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Volumn 154, Issue 6, 2013, Pages 845-855

Adaptations in responsiveness of brainstem pain-modulating neurons in acute compared with chronic inflammation

Author keywords

Complete Freund's adjuvant; Descending control; OFF cells; Rostral ventromedial medulla

Indexed keywords

FREUND ADJUVANT;

EID: 84878012554     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.02.019     Document Type: Article
Times cited : (40)

References (59)
  • 1
    • 0033555793 scopus 로고    scopus 로고
    • Peripheral inflammation facilitates Aβ fiber-mediated synaptic input to the substantia gelatinosa of the adult rat spinal cord
    • H. Baba, T.P. Doubell, and C.J. Woolf Peripheral inflammation facilitates Aβ fiber-mediated synaptic input to the substantia gelatinosa of the adult rat spinal cord J Neurosci 19 1999 859 867
    • (1999) J Neurosci , vol.19 , pp. 859-867
    • Baba, H.1    Doubell, T.P.2    Woolf, C.J.3
  • 2
    • 0022620182 scopus 로고
    • Putative pain modulating neurons in the rostral ventral medulla: Reflex-related activity predicts effects of morphine
    • N.M. Barbaro, M.M. Heinricher, and H.L. Fields Putative pain modulating neurons in the rostral ventral medulla: reflex-related activity predicts effects of morphine Brain Res 366 1986 203 210
    • (1986) Brain Res , vol.366 , pp. 203-210
    • Barbaro, N.M.1    Heinricher, M.M.2    Fields, H.L.3
  • 3
    • 0025054545 scopus 로고
    • Hyperalgesia during naloxone-precipitated withdrawal from morphine is associated with increased on-cell activity in the rostral ventromedial medulla
    • J.B. Bederson, H.L. Fields, and N.M. Barbaro Hyperalgesia during naloxone-precipitated withdrawal from morphine is associated with increased on-cell activity in the rostral ventromedial medulla Somatosens Mot Res 7 1990 185 203
    • (1990) Somatosens Mot Res , vol.7 , pp. 185-203
    • Bederson, J.B.1    Fields, H.L.2    Barbaro, N.M.3
  • 4
    • 84856982459 scopus 로고    scopus 로고
    • Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors
    • T.S. Brink, C. Pacharinsak, S.G. Khasabov, A.J. Beitz, and D.A. Simone Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors J Neurophysiol 107 2012 1210 1221
    • (2012) J Neurophysiol , vol.107 , pp. 1210-1221
    • Brink, T.S.1    Pacharinsak, C.2    Khasabov, S.G.3    Beitz, A.J.4    Simone, D.A.5
  • 5
    • 36849060297 scopus 로고    scopus 로고
    • Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury
    • J.D. Carlson, J.J. Maire, M.E. Martenson, and M.M. Heinricher Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury J Neurosci 27 2007 13222 13231
    • (2007) J Neurosci , vol.27 , pp. 13222-13231
    • Carlson, J.D.1    Maire, J.J.2    Martenson, M.E.3    Heinricher, M.M.4
  • 6
    • 79851507471 scopus 로고    scopus 로고
    • A reassessment of stress-induced "analgesia" in the rat using an unbiased method
    • P. Carrive, M. Churyukanov, and D. Le Bars A reassessment of stress-induced "analgesia" in the rat using an unbiased method PAIN® 152 2011 676 686
    • (2011) PAIN® , vol.152 , pp. 676-686
    • Carrive, P.1    Churyukanov, M.2    Le Bars, D.3
  • 7
    • 84864059368 scopus 로고    scopus 로고
    • A novel, non-invasive method of respiratory monitoring for use with stereotactic procedures
    • D.R. Cleary, R.S. Phillips, M. Wallisch, and M.M. Heinricher A novel, non-invasive method of respiratory monitoring for use with stereotactic procedures J Neurosci Methods 209 2012 337 343
    • (2012) J Neurosci Methods , vol.209 , pp. 337-343
