Short- and Long-Term Effects of Interleukin-2 Treatment on the Sensitivity of Periadolescent Female Mice to Interleukin-2 and Dopamine Uptake Inhibitor

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Rankin, James S ^a   Zalcman, Steven S ^a   Zhu, Youhua ^a   Siegel, Allan ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE UPTAKE INHIBITOR; INTERLEUKIN 2; VANOXERINE; DOPAMINE;

ADOLESCENT; ADULT ANIMAL; ADULTHOOD; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINE UPTAKE; EXPLORATORY BEHAVIOR; FEMALE; JUMPING; LOCOMOTION; MOUSE; NONHUMAN; PROTEIN FUNCTION; REARING; STEREOTYPY; ANIMAL; BRAIN; DRUG EFFECTS; MALE; METABOLISM; MOTOR ACTIVITY; TIME;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; FEMALE; INTERLEUKIN-2; MALE; MICE; MOTOR ACTIVITY; TIME FACTORS;

EID: 84878162481     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064473     Document Type: Article

References (46)

1. Stewart J, Kolb B, (1988) The effects of neonatal gonadectomy and prenatal stress on cortical thickness and asymmetry in rats. Behav Neural Biol 49: 344-360.
2. Mirnics K, Middleton FA, Lewis DA, Levitt P, (2001) Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci 24: 479-486.
3. Paus T, Keshavan M, Giedd JN, (2008) Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 9: 947-957 doi:10.1038/nrn2513.
4. Rolls ET, Deco G, (2011) A computational neuroscience approach to schizophrenia and its onset. Neurosci Biobehav Rev 35: 1644-1653 doi:10.1016/j.neubiorev.2010.09.001.
5. Faludi G, Mirnics K, (2011) Synaptic changes in the brain of subjects with schizophrenia. Int J Dev Neurosci 29: 305-309 doi:10.1016/j.ijdevneu.2011.02.013.
6. Laviola G, Macrì S, Morley-Fletcher S, Adriani W, (2003) Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence. Neurosci Biobehav Rev 27: 19-31.
7. Adriani W, Laviola G, (2004) Windows of vulnerability to psychopathology and therapeutic strategy in the adolescent rodent model. Behav Pharmacol 15: 341-352.
8. Smith RF, (2003) Animal models of periadolescent substance abuse. Neurotoxicol Teratol 25: 291-301.
9. Nawa H, Takei N, (2006) Recent progress in animal modeling of immune inflammatory processes in schizophrenia: implication of specific cytokines. Neurosci Res 56: 2-13 doi:10.1016/j.neures.2006.06.002.
10. Watanabe Y, Someya T, Nawa H, (2010) Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models. Psychiatry Clin Neurosci 64: 217-230 doi:10.1111/j.1440-1819.2010.02094.x.
11. De Araujo EG, Da Silva GM, Dos Santos AA, (2009) Neuronal cell survival: the role of interleukins. Ann N Y Acad Sci 1153: 57-64 doi:10.1111/j.1749-6632.2008.03974.x.
12. McAfoose J, Baune BT, (2009) Evidence for a cytokine model of cognitive function. Neurosci Biobehav Rev 33: 355-366 doi:10.1016/j.neubiorev.2008.10.005.
13. Zalcman S, Green-Johnson JM, Murray L, Wan W, Nance DM, et al. (1994) Interleukin-2-induced enhancement of an antigen-specific IgM plaque-forming cell response is mediated by the sympathetic nervous system. J Pharmacol Exp Ther 271: 977-982.
14. Zalcman S, Murray L, Dyck DG, Greenberg AH, Nance DM, (1998) Interleukin-2 and-6 induce behavioral-activating effects in mice. Brain Res 811: 111-121.
