P38 Mitogen-activated protein kinase regulates nuclear receptor CAR that activates the CYP2B6 gene

Drug Metabolism and Disposition

Volumn 41, Issue 6, 2013, Pages 1170-1173

  Saito, Kosuke ^a   Moore, Rick ^a   Negishi, Masahiko ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; GLUCURONOSYLTRANSFERASE 1A1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYP2A7 GENE; CYP2C9 GENE; CYP3A4 GENE; CYTOCHROME P450 2B6 GENE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GENE; GENE ACTIVATION; GENE CONTROL; GENE INDUCTION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIGAND BINDING; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UGT1A1 GENE;

ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; ENZYME ACTIVATION; FEMALE; HEP G2 CELLS; HEPATOCYTES; HUMANS; MALE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER;

EID: 84878215916     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.051623     Document Type: Article

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