Is oxytocin a therapeutic factor for ischemic heart disease?

Peptides

Volumn 45, Issue , 2013, Pages 66-72

  Alizadeh, Ali Mohammad ^a   Mirzabeglo, Parasto ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cardioprotection; Ischemic heart disease; Oxytocin; Review

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ATRIAL NATRIURETIC FACTOR; GLUCOSE; NITRIC OXIDE SYNTHASE; OXYTOCIN; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; CARDIOTONIC AGENT;

ACUTE STRESS; APOPTOSIS; DRUG EFFECT; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART PROTECTION; HEMODYNAMIC PARAMETERS; HUMAN; ISCHEMIC HEART DISEASE; MEMBRANE DEPOLARIZATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; ARRHYTHMIAS, CARDIAC; CORONARY ARTERY DISEASE; HEART MUSCLE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NECROSIS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ARRHYTHMIAS, CARDIAC; CARDIOTONIC AGENTS; CORONARY ARTERY DISEASE; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; OXYTOCIN;

EID: 84878007371     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.04.016     Document Type: Review

References (103)

1. A.M. Alizadeh, M. Faghihi, V. Khori, and M. Mohseniki Effect of pre-treatment with oxytocin on cardiac enzymes in regional ischemia-reperfusion injury induced in the rat heart Physiol Pharmacol 15 4 2012 572 582
2. A.M. Alizadeh, M. Faghihi, V. Khori, H. Sohanaki, K. Pourkhalili, and F. Mohammadghasemi Oxytocin protects cardiomyocytes from apoptosis induced by ischemia-reperfusion in rat heart: role of mitochondrial ATP-dependent potassium channel and permeability transition pore Peptides 36 1 2012 71 77
3. A.M. Alizadeh, M. Faghihi, H.R. Sadeghipour, F. Mohammadghasemi, A. Imani, and F. Houshmand Oxytocin protects rat heart against ischemia-reperfusion injury via pathway involving mitochondrial ATP-dependent potassium channel Peptides 31 7 2010 1341 1345
4. A.M. Alizadeh, M. Faghihi, H.R. Sadeghipour, F. Mohammadghasemi, and V. Khori Role of endogenous oxytocin in cardiac ischemic preconditioning Regul Pept 167 1 2011 86 90
5. F.M. Ashcroft Adenosine 5′-triphosphate-sensitive potassium channels Annu Rev Neurosci 11 1988 97 118
6. C.P. Baines, M. Goto, and J.M. Downey Oxygen radicals released during ischemic preconditioning contributes to cardioprotection in the rabbit myocardium J Mol Cell Cardiol 29 1997 207 216 (Pubitemid 27129144)
7. C.P. Baines, J. Zhang, G.W. Wang, Y.T. Zheng, J.X. Xiu, and E.M. Cardwell Mitochondrial PKC epsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKC epsilon-MAPK interactions and differential MAPK activation in PKC epsilon-induced cardioprotection Circ Res 90 4 2002 390 397 (Pubitemid 34633907)
8. I. Bernatova, K.V. Rigatto, M.P. Key, and M. Morris Stress-induced pressor and corticosterone responses in oxytocin-deficient mice Exp Physiol 89 2004 549 557 (Pubitemid 39255726)
9. N.K. Biyiklia, H. Tugtepeb, G. Senerc, A. Velioglu-Oguncd, S. Cetinele, and S. Midillioglue Oxytocin alleviates oxidative renal injury in pyelonephritic rats via a neutrophil-dependent mechanism Peptides 27 2006 2249 2257
10. R. Bolli Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research J Mol Cell Cardiol 33 11 2001 1897 1918 (Pubitemid 33097270)
11. J.P. Brennan, R. Southworth, R.A. Medina, S.M. Davidson, M.R. Duchen, and M.J. Shattock Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation Cardiovasc Res 72 2 2006 313 321 (Pubitemid 44511914)
12. D.A. Brown, and B. O'Rourke Cardiac mitochondria and arrhythmias Cardiovasc Res 88 2 2010 241 249
13. G.C. Brown, and V. Borutaite Nitric oxide and mitochondrial respiration in the heart Cardiovasc Res 75 2 2007 283 290 (Pubitemid 46961922)
14. G.R. Budas, E.N. Churchill, and D. Mochly-Rosen Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury Pharmacol Res 55 2007 523 536 (Pubitemid 46962304)
