, V., Stoler-Barak, L., Feigelson, S. W., Meshel, T., Nurmi, S. M., Goldstein, I., Hartley, O., Gahmberg, C. G., Etzioni, A., Weninger, W., Ben-Baruch, A., and Alon, R. (2012) Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots. Nat. Immunol. 13, 67-76
-
(2012)
Nat. Immunol.
, vol.13
, pp. 67-76
-
-
Shulman, Z.1
Cohen, S.J.2
Roediger, B.3
Kalchenko, V.4
Jain, R.5
Grabovsky, V.6
Klein, E.7
Shinder, V.8
Stoler-Barak, L.9
Feigelson, S.W.10
Meshel, T.11
Nurmi, S.M.12
Goldstein, I.13
Hartley, O.14
Gahmberg, C.G.15
Etzioni, A.16
Weninger, W.17
Ben-Baruch, A.18
Alon, R.19
-
11
-
-
70350523607
-
Phosphoinositide (3,4,5)-trisphosphate binding to phosphoinositide- dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation
-
Waugh, C., Sinclair, L., Finlay, D., Bayascas, J. R., and Cantrell, D. (2009) Phosphoinositide (3,4,5)-trisphosphate binding to phosphoinositide- dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation. Mol. Cell. Biol. 29, 5952-5962
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5952-5962
-
-
Waugh, C.1
Sinclair, L.2
Finlay, D.3
Bayascas, J.R.4
Cantrell, D.5
-
12
-
-
78751652828
-
Effects of disturbed flow on vascular endothelium: Pathophysiological basis and clinical perspectives
-
Chiu, J. J., and Chien, S. (2011) Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol. Rev. 91, 327-387
-
(2011)
Physiol. Rev.
, vol.91
, pp. 327-387
-
-
Chiu, J.J.1
Chien, S.2
-
13
-
-
77952687197
-
E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin αLβ2-mediated slow leukocyte rolling
-
Yago, T., Shao, B., Miner, J. J., Yao, L., Klopocki, A. G., Maeda, K., Coggeshall, K. M., and McEver, R. P. (2010) E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin αLβ2-mediated slow leukocyte rolling. Blood 116, 485-494
-
(2010)
Blood
, vol.116
, pp. 485-494
-
-
Yago, T.1
Shao, B.2
Miner, J.J.3
Yao, L.4
Klopocki, A.G.5
Maeda, K.6
Coggeshall, K.M.7
McEver, R.P.8
-
14
-
-
33846246384
-
Force as a Facilitator of Integrin Conformational Changes during Leukocyte Arrest on Blood Vessels and Antigen-Presenting Cells
-
DOI 10.1016/j.immuni.2007.01.002, PII S1074761307001021
-
Alon, R., and Dustin, M. L. (2007) Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity 26, 17-27 (Pubitemid 46109349)
-
(2007)
Immunity
, vol.26
, Issue.1
, pp. 17-27
-
-
Alon, R.1
Dustin, M.L.2
-
15
-
-
33749172382
-
The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1
-
DOI 10.1128/MCB.00331-06
-
Kliche, S., Breitling, D., Togni, M., Pusch, R., Heuer, K., Wang, X., Freund, C., Kasirer-Friede, A., Menasche, G., Koretzky, G. A., and Schraven, B. (2006) The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1. Mol. Cell. Biol. 26, 7130-7144 (Pubitemid 44477690)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.19
, pp. 7130-7144
-
-
Kliche, S.1
Breitling, D.2
Togni, M.3
Pusch, R.4
Heuer, K.5
Wang, X.6
Freund, C.7
Kasirer-Friede, A.8
Menasche, G.9
Koretzky, G.A.10
Schraven, B.11
-
16
-
-
1642578985
-
RhoA and ζ PKC Control Distinct Modalities of LFA-1 Activation by Chemokines: Critical Role of LFA-1 Affinity Triggering in Lymphocyte In Vivo Homing
-
DOI 10.1016/S1074-7613(03)00350-9
-
Giagulli, C., Scarpini, E., Ottoboni, L., Narumiya, S., Butcher, E. C., Constantin, G., and Laudanna, C. (2004) RhoA and ζ PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. Immunity 20, 25-35 (Pubitemid 38134291)
-
(2004)
Immunity
, vol.20
, Issue.1
, pp. 25-35
-
-
Giagulli, C.1
Scarpini, E.2
Ottoboni, L.3
Narumiya, S.4
Butcher, E.C.5
Constantin, G.6
Laudanna, C.7
-
17
-
-
84860335516
-
Protein kinase C-θ is required for murine neutrophil recruitment and adhesion strengthening under flow
-
Bertram, A., Zhang, H., von Vietinghoff, S., de Pablo, C., Haller, H., Shushakova, N., and Ley, K. (2012) Protein kinase C-θ is required for murine neutrophil recruitment and adhesion strengthening under flow. J. Immunol. 188, 4043-4051
-
(2012)