    • Cleary, D.R.1    Phillips, R.S.2    Wallisch, M.3    Heinricher, M.M.4
  • 8
    • 0032188778 scopus 로고    scopus 로고
    • Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia
    • S.V. Coutinho, M.O. Urban, and G.F. Gebhart Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia PAIN® 78 1998 59 69
    • (1998) PAIN® , vol.78 , pp. 59-69
    • Coutinho, S.V.1    Urban, M.O.2    Gebhart, G.F.3
  • 9
    • 77949918672 scopus 로고    scopus 로고
    • Activation of NMDA receptors in the brainstem, rostral ventromedial medulla, and nucleus reticularis gigantocellularis mediates mechanical hyperalgesia produced by repeated intramuscular injections of acidic saline in rats
    • L.F. Da Silva, J.M. DeSantana, and K.A. Sluka Activation of NMDA receptors in the brainstem, rostral ventromedial medulla, and nucleus reticularis gigantocellularis mediates mechanical hyperalgesia produced by repeated intramuscular injections of acidic saline in rats J Pain 11 2010 378 387
    • (2010) J Pain , vol.11 , pp. 378-387
    • Da Silva, L.F.1    Desantana, J.M.2    Sluka, K.A.3
  • 10
    • 83155164319 scopus 로고    scopus 로고
    • Changes in expression of NMDA-NR1 receptor subunits in the rostral ventromedial medulla modulate pain behaviors
    • L.F. Da Silva, R.Y. Walder, B.L. Davidson, S.P. Wilson, and K.A. Sluka Changes in expression of NMDA-NR1 receptor subunits in the rostral ventromedial medulla modulate pain behaviors PAIN® 151 2010 155 161
    • (2010) PAIN® , vol.151 , pp. 155-161
    • Da Silva, L.F.1    Walder, R.Y.2    Davidson, B.L.3    Wilson, S.P.4    Sluka, K.A.5
  • 12
    • 0017818987 scopus 로고
    • The need to control skin temperature when using radiant heat in tests of analgesia
    • A.W. Duggan, B.T. Griersmith, P.M. Headley, and J.B. Maher The need to control skin temperature when using radiant heat in tests of analgesia Exp Neurol 61 1978 471 478
    • (1978) Exp Neurol , vol.61 , pp. 471-478
    • Duggan, A.W.1    Griersmith, B.T.2    Headley, P.M.3    Maher, J.B.4
  • 13
    • 3042789578 scopus 로고    scopus 로고
    • State-dependent opioid control of pain
    • H. Fields State-dependent opioid control of pain Nat Rev Neurosci 5 2004 565 575
    • (2004) Nat Rev Neurosci , vol.5 , pp. 565-575
    • Fields, H.1
  • 14
    • 33645392052 scopus 로고    scopus 로고
    • Central nervous system mechanisms of pain modulation
    • S. McMahon, M. Koltzenburg, 5th ed. Elsevier London
    • H.L. Fields, A.I. Basbaum, and M.M. Heinricher Central nervous system mechanisms of pain modulation S. McMahon, M. Koltzenburg, Wall and Melzack's textbook of pain 5th ed. 2006 Elsevier London 125 142
    • (2006) Wall and Melzack's Textbook of Pain , pp. 125-142
    • Fields, H.L.1    Basbaum, A.I.2    Heinricher, M.M.3
  • 16
    • 3242746754 scopus 로고    scopus 로고
    • Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats
    • Y. Guan, W. Guo, M.T. Robbins, R. Dubner, and K. Ren Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats Neurosci Lett 366 2004 201 205
    • (2004) Neurosci Lett , vol.366 , pp. 201-205
    • Guan, Y.1    Guo, W.2    Robbins, M.T.3    Dubner, R.4    Ren, K.5
  • 17
    • 0038161060 scopus 로고    scopus 로고
    • Inflammation-induced upregulation of AMPA receptor subunit expression in brain stem pain modulatory circuitry
    • Y. Guan, W. Guo, S.-P. Zou, R. Dubner, and K. Ren Inflammation-induced upregulation of AMPA receptor subunit expression in brain stem pain modulatory circuitry PAIN® 104 2003 401 413
    • (2003) PAIN® , vol.104 , pp. 401-413
