메뉴 건너뛰기




Volumn 16, Issue 7, 2010, Pages 897-903

Betaine inhibits toll-like receptor 4 expression in rats with ethanol-induced liver injury

Author keywords

Alcoholic liver injury; Betaine; Expression; Toll like receptor 4

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; BETAINE; ENDOTOXIN; FISH OIL; GAMMA INTERFERON; INTERLEUKIN 18; MESSENGER RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 77449142236     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i7.897     Document Type: Article
Times cited : (39)

References (35)
  • 1
    • 32044448775 scopus 로고    scopus 로고
    • Relation of endotoxin, endotoxin binding proteins and macrophages to severe alcoholic liver injury and multiple organ failure
    • Fukui H. Relation of endotoxin, endotoxin binding proteins and macrophages to severe alcoholic liver injury and multiple organ failure. Alcohol Clin Exp Res 2005; 29: 172S-179S
    • (2005) Alcohol Clin Exp Res , vol.29
    • Fukui, H.1
  • 3
    • 45349092821 scopus 로고    scopus 로고
    • Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells
    • Xu FL, You HB, Li XH, Chen XF, Liu ZJ, Gong JP. Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells. Am J Surg 2008; 196: 139-148
    • (2008) Am J Surg , vol.196 , pp. 139-148
    • Xu, F.L.1    You, H.B.2    Li, X.H.3    Chen, X.F.4    Liu, Z.J.5    Gong, J.P.6
  • 4
    • 30144434916 scopus 로고    scopus 로고
    • Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization
    • Enomoto N, Takei Y, Yamashima S, Ikejima K, Kitamura T, Sato N. Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization. Alcohol Clin Exp Res 2005; 29: 216S-219S
    • (2005) Alcohol Clin Exp Res , vol.29
    • Enomoto, N.1    Takei, Y.2    Yamashima, S.3    Ikejima, K.4    Kitamura, T.5    Sato, N.6
  • 5
    • 33746358175 scopus 로고    scopus 로고
    • Ethanol suppresses LPS-induced Toll-like receptor 4 clustering, reorganization of the actin cytoskeleton, and associated TNF-alpha production
    • Dai Q, Pruett SB. Ethanol suppresses LPS-induced Toll-like receptor 4 clustering, reorganization of the actin cytoskeleton, and associated TNF-alpha production. Alcohol Clin Exp Res 2006; 30: 1436-1444
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1436-1444
    • Dai, Q.1    Pruett, S.B.2
  • 6
    • 24744470271 scopus 로고    scopus 로고
    • Is there a role for cardiomyocyte toll-like receptor 4 in endotoxemia?
    • Tavener SA, Kubes P. Is there a role for cardiomyocyte toll-like receptor 4 in endotoxemia? Trends Cardiovasc Med 2005; 15: 153-157
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 153-157
    • Tavener, S.A.1    Kubes, P.2
  • 8
    • 33644784883 scopus 로고    scopus 로고
    • Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts
    • Dolganiuc A, Bakis G, Kodys K, Mandrekar P, Szabo G. Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts. Alcohol Clin Exp Res 2006; 30: 76-85
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 76-85
    • Dolganiuc, A.1    Bakis, G.2    Kodys, K.3    Mandrekar, P.4    Szabo, G.5
  • 9
    • 19344375848 scopus 로고    scopus 로고
    • Acute exposure to ethanol affects Toll-like receptor signaling and subsequent responses: An overview of recent studies
    • Pruett SB, Zheng Q, Fan R, Matthews K, Schwab C. Acute exposure to ethanol affects Toll-like receptor signaling and subsequent responses: an overview of recent studies. Alcohol 2004; 33: 235-239
    • (2004) Alcohol , vol.33 , pp. 235-239
    • Pruett, S.B.1    Zheng, Q.2    Fan, R.3    Matthews, K.4    Schwab, C.5
  • 10
    • 0344837687 scopus 로고    scopus 로고
    • Synthesis of Toll-like receptor 4 in Kupffer cells and its role in alcohol-induced liver disease
