Risk of pancreatic cancer in breast cancer families from the breast cancer family registry

Cancer Epidemiology Biomarkers and Prevention

Volumn 22, Issue 5, 2013, Pages 803-811

  Mocci, Evelina ^a   Milne, Roger L ^a,b   Mendez Villamil, Elena Yuste ^a   Hopper, John L ^b   John, Esther M ^c   Andrulis, Irene L ^d   Chung, Wendy K ^e   Daly, Mary ^f   Buys, Saundra S ^g   Malats, Nuria ^a   Goldgar, David E ^h  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MOUNT SINAI HOSPITAL   (Canada)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f FOX CHASE CANCER CENTER   (United States)

^g Departments of Internal Medicine   (United States)

^h UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER REGISTRY; CANCER RISK; COHORT ANALYSIS; CONTROLLED STUDY; FAMILIAL DISEASE; FAMILY HISTORY; FEMALE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PANCREAS CANCER; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

AGED; BREAST NEOPLASMS; FAMILY HEALTH; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; REGISTRIES; RISK ASSESSMENT;

EID: 84877987105     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-12-0195     Document Type: Article

References (36)

1. Raimondi S, Maisonneuve P, Lowenfels AB. Epidemiology of pancreatic cancer: An overview. Nat Rev Gastroenterol Hepatol 2009;6: 699-708.
2. Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, et al. Genetic mutations associated with cigarette smoking in pancreatic cancer. Cancer Res 2009;69:3681-8.
3. Petersen GM, de Andrade M, Goggins M, Hruban RH, Bondy M, Korkzac JF, et al. Pancreatic cancer genetic epidemiology consortium. Cancer Epidemiol Biomarkers Prev 2006;15:704-10.
4. Klein AP, Brune KA, Petersen GM, Goggins M, Tersmette AC, Offerhaus GJ, et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res 2004;64:2634-8.
5. Brune KA, Lau B, Palmisano E, Canto M, Goggins MG, Hruban RH, et al. Importance of age of onset in pancreatic cancer kindreds. J Natl Cancer Inst 2010;102:119-26.
6. Murphy KM, Brune KA, Griffin C, Sollenberg JE, Petersen GM, Bansal R, et al. Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%. Cancer Res 2002;62:3789-93.
7. Hahn SA, Greenhalf B, Ellis I, Sina-Frey M, Rieder H, Korte B, et al. BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst 2003;95:214-21.
8. Couch FJ, Johnson MR, Rabe KG, Brune K, de Andrade M, Goggins M, et al. The prevalence of BRCA2 mutations in familial pancreatic cancer. Cancer Epidemiol Biomarkers Prev 2007;16:342-6.
9. Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, et al. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science 2009;324:217.
10. Slater EP, Langer P, Niemczyk E, Strauch K, Butler J, Habbe N, et al. PALB2 mutations in European familial pancreatic cancer families. Clin Genet 2010;78:490-4.
11. Tischkowitz M, Xia B, Sabbaghian N, Reis-Filho JS,Hamel N, Li G, et al. Analysis of PALB2/FANCN-associated breast cancer families. Proc Natl Acad Sci U S A 2007;104:6788-93.
12. Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy ML, et al. ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov 2012;2:41-6
13. Sy SM, Huen MS, Chen J.PALB2is an integral component of theBRCA complex required for homologous recombination repair. Proc Natl Acad Sci U S A 2009;106:7155-60.
14. van Asperen CJ, Brohet RM, Meijers-Heijboer EJ, Hoogerbrugge N, Verhoef S, Vasen HF, et al. Cancer risks in BRCA2 families: Estimates for sites other than breast and ovary. J Med Genet 2005;42: 711-9.
15. Breast Cancer Linkage Consortium. Cancer risks in BRCA2 mutation carriers. J Natl Cancer Inst 1999;91:1310-6.
16. Risch HA, McLaughlin JR, Cole DE, Rosen B, Bradley L, Fan I, et al. Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: A kin-cohort study in Ontario, Canada. J Natl Cancer Inst 2006;98:1694-706.
17. Iqbal J, Ragone A, Lubinski J, Lynch HT, Moller P, Ghadirian P, et al. The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers. Br J Cancer 2012;107:2005-9.
18. Thompson D, Easton DF. Cancer Incidence in BRCA1 mutation carriers. J Natl Cancer Inst 2002;94:1358-65.
19. JohnEM,Hopper JL,BeckJC, Knight JA,NeuhausenSL,SenieRT, et al. The Breast Cancer Family Registry: An infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer. Breast Cancer Res 2004;6:R375-89.
20. Dite GS, Whittemore AS, Knight JA, John EM, Milne RL, Andrulius IL, et al. Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations. Br J Cancer 2010;103:1103-8.
21. Ott J. Computer-simulation methods in human linkage analysis. Proc Natl Acad Sci U S A 1989;86:4175-8.
22. Antoniou AC, Easton DF. Polygenic inheritance of breast cancer: Implications for design of association studies. Genet Epidemiol 2003; 25:190-202.
23. Hills M, Clayton D. Statistical models in epidemiology. Oxford, United Kingdom: Oxford University Press; 1993.
24. Brose MS, Rebbeck TR, Calzone KA, Stopfer JE, Nathanson KL, Weber BL. Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. J Natl Cancer Inst 2002;94:1365-72.
25. Stadler ZK, Salo-Mullen E, Patil SM, Pietanza MC, Vijai J, Saloustros E, et al. Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer. Cancer 2012;118:493-9.
26. Lorenzo Bermejo J, Hemminki K. Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing. Ann Oncol 2004;15:1834-41.
27. Rahman N, Seal S, Thompson D, Kelly P, Renwick A, Elliott A, et al. PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet 2007;39:165-7.
28. Southey MC, Teo ZL, Dowty JG, Odefrey FA, Park DJ, Tischkowitz M, et al. A PALB2 mutation associated with high risk of breast cancer. Breast Cancer Res 2010;12:R109.
29. Tischkowitz MD, Sabbaghian N, Hamel N, Borgida A, Rosner C, Taherian N, et al. Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer. Gastroenterology 2009;137:1183-6.
30. Hofstatter EW, Domchek SM, Miron A, Garber J, Wang M, Camponeschi K, et al. PALB2 mutations in familial breast and pancreatic cancer. Fam Cancer 2011;10:225-31.
31. Friedenson B. BRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarian. MedGenMed 2005;7:60.
32. Moran A, O'Hara C, Khan S, Shack L, Woodward E, Maher ER, et al. Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations. Fam Cancer 2012;11:235-42.
33. TazikiMHBN, Tadrisee M, Mansourian AR. Esophageal cancer: 5-year survival rate at south-east of Caspian sea of northern Iran. J Cancer Res Ther 2011;7:135-7.
34. Novakovic B, Goldstein AM, Tucker MA. Validation of family history of cancer in deceased family members. J Natl Cancer Inst 1996;88: 1492-3.
35. Airewele G, Adatto P, Cunningham J, Mastromarino C, Spencer C, Sharp M, et al. Family history of cancer in patients with glioma: A validation study of accuracy. J Natl Cancer Inst 1998;90:543-4.
36. Ziogas A, Anton-Culver H. Validation of family history data in cancer family registries. Am J Prev Med 2003;24:190-8.