    • Guan, Y.1    Guo, W.2    Zou, S.-P.3    Dubner, R.4    Ren, K.5
  • 18
    • 0036156527 scopus 로고    scopus 로고
    • Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation
    • Y. Guan, R. Terayama, R. Dubner, and K. Ren Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation J Pharmacol Exp Ther 300 2002 513 520
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 513-520
    • Guan, Y.1    Terayama, R.2    Dubner, R.3    Ren, K.4
  • 19
    • 30644477580 scopus 로고    scopus 로고
    • Supraspinal brain-derived neurotrophic factor signaling: A novel mechanism for descending pain facilitation
    • W. Guo, M.T. Robbins, F. Wei, S. Zou, R. Dubner, and K. Ren Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation J Neurosci 26 2006 126 137
    • (2006) J Neurosci , vol.26 , pp. 126-137
    • Guo, W.1    Robbins, M.T.2    Wei, F.3    Zou, S.4    Dubner, R.5    Ren, K.6
  • 20
    • 72749113618 scopus 로고    scopus 로고
    • Effects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociception
    • M.V. Hamity, S.R. White, and D.L. Hammond Effects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociception Neuroscience 165 2010 902 913
    • (2010) Neuroscience , vol.165 , pp. 902-913
    • Hamity, M.V.1    White, S.R.2    Hammond, D.L.3
  • 21
    • 0033968982 scopus 로고    scopus 로고
    • Delta opioid receptor mediated actions in the rostral ventromedial medulla on tail flick latency and nociceptive modulatory neurons
    • I. Harasawa, H.L. Fields, and I.D. Meng Delta opioid receptor mediated actions in the rostral ventromedial medulla on tail flick latency and nociceptive modulatory neurons PAIN® 85 2000 255 262
    • (2000) PAIN® , vol.85 , pp. 255-262
    • Harasawa, I.1    Fields, H.L.2    Meng, I.D.3
  • 22
    • 3242683392 scopus 로고    scopus 로고
    • 2 in the midbrain periaqueductal gray produces hyperalgesia and activates pain-modulating circuitry in the rostral ventromedial medulla
    • 2 in the midbrain periaqueductal gray produces hyperalgesia and activates pain-modulating circuitry in the rostral ventromedial medulla PAIN® 110 2004 419 426
    • (2004) PAIN® , vol.110 , pp. 419-426
    • Heinricher, M.M.1    Martenson, M.E.2    Neubert, M.J.3
  • 23
    • 0026576472 scopus 로고
    • Direct and indirect actions of morphine on medullary neurons that modulate nociception
    • M.M. Heinricher, M.M. Morgan, and H.L. Fields Direct and indirect actions of morphine on medullary neurons that modulate nociception Neuroscience 48 1992 533 543
    • (1992) Neuroscience , vol.48 , pp. 533-543
    • Heinricher, M.M.1    Morgan, M.M.2    Fields, H.L.3
  • 24
    • 0027968011 scopus 로고
    • Disinhibition of off-cells and antinociception produced by an opioid action within the rostral ventromedial medulla
    • M.M. Heinricher, M.M. Morgan, V. Tortorici, and H.L. Fields Disinhibition of off-cells and antinociception produced by an opioid action within the rostral ventromedial medulla Neuroscience 63 1994 279 288
    • (1994) Neuroscience , vol.63 , pp. 279-288
    • Heinricher, M.M.1    Morgan, M.M.2    Tortorici, V.3    Fields, H.L.4
  • 25
    • 4444328321 scopus 로고    scopus 로고
    • Neural basis for the hyperalgesic action of cholecystokinin in the rostral ventromedial medulla
    • M.M. Heinricher, and M.J. Neubert Neural basis for the hyperalgesic action of cholecystokinin in the rostral ventromedial medulla J Neurophysiol 92 2004 1982 1989
    • (2004) J Neurophysiol , vol.92 , pp. 1982-1989
    • Heinricher, M.M.1    Neubert, M.J.2
  • 26
    • 63449092750 scopus 로고    scopus 로고
