Modal gating of GluN1/GluN2D NMDA receptors

Neuropharmacology

Volumn 71, Issue , 2013, Pages 184-190

  Vance, Katie M ^a   Hansen, Kasper B ^a   Traynelis, Stephen F ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electrophysiology; Ionotropic glutamate receptors; NR2D; Single channel recordings

Indexed keywords

GLUN1 PROTEIN; GLUN2D PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MEMBRANE CONDUCTANCE; MODAL GATING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; VOLTAGE CLAMP;

ANIMALS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; KINETICS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RECOMBINANT PROTEINS;

EID: 84878158561     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.03.018     Document Type: Article

References (66)

1. A. Alt, B. Weiss, A.M. Ogden, J.L. Knauss, J. Oler, K. Ho, T.H. Large, and D. Bleakman Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro Neuropharmacology 46 6 2004 793 806
2. S.A. Amico-Ruvio, and G.K. Popescu Stationary gating of GluN1/GluN2B receptors in intact membrane patches Biophys. J. 98 7 2010 1160 1169
3. + channel and effects of coexpression of the beta(1)-subunit Biophys. J. 70 6 1996 2581 2592
4. P. Chavis, and G. Westbrook Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse Nature 411 6835 2001 317 321
5. R.J. Clarke, and J.W. Johnson NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock J. Neurosci. 26 21 2006 5825 5834
6. D. Colquhoun, and A. Hawkes Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed Proc. R Soc. Lond., B Biol. Sci. 240 1299 1990 453 457
7. D. Colquhoun, and F. Sigworth Fitting and statistical analysis of single-channel records B. Sakmann, E. Neher, Single-channel Recording 1995 Plenum Press New York, NY 483 587
8. A.H. Delcour, D. Lipscombe, and R.W. Tsien Multiple modes of N-type calcium channel activity distinguished by differences in gating kinetics J. Neurosci. 13 1 1993 181 194
9. S.M. Dravid, A. Prakash, and S.F. Traynelis Activation of recombinant NR1/NR2C NMDA receptors J. Physiol. 586 18 2008 4425 4439
10. A.W. Dunah, R.P. Yasuda, Y.-H. Wang, J. Luo, M.I. Dávila- García, M. Gbadegesin, S. Vicini, and B.B. Wolfe Regional and ontogenic expression of the NMDA receptor subunit NR2D protein in rat brain using a subunit-specific antibody J. Neurochem. 67 6 1996 2335 2345
11. I. Dzhura, Y.J. Wu, R.J. Colbran, J.R. Balser, and M.E. Anderson Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels Nat. Cell Biol. 2 3 2000 173 177
12. M.D. Ehlers, S. Zhang, J.P. Bernhardt, and R.L. Huganir Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit Cell 84 5 1996 745 755
13. M.D. Ehlers, E.T. Fung, R.J. O'Brien, and R.L. Huganir Splice variant-specific interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments J. Neurosci. 18 2 1998 720 730
14. K. Erreger, S.M. Dravid, T.G. Banke, D.J.A. Wyllie, and S.F. Traynelis Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles J. Physiol. 563 2 2005 345 358
15. T. Fellin, S. Luvisetto, M. Spagnolo, and D. Pietrobon Modal gating of human Ca(v)2.1 (P/Q-type) calcium channels: II. The b mode and reversible uncoupling of inactivation J. Gen. Physiol. 124 5 2004 463 474
16. A.J. Gibb, and D. Colquhoun Glutamate activation of a single NMDA receptor-channel produces a cluster of channel openings Proc. Biol. Sci. 243 1306 1991 39 45
17. M. Gielen, B.S. Retchless, L. Mony, J.W. Johnson, and P. Paoletti Mechanism of differential control of NMDA receptor activity by NR2 subunits Nature 459 7247 2009 703 707
18. D.J. Goebel, and M.S. Poosch NMDA receptor subunit gene expression in the rat brain: a quantitative analysis of endogenous mRNA levels of NR1Com, NR2A, NR2B, NR2C, NR2D and NR3A Mol. Brain Res. 69 2 1999 164 170
