Effect of repeated Campylobacter jejuni infection on gut flora and mucosal defense in a rat model of post infectious functional and microbial bowel changes

Neurogastroenterology and Motility

Volumn 25, Issue 6, 2013, Pages 529-e372

  Sung, J ^a,b   Morales, W ^a   Kim, G ^a   Pokkunuri, V ^a   Weitsman, S ^a   Rooks, E ^a   Marsh, Z ^a   Barlow, G M ^a   Chang, C ^a   Pimentel, M ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b Chungnam National University   (South Korea)

Author keywords

Campylobacter jejuni; Cytokines; Irritable bowel syndrome; Mucosal defense; Small intestinal bacterial overgrowth

Indexed keywords

BETA DEFENSIN; BETA DEFENSIN 2; BETA DEFENSIN 6; CYTOKINE; INTERLEUKIN 8; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL OVERGROWTH; CAMPYLOBACTER ENTERITIS; CONTROLLED STUDY; FECES ANALYSIS; IMMUNITY; INFECTION RISK; INTESTINE FLORA; INTESTINE FUNCTION; MALE; METHANOBREVIBACTER SMITHII; NONHUMAN; PRIORITY JOURNAL; RAT; REINFECTION;

EID: 84878011115     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12118     Document Type: Article

References (49)

