The Role of Cardiac Magnetic Resonance Imaging (MRI) in Acute Myocardial Infarction (AMI)

Heart Lung and Circulation

Volumn 22, Issue 4, 2013, Pages 243-255

  Ahmed, Nadeem ^a   Carrick, David ^a,b   Layland, Jamie ^a,b   Oldroyd, Keith G ^b   Berry, Colin ^a,b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b GOLDEN JUBILEE NATIONAL HOSPITAL   (United Kingdom)

Author keywords

Acute myocardial infarction (AMI); Infarct size (IS); Magnetic resonance imaging (MRI); Microvascular obstruction (MVO); Myocardial haemorrhage; Myocardial oedema

Indexed keywords

ACUTE HEART INFARCTION; BLEEDING; BLEEDING DISORDER; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL STUDY; CONTRAST ENHANCEMENT; COST EFFECTIVENESS ANALYSIS; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; FUNCTIONAL ASSESSMENT; HEART EDEMA; HEART FAILURE; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE INJURY; HEART MUSCLE NECROSIS; HUMAN; INTERMETHOD COMPARISON; MICROANGIOPATHY; MICROVASCULAR OBSTRUCTION; MYOCARDIAL PERFUSION IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROGNOSIS; REPERFUSION INJURY; REVIEW; RISK ASSESSMENT; THORAX PAIN;

EDEMA; HEART FAILURE; HEMORRHAGE; HUMANS; MAGNETIC RESONANCE IMAGING; MYOCARDIAL INFARCTION; NECROSIS; RISK FACTORS; STROKE VOLUME;

EID: 84878014828     PISSN: 14439506     EISSN: 14442892     Source Type: Journal    
DOI: 10.1016/j.hlc.2012.11.016     Document Type: Review

References (82)