15. R.O. Cannon 3rd Role of nitric oxide in cardiovascular disease: focus on the endothelium Clin Chem 44 8 Pt 2 1998 1809 1819
16. L.C. Cantley The phosphoinositide 3-kinase pathway Science 296 2002 1655 1657 (Pubitemid 34579158)
17. A. Cassar, D.R. Holmes Jr., C.S. Rihal, and B.J. Gersh Chronic coronary artery disease: diagnosis and management Mayo Clin Proc 84 12 2009 1130 1146
18. J. Chen, H. Shen, Y. Nagasawa, K. Mitsui, K. Tsurugi, and K. Hashimoto Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats J Pharmacol Sci 103 3 2007 317 322 (Pubitemid 46465775)
19. W. Chen, S. Gabel, C. Steenbergen, and E. Murphy A redox-based mechanism for cardioprotection induced by ischemic preconditioning in perfused rat heart Circ Res 77 2 1995 424 429
20. 2 inhibit the mitochondrial permeability transition J Biol Chem 281 2006 20801 20808 (Pubitemid 44115421)
21. R.H. Costa-E-Sousa, P.P. Pereira, P.F. Oliveira, E.L. Olivares, J.P. Werneck de Castro, and D.B. Mello Cardiac effects of oxytocin: is there a role for this peptide in cardiovascular homeostasis? Regul Pept 132 2005 107 112 (Pubitemid 41607509)
22. H.H. Dale On some physiological actions of ergot J Physiol 34 3 1906 163 206
23. B.A. Danalache, J. Paquin, W. Donghao, R. Grygorczyk, J.C. Moore, and C.L. Mummery Nitric oxide signaling in oxytocin-mediated cardiomyogenesis Stem Cells 25 3 2007 679 688 (Pubitemid 46354227)
24. B. Das, and Sarkar Ch Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial KATP channel activation in the in vivo anesthetized rabbit heart? Life Sci 90 2012 763 769
25. V. Du Vigneaud, C. Ressler, J.M. Swan, C.W. Roberts, and P.G. Katsoyannis The synthesis of oxytocin J Am Chem Soc 76 1954 3115 3121
26. D.J. Duncker, and R.J. Bache Regulation of coronary blood flow during exercise Physiol Rev 88 3 2008 1009 1086
27. F. Dusunceli, S.O. Iseri, F. Ercan, N. Gedik, and C. Yegen Oxytocin alleviates hepatic ischemia-reperfusion injury in rats Peptides 29 2008 1216 1222
28. G. Erkanli Senturk, K. Erkanli, U. Aydin, D. Yucel, N. Isiksacan, and F. Ercan The protective effect of oxytocin on ischemia/reperfusion injury in rat urinary bladder Peptides 40C 2012 82 88
29. M. Faghihi, A.M. Alizadeh, V. Khori, H. Khodayari, and S. Moradi Preconditioning effects of oxytocin in reducing cardiac arrhythmias in a rat heart regional ischemia-reperfusion model Physiol Pharmacol 16 4 2013 393 403
30. M. Faghihi, A.M. Alizadeh, V. Khori, M. Latifpour, and S. Khodayari The role of nitric oxide, reactive oxygen species, and protein kinase C in oxytocin-induced cardioprotection in ischemic rat heart Peptides 37 2 2012 314 319
31. A.L. Favaretto, G.O. Ballejo, W.I. Albuquerque-Araújo, J. Gutkowska, J. Antunes-Rodrigues, and S.M. McCann Oxytocin releases atrial natriuretic peptide from rat atria in vitro that exerts negative inotropic and chronotropic action Peptides 18 9 1997 1377 1381 (Pubitemid 27519748)
32. P. Ferdinandy, R. Schulz, and G.F. Baxter Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning Pharmacol Rev 59 4 2007 418 458
33. M. Florian, M. Jankowski, and J. Gutkowska Oxytocin increases glucose uptake in neonatal rat cardiomyocytes Endocrinology 151 2 2010 482 491
34. R.A. Forbes, C. Steenbergen, and E. Murphy Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism Circ Res 88 8 2001 802 809 (Pubitemid 32429976)
35. + channels in mitochondrial inner membrane Am J Physiol Heart Circ Physiol 293 2007 322 332
36. P.Z. Gerczuk, and R.A. Kloner An update on cardioprotection; a review of the latest adjunctive therapies to limit myocardial infarction size in clinical trials J Am Coll Cardiol 59 2012 969 978
37. C. Gill, R. Mestril, and A. Samali Losing heart: the role of apoptosis in heart disease - a novel therapeutic target? FASEB J 16 2 2002 135 146 (Pubitemid 34113007)
38. G. Gimpl, and F. Fahrenholz The oxytocin receptor system: structure, function, and regulation Physiol Rev 81 2001 629 683 (Pubitemid 32267075)