19. 2+ current facilitation: a modeling study Biophys. J. 96 5 2009 1770 1785
20. P. Hess, and R.W. Tsien Mechanism of ion permeation through calcium channels Nature 309 5967 1984 453 456
21. M. Hollmann, J. Boulter, C. Maron, L. Beasley, J. Sullivan, G. Pecht, and S. Heinemann Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor Neuron 10 5 1993 943 954
22. J.R. Howe, D. Colquhoun, and S.G. Cullcandy On the kinetics of large-conductance glutamate receptor ion channels in rat cerebellar granule neurons Proc. Royal Soc. B Biol. Sci. 233 1273 1988 407 422
23. J.R. Howe, S.G. Cull-Candy, and D. Colquhoun Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells J. Physiol. 432 1 1991 143 202
24. J.R. Howe, and J.M. Ritchie Multiple kinetic components of sodium channel inactivation in rabbit Schwann cells J. Physiol. 455 1 1992 529 566
25. 2+ channels Neuron 12 6 1994 1301 1318
26. C.E. Jahr, and C.F. Stevens Glutamate activates multiple single channel conductances in hippocampal neurons Nature 325 6104 1987 522 525
27. 2+-dependent inactivation of NMDA receptors J. Neurosci. 19 4 1999 1165 1178
28. 2+ block in NMDA receptor channels J. Neurosci. 16 11 1996 3549 3558
29. C.L. Kussius, and G.K. Popescu Kinetic basis of partial agonism at NMDA receptors Nat. Neurosci. 12 9 2009 1114 1120
30. D.J. Laurie, and P.H. Seeburg Regional and developmental heterogeneity in splicing of the rat brain NMDAR1 mRNA J. Neurosci. 14 5 1994 3180 3194
31. S. Luvisetto, T. Fellin, M. Spagnolo, B. Hivert, P.F. Brust, M.M. Harpold, K.A. Stauderman, M.E. Williams, and D. Pietrobon Modal gating of human Ca(v)2.1 (P/Q-type) calcium channels: I. The slow and the fast gating modes and their modulation by beta subunits J. Gen. Physiol. 124 5 2004 445 461
32. N.V. Marrion Calcineurin regulates M channel modal gating in sympathetic neurons Neuron 16 1 1996 163 173
33. A. Meir, D.C. Bell, G.J. Stephens, K.M. Page, and A.C. Dolphin Calcium channel beta subunit promotes voltage-dependent modulation of alpha 1B by G beta gamma Biophys. J. 79 2 2000 731 746
34. H. Monyer, N. Burnashev, D.J. Laurie, B. Sakmann, and P.H. Seeburg Developmental and regional expression in the rat brain and functional properties of four NMDA receptors Neuron 12 3 1994 529 540
35. C. Mullner, D. Yakubovich, C.W. Dessauer, D. Platzer, and W. Schreibmayer Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation Biophys. J. 84 2 2003 1399 1409
36. D. Naranjo, and P. Brehm Modal shifts in acetylecholine receptor channel gating confer subunit-dependent desensitization Science 260 5115 1993 1811 1814
37. R. Ochi, and Y. Kawashima Modulation of slow gating process of calcium channels by isoprenaline in guinea-pig ventricular cells J. Physiol.-London 424 1990 187 204
38. 2+-dependent inactivation of 1-type calcium channels Neuron 22 3 1999 549 558
39. K. Poon, L.M. Nowak, and R.E. Oswald Characterizing single-channel behavior of GluA3 receptors Biophys. J. 99 5 2010 1437 1446
40. K. Poon, A.H. Ahmed, L.M. Nowak, and R.E. Oswald Mechanisms of modal activation of GluA3 receptors Mol. Pharmacol. 80 1 2011 49 59
41. G. Popescu, and A. Auerbach Modal gating of NMDA receptors and the shape of their synaptic response Nat. Neurosci. 6 5 2003 476 483
42. G. Popescu, A. Robert, J.R. Howe, and A. Auerbach Reaction mechanism determines NMDA receptor response to repetitive stimulation Nature 430 7001 2004 790 793
43. G.K. Popescu Modes of glutamate receptor gating J. Physiol.-London 590 1 2012 73 91
44. M.L. Prieto, and L.P. Wollmuth Gating modes in AMPA receptors J. Neurosci. 30 12 2010 4449 4459
