Factor VIIIa A2 subunit shows a high affinity interaction with factor IXa: Contribution of A2 subunit residues 707-714 to the interaction with factor IXa

Journal of Biological Chemistry

Volumn 288, Issue 21, 2013, Pages 15057-15064

  Griffiths, Amy E ^a   Rydkin, Ivan ^a   Fay, Philip J ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS;

ACTIVE SITE; AFFINITY INTERACTIONS; ALANINE SUBSTITUTION; BACULOVIRUS; ENZYME COMPLEXES; FACTOR IXA; FACTOR VIIIA; HIGH AFFINITY; NUMBER OF CONTACTS; SURFACE-PLASMON RESONANCE;

SURFACE PLASMON RESONANCE;

ALANINE; ASPARTIC ACID; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9A; LYSINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BINDING AFFINITY; BIOTINYLATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN SUBUNIT; SURFACE PLASMON RESONANCE; WILD TYPE;

EID: 84878221053     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.456467     Document Type: Article

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