    • Descending control of nociception: Specificity, recruitment and plasticity
    • M.M. Heinricher, I. Tavares, J.L. Leith, and B.M. Lumb Descending control of nociception: specificity, recruitment and plasticity Brain Res Rev 60 2009 214 225
    • (2009) Brain Res Rev , vol.60 , pp. 214-225
    • Heinricher, M.M.1    Tavares, I.2    Leith, J.L.3    Lumb, B.M.4
  • 27
    • 0027277120 scopus 로고
    • The tail-flick and formalin tests in rodents: Changes in skin temperature as a confounding factor
    • K. Hole, and A. Tjølsen The tail-flick and formalin tests in rodents: changes in skin temperature as a confounding factor PAIN® 53 1993 247 254
    • (1993) PAIN® , vol.53 , pp. 247-254
    • Hole, K.1    Tjølsen, A.2
  • 28
    • 0034143366 scopus 로고    scopus 로고
    • The analgesic effects of supraspinal μ and δ opioid receptor agonists are potentiated during persistent inflammation
    • R.W. Hurley, and D.L. Hammond The analgesic effects of supraspinal μ and δ opioid receptor agonists are potentiated during persistent inflammation J Neurosci 20 2000 1249 1259
    • (2000) J Neurosci , vol.20 , pp. 1249-1259
    • Hurley, R.W.1    Hammond, D.L.2
  • 29
    • 2142817905 scopus 로고    scopus 로고
    • Isoflurane differentially modulates medullary on and off neurons while suppressing hind-limb motor withdrawals
    • S.L. Jinks, E. Carstens, and J.F. Antognini Isoflurane differentially modulates medullary ON and OFF neurons while suppressing hind-limb motor withdrawals Anesthesiology 100 2004 1224 1234
    • (2004) Anesthesiology , vol.100 , pp. 1224-1234
    • Jinks, S.L.1    Carstens, E.2    Antognini, J.F.3
  • 30
    • 33644803655 scopus 로고    scopus 로고
    • Role for medullary pain facilitating neurons in secondary thermal hyperalgesia
    • W. Kincaid, M.J. Neubert, M. Xu, C.J. Kim, and M.M. Heinricher Role for medullary pain facilitating neurons in secondary thermal hyperalgesia J Neurophysiol 95 2006 33 41
    • (2006) J Neurophysiol , vol.95 , pp. 33-41
    • Kincaid, W.1    Neubert, M.J.2    Xu, M.3    Kim, C.J.4    Heinricher, M.M.5
  • 31
    • 78650169017 scopus 로고    scopus 로고
    • Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla
    • S.C. LaGraize, W. Guo, K. Yang, F. Wei, K. Ren, and R. Dubner Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla Neuroscience 171 2010 1341 1356
    • (2010) Neuroscience , vol.171 , pp. 1341-1356
    • Lagraize, S.C.1    Guo, W.2    Yang, K.3    Wei, F.4    Ren, K.5    Dubner, R.6
  • 32
    • 61849158239 scopus 로고    scopus 로고
    • A possible neural basis for stress-induced hyperalgesia
    • M.E. Martenson, J.S. Cetas, and M.M. Heinricher A possible neural basis for stress-induced hyperalgesia PAIN® 142 2009 236 244
    • (2009) PAIN® , vol.142 , pp. 236-244
    • Martenson, M.E.1    Cetas, J.S.2    Heinricher, M.M.3
  • 33
    • 7744237079 scopus 로고    scopus 로고
    • A reliable method for the preferential activation of c- or a-fibre heat nociceptors
    • S. McMullan, D.A.A. Simpson, and B.M. Lumb A reliable method for the preferential activation of c- or a-fibre heat nociceptors J Neurosci Methods 138 2004 133 139
    • (2004) J Neurosci Methods , vol.138 , pp. 133-139
    • McMullan, S.1    Simpson, D.A.A.2    Lumb, B.M.3
  • 34
    • 0036092615 scopus 로고    scopus 로고
    • Changes in gene expression and neuronal phenotype in brain stem pain modulatory circuitry after inflammation
    • K. Miki, Q.Q. Zhou, W. Guo, Y. Guan, R. Terayama, R. Dubner, and K. Ren Changes in gene expression and neuronal phenotype in brain stem pain modulatory circuitry after inflammation J Neurophysiol 87 2002 750 760
