-
1
-
-
79956319051
-
Progress and challenges in translating the biology of atherosclerosis
-
Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature. 2011;473:317-325.
-
(2011)
Nature.
, vol.473
, pp. 317-325
-
-
Libby, P.1
Ridker, P.M.2
Hansson, G.K.3
-
2
-
-
67650720510
-
Immune and infammatory mechanisms of atherosclerosis (*)
-
Galkina E, Ley K. Immune and infammatory mechanisms of atherosclerosis (*). Annu Rev Immunol. 2009;27:165-197.
-
(2009)
Annu Rev Immunol.
, vol.27
, pp. 165-197
-
-
Galkina, E.1
Ley, K.2
-
3
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
-
Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008;359:2195-2207.
-
(2008)
N Engl J Med.
, vol.359
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
Genest, J.4
Gotto, Jr.A.M.5
Kastelein, J.J.6
Koenig, W.7
Libby, P.8
Lorenzatti, A.J.9
MacFadyen, J.G.10
Nordestgaard, B.G.11
Shepherd, J.12
Willerson, J.T.13
Glynn, R.J.14
-
4
-
-
67949124665
-
Testing the infammatory hypothesis of atherothrombosis: Scientifc rationale for the Cardiovascular Infammation Reduction Trial (CIRT)
-
Ridker PM. Testing the infammatory hypothesis of atherothrombosis: scientifc rationale for the Cardiovascular Infammation Reduction Trial (CIRT). J Thromb Haemost. 2009;7(suppl 1):332-339.
-
(2009)
J Thromb Haemost.
, vol.7
, Issue.SUPPL. 1
, pp. 332-339
-
-
Ridker, P.M.1
-
5
-
-
80053644777
-
Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and design of the Canakinumab Anti-infammatory Thrombosis Outcomes Study (CANTOS)
-
Ridker PM, Thuren T, Zalewski A, Libby P. Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-infammatory Thrombosis Outcomes Study (CANTOS). Am Heart J. 2011;162:597-605.
-
(2011)
Am Heart J.
, vol.162
, pp. 597-605
-
-
Ridker, P.M.1
Thuren, T.2
Zalewski, A.3
Libby, P.4
-
6
-
-
0019491124
-
The role of the monocyte in atherogenesis, I: Transition of blood-borne monocytes into foam cells in fatty lesions
-
Gerrity RG. The role of the monocyte in atherogenesis, I: transition of blood-borne monocytes into foam cells in fatty lesions. Am J Pathol. 1981;103:181-190.
-
(1981)
Am J Pathol.
, vol.103
, pp. 181-190
-
-
Gerrity, R.G.1
-
7
-
-
0021261107
-
Studies of hypercholesterolemia in the nonhuman primate, I: Changes that lead to fatty streak formation
-
Faggiotto A, Ross R, Harker L. Studies of hypercholesterolemia in the nonhuman primate, I: changes that lead to fatty streak formation. Arteriosclerosis. 1984;4:323-340.
-
(1984)
Arteriosclerosis.
, vol.4
, pp. 323-340
-
-
Faggiotto, A.1
Ross, R.2
Harker, L.3
-
8
-
-
0028677527
-
Local expression of infammatory cytokines in human atherosclerotic plaques
-
Wilcox JN, Nelken NA, Coughlin SR, Gordon D, Schall TJ. Local expression of infammatory cytokines in human atherosclerotic plaques. J Atheroscler Thromb. 1994;1(suppl 1):10-13.
-
(1994)
J Atheroscler Thromb.
, vol.1
, Issue.SUPPL. 1
, pp. 10-13
-
-
Wilcox, J.N.1
Nelken, N.A.2
Coughlin, S.R.3
Gordon, D.4
Schall, T.J.5
-
9
-
-
0025281588
-
Minimally modifed low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells
-
Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM. Minimally modifed low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci U S A. 1990;87:5134-5138.
-
(1990)
Proc Natl Acad Sci U S A.
, vol.87
, pp. 5134-5138
-
-
Cushing, S.D.1
Berliner, J.A.2
Valente, A.J.3
Territo, M.C.4
Navab, M.5
Parhami, F.6
Gerrity, R.7
Schwartz, C.J.8
Fogelman, A.M.9
-
10
-
-
0028316908
-
Molecular cloning and functional expression of two monocyte chemoat-tractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails
-
Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR. Molecular cloning and functional expression of two monocyte chemoat-tractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci U S A. 1994;91:2752-2756.
-
(1994)
Proc Natl Acad Sci U S A.