39. K.M. Grewen, and K.C. Light Plasma oxytocin is related to lower cardiovascular and sympathetic reactivity to stress Biol Psychol 87 3 2011 340 349
40. J. Gutkowska, M. Jankowski, C. Lambert, S. Mukaddam-Daher, H.H. Zingg, and S.M. McCann Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart Proc Natl Acad Sci U S A 94 21 1997 11704 11709 (Pubitemid 27451062)
41. J. Gutkowska, M. Jankowski, S. Mukaddam-Daher, and S.M. McCann Oxytocin is a cardiovascular hormone Braz J Med Biol Res 33 2000 625 633
42. A.P. Halestrap, S.J. Clarke, and I. Khaliulin The role of mitochondria in protection of the heart by preconditioning Biochim Biophys Acta 1767 8 2007 1007 1031 (Pubitemid 47101788)
43. + channel activation by nitric oxide and protein kinase G in rabbit ventricular myocytes Am J Physiol Heart Circ Physiol 283 4 2002 H1545 H1554
44. P.J. Hanley, and J. Daut KATP channels and preconditioning: a re-examination of the role of mitochondrial K(ATP) channels and an overview of alternative mechanisms J Mol Cell Cardiol 39 1 2005 17 50 (Pubitemid 40836043)
45. D.J. Hausenloy, and D.M. Yellon Preconditioning and postconditioning. United at reperfusion Pharmacol Ther 116 2007 173 191
46. W.W. Hay Jr. Recent observations on the regulation of fetal metabolism by glucose J Physiol 572 2006 17 24
47. G. Heusch, K. Boengler, and R. Schulz Cardioprotection nitric oxide, protein kinases, and mitochondria Circulation 118 2008 1915 1919
48. G. Heusch Heart rate in the pathophysiology of coronary blood flow and myocardial ischemia: benefit from selective bradycardic agents Br J Pharmacol 153 8 2008 1589 1601 (Pubitemid 351535988)
49. K. Inagaki, E. Churchill, and D. Mochly-Rosen Epsilon protein kinase C as a potential therapeutic target for the ischemic heart Cardiovasc Res 70 2006 222 230
50. S.O. Işeri, G. Sener, B. Saglam, N. Gedik, F. Ercan, and B.C. Yegen Oxytocin protects against sepsis-induced multiple organ damage: role of neutrophils J Surg Res 126 1 2005 73 81 (Pubitemid 40726249)
51. M. Jankowski, V. Bissonauth, L. Gao, M. Gangal, D. Wang, and B. Danalache Anti-inflammatory effect of oxytocin in rat myocardial infarction Basic Res Cardiol 105 2 2010 205 218
52. M. Jankowski, F. Hajjar, S.A. Kawas, S. Mukaddam-Daher, G. Hoffman, and S.M. McCann Rat heart: a site of oxytocin production and action Proc Natl Acad Sci U S A 95 24 1998 14558 14563 (Pubitemid 28549406)
53. M. Jankowski, D. Wang, F. Hajjar, S. Mukaddam-Daher, S.M. McCann, and J. Gutkowska Oxytocin and its receptors are synthesized in the rat vasculature Proc Natl Acad Sci U S A 97 2000 6207 6211 (Pubitemid 30367548)
54. M. Jankowski, N. Noiseux, and J. Gutkowska Oxytocin stimulates cardiomyogenesis and cardioprotection via stem cells activation Endocr Abstr 29 2012 P291
55. S. Javadov, and M. Karmazyn Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection Cell Physiol Biochem 20 1-4 2007 1 22 (Pubitemid 46956808)
56. L.G. Kevin, E. Novalija, and D.F. Stowe Reactive oxygen species as mediators of cardiac injury and protection: the relevance to anesthesia practice Anesth Analg 101 5 2005 1275 1287 (Pubitemid 41531857)
57. H.K. Kim, V.T. Thu, H.J. Heo, N. Kim, and J. Han Cardiac proteomic responses to ischemia-reperfusion injury and ischemic preconditioning Expert Rev Proteomics 8 2 2011 241 261
58. 2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion Am J Physiol Heart Circ Physiol 290 5 2006 H2024 H2034
59. Y.S. Kim, Y. Ahn, J.S. Kwon, Y.K. Cho, M.H. Jeong, and J.G. Cho Priming of mesenchymal stem cells with oxytocin enhances the cardiac repair in ischemia/reperfusion injury Cells Tissues Organs 195 5 2012 428 442
60. S. Kimura, G.X. Zhang, A. Nishiyama, T. Shokoji, L. Yao, and Y.Y. Fan Role of NAD(P)H oxidase-and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin Hypertension 45 2005 860 866 (Pubitemid 40628929)