1. Pimentel M. Evaluating a bacterial hypothesis in IBS using a modification of Koch's postulates: Part 1. Am J Gastroenterol 2010; 105: 718-21.
2. Pimentel M, Lembo A, Chey WD et al. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med 2011; 364: 22-32.
3. Spiller RC, Jenkins D, Thornley JP et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut 2000; 47: 804-11.
4. Mearin F, Perez-Oliveras M, Perello A et al. Dyspepsia and irritable bowel syndrome after a Salmonella gastroenteritis outbreak: One-year follow-up cohort study. Gastroenterology 2005; 129: 98-104.
5. Okhuysen PC, Jiang ZD, Carlin L, Forbes C, DuPont HL. Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico. Am J Gastroenterol 2004; 99: 1774-8.
6. Ji S, Park H, Lee D, Song YK, Choi JP, Lee SI. Post-infectious irritable bowel syndrome in patients with Shigella infection. J Gastroenterol Hepatol 2005; 20: 381-6.
7. Halvorson HA, Schlett CD, Riddle MS. Postinfectious irritable bowel syndrome-a meta-analysis. Am J Gastroenterol 2006; 101: 1894-9; quiz 942.
8. Thabane M, Kottachchi DT, Marshall JK. Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome. Aliment Pharmacol Ther 2007; 26: 535-44.
9. Pimentel M, Chatterjee S, Chang C et al. A new rat model links two contemporary theories in irritable bowel syndrome. Dig Dis Sci 2008; 53: 982-9.
10. Brint EK, MacSharry J, Fanning A, Shanahan F, Quigley EM. Differential expression of toll-like receptors in patients with irritable bowel syndrome. Am J Gastroenterol 2011; 106: 329-36.
11. Langhorst J, Junge A, Rueffer A et al. Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome. Am J Gastroenterol 2009; 104: 404-10.
12. Liebregts T, Adam B, Bredack C et al. Immune activation in patients with irritable bowel syndrome. Gastroenterology 2007; 132: 913-20.
13. Scully P, McKernan DP, Keohane J et al. Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity. Am J Gastroenterol 2010; 105: 2235-43.
14. Dinan TG, Clarke G, Quigley EM et al. Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: Role of muscarinic receptors. Am J Gastroenterol 2008; 103: 2570-6.
15. Barkhordari E, Rezaei N, Ansaripour B et al. Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome. J Clin Immunol 2010; 30: 74-9.
16. Villani AC, Lemire M, Thabane M et al. Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis. Gastroenterology 2010; 138: 1502-13.
17. Taylor DN, Echeverria P, Pitarangsi C, Seriwatana J, Bodhidatta L, Blaser MJ. Influence of strain characteristics and immunity on the epidemiology of Campylobacter infections in Thailand. J Clin Microbiol 1988; 26: 863-8.
18. Calva JJ, Ruiz-Palacios GM, Lopez-Vidal AB, Ramos A, Bojalil R. Cohort study of intestinal infection with campylobacter in Mexican children. Lancet 1988; 1: 503-6.
19. Oberhelman RA, Gilman RH, Sheen P et al. A placebo-controlled trial of Lactobacillus GG to prevent diarrhea in undernourished Peruvian children. J Pediatr 1999; 134: 15-20.
20. Taylor DN, Perlman DM, Echeverria PD, Lexomboon U, Blaser MJ. Campylobacter immunity and quantitative excretion rates in Thai children. J Infect Dis 1993; 168: 754-8.
21. Coker AO, Isokpehi RD, Thomas BN, Amisu KO, Obi CL. Human campylobacteriosis in developing countries. Emerg Infect Dis 2002; 8: 237-44.
22. Sorokin M, Usein CR, Irimia M, Damian M. A laboratory-based survey of Campylobacter infections in Prahova County. Roum Arch Microbiol Immunol 2007; 66: 85-9.
23. Vantrappen G, Janssens J, Hellemans J, Ghoos Y. The interdigestive motor complex of normal subjects and patients with bacterial overgrowth of the small intestine. J Clin Invest 1977; 59: 1158-66.
24. Nieuwenhuijs VB, Verheem A, van Duijvenbode-Beumer H et al. The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats. Ann Surg 1998; 228: 188-93.
25. Der-Silaphet T, Malysz J, Hagel S. Larry Arsenault A, Huizinga JD. Interstitial cells of cajal direct normal propulsive contractile activity in the mouse small intestine. Gastroenterology 1998; 114: 724-36.
26. Malysz J, Thuneberg L, Mikkelsen HB, Huizinga JD. Action potential generation in the small intestine of W mutant mice that lack interstitial cells of Cajal. Am J Physiol 1996; 271: G387-99.
27. Ordog T, Ward SM, Sanders KM. Interstitial cells of cajal generate electrical slow waves in the murine stomach. J Physiol 1999; 518: 257-69.
28. Streutker CJ, Huizinga JD, Campbell F, Ho J, Riddell RH. Loss of CD117 (c-kit)- and CD34-positive ICC and associated CD34-positive fibroblasts defines a subpopulation of chronic intestinal pseudo-obstruction. Am J Surg Pathol 2003; 27: 228-35.
29. Vanderwinden JM, Liu H, De Laet MH, Vanderhaeghen JJ. Study of the interstitial cells of Cajal in infantile hypertrophic pyloric stenosis. Gastroenterology 1996; 111: 279-88.
30. Torihashi S, Ward SM, Nishikawa S, Nishi K, Kobayashi S, Sanders KM. c-kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract. Cell Tissue Res 1995; 280: 97-111.
31. Jee SR, Morales W, Low K et al. ICC density predicts bacterial overgrowth in a rat model of post-infectious IBS. World J Gastroenterol 2010; 16: 3680-6.
32. Neal KR, Hebden J, Spiller R. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: Postal survey of patients. BMJ 1997; 314: 779-82.
33. Thornley JP, Jenkins D, Neal K, Wright T, Brough J, Spiller RC. Relationship of Campylobacter toxigenicity in vitro to the development of postinfectious irritable bowel syndrome. J Infect Dis 2001; 184: 606-9.
34. Gwee KA. Irritable bowel syndrome in developing countries-a disorder of civilization or colonization? Neurogastroenterol Motil 2005; 17: 317-24.
35. Dunlop SP, Jenkins D, Neal KR et al. Randomized, double-blind, placebo-controlled trial of prednisolone in post-infectious irritable bowel syndrome. Aliment Pharmacol Ther 2003; 18: 77-84.
36. Barbara G, Stanghellini V, Cremon C et al. Aminosalicylates and other anti-inflammatory compounds for irritable bowel syndrome. Dig Dis 2009; 27: 115-21.
37. Dorofeyev AE, Kiriyan EA, Vasilenko IV, Rassokhina OA, Elin AF. Clinical, endoscopical and morphological efficacy of mesalazine in patients with irritable bowel syndrome. Clin Exp Gastroenterol 2011; 4: 141-53.
38. Spiller R, Campbell E. Post-infectious irritable bowel syndrome. Curr Opin Gastroenterol 2006; 22: 13-7.
39. Kunkel D, Makhani MD, Chong K, Chang C, Pimentel M. Methane on breath testing is associated with constipation: A systematic review and meta-analysis. Gastroenterology 2010; 138: S629.
40. Basseri RJ, Basseri B, Pimentel M et al. Intestinal Methane Production in Obese Individuals Is Associated with a Higher Body Mass Index. Gastroenterol Hepatol (N Y) 2012; 8: 22-8.
41. O'Sullivan M, Clayton N, Breslin NP et al. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil 2000; 12: 449-57.
42. Liang QQ, Xi ZJ, Bian Q et al. Herb formula "Fufangqishe-Pill" prevents upright posture-induced intervertebral disc degeneration at the lumbar in rats. J Pharmacol Sci 2010; 113: 23-31.
43. Palladino MA, Mallonga TA, Mishra MS. Messenger RNA (mRNA) expression for the antimicrobial peptides beta-defensin-1 and beta-defensin-2 in the male rat reproductive tract: Beta-defensin-1 mRNA in initial segment and caput epididymidis is regulated by androgens and not bacterial lipopolysaccharides. Biol Reprod 2003; 68: 509-15.
44. Shi QZ, Wang LW, Zhang W, Gong ZJ. Betaine inhibits toll-like receptor 4 expression in rats with ethanol-induced liver injury. World J Gastroenterol 2010; 16: 897-903.
45. Obata K, Katsura H, Miyoshi K et al. Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury. J Neurochem 2008; 105: 2249-59.
46. Kurihara Y, Endo H, Akahoshi T, Kondo H. Up-regulation of prostaglandin E receptor EP2 and EP4 subtypes in rat synovial tissues with adjuvant arthritis. Clin Exp Immunol 2001; 123: 323-30.
47. Amit-Romach E, Uni Z, Cheled S, Berkovich Z, Reifen R. Bacterial population and innate immunity-related genes in rat gastrointestinal tract are altered by vitamin A-deficient diet. J Nutr Biochem 2009; 20: 70-7.
48. Lee S. Hepatic vascular stress gene expression in the liver response to truama. J Appl Pharmacol 2004; 12: 62-7.
49. del Rey A, Randolf A, Wildmann J, Besedovsky HO, Jessop DS. Re-exposure to endotoxin induces differential cytokine gene expression in the rat hypothalamus and spleen. Brain Behav Immun 2009; 23: 776-83.