    • (2002) J Neurophysiol , vol.87 , pp. 750-760
    • Miki, K.1    Zhou, Q.Q.2    Guo, W.3    Guan, Y.4    Terayama, R.5    Dubner, R.6    Ren, K.7
  • 35
    • 0027930029 scopus 로고
    • Are ventromedial medulla neuronal properties modified by chronic peripheral inflammation? A single-unit study in the awake, freely moving polyarthritic rat
    • J. Montagne-Clavel, and J.L. Oliveras Are ventromedial medulla neuronal properties modified by chronic peripheral inflammation? A single-unit study in the awake, freely moving polyarthritic rat Brain Res 657 1994 92 104
    • (1994) Brain Res , vol.657 , pp. 92-104
    • Montagne-Clavel, J.1    Oliveras, J.L.2
  • 38
    • 0035958715 scopus 로고    scopus 로고
    • Response properties of neurons in the rostroventromedial medulla of neuropathic rats: Attempted modulation of responses by [1DMe]NPYF, a neuropeptide FF analogue
    • A. Pertovaara, U. Keski-vakkuri, J. Kalmari, H. Wei, and P. Panula Response properties of neurons in the rostroventromedial medulla of neuropathic rats: attempted modulation of responses by [1DMe]NPYF, a neuropeptide FF analogue Neuroscience 2001 2001 457 468
    • (2001) Neuroscience , vol.2001 , pp. 457-468
    • Pertovaara, A.1    Keski-Vakkuri, U.2    Kalmari, J.3    Wei, H.4    Panula, P.5
  • 39
    • 0036603005 scopus 로고    scopus 로고
    • Chronic pain and medullary descending facilitation
    • F. Porreca, M.H. Ossipov, and G.F. Gebhart Chronic pain and medullary descending facilitation Trends Neurosci 25 2002 319 325
    • (2002) Trends Neurosci , vol.25 , pp. 319-325
    • Porreca, F.1    Ossipov, M.H.2    Gebhart, G.F.3
  • 40
    • 0028202756 scopus 로고
    • Serotonin immunoreactivity is contained in one physiological cell class in the rat rostral ventromedial medulla
    • S.B. Potrebic, H.L. Fields, and P. Mason Serotonin immunoreactivity is contained in one physiological cell class in the rat rostral ventromedial medulla J Neurosci 14 1994 1655 1665
    • (1994) J Neurosci , vol.14 , pp. 1655-1665
    • Potrebic, S.B.1    Fields, H.L.2    Mason, P.3
  • 41
    • 0024564499 scopus 로고
    • Tooth pulp stimulation advances both medullary off-cell pause and tail flick
    • F. Ramirez, and H. Vanegas Tooth pulp stimulation advances both medullary off-cell pause and tail flick Neurosci Lett 100 1989 153 156
    • (1989) Neurosci Lett , vol.100 , pp. 153-156
    • Ramirez, F.1    Vanegas, H.2
  • 42
    • 52149123505 scopus 로고    scopus 로고
    • Rostral ventral medulla modulation of the visceromotor reflex evoked by urinary bladder distension in female rats
    • A. Randich, H. Mebane, J.J. Deberry, and T.J. Ness Rostral ventral medulla modulation of the visceromotor reflex evoked by urinary bladder distension in female rats J Pain 9 2008 920 926
    • (2008) J Pain , vol.9 , pp. 920-926
    • Randich, A.1    Mebane, H.2    Deberry, J.J.3    Ness, T.J.4
  • 43
    • 0032735538 scopus 로고    scopus 로고
    • An improved method for assessing mechanical allodynia in the rat
    • K. Ren An improved method for assessing mechanical allodynia in the rat Physiol Behav 67 1999 711 716
    • (1999) Physiol Behav , vol.67 , pp. 711-716
    • Ren, K.1
  • 44
    • 0029862244 scopus 로고    scopus 로고
    • Enhanced descending modulation of nociception in rats with persistent hindpaw inflammation
    • K. Ren, and R. Dubner Enhanced descending modulation of nociception in rats with persistent hindpaw inflammation J Neurophysiol 76 1996 3025 3037
