Determination of piracetam in rat plasma by LC-MS/MS and its application to pharmacokinetics

Biomedical Chromatography

Volumn 24, Issue 10, 2010, Pages 1108-1112

  Wang, Xianqin ^a   Zhu, Jiayin ^a   Xu, Renai ^a   Yang, Xuezhi ^a   Wu, Haiya ^a   Lin, Dan ^a   Ye, Faqing ^a   Hu, Lufeng ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

LC MS MS; Pharmacokinetics; Piracetam; Rat plasma

Indexed keywords

BODY FLUIDS; DATA ACQUISITION; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRECIPITATION (CHEMICAL); RATS; TRICHLOROACETIC ACID;

CONCENTRATION RANGES; INTERNAL STANDARDS; ITS APPLICATIONS; LC-MS-MS; LC.MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; PIRACETAM; RAT PLASMA; SELECTIVE LIQUID CHROMATOGRAPHY;

PHARMACOKINETICS;

ACETONITRILE; FORMIC ACID; OXIRACETAM; PIRACETAM;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; SENSITIVITY AND SPECIFICITY; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

RATTUS;

EID: 77957295932     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1412     Document Type: Article

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