61. D.M. Kopustinskiene, J. Liobikas, K. Skemiene, F. Malinauskas, and A. Toleikis Direct effects of K(ATP)channel openers pinacidil and diazoxide on oxidative phosphorylation of mitochondria in situ Cell Physiol Biochem 25 2-3 2010 181 186
62. G. Lebuffe, P.T. Schumacker, Z.H. Shao, T. Anderson, H. Iwase, and T.L. Vanden Hoek ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel Am J Physiol Heart Circ Physiol 284 2003 299 308
63. E.S. Lee, K.O. Uhm, Y.M. Lee, J. Kwon, S.H. Park, and K.H. Soo Oxytocin stimulates glucose uptake in skeletal muscle cells through the calcium-CaMKK-AMPK pathway Regul Pept 151 2008 71 74
64. D.J. Lefer, and A.M. Lefer Nitric oxide homeostasis control as therapy for cardiovascular diseases Cardiovasc Res 27 12 1993 2282
65. H. Liu, B.C. McPherson, X. Zhu, M.L. Da Costa, V. Jeevanandam, and Z. Yao Role of nitric oxide and protein kinase C in ACh-induced cardioprotection Am J Physiol Heart Circ Physiol 281 2001 191 197
66. J. Liu, T. Sato, B. O'Rourke, and E. Marban Mitochondrial ATP dependent potassium channels: novel effectors of cardioprotection Circulation 97 1998 2463 2469 (Pubitemid 28278191)
67. X.L. Ma, A.S. Weyrich, D.J. Lefer, and A.M. Lefer Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium Circ Res 72 2 1993 403 412 (Pubitemid 23024528)
68. D. Malinska, S.R. Mirandola, and W.S. Kunz Mitochondrial potassium channels and reactive oxygen species FEBS Lett 584 10 2010 2043 2048
69. J.C. Martinou, and R.J. Youle Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics Dev Cell 21 1 2011 92 101
70. P.B. Massion, O. Feron, C. Dessy, and J.L. Balligand Nitric oxide and cardiac function ten years after, and continuing Circ Res 93 2003 388 398 (Pubitemid 37100003)
71. J. Matejikova, J. Kucharska, M. Pinterova, D. Pancza, and T. Ravingerova Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial KATP channels and reactive oxygen species Physiol Res 58 1 2009 9 19
72. K. Matsushita, S. Iwanaga, T. Oda, K. Kimura, M. Shimada, and M. Sano Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis Lab Invest 85 10 2005 1210 1223 (Pubitemid 41348637)
73. K. Matsuura, T. Nagai, N. Nishigaki, T. Oyama, J. Nishi, and H. Wada Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes J Biol Chem 279 12 2004 11384 11391 (Pubitemid 38401637)
74. B.L. Maximilian Myocardial ischemia and reperfusion injury Cardiovasc Pathol 14 2005 170 175
75. M. Moghimian, M. Faghihi, S.M. Karimian, and A. Imani The effect of acute stress exposure on ischemia and reperfusion injury in rat heart: role of oxytocin Stress 15 4 2012 385 392
76. E. Murphy, and C. Steenbergen Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury Physiol Rev 88 2008 581 609 (Pubitemid 351520088)
77. C.E. Murray, R.B. Jennings, and K.A. Reimer Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium Circulation 74 1986 1124 1136 (Pubitemid 17174962)
78. C.L. Murriel, and D. Mochly-Rosen Opposing roles of delta and epsilon PKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery Arch Biochem Biophys 420 2003 246 254 (Pubitemid 37491108)
79. I.D. Neumann, A. Wigger, L. Torner, F. Holsboer, and R. Landgraf Brain oxytocin inhibits basal and stress-induced activity of the hypothalamo- pituitary-adrenal axis in male and female rats: partial action within the paraventricular nucleus J Neuroendocrinol 12 2000 235 243 (Pubitemid 30156515)
80. C.G. Nichols, and W.J. Lederer Adenosine triphosphate-sensitive potassium channels in the cardiovascular system Am J Physiol 261 1991 H1675 H1686
81. O. Oldenburg, Q. Qin, T. Krieg, X.M. Yang, S. Philipp, and S.D. Critz Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection Am J Physiol Heart Circ Physiol 286 2004 468 476
82. M. Ondrejcakova, T. Ravingerrova, J. Bakos, D. Pancza, and D. Jezova Oxytocin exerts protective effects on in vitro myocardial injury induced by ischemia and reperfusion Can J Physiol Pharmacol 87 2009 137 142