    • (1996) J Neurophysiol , vol.76 , pp. 3025-3037
    • Ren, K.1    Dubner, R.2
  • 45
    • 0036844495 scopus 로고    scopus 로고
    • Descending modulation in persistent pain: An update
    • K. Ren, and R. Dubner Descending modulation in persistent pain: an update PAIN® 100 2002 1 6
    • (2002) PAIN® , vol.100 , pp. 1-6
    • Ren, K.1    Dubner, R.2
  • 46
    • 0026709480 scopus 로고
    • The effects of a non-competitive NMDA receptor antagonist, mk-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation
    • K. Ren, J.L. Hylden, G.M. Williams, M.A. Ruda, and R. Dubner The effects of a non-competitive NMDA receptor antagonist, mk-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation PAIN® 50 1992 331 344
    • (1992) PAIN® , vol.50 , pp. 331-344
    • Ren, K.1    Hylden, J.L.2    Williams, G.M.3    Ruda, M.A.4    Dubner, R.5
  • 47
    • 67651154614 scopus 로고    scopus 로고
    • Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity
    • J. Roberts, M.H. Ossipov, and F. Porreca Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity Eur J Neurosci 30 2009 229 241
    • (2009) Eur J Neurosci , vol.30 , pp. 229-241
    • Roberts, J.1    Ossipov, M.H.2    Porreca, F.3
  • 48
    • 74749100610 scopus 로고    scopus 로고
    • Role of RVM neurons in capsaicin-evoked visceral nociception and referred hyperalgesia
    • R. Sanoja, V. Tortorici, C. Fernandez, T.J. Price, and F. Cervero Role of RVM neurons in capsaicin-evoked visceral nociception and referred hyperalgesia Eur J Pain 14 2010 120 129
    • (2010) Eur J Pain , vol.14 , pp. 120-129
    • Sanoja, R.1    Tortorici, V.2    Fernandez, C.3    Price, T.J.4    Cervero, F.5
  • 49
    • 43549083240 scopus 로고    scopus 로고
    • Inflammation-induced changes in rostral ventromedial medulla mu and kappa opioid receptor mediated antinociception
    • R.J. Schepers, J.L. Mahoney, and T.S. Shippenberg Inflammation-induced changes in rostral ventromedial medulla mu and kappa opioid receptor mediated antinociception PAIN® 136 2008 320 330
    • (2008) PAIN® , vol.136 , pp. 320-330
    • Schepers, R.J.1    Mahoney, J.L.2    Shippenberg, T.S.3
  • 50
    • 28844437127 scopus 로고    scopus 로고
    • Trigeminal transition zone/rostral ventromedial medulla connections and facilitation of orofacial hyperalgesia after masseter inflammation in rats
    • S. Sugiyo, M. Takemura, R. Dubner, and K. Ren Trigeminal transition zone/rostral ventromedial medulla connections and facilitation of orofacial hyperalgesia after masseter inflammation in rats J Comp Neurol 493 2005 510 523
    • (2005) J Comp Neurol , vol.493 , pp. 510-523
    • Sugiyo, S.1    Takemura, M.2    Dubner, R.3    Ren, K.4
  • 51
    • 0034717563 scopus 로고    scopus 로고
    • Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation
    • R. Terayama, Y. Guan, R. Dubner, and K. Ren Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation Neuroreport 11 2000 1915 1919
    • (2000) Neuroreport , vol.11 , pp. 1915-1919
    • Terayama, R.1    Guan, Y.2    Dubner, R.3    Ren, K.4
  • 52
    • 79955722091 scopus 로고    scopus 로고
    • Inflammatory pain unmasks heterosynaptic facilitation in lamina i neurokinin 1 receptor-expressing neurons in rat spinal cord
    • C. Torsney Inflammatory pain unmasks heterosynaptic facilitation in lamina I neurokinin 1 receptor-expressing neurons in rat spinal cord J Neurosci 31 2011 5158 5168
    • (2011) J Neurosci , vol.31 , pp. 5158-5168
    • Torsney, C.1
  • 53
    • 9644279795 scopus 로고    scopus 로고
    • Descending control of persistent pain: Inhibitory or facilitatory?