1. Fox K.A., Steg P.G., Eagle K.A., Goodman S.G., Anderson F.A., Granger C.B., et al. Decline in rates of death and heart failure in acute coronary syndromes, 1999-2006. JAMA 2007, 297:1892-1900.
2. Fox K.A.A., Carruthers K.F., Dunbar D.R., Graham C., Manning J.R., De Raedt H., et al. Underestimated and under-recognized: the late consequences of acute coronary syndrome (GRACE UK-Belgian Study). Eur Heart J 2010, 32:2755-2764.
3. Reimer K.A., Lowe J.E., Rasmussen M.M., Jennings R.B. The wavefront phenomenon of ischemic cell death. Myocardial infarct size vs. duration of coronary occlusion in dogs. Circulation 1977, 56:788-794.
4. Ito H., Maruyama A., Iwakura K., Takiuchi S., Masuyama T., Hori M., et al. Clinical implications of the " no reflow" phenomenon. A predictor of complications and left ventricular remodelling in reperfused anterior wall myocardial infarction. Circulation 1996, 93:223-228.
5. Yellon D.M., Hausenloy D.J. Myocardial reperfusion injury. New Engl J Med 2007, 357:1121-1135.
6. Pfeffer M.A., Braunwald E. Ventricular remodelling after myocardial infarction: experimental observations and clinical implications. Circulation 1990, 81:1161-1172.
7. Araoz P., Glockner J., McGee K., Potter D.D., Valeti V.U., Stanley D.W., et al. 3 Tesla MR imaging provides improved contrast in first-pass myocardial perfusion imaging over a range of gadolinium doses. J Cardiovasc Magn Reson 2005, 7:559-564.
8. Pamboucas C., Schmitz S., Nihoyannopoulos P. Magnetic resonance imaging in the detection of myocardial viability: the role of delayed contrast hyperenhancement. Hellenic J Cardiol 2005, 46:108-116.
9. Gutberlet M., Noeske R., Schwinge K., Freyhardt P., Felix R., Niendorf T. Comprehensive cardiac magnetic resonance imaging at 3.0 Tesla: feasibility and implications for clinical applications. Invest Radiol 2006, 41:154-167.
10. Gharib A.M., Herzka D.A., Ustun A.O., Desai M.Y., Locklin J., Pettigrew R.I., et al. Coronary MR angiography at 3T during diastole and systole. J Magn Reson Imaging 2007, 26:921-926.
11. Ibrahim T., Bülow H.P., Hackl T., Hörnke M., Nekolla S.G., Breuer M., et al. Diagnostic value of contrast-enhanced magnetic resonance imaging and single- photon emission computed tomography for detection of myocardial necrosis early after acute myocardial infarction. J Am Coll Cardiol 2007, 49:208-216.
12. Kitagawa K., Sakuma H., Hirano T., Okamoto S., Makino K., Takeda K. Acute myocardial infarction: myocardial viability assessment in patients early thereafter comparison of contrast-enhanced MR imaging with resting (201) Tl SPECT: single photon emission computed tomography. Radiology 2003, 226:138-144.
13. Wagner A., Mahroldt H., Holly T.A., Elliott M.D., Regenfus M., Parker M., et al. Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study. Lancet 2003, 361:374-379.
14. Mahrholdt H., Klem I., Sechtem U. Cardiovascular MRI for detection of myocardial viability and ischaemia. Heart 2007, 93:122-129.
15. Wu Y.W., Tadamura E., Yamamuro M., Kanao S., Ozasa N., Toma M., et al. Myocardial viability by contrast-enhanced cardiovascular magnetic resonance in patients with coronary artery disease: comparison with gated single-photon emission tomography and FDG position emission tomography. Int J Cardiovasc Imaging 2007, 23(6):757-765.
16. Underwood S.R., Rees R.S., Savage P.E., Klipstein R.H., Firmin D.N., Fox K.M., et al. Assessment of regional left ventricular function by magnetic resonance. Br Heart J 1986, 56:334-340.
17. Grotheus F., Moon J.C.C., Bellenger N.G., Smith G.S., Klein H.U., Pennell D.J., et al. Interstudy reproducibility of right ventricular volumes, function and mass with cardiovascular magnetic resonance. Am Heart J 2004, 147:218-223.
18. Rehr R.B., Malloy C.R., Filipchuk N.G., Peshock R.M. Left ventricular volumes measured by MR imaging. Radiology 1985, 156:717-719.
19. Payne A.R., Casey M., McClure J., McGeoch R., Murphy A., Woodward R., et al. Bright blood T2 weighted MRI has higher diagnostic accuracy than dark blood STIR MRI for detection of acute myocardial infarction and for assessment of the ischemic area-at-risk and myocardial salvage. Circ Cardiovasc Imaging 2011, 4:210-219.
20. Kellman P., Larson A.C., Hsu L.-Y., Chung Y.-C., Simonetti O.P., McVeigh, et al. Motion-corrected free breathing delayed enhancement imaging of myocardial infarction. Magn Reson Med 2005, 53:194-200.
21. Aletras A.H., Tilak G.S., Natanzon A., Hsu L.Y., Gonzalez F.M., Hoyt R.F., et al. Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations. Circulation 2006, 113:1865-1870.