83. + channels and their role in cardioprotection Circ Res 94 4 2004 420 432 (Pubitemid 38326277)
84. H. Otani Ischemic preconditioning: from molecular mechanisms to therapeutic opportunities Antioxid Redox Signal 10 2 2008 207 247
85. T. Pain, X.M. Yang, S.D. Critz, Y. Yue, A. Nakano, and G.S. Liu Opening of mitochondrial KATP channels triggers the preconditioned state by generating free radicals Circ Res 87 6 2000 460 466
86. J. Paquin, B.A. Danalache, M. Jankowski, S.M. McCann, and J. Gutkowska Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes Proc Natl Acad Sci U S A 99 14 2002 9550 9555 (Pubitemid 34764650)
87. H. Pournajafi-Nazarloo, A. Perry, L. Partoo, E. Papademetriou, F. Azizi, and C.S. Carter Neonatal oxytocin treatment modulates oxytocin receptor, atrial natriuretic peptide, nitric oxide synthase and estrogen receptor mRNAs expression in rat heart Peptides 28 2007 1170 1177 (Pubitemid 46843397)
88. R.D. Rakhit, R.J. Edwards, and M.S. Marber Nitric oxide, nitrates and ischemic preconditioning Cardiovasc Res 43 3 1999 621 627 (Pubitemid 29369260)
89. J.C. Reed Mechanisms of apoptosis Am J Pathol 157 5 2000 1415 1430
90. R.D. Russ, and B.R. Walker Oxytocin augments baroreflex bradycardia in conscious rats Peptides 15 5 1994 907 912 (Pubitemid 24248415)
91. N. Sasaki, T. Sato, A. Ohler, B. O'Rourke, and E. Marban Activation of mitochondrial ATP-dependent potassium channels by nitric oxide Circulation 101 2000 439 445 (Pubitemid 30067402)
92. R. Schulz, M.V. Cohen, M. Behrends, J.M. Downey, and G. Heusch Signal transduction of ischemic preconditioning Cardiovasc Res 52 2001 181 198 (Pubitemid 33000395)
93. L. Skarka, and B. Ostadal Mitochondrial membrane potential in cardiac myocytes Physiol Res 51 5 2002 425 434 (Pubitemid 36119209)
94. L.C. Thuc, Y. Teshima, N. Takahashi, Y. Nagano-Torigoe, K. Ezaki, and K. Yufu Mitochondrial KATP channels-derived reactive oxygen species activate pro-survival pathway in pravastatin-induced cardioprotection Apoptosis 15 6 2010 669 678
95. H. Tugtepe, G. Sener, N.K. Biyikli, M. Yuksel, S. Cetinel, and N. Gedik The protective effect of oxytocin on renal ischemia/reperfusion injury in rats Regul Pept 140 2007 101 108 (Pubitemid 46418907)
96. T. Ueyama, K. Yoshida, and E. Senba Stress-induced elevation of the ST segment in the rat electrocardiogram is normalized by an adrenoceptor blocker Clin Exp Pharmacol Physiol 27 2000 384 386 (Pubitemid 30313438)
97. Y. Wang, E. Takashi, M. Xu, A. Ayub, and M. Ashraf Downregulation of protein kinase C inhibits activation of mitochondrial KATP channels by diazoxide Circulation 104 2001 85 90 (Pubitemid 32623294)
98. H. Yoshida, Y. Kusama, E. Kodani, M. Yasutake, H. Takano, and H. Atarashi Pharmacological preconditioning with bradykinin affords myocardial protection through NO-dependent mechanisms Int Heart J 46 2005 877 887
99. N. Zamzami, S.A. Susin, P. Marchetti, T. Hirsch, I. Gomez-Monterrey, and M. Castedo Mitochondrial control of nuclear apoptosis J Exp Med 183 4 1996 1533 1544 (Pubitemid 26134296)
100. M. Zaugg, and M.C. Schaub Signaling and cellular mechanisms in cardiac protection by ischemic and pharmacological preconditioning J Muscle Res Cell Motil 24 2003 219 249 (Pubitemid 37323624)
101. G.X. Zhang, X.M. Lu, S. Kimura, and A. Nishiyama Role of mitochondria in angiotensin II-induced reactive oxygen species and mitogen-activated protein kinase activation Cardiovasc Res 76 2 2007 204 212 (Pubitemid 350198600)
102. L. Zhang, M. Tong, M. Xiao, L. Li, and J. Ding Nitric oxide mediates feedback inhibition in angiotensin II-induced upregulation of vasopressin mRNA Peptides 30 5 2009 913 917
103. D.B. Zorov, C.R. Filburn, L.O. Klotz, J.L. Zweier, and S.J. Sollott Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes J Exp Med 192 2000 1001 1014