Identification of promethazine as an amyloid-binding molecule using a fluorescence high-throughput assay and MALDI imaging mass spectrometry

NeuroImage: Clinical

Volumn 2, Issue 1, 2013, Pages 620-629

  McClure, Richard A ^a,b   Chumbley, Chad W ^c   Reyzer, Michelle L ^b,c   Wilson, Kevin ^a,b   Caprioli, Richard M ^b,c,d   Gore, John C ^a,b,c,d   Pham, Wellington ^a,b,d  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Alzheimer's disease; Amyloid plaques; MALDI IMS; Neuroimaging; Promethazine

Indexed keywords

AMYLOID; ASTEMIZOLE; HALOPERIDOL; MINOCYCLINE; NALTREXONE; PROMETHAZINE; THIOFLAVINE;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; BLOOD BRAIN BARRIER; BRAIN; BRAIN PERFUSION; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; HIGH THROUGHPUT SCREENING; PROTEIN BINDING;

EID: 84877967931     PISSN: None     EISSN: 22131582     Source Type: Journal    
DOI: 10.1016/j.nicl.2013.04.015     Document Type: Article

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