22. Wright J., Adriaenssens T., Dymarkowski S., Desmet W., Bogaert J. Quantification of myocardial area at risk with T2-weighted CMR: comparison with contrast-enhanced CMR and coronary angiography. J Am Coll Cardiol Img 2009, 2:825-831.
23. Carlsson M., Ubachs J.F., Hedstrom E., Heiberg E., Jovinge S., Arheden H. Myocardium at risk after acute infarction in humans on cardiac magnetic resonance: quantitative assessment during follow-up and validation with single-photon emission computed tomography. J AmColl Cardiol Img 2009, 2:569-576.
24. Raman S.V., Simonetti O.P., Winner M.W., Dickerson J.A., He X., Mazaferri E.L., et al. Cardiac magnetic resonance with edema imaging identifies myocardium at risk and predicts worse outcome in patients with non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol 2010, 55:2480-2488.
25. Eitel I., Desch S., Fuernau G., Hildebrand L., Gutberlet M., Schuler G., et al. Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction. J Am Coll Cardiol 2010, 55:2470-2479.
26. Eitel I., Desch S., De Waha S., Fuernau G., Gutberlet M., Schuler G., et al. Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction. Heart 2011, 97:2038-2045.
27. Abdel-Aty H., Cocker M., Meek C., Tyberg J.V., Friedrich M.G. Edema as a very early marker for acute myocardial ischemia: a cardiovascular magnetic resonance study. J Am Coll Cardiol 2009, 53:1194-1201.
28. Abdel-Aty H., Zagrosek A., Schulz-Menger J., Taylor A.J., Messroghli D., Kumar A., et al. Delayed enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction. Circulation 2004, 109:2411-2416.
29. Ugander M., Bagi P.S., Oki A.J., Chen B., Hsu L.Y., Aletras A.H., et al. Myocardial edema as detected by precontrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction. J Am Coll Cardiol Img 2012, 5:596-603.
30. Verhaert D., Thavendiranathan P., Giri S., Mihai G., Rajagopalan S., Simonetti O.P., et al. Direct T2 quantification of myocardial edema in acute ischemic injury. JACC Cardiovasc Imaging 2011, 4:269-278.
31. Cury R.C., Shash K., Nagurney J.T., Rosito G., Shapiro M.D., Nomura C.H., et al. Cardiac magnetic resonance with T2-weighted imaging improves detection of patients with acute coronary syndrome in the emergency department. Circulation 2008, 118:837-844.
32. Basso C., Rizzo S., Thiene G. The metamorphosis of myocardial infarction following coronary recanalization. Cardiovasc Pathol 2010, 19:22-28.
33. Ganame J., Messalli G., Dymarkowski S., Rademakers F.E., Desmet W., Van de W.F., et al. Impact of myocardial haemorrhage on left ventricular function and remodelling in patients with reperfused acute myocardial infarction. Eur Heart J 2009, 30:1440-1449.
34. Mather A.N., Fairbairn T.A., Ball S.G., Greenwood J.P., Plein S. Reperfusion haemorrhage as determined by cardiovascular MRI is a predictor of adverse left ventricular remodelling and markers of late arrhythmic risk. Heart 2011, 97:453-459.
35. O'Regan D.P., Ahmed R., Karunanithy N., Neuwirth C., Tan Y., Durighel G., et al. Reperfusion haemorrhage following acute myocardial infarction: assessment with T2 mapping and effect on measuring the area at risk. Radiology 2009, 250:916-922.
36. Heinrichs U., Utting J.F., Frauenrath T., Hezel F., Krombach G.A., Hodenius M.A.J., et al. Myocardial T2 mapping free of distortion using susceptibility-weighted fast spin-echo imaging: a feasibility study at 1.5 T and 3.0 T. Magn Reson Med 2009, 62:822-828.
37. Simonetti O.P., Kim R.J., Fieno D.S., Hillenbrand H.B., Wu E., Bundy J.M., et al. An improved MR imaging technique for the visualization of myocardial infarction. Radiology 2001, 218:215-223.
38. Kim R.J., Fieno D.S., Parrish T.B., Harris K., Chen E.L., Simonetti O., et al. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation 1999, 100:1992-2002.
39. Judd R.M., Lugo-Olivieri C.H., Arai M., Kondo T., Croisille P., Lima J.A., et al. Physiological basis of myocardial contrast enhancement in fast magnetic resonance images of a 2-day-old reperfused canine infarcts. Circulation 1995, 92:1902-1910.
40. Saeed M., Lund G., Wendland M.F., Bremerich J., Weinmann H., Higgins C.B. Magnetic resonance characterization of the peri-infarction zone of reperfused myocardial infarction with necrosis-specific and extracellular nonspecific contrast media. Circulation 2001, 103:871-876.
41. Hombach V., Grebe O., Merkle N., Waldenmaier S., Höher M., Kochs M., et al. Sequelae of acute myocardial infarction regarding cardiac structure and function and their prognostic significance as assessed by magnetic resonance imaging. Eur Heart J 2005, 26:549-557.