J. Immunol.
, vol.188
, pp. 4043-4051
-
-
Bertram, A.1
Zhang, H.2
Von Vietinghoff, S.3
De Pablo, C.4
Haller, H.5
Shushakova, N.6
Ley, K.7
-
18
-
-
0035936848
-
An essential role for calmodulin in regulating human T cell aggregation
-
DOI 10.1016/S0014-5793(01)02182-2, PII S0014579301021822
-
Fagerholm, S. C., Prescott, A., Cohen, P., and Gahmberg, C. G. (2001) An essential role for calmodulin in regulating human T cell aggregation. FEBS Lett. 491, 131-136 (Pubitemid 32172017)
-
(2001)
FEBS Letters
, vol.491
, Issue.1-2
, pp. 131-136
-
-
Fagerholm, S.C.1
Prescott, A.2
Cohen, P.3
Gahmberg, C.G.4
-
19
-
-
33846027057
-
Phospholipase C, calcium, and calmodulin are critical for α4β1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants
-
DOI 10.1182/blood-2006-01-029199
-
Hyduk, S. J., Chan, J. R., Duffy, S. T., Chen, M., Peterson, M. D., Waddell, T. K., Digby, G. C., Szaszi, K., Kapus, A., and Cybulsky, M. I. (2007) Phospholipase C, calcium, and calmodulin are critical for α4β1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood 109, 176-184 (Pubitemid 46053059)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 176-184
-
-
Hyduk, S.J.1
Chan, J.R.2
Duffy, S.T.3
Chen, M.4
Peterson, M.D.5
Waddell, T.K.6
Digby, G.C.7
Szaszi, K.8
Kapus, A.9
Cybulsky, M.I.10
-
20
-
-
11144355979
-
Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1
-
Sánchez-Martín, L., Sánchez-Sánchez, N., Gutiérrez-López, M. D., Rojo, A. I., Vicente-Manzanares, M., Pérez-Alvarez, M. J., Sánchez-Mateos, P., Bustelo, X. R., Cuadrado, A., Sánchez-Madrid, F., Rodríguez-Fernández, J. L., and Cabañas, C. (2004) Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1. J. Biol. Chem. 279, 16194-16205
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16194-16205
-
-
Sánchez-Martín, L.1
Sánchez-Sánchez, N.2
Gutiérrez-López, M.D.3
Rojo, A.I.4
Vicente-Manzanares, M.5
Pérez-Alvarez, M.J.6
Sánchez-Mateos, P.7
Bustelo, X.R.8
Cuadrado, A.9
Sánchez-Madrid, F.10
Rodríguez-Fernández, J.L.11
Cabañas, C.12
-
21
-
-
33744955342
-
2 in an intermediate affinity state
-
DOI 10.1074/jbc.M512472200
-
Salas, A., Shimaoka, M., Phan, U., Kim, M., and Springer, T. A. (2006) Transition from rolling to firm adhesion can be mimicked by extension of integrin αLβ2 in an intermediate affinity state. J. Biol. Chem. 281, 10876-10882 (Pubitemid 43855510)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.16
, pp. 10876-10882
-
-
Salas, A.1
Shimaoka, M.2
Phan, U.3
Kim, M.4
Springer, T.A.5
-
22
-
-
79953090989
-
The integrin LFA-1 signals through ZAP-70 to regulate expression of high-affinity LFA-1 on T lymphocytes
-
