Gelatin microparticles aggregates as three-dimensional scaffolding system in cartilage engineering

Journal of Materials Science: Materials in Medicine

Volumn 24, Issue 2, 2013, Pages 503-513

  Garcia Cruz D M ^a   Sardinha, V ^a,b   Escobar Ivirico, J L ^a   Mano, J F ^b   Gomez Ribelles J L ^a,c  

^a UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^b UNIVERSITY OF MINHO   (Portugal)

^c BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARTILAGE ENGINEERING; CHONDROCYTE PROLIFERATION; EXTRACELLULAR MATRICES; GELATIN MICROPARTICLES; GLYCOSAMINOGLYCANS; GROWTH FACTOR DELIVERY; SCAFFOLDING SYSTEMS; TRANSFORMING GROWTH FACTORS;

BODY FLUIDS; CELLS; CENTRIFUGATION; CYTOLOGY; ENZYME INHIBITION; MONOLAYERS; PELLETIZING; PROTEINS; THREE DIMENSIONAL; THREE DIMENSIONAL COMPUTER GRAPHICS; TISSUE;

SCAFFOLDS (BIOLOGY);

ACTIN; COLLAGEN TYPE 1; GELATIN; GLYCOSAMINOGLYCAN; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CARTILAGE CELL; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CYTOSKELETON; EXTRACELLULAR MATRIX; HUMAN; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CAPSULES; CARTILAGE; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; CHEMICAL PRECIPITATION; CHONDROCYTES; GELATIN; HUMANS; MICROSPHERES; PARTICLE SIZE; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1; WATER;

EID: 84878082495     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-012-4818-9     Document Type: Article

References (42)