42. Ingkanisorn W.P., Rhoads K.L., Aletras A.H., Kellman P., Arai A.E. Gadolinium delayed enhancement cardiovascular magnetic resonance correlates with clinical measures of myocardial infarction. J Am Coll Cardiol 2004, 43:2253-2259.
43. Kim R.J., Choi K.M., Judd R.M. Assessment of myocardial viability by contrast enhancement. Cardiovascular MRI and MRA 2003, 209-236. Lippincott-Williams &Wilkins, Philadelphia, PA. C.B. Higgins, A.D. Roos (Eds.).
44. Kwong R.Y., Farzaneh-Far A. Measuring myocardial scar by CMR. JACC Cardiovasc Imaging 2011, 4:157-160.
45. Wu E., Judd R.M., Vargas J.D., Klocke F.J., Bonow R.O., Kim R.J. Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. Lancet 2001, 357:21-28.
46. Klein C., Nekolla S.G., Bengel F.M., Momose M., Sammer A., Haas F., et al. Assessment of myocardial viability with contrast-enhanced magnetic resonance imaging: comparison with positron emission tomography. Circulation 2002, 105:162-167.
47. Ibrahim T., Nekolla S.G., Hornke M., Bulow H.P., Dirschinger J., Schomig A., et al. Quantitative measurement of infarct size by contrast-enhanced magnetic resonance imaging early after acute myocardial infarction: comparison with single-photon emission tomography usingTc99m-sestamibi. J Am Coll Cardiol 2005, 45:544-552.
48. Kim R.J., Wu E., Rafael A., Chen E.L., Parker M.A., Simonetti O., et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. New Engl J Med 2000, 343:1445-1453.
49. Fieno D.S., Kim R.J., Chen E.L., Lomasney J.W., Klocke F.J., Judd R.M. Contrast-enhanced magnetic resonance imaging of myocardium at risk: distinction between reversible and irreversible injury throughout infarct healing. J Am Coll Cardiol 2000, 36:1985-1991.
50. Bondarenko O., Beek A.M., Hofman M.B., Kühl H.P., Twisk J.W., van Dockum W.G., et al. Standardizing the definition of hyperenhancement in the quantitative assessment of infarct size and myocardial viability using delayed contrast-enhanced CMR. J Cardiovasc Magn Reson 2005, 7:481-485.
51. Choi K.M., Kim R.J., Gubernikoff G., Vargas J.D., Parker M., Judd R.M. Transmural extent of acute myocardial infarction predicts long-term improvement in contractile function. Circulation 2001, 104:1101-1107.
52. Mahrholdt H., Wagner A., Parker M., Regenfus M., Fieno D.S., Bonow R.O., et al. Relationship of contractile function to transmural extent of infarction in patients with chronic coronary artery disease. J Am Coll Cardiol 2003, 42:505-512.
53. Gerber B.L., Garot J., Bluemke D.A., Wu K.C., Lima J.A. Accuracy of contrast-enhanced magnetic resonance imaging in predicting improvement of regional myocardial function in patients after acute myocardial infarction. Circulation 2002, 106:1083-1089.
54. Srichai M.B., Junor C., Rodriguez L.L., Stillman A.E., Grimm R.A., Lieber M.L., et al. Clinical, imaging, and pathological characteristics of left ventricular thrombus: a comparison of contrast-enhanced magnetic resonance imaging, transthoracic echocardiography, and transesophageal echocardiography with surgical or pathological validation. Am Heart J 2006, 152(1):75-84.
55. Weinsaft J.W., Kim R.J., Ross M., Krauser D., Manoushagian S., LaBounty T.M., et al. Contrast-enhanced anatomic imaging as compared to contrast-enhanced tissue characterization for detection of left ventricular thrombus. JACC Cardiovasc Imaging 2009, 2(8):969-979.
56. Wu K.C., Kim R.J., Bluemke D.A., Rochitte C.E., Zerhouni E.A., Becker L.C., et al. Quantification and time course of microvascular obstruction by contrast-enhanced echocardiography and magnetic resonance imaging following acute myocardial infarction and reperfusion. J Am Coll Cardiol 1998, 32:1756-1764.
57. Tarantini G., Razzolini R., Cacciavillani L., Bilato C., Sarais C., Corbetti F., et al. Influence of transmurality, infarct size, and severe microvascular obstruction on left ventricular remodelling and function after primary coronary angioplasty. Am J Cardiol 2006, 98:1033-1040.
58. Wu K.C., Zerhouni E.A., Judd R.M., Lugo-Olivieri C.H., Barouch L.A., Schulman S.P., et al. Prognostic significance of microvascular obstruction by magnetic resonance imaging in patients with acute myocardial infarction. Circulation 1998, 97:765-772.
59. Ochiai K., Shimada T., Murakami Y., Ishibashi Y., Sano K., Kitamura J. Haemorrhagic myocardial infarction after coronary reperfusion detected in vivo by magnetic resonance imaging in humans: prevalence and clinical implications. J Cardiovasc Magn Resonan 1999, 1:247-256.
60. Hamon M., Fau G., Née G., Ehtisham J., Morello R., Hamon M. Meta-analysis of the diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of coronary artery disease. J Cardiovasc Magn Reson 2010, 12:29.