Evans, R., Lellouch, A. C., Svensson, L., McDowall, A., and Hogg, N. (2011) The integrin LFA-1 signals through ZAP-70 to regulate expression of high-affinity LFA-1 on T lymphocytes. Blood 117, 3331-3342
-
(2011)
Blood
, vol.117
, pp. 3331-3342
-
-
Evans, R.1
Lellouch, A.C.2
Svensson, L.3
McDowall, A.4
Hogg, N.5
-
23
-
-
33845401235
-
Leukocyte phosphoinositide-3 kinase γ is required for chemokine-induced, sustained adhesion under flow in vivo
-
DOI 10.1189/jlb.0306227
-
Smith, D. F., Deem, T. L., Bruce, A. C., Reutershan, J., Wu, D., and Ley, K. (2006) Leukocyte phosphoinositide-3 kinase γ is required for chemokine-induced, sustained adhesion under flow in vivo. J. Leukoc. Biol. 80, 1491-1499 (Pubitemid 44904988)
-
(2006)
Journal of Leukocyte Biology
, vol.80
, Issue.6
, pp. 1491-1499
-
-
Smith, D.F.1
Deem, T.L.2
Bruce, A.C.3
Reutershan, J.4
Wu, D.5
Ley, K.6
-
24
-
-
38349188189
-
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation
-
Yin, H., Stojanovic, A., Hay, N., and Du, X. (2008) The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood 111, 658-665
-
(2008)
Blood
, vol.111
, pp. 658-665
-
-
Yin, H.1
Stojanovic, A.2
Hay, N.3
Du, X.4
-
25
-
-
4043082729
-
Cuttin edge: Differential roles for phosphoinositide 3-kinases, p110γ and p110γ, lymphocyte chemotaxis and homing
-
Reif, K., Okkenhaug, K., Sasaki, T., Penninger, J. M., Vanhaesebroeck, B., and Cyster, J. G. (2004) Cutting edge: differential roles for phosphoinositide 3-kinases, p110γ and p110δ, in lymphocyte chemotaxis and homing. J. Immunol. 173, 2236-2240 (Pubitemid 39063077)
-
(2004)
Journal of Immunology
, vol.173
, Issue.4
, pp. 2236-2240
-
-
Reif, K.1
Okkenhaug, K.2
Sasaki, T.3
Penninger, J.M.4
Vanhaesebroeck, B.5
Cyster, J.G.6
-
26
-
-
84867887799
-
Chemokine-triggered leukocyte arrest: Force-regulated bi-directional integrin activation in quantal adhesive contacts
-
Alon, R., and Feigelson, S. W. (2012) Chemokine-triggered leukocyte arrest: force-regulated bi-directional integrin activation in quantal adhesive contacts. Curr. Opin. Cell Biol. 24, 670-676
-
(2012)
Curr. Opin. Cell Biol.
, vol.24
, pp. 670-676
-
-
Alon, R.1
Feigelson, S.W.2
-
27
-
-
0034235394
-
The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment
-
Sigal, A., Bleijs, D. A., Grabovsky, V., van Vliet, S. J., Dwir, O., Figdor, C. G., van Kooyk, Y., and Alon, R. (2000) The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment. J. Immunol. 165, 442-452 (Pubitemid 30429538)
-
(2000)
Journal of Immunology
, vol.165
, Issue.1
, pp. 442-452
-
-
Sigal, A.1
Bleijs, D.A.2
Grabovsky, V.3
Van Vliet, S.J.4
Dwir, O.5
Figdor, C.G.6
Van Kooyk, Y.7
Alon, R.8
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