, vol.91
, pp. 2752-2756
-
-
Charo, I.F.1
Myers, S.J.2
Herman, A.3
Franci, C.4
Connolly, A.J.5
Coughlin, S.R.6
-
11
-
-
0032572719
-
Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis
-
Boring L, Gosling J, Cleary M, Charo IF. Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 1998;394:894-897.
-
(1998)
Nature.
, vol.394
, pp. 894-897
-
-
Boring, L.1
Gosling, J.2
Cleary, M.3
Charo, I.F.4
-
12
-
-
0032134003
-
Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-defcient mice
-
Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, Rollins BJ. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-defcient mice. Mol Cell. 1998;2:275-281.
-
(1998)
Mol Cell.
, vol.2
, pp. 275-281
-
-
Gu, L.1
Okada, Y.2
Clinton, S.K.3
Gerard, C.4
Sukhova, G.K.5
Libby, P.6
Rollins, B.J.7
-
14
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol. 2005;5:953-964.
-
(2005)
Nat Rev Immunol.
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
15
-
-
84876207357
-
Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal
-
Carlin LM, Stamatiades EG, Auffray C, Hanna RN, Glover L, Vizcay-Barrena G, Hedrick CC, Cook HT, Diebold S, Geissmann F. Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal. Cell. 2013;153:362-375.
-
(2013)
Cell.
, vol.153
, pp. 362-375
-
-
Carlin, L.M.1
Stamatiades, E.G.2
Auffray, C.3
Hanna, R.N.4
Glover, L.5
Vizcay-Barrena, G.6
Hedrick, C.C.7
Cook, H.T.8
Diebold, S.9
Geissmann, F.10
-
16
-
-
84878000143
-
Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice
-
Majmudar M, Keliher E, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, Dickneite G, Chen JW, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M. Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice. Circulation. 2013;127:2038-2046.
-
(2013)
Circulation.
, vol.127
, pp. 2038-2046
-
-
Majmudar, M.1
Keliher, E.2
Heidt, T.3
Leuschner, F.4
Truelove, J.5
Sena, B.F.6
Gorbatov, R.7
Iwamoto, Y.8
Dutta, P.9
Wojtkiewicz, G.10
Courties, G.11
Sebas, M.12
Borodovsky, A.13
Fitzgerald, K.14
Nolte, M.W.15
Dickneite, G.16
Chen, J.W.17
Anderson, D.G.18
Swirski, F.K.19
Weissleder, R.20
Nahrendorf, M.21
more..
-
17
-
-
36549033197
-
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
-
Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204:3037-3047.
-
(2007)
J Exp Med.
, vol.204
, pp. 3037-3047
-
-
Nahrendorf, M.1
Swirski, F.K.2
Aikawa, E.3
Stangenberg, L.4
Wurdinger, T.5
Figueiredo, J.L.6
Libby, P.7
Weissleder, R.8
Pittet, M.J.9
-
18
-
-
84863115989
-
Rapid monocyte kinetics in acute myocar-dial infarction are sustained by extramedullary monocytopoiesis
-
Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M. Rapid monocyte kinetics in acute myocar-dial infarction are sustained by extramedullary monocytopoiesis. J Exp Med. 2012;209:123-137.
-
(2012)
J Exp Med.
, vol.209
, pp. 123-137
-
-
Leuschner, F.1
Rauch, P.J.2
Ueno, T.3
Gorbatov, R.4
Marinelli, B.5
Lee, W.W.6
Dutta, P.7
Wei, Y.8
Robbins, C.9
Iwamoto, Y.10
Sena, B.11
Chudnovskiy, A.12
Panizzi, P.13
Keliher, E.14
Higgins, J.M.15
Libby, P.16
Moskowitz, M.A.17
Pittet, M.J.18
Swirski, F.K.19
Weissleder, R.20
Nahrendorf, M.21
more..
-
19
-
-
77951155798
-
CCR2 mediates hematopoietic stem and progenitor cell traffcking to sites of infammation in mice
-
Si Y, Tsou CL, Croft K, Charo IF. CCR2 mediates hematopoietic stem and progenitor cell traffcking to sites of infammation in mice. J Clin Invest. 2010;120:1192-1203.
-
(2010)
J Clin Invest.
, vol.120
, pp. 1192-1203
-
-
Si, Y.1
Tsou, C.L.2
Croft, K.3
Charo, I.F.4
-
21
-
-
77953642757
-
Treatment with 5-lipoxygenase inhibitor VIA-2291 (Atreleuton) in patients with recent acute coronary syndrome
-
Tardif JC, L'allier PL, Ibrahim R, Grégoire JC, Nozza A, Cossette M, Kouz S, Lavoie MA, Paquin J, Brotz TM, Taub R, Pressacco J. Treatment with 5-lipoxygenase inhibitor VIA-2291 (Atreleuton) in patients with recent acute coronary syndrome. Circ Cardiovasc Imaging. 2010;3:298-307.