    • Zuo G, Gong J, Liu C, Wu C, Li S, Dai L. Synthesis of Toll-like receptor 4 in Kupffer cells and its role in alcohol-induced liver disease. Chin Med J (Engl) 2003; 116: 297-300
    • (2003) Chin Med J (Engl) , vol.116 , pp. 297-300
    • Zuo, G.1    Gong, J.2    Liu, C.3    Wu, C.4    Li, S.5    Dai, L.6
  • 11
    • 0034950477 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
    • Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG. Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 2001; 34: 101-108
    • (2001) Hepatology , vol.34 , pp. 101-108
    • Uesugi, T.1    Froh, M.2    Arteel, G.E.3    Bradford, B.U.4    Thurman, R.G.5
  • 12
    • 15044351786 scopus 로고    scopus 로고
    • Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alphanaphthylisothiocyanate
    • Kim YC, Jung YS, Kim SK. Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alphanaphthylisothiocyanate. Food Chem Toxicol 2005; 43: 663-670
    • (2005) Food Chem Toxicol , vol.43 , pp. 663-670
    • Kim, Y.C.1    Jung, Y.S.2    Kim, S.K.3
  • 13
    • 14944373556 scopus 로고    scopus 로고
    • A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes
    • Kharbanda KK, Rogers DD 2nd, Mailliard ME, Siford GL, Barak AJ, Beckenhauer HC, Sorrell MF, Tuma DJ. A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes. J Nutr 2005; 135: 519-524
    • (2005) J Nutr , vol.135 , pp. 519-524
    • Kharbanda, K.K.1    Rogers 2nd, D.D.2    Mailliard, M.E.3    Siford, G.L.4    Barak, A.J.5    Beckenhauer, H.C.6    Sorrell, M.F.7    Tuma, D.J.8
  • 15
    • 4544358286 scopus 로고    scopus 로고
    • Betaine in human nutrition
    • Craig SA. Betaine in human nutrition. Am J Clin Nutr 2004; 80: 539-549
    • (2004) Am J Clin Nutr , vol.80 , pp. 539-549
    • Craig, S.A.1
  • 16
    • 30744474176 scopus 로고    scopus 로고
    • Effects of betaine on expression of caspase-12 in ethanol-induced liver injury in rats
    • Zhang P, Gong ZJ. Effects of betaine on expression of caspase-12 in ethanol-induced liver injury in rats. Shijie Huaren Xiaohua Zazhi 2005; 13: 2437-2440
    • (2005) Shijie Huaren Xiaohua Zazhi , vol.13 , pp. 2437-2440
    • Zhang, P.1    Gong, Z.J.2
  • 17
    • 77449114406 scopus 로고    scopus 로고
    • Effects of Betaine on hyperhomocysteinemia and lipid peroxidation in rats with ethanol-induced liver injury
    • Zhang P, Gong ZJ, Wang LW, Sun XM, Zhou XR. Effects of Betaine on hyperhomocysteinemia and lipid peroxidation in rats with ethanol-induced liver injury. Zhongxiyi Jiehe Ganbing Zazhi 2006; 16: 30-32
    • (2006) Zhongxiyi Jiehe Ganbing Zazhi , vol.16 , pp. 30-32
    • Zhang, P.1    Gong, Z.J.2    Wang, L.W.3    Sun, X.M.4    Zhou, X.R.5
  • 18
    • 44349124501 scopus 로고    scopus 로고
    • Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver
    • Ji C, Shinohara M, Vance D, Than TA, Ookhtens M, Chan C, Kaplowitz N. Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver. Alcohol Clin Exp Res 2008; 32: 1049-1058
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 1049-1058
    • Ji, C.1    Shinohara, M.2    Vance, D.3    Than, T.A.4    Ookhtens, M.5    Chan, C.6    Kaplowitz, N.7
  • 19
    • 33748439116 scopus 로고    scopus 로고
    • Betaine resolves severe alcohol-induced hepatitis and steatosis following liver transplantation
    • Samara K, Liu C, Soldevila-Pico C, Nelson DR, Abdelmalek MF. Betaine resolves severe alcohol-induced hepatitis and steatosis following liver transplantation. Dig Dis Sci 2006; 51: 1226-1229
    • (2006) Dig Dis Sci , vol.51 , pp. 1226-1229
    • Samara, K.1    Liu, C.2    Soldevila-Pico, C.3    Nelson, D.R.4    Abdelmalek, M.F.5
  • 20
    • 34247558033 scopus 로고    scopus 로고
    • Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: Effects on protein-L-isoaspartyl methyltransferase activity