    • H. Vanegas, and H.-G. Schaible Descending control of persistent pain: inhibitory or facilitatory? Brain Res Rev 46 2004 295 309
    • (2004) Brain Res Rev , vol.46 , pp. 295-309
    • Vanegas, H.1    Schaible, H.-G.2
  • 54
    • 33744518427 scopus 로고    scopus 로고
    • Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis
    • L.P. Vera-Portocarrero, J.Y. Xie, J. Kowal, M.H. Ossipov, T. King, and F. Porreca Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis Gastroenterology 130 2006 2155 2164
    • (2006) Gastroenterology , vol.130 , pp. 2155-2164
    • Vera-Portocarrero, L.P.1    Xie, J.Y.2    Kowal, J.3    Ossipov, M.H.4    King, T.5    Porreca, F.6
  • 55
    • 0033023451 scopus 로고    scopus 로고
    • Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation
    • F. Wei, R. Dubner, and K. Ren Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation PAIN® 80 1999 127 141
    • (1999) PAIN® , vol.80 , pp. 127-141
    • Wei, F.1    Dubner, R.2    Ren, K.3
  • 56
    • 0028128856 scopus 로고
    • Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation
    • C.J. Woolf, P. Shortland, and L.G. Sivilotti Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation PAIN® 58 1994 141 155
    • (1994) PAIN® , vol.58 , pp. 141-155
    • Woolf, C.J.1    Shortland, P.2    Sivilotti, L.G.3
  • 57
    • 12144265144 scopus 로고    scopus 로고
    • Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance
    • J.Y. Xie, D.S. Herman, C.O. Stiller, L.R. Gardell, M.H. Ossipov, J. Lai, F. Porreca, and T.W. Vanderah Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance J Neurosci 25 2005 409 416
    • (2005) J Neurosci , vol.25 , pp. 409-416
    • Xie, J.Y.1    Herman, D.S.2    Stiller, C.O.3    Gardell, L.R.4    Ossipov, M.H.5    Lai, J.6    Porreca, F.7    Vanderah, T.W.8
  • 58
    • 33846069212 scopus 로고    scopus 로고
    • NMDA receptor-mediated activation of medullary pro-nociceptive neurons is required for secondary thermal hyperalgesia
    • M. Xu, C.J. Kim, M.J. Neubert, and M.M. Heinricher NMDA receptor-mediated activation of medullary pro-nociceptive neurons is required for secondary thermal hyperalgesia PAIN® 127 2007 253 262
    • (2007) PAIN® , vol.127 , pp. 253-262
    • Xu, M.1    Kim, C.J.2    Neubert, M.J.3    Heinricher, M.M.4
  • 59
    • 0030275438 scopus 로고    scopus 로고
    • Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Behavioral evidence
    • D.C. Yeomans, V. Pirec, and H.K. Proudfit Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: behavioral evidence PAIN® 68 1996 133 140
    • (1996) PAIN® , vol.68 , pp. 133-140
    • Yeomans, D.C.1    Pirec, V.2    Proudfit, H.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.