Chemical differentiation of Da-Cheng-Qi-Tang, a Chinese medicine formula, prepared by traditional and modern decoction methods using UPLC/Q-TOFMS-based metabolomics approach

Journal of Pharmaceutical and Biomedical Analysis

Volumn 83, Issue , 2013, Pages 34-42

  Wan, Jian Bo ^a   Bai, Xu ^b   Cai, Xiu Jiang ^a   Rao, Yi ^c   Wang, Yue Sheng ^c   Wang, Yi Tao ^a  

^a University of Macau   (Macao)

^b Waters Technologies Shanghai Ltd   (China)

^c JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Chemical consistency; Da Cheng Qi Tang; Metabolomics; Traditional decoction method; UPLC Q TOFMS

Indexed keywords

AURANTIIN; CHINESE DRUG; DA CHENG QI TANG; DIOSMETIN; LAXATIVE; MAGNOLOSIDE B; RHEIN; SENNOSIDE A; SENNOSIDE B; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL COMPOSITION; CHINESE MEDICINE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DECOCTION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG SCREENING; GASTROINTESTINAL DISEASE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METABOLOMICS; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY ELECTROSPRAY IONIZATION QUADRUPOLE TIME OF FLIGHT MASSSPECTROMETRY;

EID: 84878133557     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.04.019     Document Type: Article

References (28)