1. Danisovic L, Varga I, Zamborsky R, Bohmer D. The tissue engineering of articular cartilage: cells, scaffolds and stimulating factors. Exp Biol Med. 2012;237(1):10-7.
2. Darling EM, Athanasiou KA. Rapid phenotypic changes in passaged articular chondrocyte subpopulations. J Orthop Res. 2005;23:425-32.
3. Oliveira MB, Mano JF. Polymer-based microparticles in tissue engineering and regenerative medicine. Biotechnol Prog. 2011;27(4):897-912.
4. Zhang R, Xue M, Yang J, Tan T. A novel injectable and in situ crosslinked hydrogel based on hyaluronic acid and α, β-polyaspartylhydrazide. J Appl Polym Sci. 2012;125(2):1116-26.
5. Hou Q, Chau DYS, Pratoomsoot C, Tighe PJ, Dua HS, Shakesheff KM, et al. In situ gelling hydrogels incorporating microparticles as drug delivery carriers for regenerative medicine. J Pharm Sci. 2008;97(9):3972-80.
6. Singh A, Suri S, Roy K. In situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA-DNA carrying microparticles to dendritic cells. Biomaterials. 2009;30(28):5187-200.
7. Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares RA, Granja PL. Injectable in situ crosslinkable RGD-modified alginate matrix for endothelial cells delivery. Biomaterials. 2011;32(31):7897-904.
8. Zheng Shu X, Liu Y, Palumbo FS, Luo Y, Prestwich GD. In situ crosslinkable hyaluronan hydrogels for tissue engineering. Biomaterials. 2004;25(7-8):1339-48.
9. Fan HB, Zhang CL, Li J, Bi L, Qin L, Wu H, et al. Gelatin microspheres containing TGF-beta 3 enhance the chondrogenesis of mesenchymal stem cells in modified pellet culture. Biomacromolecules. 2008;9(3):927-34.
10. Han YS, Wei YY, Wang SS, Song Y. Cartilage regeneration using adipose-derived stem cells and the controlled-released hybrid microspheres. Jt Bone Spine. 2010;77(1):27-31.
11. Park H, Temenoff JS, Tabata Y, Caplan AI, Mikos AG. Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials. 2007;28(21):3217-27.
12. Hu XH, Zhou J, Zhang N, Tan HP, Gao CY. Preparation and properties of an injectable scaffold of poly(lactic-co-glycolic acid) microparticles/chitosan hydrogel. J Mech Behav Biomed Mater. 2008;1(4):352-9.
13. Tan HP, Chu CR, Payne KA, Marra KG. Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering. Biomaterials. 2009;30(13):2499-506.
14. Malda J, Kreijveld E, Temenoff JS, van Blitterswijk CA, Riesle J. Expansion of human nasal chondrocytes on macroporous microcarriers enhances redifferentiation. Biomaterials. 2003;24(28):5153-61.
15. Glattauer V, White JF, Tsai WB, Tsai CC, Tebb TA, Danon SJ, et al. Preparation of resorbable collagen-based beads for direct use in tissue engineering and cell therapy applications. J Biomed Mater Res Part A. 2010;92A(4):1301-9.
16. Pettersson S, Wettero J, Tengvall P, Kratz G. Human articular chondrocytes on macroporous gelatin microcarriers form structurally stable constructs with blood-derived biological glues in vitro. J Tissue Eng Regen Med. 2009;3(6):450-60.
17. Fan HB, Hu YY, Qin L, Li XS, Wu H, Lv R. Porous gelatin-chondroitin- hyaluronate tri-copolymer scaffold containing microspheres loaded with TGF-beta 1 induces differentiation of mesenchymal stem cells in vivo for enhancing cartilage repair. J Biomed Mater Res Part A. 2006;77A(4):785-94.
18. García Cruz DM, Escobar Ivirico JL, Gomes MM, Gómez Ribelles JL, Sánchez, Reis RL, et al. Chitosan microparticles as injectable scaffolds for tissue engineering. J Tissue Eng Regen Med. 2008;2(6):378-80.
19. Leane MM, Nankervis R, Smith A, Illum L. Use of the ninhydrin assay to measure the release of chitosan from oral solid dosage forms. Int J Pharm. 2004;271(1-2):241-9.
20. Pérez Olmedilla M, Garcia-Giralt N, Pradas MM, Ruiz PB, Gómez Ribelles JL, Palou EC, et al. Response of human chondrocytes to a non-uniform distribution of hydrophilic domains on poly (ethyl acrylate-co-hydroxyethyl methacrylate) copolymers. Biomaterials. 2006;27(7):1003-12.
21. Alves da Silva ML, Crawford A, Mundy JM, Correlo VM, Sol P, Bhattacharya M, et al. Chitosan/polyester-based scaffolds for cartilage tissue engineering: Assessment of extracellular matrix formation. Acta Biomaterialia. 2010;6(3):1149-57.
22. Smith GD, Knutsen G, Richardson JB. A clinical review of cartilage repair techniques. J Bone Jt Surg Br Vol. 2005;87B(4):445-9.