15. Zalcman SS, Patel A, Mohla R, Zhu Y, Siegel A, (2012) Soluble cytokine receptors (sIL-2Rα, sIL-2Rβ) induce subunit-specific behavioral responses and accumulate in the cerebral cortex and basal forebrain. PLoS ONE 7: e36316 doi:10.1371/journal.pone.0036316.
16. Kerr D, Krishnan C, Pucak ML, Carmen J, (2005) The immune system and neuropsychiatric diseases. Int Rev Psychiatry 17: 443-449 doi:10.1080/0264830500381435.
17. Ga{ogonek}dek-Michalska A, Bugajski J, (2010) Interleukin-1 (IL-1) in stress-induced activation of limbic-hypothalamic-pituitary adrenal axis. Pharmacol Rep 62: 969-982.
18. Bilbo SD, Schwarz JM, (2012) The immune system and developmental programming of brain and behavior. Front Neuroendocrinol 33: 267-286 doi:10.1016/j.yfrne.2012.08.006.
19. Zalcman SS, (2001) Interleukin-2 potentiates novelty- and GBR 12909-induced exploratory activity. Brain Res 899: 1-9.
20. Brown KA, (2001) Factors modifying the migration of lymphocytes across the blood-brain barrier. Int Immunopharmacol 1: 2043-2062.
21. Banks WA, Niehoff ML, Ponzio NM, Erickson MA, Zalcman SS, (2012) Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice. J Neuroinflammation 9: 231 doi:10.1186/1742-2094-9-231.
22. Bhatt S, Zalcman S, Hassanain M, Siegel A, (2005) Cytokine modulation of defensive rage behavior in the cat: role of GABAA and interleukin-2 receptors in the medial hypothalamus. Neuroscience 133: 17-28 doi:10.1016/j.neuroscience.2005.01.065.
23. Bhatt S, Siegel A, (2006) Potentiating role of interleukin 2 (IL-2) receptors in the midbrain periaqueductal gray (PAG) upon defensive rage behavior in the cat: role of neurokinin NK(1) receptors. Behav Brain Res 167: 251-260 doi:10.1016/j.bbr.2005.09.011.
24. Karrenbauer BD, Ho Y-J, Ludwig V, Löhn J, Spanagel R, et al. (2009) Time-dependent effects of striatal interleukin-2 on open field behaviour in rats. J Neuroimmunol 208: 10-18 doi:10.1016/j.jneuroim.2008.12.003.
25. Ikemoto S, (2002) Ventral striatal anatomy of locomotor activity induced by cocaine, D-amphetamine, dopamine and D1/D2 agonists. Neuroscience 113: 939-955.
26. Saetre P, Emilsson L, Axelsson E, Kreuger J, Lindholm E, et al. (2007) Inflammation-related genes up-regulated in schizophrenia brains. BMC Psychiatry 7: 46 doi:10.1186/1471-244X-7-46.
27. Rawdin B, Mellon SH, Dhabhar FS, Epel ES, Puterman E, et al. (2012) Dysregulated relationship of inflammation and oxidative stress in major depression. Brain Behav Immun. doi:10.1016/j.bbi.2012.11.011.
28. Stertz L, Magalhães PVS, Kapczinski F, (2013) Is bipolar disorder an inflammatory condition? The relevance of microglial activation. Curr Opin Psychiatry 26: 19-26 doi:10.1097/YCO.0b013e32835aa4b4.
29. Karson A, Demirtaş T, Bayramgürler D, Balci{dotless} F, Utkan T (2012) Chronic Administration of Infliximab (TNF-Alpha Inhibitor) Decreases Depression and Anxiety-like Behaviour in Rat Model of Chronic Mild Stress. Basic Clin Pharmacol Toxicol. doi:10.1111/bcpt.12037.
30. Elamin I, Edwards MJ, Martino D (2012) Immune dysfunction in Tourette syndrome. Behav Neurol. doi:10.3233/BEN-120295.