45. 2+ J. Physiol.-London 562 2 2005 319 331
46. F. Qin, A. Auerbach, and F. Sachs Maximum likelihood estimation of aggregated Markov processes Proc. Royal Soc. B Biol. Sci. 264 1380 1997 375 383
47. C. Rosenmund, and G.L. Westbrook Calcium-induced actin depolymerization reduces NMDA channel activity Neuron 10 5 1993 805 814
48. B.K. Rycroft, and A.J. Gibb Direct effects of calmodulin on NMDA receptor single-channel gating in rat hippocampal granule cells J. Neurosci. 22 20 2002 8860 8868
49. B.K. Rycroft, and A.J. Gibb Regulation of single NMDA receptor channel activity by alpha-actinin and calmodulin in rat hippocampal granule cells J. Physiol.-London 557 3 2004 795 808
50. D. Singer-Lahat, N. Dascal, and I. Lotan Modal behavior of the Kv1.1 channel conferred by the Kv beta 1.1 subunit and its regulation by dephosphorylation of Kv1.1 Pflugers Archiv.-European J. Physiol. 439 1-2 1999 18 26
51. M.A. Smith, and M.L.J. Ashford Mode switching characterizes the activity of large conductance potassium channels recorded from rat cortical fused nerve terminals J. Physiol.-London 513 3 1998 733 747
52. D.G. Standaert, C.M. Testa, A. Young, and J.B. Penney Jr. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat J. Comp. Neurol. 343 1994 1 16
53. D.G. Standaert, G. Bernhard Landwehrmeyer, J.A. Kerner, J.B. Penney, and A.B. Young Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus Mol. Brain Res. 42 1 1996 89 102
54. D.G. Standaert, I.K. Friberg, G.B. Landwehrmeyer, A.B. Young, and J.B. Penney Expression of NMDA glutamate receptor subunit mRNAs in neurochemically identified projection and interneurons in the striatum of the rat Mol. Brain Res. 64 1 1999 11 23
55. S.F. Traynelis, L.P. Wollmuth, C.J. McBain, F.S. Menniti, K.M. Vance, K.K. Ogden, K.B. Hansen, H. Yuan, S.J. Myers, and R. Dingledine Glutamate receptor ion channels: structure, regulation, and function Pharmacol. Rev. 62 3 2010 405 496
56. K.M. Vance, N. Simorowski, S.F. Traynelis, and H. Furukawa Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors Nat. Commun. 2 2011 11
57. K.M. Vance, K.B. Hansen, and S.F. Traynelis GluN1 splice variant control of GluN1/GluN2D NMDA receptors J. Physiol.-London 590 16 2012 3857 3875
58. S. Vicini, J.F. Wang, J.H. Li, W.J. Zhu, Y.H. Wang, J.H. Luo, B.B. Wolfe, and D.R. Grayson Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors J. Neurophysiol. 79 2 1998 555 566
59. 2+ channel current in Xenopus oocytes J. Physiol.-London 517 3 1999 659 672
60. A. Wenzel, M. Villa, and H. Mohler Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain J. Neurochem. 66 3 1996 1240 1248
61. D.J.A. Wyllie, P. Behe, M. Nassar, R. Schoepfer, and D. Colquhoun Single-channel currents from recombinant NMDA NR1a/NR2D receptors expressed in Xenopus oocytes Proc. Royal Soc. B Biol. Sci. 263 1373 1996 1079 1086
62. D.J.A. Wyllie, P. Behe, and D. Colquhoun Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors J. Physiol. 510 1 1998 1 18
63. H. Yuan, K.B. Hansen, K.M. Vance, K.K. Ogden, and S.F. Traynelis Control of NMDA receptor function by the NR2 subunit amino-terminal domain J. Neurosci. 29 39 2009 12045 12058
64. D.T. Yue, P.H. Backx, and J.P. Imredy Calcium-sensitive inactivation in the gating of single calcium channels Science 250 4988 1990 1735 1738
65. S. Zhang, M.D. Ehlers, J.P. Bernhardt, C.T. Su, and R.L. Huganir Calmodulin mediates calcium-dependent inactivation of N-methyl-D-aspartate receptors Neuron 21 2 1998 443 453
66. W. Zhang, J.R. Howe, and G.K. Popescu Distinct gating modes determine the biphasic relaxation of NMDA receptor currents Nat. Neurosci. 11 12 2008 1373 1375