23. Nehrer S, Domayer S, Dorotka R, Schatz K, Bindreiter U, Kotz R. Three-year clinical outcome after chondrocyte transplantation using a hyaluronan matrix for cartilage repair. Eur J Radiol. 2006;57(1):3-8.
24. Brittberg M, Peterson L, Sjogren-Jansson E, Tallheden T, Lindahl A. Articular cartilage engineering with autologous chondrocyte transplantation - A review of recent developments. J Bone Jt Surg Am Vol. 2003;85A:109-15.
25. Martinez-Diaz S, Garcia-Giralt N, Lebourg M, Gomez-Tejedor JA, Vila G, Caceres E, et al. In vivo evaluation of 3-dimensional polycaprolactone scaffolds for cartilage repair in rabbits. Am J Sports Med. 2010;38(3):509-19.
26. Pfander D, Rahmanzadeh R, Scheller EE. Presence and distribution of collagen II, collagen I, fibronectin, and tenascin in rabbit normal and osteoarthritic cartilage. J Rheumatol. 1999;26:386-94.
27. Huch K, Mordstein V, Stove J, Nerlich AG, Arnholdt H, Delling G, et al. Expression of collagen type I, II, X and Ki-67 in osteochondroma compared to human growth plate cartilage. Eur J Histochem. 2002;46(3):249-58.
28. Gohring AR, Lubke C, Andreas K, Haupl T, Sittinger M, Ringe J, et al. Tissue-engineered cartilage of porcine and human origin as in vitro test system in arthritis research. Biotechnol Prog. 2010;26(4):1116-25.
29. Tritz J, Rahouadj R, de Isla N, Charif N, Pinzano A, Mainard D, et al. Designing a three-dimensional alginate hydrogel by spraying method for cartilage tissue engineering. Soft Matter. 2010;6(20):5165-74.
30. Elisseeff J, McIntosh W, Fu K, Blunk T, Langer R. Controlled-release of IGF-I and TGF-β1 in a photopolymerizing hydrogel for cartilage tissue engineering. J Orthop Res. 2001;19(6):1098-104.
31. Park H, Temenoff JS, Holland TA, Tabata Y, Mikos AG. Delivery of TGF-beta 1 and chondrocytes via injectable, biodegradable hydrogels for cartilage tissue engineering applications. Biomaterials. 2005;26(34):7095-103. doi: 10.1016/j.biomaterials.2005.05.083.
32. Hwang NS, Varghese S, Zhang Z, Elisseeff J. Chondrogenic differentiation of human embryonic stem cell - Derived cells in arginine-glycine-aspartate - Modified hydrogels. Tissue Eng. 2006;12(9):2695-706.
33. Riley SL, Dutt S, de la Torre R, Chen AC, Sah RL, Ratcliffe A. Formulation of PEG-based hydrogels affects tissue-engineered cartilage construct characteristics. J Mater Sci Mater Med. 2001;12(10):983-90.
34. Chao P-HG, Yodmuang S, Wang X, Sun L, Kaplan DL, Vunjak-Novakovic G. Silk hydrogel for cartilage tissue engineering. J Biomed Mater Res B Appl Biomater. 2010;95B(1):84-90.
35. Nishi C, Nakajima N, Ikada Y. In vitro evaluation of cytotoxicity of diepoxy compounds used for biomaterial modification. J Biomed Mater Res. 1995;29(7):829-34.
36. Wang C, Lau TT, Loh WL, Su K, Wang D-A. Cytocompatibility study of a natural biomaterial crosslinker - Genipin with therapeutic model cells. J Biomed Mater Res B Appl Biomater. 2011;97B(1):58-65.
37. Lima EG, Tan AR, Tai T, Marra KG, DeFail A, Ateshian GA, et al. Genipin enhances the mechanical properties of tissue-engineered cartilage and protects against inflammatory degradation when used as a medium supplement. J Biomed Mater Res Part A. 2009;91A(3):692-700.
38. Solorio L, Zwolinski C, Lund AW, Farrell MJ, Stegemann JP. Gelatin microspheres crosslinked with genipin for local delivery of growth factors. J Tissue Eng Regen Med. 2010;4(7):514-23.
39. Lau TT, Wang C, Wang D-A. Cell delivery with genipin crosslinked gelatin microspheres in hydrogel/microcarrier composite. Compos Sci Technol. 2010;70(13):1909-14.
40. Solorio LD, Vieregge EL, Dhami CD, Dang PN, Alsberg E. Engineered cartilage via self-assembled hMSC sheets with incorporated biodegradable gelatin microspheres releasing transforming growth factor-b1. J Controlled Release. 2012;158(2):224-32.
41. Yamamoto M, Ikada Y, Tabata Y. Controlled release of growth factors based on biodegradation of gelatin hydrogel. J Biomater Sci Polym Ed. 2001;12(1):77-88.
42. Catelas I, Dwyer JF, Helgerson S. Controlled release of bioactive transforming growth factor beta-1 from fibrin gels in vitro. Tissue Eng Part C Method. 2008;14(2):119-28.