31. Angelidou A, Asadi S, Alysandratos K-D, Karagkouni A, Kourembanas S, et al. (2012) Perinatal stress, brain inflammation and risk of autism-Review and proposal. BMC Pediatr 12: 89 doi:10.1186/1471-2431-12-89.
32. Nance DM, Sanders VM, (2007) Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav Immun 21: 736-745 doi:10.1016/j.bbi.2007.03.008.
33. Sanders VM, Straub RH, (2002) Norepinephrine, the beta-adrenergic receptor, and immunity. Brain Behav Immun 16: 290-332.
34. Rook GAW, Lowry CA, (2008) The hygiene hypothesis and psychiatric disorders. Trends Immunol 29: 150-158 doi:10.1016/j.it.2008.01.002.
35. Igue R, Potvin S, Bah R, Stip E, Bouchard R-H, et al. (2011) Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia-spectrum disorders. Prog Neuropsychopharmacol Biol Psychiatry 35: 1695-1698 doi:10.1016/j.pnpbp.2011.05.011.
36. Stephan AH, Barres BA, Stevens B, (2012) The complement system: an unexpected role in synaptic pruning during development and disease. Annu Rev Neurosci 35: 369-389 doi:10.1146/annurev-neuro-061010-113810.
37. Marra C, Gomes Moret D, De Souza Corrêa A, Chagas da Silva F, Moraes P, et al. (2011) Protein kinases JAK and ERK mediate protective effect of interleukin-2 upon ganglion cells of the developing rat retina. J Neuroimmunol 233: 120-126 doi:10.1016/j.jneuroim.2010.12.008.
38. Shen Y, Liu S-S, Zhan M-Y, Luo J-H, Zhu L-J, (2010) Interleukin-2 enhances dendritic development and spinogenesis in cultured hippocampal neurons. Anat Rec (Hoboken) 293: 1017-1023 doi:10.1002/ar.21118.
39. Zhang D, Patel A, Zhu Y, Siegel A, Zalcman SS, (2012) Anti-streptococcus IgM antibodies induce repetitive stereotyped movements: cell activation and co-localization with Fcα/μ receptors in the striatum and motor cortex. Brain Behav Immun 26: 521-533 doi:10.1016/j.bbi.2012.01.005.
40. Hanisch UK, Quirion R, (1995) Interleukin-2 as a neuroregulatory cytokine. Brain Res Brain Res Rev 21: 246-284.
41. Kazakova TB, Barabanova SV, Novikova NS, Glushikhina MS, Khavinson VK, et al. (2005) Synthesis of IL-2 mRNA in cells of rat hypothalamic structures after injection of short peptides. Bull Exp Biol Med 139: 718-720.
42. Korneva EA, Barabanova SV, Golovko OI, Nosov MA, Novikova NS, et al. (2000) C-fos and IL-2 gene expression in rat brain cells and splenic lymphocytes after nonantigenic and antigenic stimuli. Ann N Y Acad Sci 917: 197-209.
43. Bhatt S, Bhatt R, Zalcman SS, Siegel A, (2008) Role of IL-1 beta and 5-HT2 receptors in midbrain periaqueductal gray (PAG) in potentiating defensive rage behavior in cat. Brain Behav Immun 22: 224-233 doi:10.1016/j.bbi.2007.07.011.
44. Schwarz JM, Bilbo SD, (2012) Sex, glia, and development: interactions in health and disease. Horm Behav 62: 243-253 doi:10.1016/j.yhbeh.2012.02.018.
45. Duchesne A, Dufresne MM, Sullivan RM, (2009) Sex differences in corticolimbic dopamine and serotonin systems in the rat and the effect of postnatal handling. Prog Neuropsychopharmacol Biol Psychiatry 33: 251-261 doi:10.1016/j.pnpbp.2008.11.012.
46. Camacho-Arroyo I, López-Griego L, Morales-Montor J, (2009) The role of cytokines in the regulation of neurotransmission. Neuroimmunomodulation 16: 1-12 doi:10.1159/000179661.