Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy

Circulation

Volumn 127, Issue 20, 2013, Pages 2047-2055

  Kolachalama, Vijaya B ^a,b   Pacetti, Stephen D ^c   Franses, Joseph W ^a   Stankus, John J ^c   Zhao, Hugh Q ^c   Shazly, Tarek ^a,d   Nikanorov, Alexander ^c   Schwartz, Lewis B ^c   Tzafriri, Abraham R ^a,e   Edelman, Elazer R ^a,f  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^b CHARLES STARK DRAPER LABORATORY   (United States)

^c ABBOTT VASCULAR   (United States)

^d UNIVERSITY OF SOUTH CAROLINA   (United States)

^e CBSET Inc   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

animal model; binding; computational modeling; diffusion; drug coated balloon; peripheral vascular disease; zotarolimus

Indexed keywords

PACLITAXEL; ZOTAROLIMUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; DIFFUSION CHAMBER; DRUG BINDING; DRUG COATED BALLOON; DRUG COATING; DRUG DELIVERY DEVICE; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG RETENTION; DRUG TISSUE LEVEL; DRUG UPTAKE; FEMORAL ARTERY; IMPLANT; IMPLANT DELIVERY DEVICE; IN VIVO STUDY; NONHUMAN; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; SIMULATION; SWINE;

ANIMAL MODEL; BINDING; COMPUTATIONAL MODELING; DIFFUSION; DRUG-COATED BALLOON; PERIPHERAL VASCULAR DISEASE; ZOTAROLIMUS;

ANGIOPLASTY, BALLOON; ANIMALS; DRUG DELIVERY SYSTEMS; FEMALE; FEMORAL ARTERY; MALE; ORGAN CULTURE TECHNIQUES; PACLITAXEL; SIROLIMUS; SWINE; TISSUE DISTRIBUTION;

EID: 84877981464     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.002051     Document Type: Article

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