    • Kharbanda KK, Mailliard ME, Baldwin CR, Sorrell MF, Tuma DJ. Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity. J Hepatol 2007; 46: 1119-1125
    • (2007) J Hepatol , vol.46 , pp. 1119-1125
    • Kharbanda, K.K.1    Mailliard, M.E.2    Baldwin, C.R.3    Sorrell, M.F.4    Tuma, D.J.5
  • 21
    • 0037960128 scopus 로고    scopus 로고
    • Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice
    • Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology 2003; 124: 1488-1499
    • (2003) Gastroenterology , vol.124 , pp. 1488-1499
    • Ji, C.1    Kaplowitz, N.2
  • 22
    • 0036017172 scopus 로고    scopus 로고
    • Role of Kupffer cells in alcoholic hepatitis
    • Nanji AA. Role of Kupffer cells in alcoholic hepatitis. Alcohol 2002; 27: 13-15
    • (2002) Alcohol , vol.27 , pp. 13-15
    • Nanji, A.A.1
  • 24
    • 33644655384 scopus 로고    scopus 로고
    • Effect of alcohol consumption on the gut
    • Rajendram R, Preedy VR. Effect of alcohol consumption on the gut. Dig Dis 2005; 23: 214-221
    • (2005) Dig Dis , vol.23 , pp. 214-221
    • Rajendram, R.1    Preedy, V.R.2
  • 25
    • 0342699553 scopus 로고    scopus 로고
    • Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease
    • Parlesak A, Schäfer C, Schütz T, Bode JC, Bode C. Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease. J Hepatol 2000; 32: 742-747
    • (2000) J Hepatol , vol.32 , pp. 742-747
    • Parlesak, A.1    Schäfer, C.2    Schütz, T.3    Bode, J.C.4    Bode, C.5
  • 26
    • 0035684037 scopus 로고    scopus 로고
    • Expression of lipopolysaccharide binding protein and its receptor CD14 in experimental alcoholic liver disease
    • Zuo GQ, Gong JP, Liu CA, Li SW, Wu XC, Yang K, Li Y. Expression of lipopolysaccharide binding protein and its receptor CD14 in experimental alcoholic liver disease. World J Gastroenterol 2001; 7: 836-840
    • (2001) World J Gastroenterol , vol.7 , pp. 836-840
    • Zuo, G.Q.1    Gong, J.P.2    Liu, C.A.3    Li, S.W.4    Wu, X.C.5    Yang, K.6    Li, Y.7
  • 29
  • 31
    • 0036606913 scopus 로고    scopus 로고
    • Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster
    • Triantafilou M, Triantafilou K. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol 2002; 23: 301-304
    • (2002) Trends Immunol , vol.23 , pp. 301-304
    • Triantafilou, M.1    Triantafilou, K.2
  • 33
    • 0036067659 scopus 로고    scopus 로고
    • Toll receptors, CD14, and macrophage activation and deactivation by LPS
    • Dobrovolskaia MA, Vogel SN. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect 2002; 4: 903-914
    • (2002) Microbes Infect , vol.4 , pp. 903-914
    • Dobrovolskaia, M.A.1    Vogel, S.N.2
  • 34
    • 0034819316 scopus 로고    scopus 로고
    • Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4 Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations
    • Muta T, Takeshige K. Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4 Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations. Eur J Biochem 2001; 268: 4580-4589
    • (2001) Eur J Biochem , vol.268 , pp. 4580-4589
    • Muta, T.1    Takeshige, K.2
  • 35
    • 33751531458 scopus 로고    scopus 로고
    • Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: Possible involvement of CD14 and TLR-4 downregulation on Kupffer cells
    • Miyaso H, Morimoto Y, Ozaki M, Haga S, Shinoura S, Choda Y, Murata H, Katsuno G, Huda K, Takahashi H, Tanaka N, Iwagaki H. Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: possible involvement of CD14 and TLR-4 downregulation on Kupffer cells. Dig Dis Sci 2006; 51: 2007-2012
    • (2006) Dig Dis Sci , vol.51 , pp. 2007-2012
    • Miyaso, H.1    Morimoto, Y.2    Ozaki, M.3    Haga, S.4    Shinoura, S.5    Choda, Y.6    Murata, H.7    Katsuno, G.8    Huda, K.9    Takahashi, H.10    Tanaka, N.11    Iwagaki, H.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.