A theoretical model to characterize the drug release behavior of drug-eluting stents with durable polymer matrix coating

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 1, 2012, Pages 120-124

  Zhao, Hugh Q ^a   Jayasinghe, Dudley ^a   Hossainy, Syed ^a   Schwartz, Lewis B ^a  

^a ABBOTT VASCULAR   (United States)

Author keywords

controlled release; drug diffusion; drug eluting stent; modeling; pharmacokinectics

Indexed keywords

BASIC MECHANISM; CHARACTERISTIC PARAMETER; COATING THICKNESS; CONTROLLED RELEASE; DIFFUSION MODEL; DRUG DIFFUSION; DRUG RELEASE; DRUG-ELUTING STENTS; EVEROLIMUS; IN-VITRO; INTRAVASCULAR; LOCAL DRUG DELIVERY; PHARMACOKINECTICS; RESTENOSIS; STENTING; THEORETICAL MODELS; TIME-DEPENDENT;

ARTIFICIAL ORGANS; DIFFUSION; DIFFUSION COATINGS; DRUG DELIVERY; MODELS; THICKNESS MEASUREMENT;

PLASTIC COATINGS;

ETHYLENE VINYL ALCOHOL COPOLYMER; EVEROLIMUS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG COATING; DRUG DETERMINATION; DRUG DIFFUSION; DRUG ELUTING STENT; DRUG RELEASE; DRUG TISSUE LEVEL; NONHUMAN; QUANTITATIVE ANALYSIS; SWINE; THEORETICAL MODEL;

ANIMALS; ARTERIES; COATED MATERIALS, BIOCOMPATIBLE; DIFFUSION; DRUG-ELUTING STENTS; MODELS, BIOLOGICAL; POLYETHYLENE GLYCOLS; POLYVINYL ALCOHOL; SIROLIMUS; SUS SCROFA;

EID: 81855194281     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33246     Document Type: Article

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