-
(2010)
Circ Cardiovasc Imaging.
, vol.3
, pp. 298-307
-
-
Tardif, J.C.1
L'Allier, P.L.2
Ibrahim, R.3
Grégoire, J.C.4
Nozza, A.5
Cossette, M.6
Kouz, S.7
Lavoie, M.A.8
Paquin, J.9
Brotz, T.M.10
Taub, R.11
Pressacco, J.12
-
22
-
-
80155200721
-
Therapeutic siRNA silencing in infammatory monocytes in mice
-
Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M. Therapeutic siRNA silencing in infammatory monocytes in mice. Nat Biotechnol. 2011;29:1005-1010.
-
(2011)
Nat Biotechnol.
, vol.29
, pp. 1005-1010
-
-
Leuschner, F.1
Dutta, P.2
Gorbatov, R.3
Novobrantseva, T.I.4
Donahoe, J.S.5
Courties, G.6
Lee, K.M.7
Kim, J.I.8
Markmann, J.F.9
Marinelli, B.10
Panizzi, P.11
Lee, W.W.12
Iwamoto, Y.13
Milstein, S.14
Epstein-Barash, H.15
Cantley, W.16
Wong, J.17
Cortez-Retamozo, V.18
Newton, A.19
Love, K.20
Libby, P.21
Pittet, M.J.22
Swirski, F.K.23
Koteliansky, V.24
Langer, R.25
Weissleder, R.26
Anderson, D.G.27
Nahrendorf, M.28
more..
-
23
-
-
79952316203
-
Effect of CC chemokine receptor 2 CCR2 blockade on serum C-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region
-
Gilbert J, Lekstrom-Himes J, Donaldson D, Lee Y, Hu M, Xu J, Wyant T, Davidson M; MLN1202 Study Group. Effect of CC chemokine receptor 2 CCR2 blockade on serum C-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region. Am J Cardiol. 2011;107:906-911.
-
(2011)
Am J Cardiol.
, vol.107
, pp. 906-911
-
-
Gilbert, J.1
Lekstrom-Himes, J.2
Donaldson, D.3
Lee, Y.4
Hu, M.5
Xu, J.6
Wyant, T.7
Davidson, M.8
-
24
-
-
84878002397
-
Orally-administered chemokine receptor CCR2 antagonist CCX140-B in type 2 diabetes: A pilot double-blind, randomized clinical trial
-
Hanefeld M, Schell E, Gouni-Berthold I, Melichar M, Vesela I, Johnson D, Miao S, Sullivan T, Jaen J, Schall T, Bekker P; CCX140-B Diabetes Study Group. Orally-administered chemokine receptor CCR2 antagonist CCX140-B in type 2 diabetes: a pilot double-blind, randomized clinical trial. Diabetes Metab Rev. 2012;3:1-8.
-
(2012)
Diabetes Metab Rev.
, vol.3
, pp. 1-8
-
-
Hanefeld, M.1
Schell, E.2
Gouni-Berthold, I.3
Melichar, M.4
Vesela, I.5
Johnson, D.6
Miao, S.7
Sullivan, T.8
Jaen, J.9
Schall, T.10
Bekker, P.11
-
25
-
-
0032908874
-
The utility of animal models in the preclinical study of interventions to prevent human coronary artery restenosis: Analysis and recommendations: On behalf of the Subcommittee on Animal Cellular and Molecular Models of Thrombosis and Haemostasis of the Scientifc and Standardization Committee of the International Society on Thrombosis and Haemostasis
-
Johnson GJ, Griggs TR, Badimon L. The utility of animal models in the preclinical study of interventions to prevent human coronary artery restenosis: analysis and recommendations: on behalf of the Subcommittee on Animal, Cellular and Molecular Models of Thrombosis and Haemostasis of the Scientifc and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost. 1999;81:835-843.
-
(1999)
Thromb Haemost.
, vol.81
, pp. 835-843
-
-
Johnson, G.J.1
Griggs, T.R.2
Badimon, L.3
-
27
-
-
55549106152
-
Coordinating innate immune cells to optimize microbial killing
-
Serbina NV, Pamer EG. Coordinating innate immune cells to optimize microbial killing. Immunity. 2008;29:672-674.
-
(2008)
Immunity.
, vol.29
, pp. 672-674
-
-
Serbina, N.V.1
Pamer, E.G.2
|