Chromatographic separation of piracetam and its metabolite in a mixture of microsomal preparations, followed by an MS/MS analysis

European Journal of Medicinal Chemistry

Volumn 65, Issue , 2013, Pages 94-101

  Sahu, Kapendra ^a   Siddiqui, Anees A ^a   Shaharyar, Mohammad ^a   Ahmad, Niyaz ^a   Anwar, Mohammad ^a   Ahmad, Farhan J ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Human liver microsomes; Metabolic pathway; Pharmacokinetics of the generated metabolite; Piracetam metabolism; UPLC MS MS; Validation

Indexed keywords

CYTOCHROME P450; DRUG METABOLITE; PIRACETAM;

ANIMAL TISSUE; ARTICLE; COMPUTER MODEL; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG SPECIFICITY; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME METABOLISM; MASS SPECTROMETRY; NONHUMAN; RAT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84878007656     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.04.053     Document Type: Article

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