61. Lund G.K., Stork A., Saeed M., Bansmann M.P., Gerken J.H., Müller V., et al. Acute myocardial infarction: evaluation with first-pass enhancement and delayed enhancement MR imaging compared with 201Tl SPECT imaging. Radiology 2004, 232:49-57.
62. Wendland M.F., Saeed M., Masui T., Derugin N., Moseley M.E., Higgins C.B. Echoplanar MR imaging of normal and ischemic myocardium with gadodiamide injection. Radiology 1993, 186:535-542.
63. Kwong R.Y., Schussheim A.E., Rekhraj S., Aletras A.H., Geller N., Davis J., et al. Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging. Circulation 2003, 107:531-537.
64. Atkinson D.J., Burstein D., Edelman R.R. First pass cardiac perfusion: evaluation with ultrafast MR imaging. Radiology 1990, 174:757-762.
65. Yu K.K., Saeed M., Wendland M.F., Dae M.W., Velasquez-Rocha S., Derugin N., et al. Comparison of T1-enhancing and magnetic susceptibility magnetic resonance contrast agents for demarcation of the jeopardy area in experimental myocardial infarction. Invest Radiol 1993, 28:1015-1023.
66. Van Dijk P. Direct cardiac NMR imaging of heart wall and blood flow velocity. J Comput Assist Tomogr 1984, 8:588-593.
67. Chatzimavroudis G.P., Oshinski J.N., Franch R.H., Walker P.G., Yoganathan A.P., Pettigrew R.I. Evaluation of the precision of magnetic resonance phase velocity mapping for blood flow measurements. J Cardiovasc Magn Reson Imaging 2001, 3:27-34.
68. Eichenberger A.C., Jenni R., von Schulthess G.K. Aortic valve pressure gradients in patients with aortic valve stenosis: quantification with velocity-encoded cine MR imaging. AJR 1993, 160:971-977.
69. Dulce M.C., Mostbeck G.H., O'Sullivan M., Cheitlin M., Caputo G.R., Higgins C.B. Severity of aortic regurgitation: an interstudy reproducibility of measurements with velocity encoded cine MRI. Radiology 1992, 185:235-240.
70. Chan K.M., Wage R., Symmonds K., Rahman-Haley S., Mohiaddin R.H., Firmin D.N., et al. Towards comprehensive assessment of mitral regurgitation using cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2008, 22(10):61.
71. Inoue Y., Yang X., Nagao M., Higashino H., Hosokawa K., Kido T., et al. Peri-infarct dysfunction in post-myocardial infarction: assessment of 3-T tagged and late enhancement MRI. Eur Radiol 2010, 20:1139-1148.
72. Wong D.T., Weightman M.J., Baumert M., Tayeb H., Richardson J.D., Puri R. Electromechanical characteristics of myocardial infarction border zones and ventricular arrhythmic risk: novel insights from grid-tagged cardiac magnetic resonance imaging. Eur Radiol 2012, 22:1651-1658.
73. Petrank Y.F., Dong S.J., Tyberg J., Sideman S., Beyar R. Regional differences in shape and load in normal and diseased hearts studied by three dimensional tagged magnetic resonance imaging. Int J Card Imaging 1999, 15:309-321.
74. Lorenz C.H., Pastorek J.S., Bundy J.M. Delineation of normal human left ventricular twist throughout systole by tagged cine magnetic resonance imaging. J Cardiovasc Magn Reson 2000, 2:97-108.
75. de Waha S., Fuernau G., Eitel I., Lurz P., Desch S., Schuler G., et al. Measuring treatment effects in clinical trials using cardiac MRI. Curr Cardiovasc Imaging Rep 2011, 4:98-107.
76. Quinones M.A. Risk stratification survival after myocardial infarction. N Engl J Med 1983, 309:331-336.
77. Eitel I., Desch S., de Waha S., Fuernau G., Gutberlet M., Schuler G., et al. Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction. Heart 2011, 97(24):2038-2045.
78. Miller C.D., Hwang W., Case D., Hoekstra J.W., Lefebvre C., Blumstein H., et al. Stress cardiac magnetic resonance imaging with observation unit care reduces cost for patients with emergent chest pain: a randomized trial. Ann Emerg Med 2010, 56:209e2-219e2.
79. Hombach V., Merkle N., Kestler H.A., Torzewski J., Kochs M., Marx N., et al. Characterization of patients with acute chest pain using cardiac magnetic resonance imaging. Clin Res Cardiol 2008, 97:760-777.
80. Stensaeth K.H., Hoffmann P., Fossum E., Mangschau A., Sandvik L., Klow N.E. Clinical characteristics and role of early cardiac magnetic resonance imaging in patients with suspected ST-elevation myocardial infarction and normal coronary arteries. Int J Cardiovasc Imaging (formerly Cardiac Imaging) 2010, 1-11.
81. Karolle B.L., Carlson R.E., Aisen A.M., Buda A.J. Transmural distribution of myocardial edema by NMR relaxometry following myocardial ischemia and reperfusion. Am Heart J 1991, 122:655-664. 60.
82. Friedrich M.G., Sechtem U., Schulz-Menger J., Holmvang G., Alakija P., Cooper L.T., et al. Cardiovascular magnetic resonance in myocarditis: a JACC White Paper. J Am Coll Cardiol 2009, 53:1475-1487.