1. Zhang F.C., Chen M., Yan Y.D. Modern decoction method vs traditional decoction method. Zhong Guo Yao Fang 2008, 19:478-480. (Chinese).
2. Li S.L., Song J.Z., Qiao C.F., Zhou Y., Xu H.X. UPLC-PDA-TOFMS based chemical profiling approach to rapidly evaluate chemical consistency between traditional and dispensing granule decoctions of traditional medicine combinatorial formulae. J. Pharm. Biomed. Anal. 2010, 52:468-478.
3. Rochfort S. Metabolomics reviewed: a new "omics" platform technology for systems biology and implications for natural products research. J. Nat. Prod. 2005, 68:1813-1820.
4. Xiang Z., Wang X.Q., Cai X.J., Zeng S. Metabolomics study on quality control and discrimination of three curcuma species based on gas chromatograph-mass spectrometry. Phytochem. Anal. 2011, 22:411-418.
5. Wang X., Sun H., Zhang A., Sun W., Wang P., Wang Z. Potential role of metabolomics apporoaches in the area of traditional Chinese medicine: as pillars of the bridge between Chinese and Western medicine. J. Pharm. Biomed. Anal. 2011, 55:859-868.
6. Lee E.J., Shaykhutdinov R., Weljie A.M., Vogel H.J., Facchini P.J., Park S.U., Kim Y.K., Yang T.J. Quality assessment of ginseng by (1)H NMR metabolite fingerprinting and profiling analysis. J. Agric. Food Chem. 2009, 57:7513-7522.
7. Chan E.C., Yap S.L., Lau A.J., Leow P.C., Toh D.F., Koh H.L. Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng. Rapid Commun. Mass Spectrom. 2007, 21:519-528.
8. Toh D.F., New L.S., Koh H.L., Chan E.C. Ultra-high performance liquid chromatography/time-of-flight mass spectrometry (UHPLC/TOFMS) for time-dependent profiling of raw and steamed Panax notoginseng. J. Pharm. Biomed. Anal. 2010, 52:43-50.
9. Yang S.O., Shin Y.S., Hyun S.H., Cho S., Bang K.H., Lee D., Choi S.P., Choi H.K. NMR-based metabolic profiling and differentiation of ginseng roots according to cultivation ages. J. Pharm. Biomed. Anal. 2012, 58:19-26.
10. Kim N., Kim K., Lee D., Shin Y.S., Bang K.H., Cha S.W., Lee J.W., Choi H.K., Hwang B.Y. Nontargeted metabolomics approach for age differentiation and structure interpretation of age-dependent key constituents in hairy roots of Panax ginseng. J. Nat. Prod. 2012, 75:1777-1784.
11. Sun J., Chen P. Differentiation of Panax quinquefolius grown in the USA and China using LC/MS-based chromatographic fingerprinting and chemometric approaches. Anal. Bioanal. Chem. 2011, 399:1877-1889.
12. Tang W.F., Yu Q., Wan M.H., Qin F., Wang Y.G., Chen G.Y., Liang M.Z., Huang X. Simultaneous determination and pharmacokinetic studies of aloe emodin and chrysophanol in rats after oral administration of Da-Cheng-Qi decoction by high-performance liquid chromatography. Biomed. Chromatogr. 2007, 21:701-707.
13. Katakai M., Akamaru T., Tani T. An analysis of the frequency of formulations and crude drugs described in Shan-Han-Lun. Yakushigaku Zasshi 2002, 37:28-35.
14. Qi Q.H., Wang J., Liang G.G., Wu X.Z. Da-Cheng-Qi-Tang promotes the recovery of gastrointestinal motility after abdominal surgery in humans. Dig. Dis. Sci. 2007, 52:1562-1570.
15. Chen H., Li F., Jia J.G., Diao Y.P., Li Z.X., Sun J.B. Effects of traditional Chinese medicine on intestinal mucosal permeability in early phase of severe acute pancreatitis. Chin. Med. J. (Engl.) 2010, 123:1537-1542.
16. Wang R.Q., Chen J.Z., Ren G.Y. Intraperitoneal perfusion of compound injection of salvia miltiorrhiza with dachengqi decoction in treating adhesive intestinal obstruction. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994, 14:595-597. (Chinese).
17. Hu J. Modified DaChaiHu tang combined with DaChengQi tang decoction on 32 cases of acute cholecystitis treatment. Gan Su Zhong Yi Yao Za Zhi 2011, 24:25-26. (Chinese).
18. Xie R.F., Zhou X., Shi Z.N., Li Y.M., Li Z.C. Study on spectrum-effect relationship of Rhizoma Rhei, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus and their formula. J. Chromatogr. Sci. 2012, 10.1093/chromsci/bms172.
19. Yu Q., Xiang J., Tang W., Liang M., Qin Y., Nan F. Simultaneous determination of the 10 major components of Da-Cheng-Qi decoction in dog plasma by liquid chromatography tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2009, 877:2025-2031.
20. Zhang X.J., Huang L.L., Cai X.J., Li P., Wang Y.T., Wan J.B. Fatty acid variability in three medicinal herbs of Panax species. Chem. Cent. J. 2013, 7:12.
21. Su Z.H., Li S.Q., Zou G.A., Yu C.Y., Sun Y.G., Zhang H.W., Gu Y., Zou Z.M. Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats. J. Pharm. Biomed. Anal. 2011, 55:533-539.
22. Xu F., Liu Y., Zhang Z., Song R., Dong H., Tian Y. Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction. J. Pharm. Biomed. Anal. 2008, 47:586-595.
23. Xu F., Liu Y., Song R., Dong H., Zhang Z. Constituents of Da-Cheng-Qi decoction and its parent herbal medicines determined by LC-MS/MS. Nat. Prod. Commun. 2010, 5:789-794.
24. Zhao H.Y., Fan M.X., Wu X., Wang H.J., Yang J., Si N., Bian B.L. Chemical profiling of the chinese herb formula Xiao-Cheng-Qi decoction using liquid chromatography coupled with electrospray ionization mass spectrometry. J Chromatogr. Sci. 2013, 51:273-285.
25. Kisa K., Sasaki K., Yamauchi K., Kuwano S. Potentiating effect of sennoside C on purgative activity of sennoside A in mice. Planta Med. 1981, 42:302-303.
26. Takayama K., Tsutsumi H., Ishizu T., Okamura N. The influence of rhein 8-O-beta-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice. Biol. Pharm. Bull. 2012, 35:2204-2208.
27. Yamauchi K., Yagi T., Kuwano S. Suppression of the purgative action of rhein anthrone, the active metabolite of sennosides A and B, by calcium channel blockers, calmodulin antagonists and indomethacin. Pharmacology 1993, 47:22-31.
28. Yagi T., Miyawaki Y., Nishikawa T., Yamauchi K., Kuwano S. Involvement of prostaglandin E-like material in the purgative action of rhein anthrone, the intraluminal active metabolite of sennosides A and B in mice. J. Pharm. Pharmacol. 1988, 40:27-30.